GLP-1RA order fills and out-of-pocket costs by race, ethnicity, and indication

JAMA Health Forum

2025-10-10

(Press-News.org) About The Study: In this cohort study, 40% of orders for glucagon-like peptide-1 receptor agonists (GLP-1RAs) were not filled. Non-Hispanic Black patients and Hispanic patients were less likely to fill orders than non-Hispanic white patients, and the non-Hispanic Black and Hispanic patients who filled their orders paid lower out-of-pocket costs. Out-of-pocket differences across groups may stem from differences in insurance coverage, use of different GLP-1RAs, or different cost thresholds for forgoing GLP-1RAs.

Corresponding Author: To contact the corresponding author, Ameet Sarpatwari, PhD, JD, email asarpatwari@hsph.harvard.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamahealthforum.2025.4258)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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GLP-1RA order fills and out-of-pocket costs by race, ethnicity, and indication

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