In a new study published in Nature Communications Biology, wildlife rangers from the Uganda Wildlife Authority have demonstrated their ability to generate precise and reliable data on lion populations in Uganda’s Nile Delta, a critical stronghold for African lions. The study reveals that wildlife rangers, a critical component of global conservation efforts but often underutilised in scientific research, can play a pivotal role in the conservation science surrounding the world’s most beloved big cat. Rangers are effective at monitoring lions and are an underutilised resource The study showed rangers ...

One of the most notorious mass extinction events in modern times occurred on a hilltop in coastal Ecuador in the 1980s. Ninety species of plants known from nowhere else on Earth—many of them new to science and not yet given a name—went extinct when the last cloud forests of the Centinela range were cleared for agriculture. The cautionary tale of Centinela has long been a driving force in the fight to save the world’s rainforests. But did it really happen? In a new study published in Nature Plants, an international team of botanists reveals that, indeed, it did not happen. The researchers – who spent years of scouring natural history museums, biodiversity databases, ...

About The Study: Among individuals with ulcerative colitis, the allele HLA-DRB1*01:03 was associated with severe ulcerative colitis requiring major operation, hospitalization, and systemic corticosteroid use compared with less severe disease. HLA-DRB1*01:03 has previously been linked to ulcerative colitis incidence. This study supports earlier, targeted genetic studies comparing patients with healthy controls reporting an association with total disease and severe disease requiring colectomy. Corresponding Author: To contact the corresponding author, Marie Vibeke Vestergaard, MSc, email marievv@dcm.aau.dk. To access the embargoed study: Visit our ...

Montpellier, France – 15 October 2024. In a captivating Genomic Press Interview published on October 15, 2024, in the peer-reviewed journal Genomic Psychiatry (Genomic Press), Professor Philippe Courtet shares groundbreaking perspectives on suicide prevention and mental health care. As an influential PU-PH (Professeur des Universités-Praticien Hospitalier), he is a Professor of Psychiatry at the University of Montpellier, France, and head of emergency psychiatry at the University Hospital of, Professor Courtet stands at the forefront of ...

Miscarriage, or early pregnancy loss, can have devastating emotional effects, but it is poorly managed in Canada. A review published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.231489 provides guidance to physicians on how to diagnose and manage this condition and calls for referral to outpatient early pregnancy assessment clinics (EPACs) as well as a compassionate approach. October 15 is Pregnancy and Infant Loss Remembrance Day. Data suggest that 15%–20% of all confirmed pregnancies result in miscarriage, with ...

A joint research group led by Jonghyun Kim and Jun Ohashi of the University of Tokyo has demonstrated that the majority of immigration to the Japanese Archipelago in the Yayoi and Kofun periods (between 3000 BCE and 538 CE) came from the Korean Peninsula. The researchers analyzed the complete genome of a “Yayoi” individual and found that, among the non-Japanese populations, the results bore the most similarity to Korean populations. Although it is widely accepted that modern Japanese populations have a dual ancestry, the discovery provides insight into the details of immigration patterns to the ...

DURHAM, N.C. -- Since 1970, 37 countries have cut the probability of their citizens dying before they reach age 70 in half, a milestone that signals the remarkable progress many countries have made in preventing and treating disease. But a new report argues that this goal isn’t out of reach for any country that chooses to cut its premature mortality, even those afflicted by war or poverty. The report, published Oct. 14 by The Lancet Commission on Investing in Health, lays out a roadmap for every nation that chooses to do so to cut ...

A team of 50 leading international experts, the Lancet Commission on Investing in Health (CIH), explored this question, resulting in clear, actionable, and achievable measures for achieving this ambitious goal worldwide. Six of the 50 commission members are affiliated with the Bergen Centre for Ethics and Priority Setting in Health (BCEPS), a Norwegian Centre of Excellence based at the University of Bergen, Norway, including BCEPS Director and Professor Ole Frithjof Norheim, BCEPS PhD Research Fellow Sarah Bolongaita, and BCEPS-affiliated researchers Angela Chang (University ...

