JACC recognizes five recipients of the William W. Parmley Young Author Achievement Award
2025-03-28
JACC, the flagship journal of the American College of Cardiology, is recognizing five primary authors with the William W. Parmley Young Author Achievement Award, due to their exceptional research papers published in the journal.
The award, also known as the Parmley Prize, recognizes remarkable first-author publications by trainees in JACC. The award aims to elevate trainee-led research in JACC and put the spotlight on their contributions to cardiovascular science.
This year’s winners and their mentors are:
Aldostefano Porcari, PhD
National Amyloidosis Centre, Division of Medicine, University ...
Mass General Brigham researchers identify mutations that can lead to resistance to some chemotherapies
2025-03-28
Investigators at Mass General Brigham have uncovered how resistance to chemotherapies may occur in some cancers. Researchers focused on a pathway that harnesses reactive oxygen species (ROS) to kill cancer cells. The study found that mutations to VPS35, a key player in this pathway, can prevent chemotherapy-induced cell death. These results, published in Nature, could help pinpoint treatment-resistant tumors.
“ROS play an important role in healthy and diseased cells, but pathways that sense and control cellular ROS levels are not well understood,” said corresponding author Liron Bar-Peled, PhD, of the Krantz Family ...
JACC journals honor 10 young researchers
2025-03-28
The American College of Cardiology has recognized 10 young researchers with the Young Author Achievement Award, due to their outstanding research published in the JACC family of journals. All recipients will receive a commemorative plaque and be recognized during the American College of Cardiology’s Annual Scientific Session (ACC.25) in Chicago.
JACC’s Young Author Achievement Awards are awarded to researchers within the first five years of their training. Editorial boards for each JACC journal nominate winners chosen ...
Jefferson Lab Director Kimberly Sawyer named to CoVaBIZ Magazine’s 150 Most Influential People List
2025-03-28
NEWPORT NEWS, VA – The U.S. Department of Energy’s Thomas Jefferson National Accelerator Facility is making good waves in coastal Virginia, and now its director is being recognized for those positive impacts. CoVaBIZ has listed Jefferson Lab Director Kimberly Sawyer in its 2025 list of the 150 most influential people in coastal Virginia.
“It is an honor to be named to this list, and it reflects well on the positive economic, research and education impacts that Jefferson Lab has on our region,” said Sawyer, who took the helm at Jefferson Lab in July 2024. “We are proud to advance our research mission as Virginia’s national lab and ...
The world according to mosquitoes: USU ecologists lead AI-based effort to identify disease vectors
2025-03-28
LOGAN, UTAH, USA — Morphology is the study of the form and structure of organisms, including their physical characteristics such as shape, size and arrangement of parts. Morphology is key to taxonomy, the science of classifying organisms, as scientists use morphology to identify and study species, as well as to explore evolutionary processes.
Identifying species is challenging — even with large animals and plants, says Utah State University ecologist Norah Saarman.
“Trying to visually identify different species in small organisms such as mosquitoes is extremely difficult, as the species are very similar ...
Drexel researchers develop new DNA test for personalized treatment of bacterial vaginosis
2025-03-28
Roughly one out of three women ages 14-49 in the United States develop a vaginal bacterial imbalance known as bacterial vaginosis (BV) during their lifetime. BV is characterized by unpleasant odors, and potentially painful side effects, as well as the risk of associated health issues later in life. More than half of the patients who seek medical care do not respond to the first-line treatment, the antibiotic metronidazole, leading to recurrence.
Now Drexel researchers have developed ...
Keith T. Flaherty, MD, FAACR, elected as American Association for Cancer Research President-Elect for 2025-2026
2025-03-28
PHILADELPHIA – The members of the American Association for Cancer Research (AACR) have elected Keith T. Flaherty, MD, Fellow of the AACR Academy, as the AACR President-Elect for 2025-2026. Flaherty will become President-Elect on Monday, April 28, during the AACR’s Annual Business Meeting of Members at the AACR Annual Meeting 2025 in Chicago, Illinois and will assume the Presidency in April 2026 at the AACR Annual Meeting in San Diego, California.
Flaherty is director of clinical cancer research and the Richard Saltonstall Endowed Chair in Oncology at Mass General Cancer Center, ...
