Significant variations in survival times of early onset dementia by clinical subtype
2025-11-05
The survival rates of people with early onset dementia—diagnosed before the age of 65—vary considerably by clinical type, but sex, age, family history and co-existing conditions aren't specific risk factors, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.
Although the survival of those afflicted by dementia in older age is shorter, the overall impact on the risk of death from any cause is even greater in those with early onset disease than it is in others of comparable ...
Research finds higher rare risk of heart complications in children after COVID-19 infection than after vaccination
2025-11-05
The study is the largest of its kind in this population, and is published in The Lancet Child and Adolescent Health. It was led by scientists at the Universities of Cambridge and Edinburgh, and University College London, with support from the BHF Data Science Centre at Health Data Research UK.
Principal author Dr Alexia Sampri, University of Cambridge, said:
“Our whole-population study during the pandemic showed that although these conditions were rare, children and young people were more likely to experience heart, vascular or inflammatory problems after a COVID-19 infection ...
Oxford researchers develop ‘brain-free’ robots that move in sync, powered entirely by air
2025-11-05
UNDER EMBARGO UNTIL 00:01 GMT WEDNESDAY 05 NOVEMBER 2025
Oxford researchers develop ‘brain-free’ robots that move in sync, powered entirely by air
A team led by the University of Oxford has developed a new class of soft robots that operate without electronics, motors, or computers - using only air pressure. The study, published today (05 Nov) in Advanced Materials, shows that these ‘fluidic robots’ can generate complex, rhythmic movements and even automatically synchronise their actions.
Professor Antonio Forte (Department of Engineering Science, University of Oxford, Lead of RADLab) said: “We are excited ...
The science behind people who never forget a face
2025-11-05
What is it that makes a super recogniser – someone with extraordinary face recognition abilities – better at remembering faces than the rest of us?
According to new research carried out by cognitive scientists at UNSW Sydney, it’s not how much of a face they can take in – it comes down to the quality of the information their eyes focus on.
“Super-recognisers don’t just look harder, they look smarter. They choose the most useful parts of a face to take in,” says Dr James Dunn, lead author on the research that published ...
Study paints detailed picture of forest canopy damage caused by ‘heat dome’
2025-11-04
CORVALLIS, Ore. – A satellite imagery analysis shows that the 2021 “heat dome” scorched almost 5% of the forested area in western Oregon and western Washington, turning foliage in canopies from a healthy green to red or orange, sometimes within a matter of hours.
Damage to foliage leads to a range of problems for trees including reduced photosynthesis and increased vulnerability to pests and disease, scientists at Oregon State University say.
The study by researchers at OSU and ...
New effort launched to support earlier diagnosis, treatment of aortic stenosis
2025-11-04
DALLAS, November 3, 2025 — People living with aortic stenosis (AS) could gain earlier access to innovative care and treatment thanks to a new effort from the American Heart Association designed to boost clinical trial participation and speed diagnosis of this common but underdiagnosed heart valve condition.
AS is characterized by the narrowing of the aortic valve opening, which restricts blood flow from the heart to the body. Untreated, this can lead to severe complications, including heart failure and death.
The American Heart Association, devoted to changing the future to a world of healthier lives for all, is expanding its support for patients ...
Registration and Abstract Submission Open for “20 Years of iPSC Discovery: A Celebration and Vision for the Future,” 20-22 October 2026, Kyoto, Japan
2025-11-04
The International Society for Stem Cell Research (ISSCR) today announced that registration and abstract submission are open for the ISSCR International Symposium: 20 Years of iPSC Discovery: A Celebration and Vision for the Future, co-sponsored by the Japanese Society for Regenerative Medicine. The symposium will take place 20–22 October 2026 in Kyoto, Japan.
Developed in partnership with the Center for iPS Cell Research and Application (CiRA) at Kyoto University, the scientific program is chaired by Shinya Yamanaka, recipient of the 2012 Nobel Prize in Physiology or Medicine for the ...
Half-billion-year-old parasite still threatens shellfish
2025-11-04
A new study has unexpectedly discovered that a common parasite of modern oysters actually started infecting bivalves hundreds of millions of years before the dinosaurs went extinct.
The research, published in iScience, used high-resolution 3D scans to look inside 480-million-year-old shells from a Moroccan site known for its exceptionally well-preserved sea life. The scans revealed a series of distinctive patterns etched both on the surface of the fossils and hidden inside them.
“The marks weren’t random scratches,” said Karma Nanglu, a UC Riverside paleobiologist who led the research. “We saw seven or eight of these perfect question mark shapes on each ...