Copenhagen, Denmark: Wearing a helmet can prevent brain injury and deaths in cyclists, yet many do not wear a helmet. New research presented at the European Emergency Medicine Congress today (Tuesday) suggests that this is largely due to issues of convenience and comfort. [1]   The study also suggests that more adult cyclists would wear helmets if they were encouraged and incentivised to do so, for example if they were provided with a free helmet, education, and periodic reminders.   The research was presented by Dr Steven Friedman, an emergency doctor at Toronto General Hospital and associate professor at the University ...

Copenhagen, Denmark: Half of all patients with sepsis admitted to an emergency medical department died within two years, according to Danish researchers investigating factors that could predict outcomes for these patients.   Dr Finn E. Nielsen, a senior scientist in the Department of Clinical Epidemiology at Aarhus University Hospital, Denmark, told the European Emergency Medicine Congress today (Tuesday) [1] that he and his colleagues examined deaths over a long follow-up period in a prospective study of 714 adult patients admitted to the emergency department with sepsis. Their findings ...

Embargoed for release until 5:00 p.m. ET on Monday 14 October 2024     @Annalsofim          Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.     ...

St. Louis, MO (October 14, 2024) According to the Centers for Disease Control, nearly 20% of children and teens are considered obese. Research shows it can have a dramatic impact on a variety of health conditions, including arthritis, heart conditions and other metabolic problems, and the American Academy of Pediatrics now recommends early and intensive treatment to combat obesity. Over the last four years, Shriners Children’s St. Louis researchers have been working to develop a new way to prevent the effects of childhood obesity.    Using gene therapy, Shriners Children’s St. Louis Director of Research Dr. Farshid Guilak and Senior Scientist Dr. Ruhang Tang ...

About The Study: Mpox is a viral infection transmitted primarily through close skin to skin contact that typically causes a self-resolving illness but can result in severe illness and death in immunocompromised individuals. First-line therapy is supportive care, although patients with severe mpox infection may be treated with advanced therapeutics. Mpox vaccination is effective and, if available, should be offered to individuals at risk of exposure to mpox. Corresponding Author: To contact the corresponding author, Jason Zucker, MD, MS, email Jz2700@cumc.columbia.edu. To access the embargoed study: Visit our For The Media ...

About The Study: Preexposure prophylaxis (PrEP) use increased between 2013 and 2023, with generic tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) being the most frequently prescribed medication since 2021. Injectable PrEP use was low likely because of barriers such as the high cost of stocking this expensive medication in clinics. Corresponding Author: To contact the corresponding author, Laura M. Mann, PhD, MPH, email lmann@cdc.gov. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2024.21493) Editor’s ...

About The Study: Most U.S. hospital websites explicitly included sexual and gender minority (SGM) populations in their nondiscrimination policies, but only a quarter of adult hospitals had an SGM-friendly clinician directory and provided information about SGM-related resources or hospital-based services. Pediatric hospitals more frequently posted SGM-related information than adult hospitals. Hospitals in states with more discriminatory policies were less likely to provide SGM-related information online. Corresponding Author: To contact the corresponding author, Alex S. Keuroghlian, MD, MPH, email akeuroghlian@mgb.org. To ...

Study finds use of naloxone by Good Samaritans is up, but not nearly enough Ohio State and National Registry of EMTs research highlights importance of public’s help in opioid overdose response COLUMBUS, Ohio – Use of a lifesaving drug to reverse opioid drug overdoses is growing, but not fast enough. That’s according to new research in JAMA Network Open from The Ohio State University College of Medicine, College of Public Health and the National Registry of Emergency Medical Technicians. In the first study of its kind, the research team looked at national use of naloxone by people without medical training to treat an opioid drug overdose.  “Naloxone ...

