Donors enable 445 TPDA awards to Neuroscience 2024
2024-10-04
CHICAGO – The Society for Neuroscience (SfN) is supporting 445 neuroscience trainees to attend Neuroscience 2024, SfN’s annual meeting and the world’s largest gathering of neuroscientists, through the Trainee Professional Development Award (TPDA) program. Over $560,000 in generous donations — the largest amount raised for this program — were contributed by individual donors to the Friends of SfN Fund, foundation and corporate supporters, and SfN Council. SfN Council leads this TPDA fundraising initiative and matched many of the donations.
“SfN is delighted to support ...
Gut bacteria engineered to act as tumor GPS for immunotherapies
2024-10-04
RESEARCH SUMMARY
Study Title: Nonpathogenic E. coli displaying decoy-resistant IL18 demonstrate potent anti-tumor responses and boost CAR-NK cell therapy
Publication: Nature Biotechnology
Dana-Farber Cancer Institute authors: Rizwan Romee, MD, Shaobo Yang, Michal Sheffer, PhD, David Barbie, MD, Catherine Wu, MD, Robert J. Soiffer, MD, Jerome Ritz, MD
Summary: Recent research has shown that certain forms of E. coli bacteria tend to colonize hypoxic ...
Are auditory magic tricks possible for a blind audience?
2024-10-04
Magic tricks make the impossible seem possible. Magicians have long captivated audiences with visual tricks, such as pulling a bunny from a hat or sawing someone in half, but tricks that rely on sound are scarce. A new article published in the Cell Press journal Trends in Cognitive Sciences on October 4 explores why creating a magical experience using only sound may be challenging and underscores the importance of making magic accessible to people with blindness.
"Given that magic is about the conflict between perceptual processes and our beliefs, we should be able to experience magic in ...
Research points to potential new treatment for aggressive prostate cancer subtype
2024-10-04
For more information, contact:
Nicole Fawcett, nfawcett@umich.edu
EMBARGOED for release at 11 a.m. ET Oct. 4, 2024
Research points to potential new treatment for aggressive prostate cancer subtype
In two separate papers, U-M researchers describe how a gene alteration drives prostate cancer and a potential degrader that stops it
ANN ARBOR, Michigan — When researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate cancer, they knew they needed to understand how this genetic alteration was driving cancer and how to target it with treatment.
In two new papers, ...
Studies examine growing US mental health safety net
2024-10-04
A decade after the establishment of the certified community behavioral health clinic (CCBHC) model, more than 60 percent of the US population has access to such facilities and the mental health and substance use disorder treatment services they provide, according to a new study led by researchers at the NYU School of Global Public Health. Moreover, these clinics are expanding the availability of crisis mental health services, including mobile crisis response teams and stabilization.
“Certified community behavioral health clinics have become a cornerstone of bipartisan strategies to increase access to and improve the ...
Social risk factor domains and preventive care services in US adults
2024-10-04
About The Study: This cross-sectional study of U.S. adults suggests that social risk factor domains were associated with decreased odds of receiving preventive services; this association was cumulative. There is a need to address social risk factors to optimize receipt of recommended preventive services.
Corresponding Author: To contact the corresponding author, Leonard E. Egede, MD, MS, email legede@buffalo.edu.
To access the embargoed study: Visit our For The Media website at ...
Online medication abortion direct-to-patient fulfillment before and after the Dobbs v Jackson decision
2024-10-04
About The Study: The findings of this study suggest that online pharmacies play an increasingly critical role in direct-to-patient medication abortion provision, especially with virtual-only platforms. These findings suggest that barriers to accessing online pharmacies for abortion care should be removed.
Corresponding Author: To contact the corresponding author, Caila Brander, MSc, email cbrander@ibisreproductivehealth.org.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.34675)
Editor’s ...
Black, Hispanic, and American Indian adolescents likelier than white adolescents to be tested for drugs, alcohol at pediatric trauma centers
2024-10-04
Injured adolescents from marginalized groups treated at pediatric trauma centers are more likely to be tested for drugs and alcohol than white adolescents, even when accounting for injury severity, a study led by researchers at UCLA and Children’s Hospital Los Angeles suggests.
The findings, to be published October 4 in the peer-reviewed JAMA Network Open, suggest that clinician biases could influence the selection of adolescents for biochemical substance use screening at pediatric trauma centers, said Dr. Jordan Rook, a general surgery resident at the David Geffen School of Medicine at UCLA and the study’s lead author. ...
Pterosaurs needed feet on the ground to become giants
2024-10-04
The evolutionary adaptations that allowed ancient pterosaurs to grow to enormous sizes have been pinpointed for the first time by palaeontologists in the Centre for Palaeobiology and Biosphere Evolution at the University of Leicester.