Engineering a clearer view of bone healing
2025-11-04
Healing a broken bone can take months, and knowing whether recovery is on track often takes just as long. Doctors typically rely on periodic X-rays, capturing two-dimensional images to see how the bone is growing back together. Patients return for follow-up scans every few weeks or months, repeating the cycle until the bone shows signs of complete healing.
Healing of shin bone (tibia) fractures, in particular, slows or stalls up to 25% of the time. Factors such as age or underlying health conditions like diabetes can influence the speed of fracture healing. Delayed or incomplete ...
Detecting heart issues in breast cancer survivors
2025-11-04
As breast cancer survival rates continue to climb — 4.3 million women in the U.S. are currently living with a history of the disease and in the next 10 years that number is expected to rise by another million — heart health has become an increasingly important part of survivorship care.
Certain breast cancer therapies, while lifesaving, can also place stress on the heart, raising important questions about who might benefit from closer monitoring.
But does every breast cancer survivor need ...
Moffitt study finds promising first evidence of targeted therapy for NRAS-mutant melanoma
2025-11-04
Moffitt Cancer Center researchers report the first clinical activity of a RAS inhibitor in patients with NRAS-mutant melanoma.
The investigational drug daraxonrasib (RMC-6236) and its preclinical counterpart RMC-7977 bind active RAS proteins (NRAS, HRAS, KRAS) and block downstream signaling that drives tumor growth, survival and immune escape.
In laboratory models, treatment led to increased infiltration of activated T cells, reduction of suppressive immune cells and tumor eradication only when the immune ...
Lay intuition as effective at jailbreaking AI chatbots as technical methods
2025-11-04
UNIVERSITY PARK, Pa. — It doesn’t take technical expertise to work around the built-in guardrails of artificial intelligence (AI) chatbots like ChatGPT and Gemini, which are intended to ensure that the chatbots operate within a set of legal and ethical boundaries and do not discriminate against people of a certain age, race or gender. A single, intuitive question can trigger the same biased response from an AI model as advanced technical inquiries, according to a team led by researchers at Penn State.
“A lot of research on AI bias has relied on sophisticated ...
USC researchers use AI to uncover genetic blueprint of the brain’s largest communication bridge
2025-11-04
For the first time, a research team led by the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has mapped the genetic architecture of a crucial part of the human brain known as the corpus callosum—the thick band of nerve fibers that connects the brain’s left and right hemispheres. The findings open new pathways for discoveries about mental illness, neurological disorders and other diseases related to defects in this part of the brain.
The corpus callosum is critical for nearly everything the brain does, from coordinating ...
Tiny swarms, big impact: Researchers engineering adaptive magnetic systems for medicine, energy and environment
2025-11-04
Rice University is partnering with researchers at the University of Washington, Columbia University and Louisiana State University on a $2 million award from the National Science Foundation to revolutionize how materials and microrobots can be designed, controlled and applied in real-world environments.
Funded through NSF’s Designing Materials to Revolutionize and Engineer our Future (DMREF) program, the four-year project — Adaptive and Responsive Magnetic Swarms (ARMS) — aims to create microscopic robotic swarms that move and think collectively, much like schools of fish or flocks of birds.
Led by principal investigator Zach ...
MSU study: How can AI personas be used to detect human deception?
2025-11-04
EAST LANSING, Mich. – Can an AI persona detect when a human is lying – and should we trust it if it can? Artificial intelligence, or AI, has had many recent advances and continues t evolve in scope and capability. A new Michigan State University–led study is diving deeper into how well AI can understand humans by using it to detect human deception.
In the study, published in the Journal of Communication, researchers from MSU and the University of Oklahoma conducted 12 experiments with over 19,000 AI participants to examine how well AI personas were ...
Slowed by sound: A mouse model of Parkinson’s Disease shows noise affects movement
2025-11-04
In the development of Parkinson’s disease, it may not be a good idea to turn the amp to 11. High-volume noise exposure produced motor deficits in a mouse model of early-stage Parkinson’s disease, and established a link between the auditory processing and movement areas of the brain, according to a study published November 4th in the open-access journal PLOS Biology by Pei Zhang from the Huazhong University of Science and Technology in Wuhan, China, and colleagues.
The environment can play an important role in the development of Parkinson’s disease, but how sound volume in particular might impact the severity of symptoms was unknown. To understand how ...