About The Study: In this study, adolescents with obesity prescribed a glucagon-like peptide 1 receptor agonists (GLP1R) had a lower incidence of suicidal ideation or attempts compared with matched patients not prescribed GLP1R who were treated with lifestyle intervention. These results suggest a favorable psychiatric safety profile of GLP1R in adolescents. The detected reduction in hazard ratios for suicidal ideation among adolescents with obesity prescribed GLP1R suggests potential avenues for future research. Corresponding Author: To contact the corresponding author, Liya Kerem, MD, MSc, email liya.em@gmail.com. To access the ...

About The Study: In this retrospective cohort study of children and adolescents ages 10 to 19, the risk of an incident diagnosis of type 2 diabetes was greater following a COVID-19 diagnosis than in children diagnosed with other respiratory infections. Further study is required to determine whether diabetes persists or reverses later in life.  Corresponding Author: To contact the corresponding author, Pauline Terebuh, MD, MPH, email pdt@case.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.39444) Editor’s Note: Please see the article for additional information, ...

About The Study: This cross-sectional study of nationally representative registry data found that cancer incidence recovered meaningfully in 2021 following substantial disruptions in 2020. However, incidence rates need to recover further to address the substantial number of patients with undiagnosed cancer during the pandemic.  Corresponding Author: To contact the corresponding author, Uriel Kim, MD, PhD, MBA, email uxk13@case.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.39263) Editor’s Note: Please ...

Medicare could save up to 74% of the money lost from discarded Alzheimer’s drug lecanemab by the simple introduction of a new vial size that would reduce the amount of unused medication that is thrown away, new research suggests. The researchers on the study, to be published October 14 in the peer-reviewed JAMA Internal Medicine, estimate that Medicare could waste up to $336 million annually due to discarded medication. Administered dosages are based on each patient’s body weight. But because the drug is currently available ...

​When we inhale, airborne chemicals enter our nose, creating the "odor" we detect. These chemicals are then expelled when we exhale. Each breath lasts 3–5 seconds, which seems to limit how quickly we can perceive odors. Chemical changes that occur within a single breath appear to be combined into one odor. Because of this, our sense of smell, or olfaction, is often considered a slow sense. Now, however, researchers led by Dr. ZHOU Wen from the Institute of Psychology of the Chinese Academy of Sciences have challenged this view. Their new study, ...

Leuven, 14 October 2024 - The human brain’s remarkably prolonged development is unique among mammals and is thought to contribute to our advanced learning abilities. Disruptions in this process may explain certain neurodevelopmental diseases. Now, a team of researchers led by Prof. Pierre Vanderhaeghen (VIB-KU Leuven), together with scientists of Columbia University and Ecole Normale Supérieure has discovered a link between two genes, present only in human DNA, and a key gene called SYNGAP1, which is mutated in intellectual disability and autism spectrum disorders. Their study, published in Neuron,  provides a surprisingly direct link between human brain ...

The future of wireless technology — from charging devices to boosting communication signals — relies on the antennas that transmit electromagnetic waves becoming increasingly versatile, durable and easy to manufacture. Researchers at Drexel University and the University of British Columbia believe kirigami, the ancient Japanese art of cutting and folding paper to create intricate three-dimensional designs, could provide a model for manufacturing the next generation of antennas. Recently published in the journal Nature Communications, research from the Drexel-UBC team showed how kirigami — a variation of origami — ...

Researchers from Peking University have conducted a comprehensive systematic review on the integration of machine learning into statistical methods for disease risk prediction models, shedding light on the potential of such integrated models in clinical diagnosis and screening practices. The study, led by Professor Feng Sun from the Department of Epidemiology and Biostatistics, School of Public Health, Peking University, has been published in Health Data Science. Disease risk prediction is crucial for early diagnosis and effective clinical decision-making. However, traditional statistical models, such as logistic regression and Cox proportional hazards regression, often ...

Some people believe that talking to your plants makes them thrive. While there’s limited scientific support for sound improving plant health, there’s a growing amount of evidence about the benefits of mechanical stimulation, like touch, wind or rain. Researchers reporting in ACS’ Journal of Agricultural and Food Chemistry examined the impact of watering practices on tomato plants. They found that the size of the water droplets affected plant growth and resistance to pests and pathogens. Climate change threatens crop production as rising ...