The discovery revealed a surprising twist – the ability to walk efficiently on the ground played a crucial role in determining how large the biggest flying animals could grow, with some reaching wingspans of up to 10 metres.
In a new study published today (4 October) in Current ...
Scientists uncover auditory “sixth sense” in geckos
2024-10-04
University of Maryland biologists identified a hidden sensory talent in geckos that’s shaking up what we thought we knew about animal hearing.
In a new study published in Current Biology on October 4, 2024, the researchers revealed that geckos use the saccule—a part of their inner ear traditionally associated with maintaining balance and body positioning—to detect low-frequency vibrations. According to the researchers, this special “sixth sense” also plays a complementary role to the geckos’ normal hearing and the way they sense ...
Almost half of persons who inject drugs (PWID) with endocarditis will die within five years; women are disproportionately affected
2024-10-04
LONDON, Ont. and REGINA, Sask. – People who inject drugs are dying at an alarming rate from endocarditis, a serious but treatable heart-valve infection.
But their odds of survival improve dramatically, even five years after their first admission to hospital, if they’re treated not just for heart infection but are also provided with addiction support while in hospital, a Canadian study shows.
The study also highlights that women who inject drugs are particularly vulnerable to endocarditis and are affected in disproportionately high numbers.
“Endocarditis is potentially lethal and always costly,” says Dr. Michael Silverman, an infectious ...
Experimental blood test improves early detection of pancreatic cancer
2024-10-04
GRAND RAPIDS, Mich. (Sept. 30, 2024) — An experimental blood test detects early-stage pancreatic cancer more effectively than other available tests, reports a new study published in Cancer Letters.
The findings pave the way for further evaluation of the test in a clinical setting, an important step toward approval as a potential diagnostic method for pancreatic cancer.
“Catching pancreatic cancer early dramatically improves survival, but our current tools for doing so are limited,” said the study’s co-corresponding author Brian Haab, Ph.D., a professor at Van Andel Institute. “Our results reveal that our combination ...
Groundbreaking wastewater treatment research led by Oxford Brookes targets global challenge of toxic ‘forever chemicals’
2024-10-04
Researchers at Oxford Brookes University have pioneered a groundbreaking method to tackle one of the world’s most persistent environmental threats—toxic chemicals in global water supplies.
They have developed a new machine called a hydrodynamic reactor that uses bubbles which form and collapse due to changes in pressure, a process called cavitation. The reactor removes toxic per- and poly-fluoroalkyl substances (PFAS), also known as “forever chemicals” from water.
PFAS chemicals were invented in the 1930s and used in convenience products ...
Jefferson Health awarded $2.4 million in PCORI funding
2024-10-04
PHILADELPHIA, Oct. 3, 2024 — Jefferson Health has been awarded $2.4 million by the Patient-Centered Outcomes Research Institute (PCORI) to implement evidence-based patient education and coaching programs for weight loss across Jefferson Primary Care.
U.S. adult obesity rates have risen to over 40% in the past two decades, increasing risks of diabetes, heart disease and premature death. Led by Baligh Yehia, M.D., MPP, MSHP, President of Jefferson Health, this project will implement sustainable health education programs ...
Cilta-cel found highly effective in first real-world study
2024-10-04
(WASHINGTON – October 4, 2024) In the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T therapy for multiple myeloma, patients experienced efficacy and safety results similar to those seen in clinical trials, according to results published today in Blood.
Of 236 patients who received cilta-cel infusions at 16 U.S. medical centers in 2022, 89% saw their cancer respond to the treatment and 70% had a complete response, meaning there was no detectable cancer after the treatment. These numbers ...
Unleashing the power of generative AI on smart collaborative innovation network platform to empower research and technology innovation
2024-10-04
A dedicated team of researchers from City University of Hong Kong (CityUHK) is pioneering cutting-edge generative artificial intelligence (GenAI) technologies on a collaborative innovation network platform, aimed at transforming science, technology and innovation (STI) services to empower research and innovation. This innovative project is set to revolutionise the related service delivery by creating a secure GenAI model and digitally transforming processes, thereby facilitating research development and technology innovation, while enhancing data security and service efficiency.
STI services, including ...
Revolutionizing cardiovascular risk assessment with AI
2024-10-04
A recent position paper in the Asia-Pacific Journal of Ophthalmology explores the transformative potential of artificial intelligence (AI) in ophthalmology. Led by Lama Al-Aswad, Professor of Ophthalmology and Irene Heinz Given and John La Porte Given Research Professor of Ophthalmology II, of the Scheie Eye Institute, the work represents a collaboration among researchers from Penn Engineering, Penn Medicine, the University of Michigan Kellogg Eye Center, St. John Eye Hospital in Jerusalem, and Gyeongsang National University College of Medicine in Korea.