Demographic shifts could boost drug-resistant infections across Europe
2025-11-04
The rates of bloodstream infections caused by drug-resistant bacteria will increase substantially across Europe in the next five years, driven largely by aging populations, according to a new paper published November 4th in the open-access journal PLOS Medicine by Gwenan Knight of the London School of Hygiene and Tropical Medicine, UK, and colleagues.
Antimicrobial resistance (AMR) is a global public health crisis. To effectively target interventions and track progress toward international goals, accurately estimating how the AMR burden will change over time is necessary.
In ...
Insight into how sugars regulate the inflammatory disease process
2025-11-04
New research has updated our understanding of how sugars, known as glycans, help immune cells move into skin in the inflammatory disease, psoriasis.
The paper entitled “Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation” published in the journal Science Signaling.
The lead authors are Dr Amy Saunders from Lancaster University and Dr Douglas Dyer from the University of Manchester, with their joint PhD student, ...
PKU scientists uncover climate impacts and future trends of hailstorms in China
2025-11-04
Peking University, November 4, 2025: A research team led by Professor Zhang Qinghong and Li Rumeng from the Department of Atmospheric and Oceanic Sciences at Peking University (PKU) School of Physics, has found that hailstorms in China have surged since the Industrial Revolution, likely due to human-driven climate warming. The study, published in Nature Communications in September 2025, combines historical records, meteorological data, and artificial intelligence to track long-term hailstorm trends.
Why It Matters:
Hail can fall fast and hit hard. Apart from smashing crops and damaging homes, it may even endanger lives. After 2024’s record-breaking ...
Computer model mimics human audiovisual perception
2025-11-04
A neural computation first discovered in insects has been shown to explain how humans combine sight and sound – even when illusions trick us into “hearing” what we do not see. Now, researcher Dr Cesare Parise from the University of Liverpool, UK, has created a biologically grounded model based on this computation, which can take in real-life audiovisual information instead of more abstract parameters used in previous models.
Parise’s research, published today in eLife as the final Version of ...
AC instead of DC: A game-changer for VR headsets and near-eye displays
2025-11-04
WASHINGTON, Nov. 4, 2025 — LEDs, or light-emitting diodes, are essential components in near-eye displays like virtual reality and augmented reality headsets and smart glasses, along with electronics like cameras and medical equipment.
Conventional LEDs use direct current power, which requires two contacts, like the positive and negative contacts to connect a battery. As device form factors continue to shrink, fabricating nano-LEDs requires each of the hundreds of microscopic components to touch both contacts, which presents a complicated alignment problem for device manufacturers.
In Applied Physics Letters, ...
Prevention of cardiovascular disease events and deaths among black adults via systolic blood pressure equity
2025-11-04
About The Study: The findings of this modeling study suggest that achieving systolic blood pressure equity between non-Hispanic Black and white adults could substantially reduce the number of cardiovascular disease events and deaths experienced by non-Hispanic Black U.S. adults. Initiatives to maintain normal blood pressure and achieve blood pressure control for individuals with hypertension could have a substantial impact on health equity in the U.S.
Corresponding Author: To contact the corresponding author, Shakia T. ...
Facility-based uptake of colorectal cancer screening in 45- to 49-year-olds after US guideline changes
2025-11-04
About The Study: The findings of this cohort study suggest that facility-based colorectal cancer screening among adults ages 45 to 49 increased nearly 10-fold following U.S. Preventive Services Task Force (USPSTF) guideline changes, far exceeding growth among those ages 50 to 75. This rapid adoption highlights early implementation by practitioners and patients. Although screening rates among adults ages 50 to 75 increased during the study period, the accelerated growth among those ages 45 to 49 reflected guideline ...
Scientists uncover hidden nuclear droplets that link multiple leukemias and reveal a new therapeutic target
2025-11-04
A hidden structure inside the cell is rewriting how scientists understand leukemia. Beneath the microscope, what looked like disorder turned out to follow a simple physical rule – one that connects several major mutations behind the disease.
In new research from Baylor College of Medicine published in Cell, scientists reveal that different genetic drivers of leukemia use the same secret compartments inside the cell nucleus to keep cancer growing. The finding points to a shared physical target that could inspire new kinds of treatments.
The ...
A new patch could help to heal the heart
2025-11-04
CAMBRIDGE, MA - MIT engineers have developed a flexible drug-delivery patch that can be placed on the heart after a heart attack to help promote healing and regeneration of cardiac tissue.
The new patch is designed to carry several different drugs that can be released at different times, on a pre-programmed schedule. In a study of rats, the researchers showed that this treatment reduced the amount of damaged heart tissue by 50 percent and significantly improved cardiac function.
If approved for use in humans, ...
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