With fundus photography enabling the visualization ...
Antarctic ‘greening’ at dramatic rate
2024-10-04
Vegetation cover across the Antarctic Peninsula has increased more than tenfold over the last four decades, new research shows.
The Antarctic Peninsula, like many polar regions, is warming faster than the global average, with extreme heat events in Antarctica becoming more common.
The new study – by the universities of Exeter and Hertfordshire, and the British Antarctic Survey – used satellite data to assess how much the Antarctic Peninsula has been “greening” in response to climate change.
It found that the area of vegetation ...
Winds of change: James Webb Space Telescope reveals elusive details in young star systems
2024-10-04
Every second, more than 3,000 stars are born in the visible universe. Many are surrounded by what astronomers call a protoplanetary disk – a swirling "pancake" of hot gas and dust from which planets form. The exact processes that give rise to stars and planetary systems, however, are still poorly understood.
A team of astronomers led by University of Arizona researchers has used NASA's James Webb Space Telescope to obtain some of the most detailed insights into the forces that shape protoplanetary disks. The observations offer glimpses into what our solar system may have looked like 4.6 billion years ago.
Specifically, the team was able to trace so-called ...
UC Merced co-leads initiative to combat promotion and tenure bias against Black and Hispanic faculty
2024-10-04
Black and Hispanic faculty members seeking promotion at research universities face career-damaging biases, with their scholarly production judged more harshly than that of their peers, according to a groundbreaking initiative co-led by the University of California, Merced that aims to uncover the roots of these biases and develop strategies for change.
Junior professors are generally evaluated and voted on for promotion and tenure by committees comprising senior colleagues. In one of the studies conducted by the research team, results suggest that faculty from underrepresented minorities received 7% more negative votes from ...
Addressing climate change and inequality: A win-win policy solution
2024-10-04
Climate change and economic inequality are deeply interconnected, with the potential to exacerbate each other if left unchecked. A new study published in Nature Climate Change sheds light on this critical relationship using data from eight large-scale Integrated Assessment Models (IAMs) to examine the distributional impacts of climate policies and climate risks. The study provides robust evidence that climate policies aligned with the Paris Agreement can mitigate long-term inequality while addressing climate change.
Led by Johannes Emmerling, Senior Scientist at the Euro-Mediterranean ...
Innovative catalyst produces methane using electricity
2024-10-04
Researchers at the University of Bonn and University of Montreal have developed a new type of catalyst and used it in their study to produce methane out of carbon dioxide and water in a highly efficient way using electricity. Methane can be used, for example, to heat apartments or as a starting material in the chemical industry. It is also the main component of natural gas. If it is produced using green electricity, however, it is largely climate neutral. The insights gained from the model system studied by the researchers can be transferred to large-scale technical ...
Liver X receptor beta: a new frontier in treating depression and anxiety
2024-10-04
Houston, Texas – In a state-of-the-art Bench to Bedside review published in the journal Brain Medicine (Genomic Press), researchers Dr. Xiaoyu Song and Professor Jan-Åke Gustafsson from the University of Houston and Karolinska Institutet (Sweden) shed light on the therapeutic potential of liver X receptor beta (LXRβ) in treating depression and anxiety. This comprehensive analysis marks a significant step forward in understanding the molecular underpinnings of mental health disorders and potentially revolutionizing their treatment.
LXRβ, a nuclear receptor initially known for its role in cholesterol metabolism and inflammation, is now emerging as a crucial ...
Improving fumaric acid production efficiency through a ‘more haste, less speed’ strategy
2024-10-04
As plastic waste continues to build up faster than it can decompose, the need for biodegradable solutions is evident.
Previously, Professor Yutaka Amao and his team at Osaka Metropolitan University’s Research Center for Artificial Photosynthesis succeeded in synthesizing fumaric acid, a raw material for biodegradable plastics from biomass-derived pyruvic acid and carbon dioxide. However, the fumaric acid production process reported earlier has a problem with producing undesirable substances as byproducts in addition to L-malic acid, which is ...
How future heatwaves at sea could devastate UK marine ecosystems and fisheries
2024-10-04
The oceans are warming at an alarming rate. 2023 shattered records across the world’s oceans, and was the first time that ocean temperatures exceeded 1oC over pre-industrial levels. This led to the emergence of a series of marine heatwave events across both hemispheres, from the waters around Japan, around South America, and across the wider North Atlantic. Marine heatwaves are periods of extremely warm sea temperatures that can form in quite localized hot spots but also span large parts of ocean ...
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