Brownie points for ChatGPT’s food analysis skills
2025-03-28
URBANA, Ill. — AI is changing the way we work, create, and share information — but brownies? A new study from the University of Illinois Urbana-Champaign explores how ChatGPT can be used in the sensory evaluation of foods, specifically brownies. The study offers insights that could streamline development of new products, and possibly enhance recipes moving forward.
But, why use AI for brownie tasting? Most people would gladly line up to sample chocolatey treats. However, in the food industry, sensory evaluation is an essential yet rigorous and costly process. Companies ...
The Giants Foundation provide 12 schools with CPR resources to improve cardiac emergency outcomes
2025-03-28
NEW JERSEY, March 27, 2025 — The American Heart Association and The Giants Foundation, the nonprofit organization of the New York Giants, gathered representatives from 12 local schools for cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED) training on March 20 at MetLife Stadium. According to American Heart Association data, nearly 9 out of 10 people who experience cardiac arrest outside of a hospital die, in part because they do not receive immediate CPR more than half of the time. CPR, especially if performed immediately, can double or triple a person’s chance of survival.
“Early recognition and action in a cardiac emergency ...
Why scientists are worried about weasels
2025-03-28
When monitoring the health of mammal populations, scientists often use camera traps to observe the animals in their habitats. But weasels are so sneaky they’re rarely caught on camera – leaving scientists with questions about this population of predators.
“We’re a little worried about the weasels,” says Roland Kays, a research professor at North Carolina State University and scientist at the N.C. Museum of Natural Sciences. “We don’t see them very often, but it’s ...
American College of Cardiology recognizes 21 Distinguished Award recipients
2025-03-28
The American College of Cardiology is proud to announce the recipients of the 2025 Distinguished Awards. The twenty-one recipients have made remarkable contributions to the cardiovascular professional, helping the ACC in its mission to transform cardiovascular care and improve heart health for all.
Awardees will be recognized during Convocation at the American College of Cardiology’s Annual Scientific Session (ACC.25) taking place March 29 – 31, 2025, in Chicago.
The 2025 Distinguished Award winners are:
2025 Bernadine Healy Leadership in Women’s Cardiovascular Disease
Malissa J. Wood, MD, FACC
2025 Distinguished Cardiovascular ...
American College of Cardiology recognizes three recipients of the Hani Najm Global Scholar Award Observership Program
2025-03-28
The American College of Cardiology will honor three early career cardiologists with the Hani Najm Global Scholar Award Observership Program at ACC's Annual Scientific Session (ACC.25), taking place March 29 – 31, 2025, in Chicago.
Established in 2020 at the Saudi Heart Association’s Annual Conference, the Hani Najm Global Award Observership Program encourages and fosters the sharing of knowledge between international cardiology professionals, specifically early career cardiologists in the Middle East and Africa. Through its Observership Program, recipients have the opportunity to ...
DNA helps electronics to leave flatland
2025-03-28
Researchers at Columbia Engineering have for the first time used DNA to help create 3D electronically operational devices with nanometer-size features.
"Going from 2D to 3D can dramatically increase the density and computing power of electronics," said corresponding author Oleg Gang, professor of chemical engineering and of applied physics and materials science at Columbia Engineering and leader of the Center for Functional Nanomaterials' Soft and Bio Nanomaterials Group at Brookhaven National Laboratory.
The new manufacturing technique could also contribute to the ongoing effort ...
Studying cardiac cells in space to repair heart damage on Earth
2025-03-28
KENNEDY SPACE CENTER (FL), March 28, 2025 – Heart disease remains the leading cause of death in the United States, accounting for one in five deaths. The inability of damaged heart muscle tissue to regenerate makes heart disease difficult to treat, and end-stage heart failure patients have no choice but to join a long list of people waiting for a heart transplant. Researchers from Emory University are working to provide another option for such patients. To do this, the team took their research to a laboratory unlike any on Earth—the International Space Station (ISSInternational Space Station).
Chunhui ...
Studies evaluate the health effects of bioactive compounds obtained from plants
2025-03-28
Fruits and plant extracts contain bioactive compounds that can help treat or prevent diseases. To characterize and understand their mechanism of action, researchers from universities and research institutions in Brazil and Germany have conducted independent but complementary studies.
Some of the results were presented at a lecture session on the future of food and nutrition research on March 25th during FAPESP Week Germany at the Free University of Berlin.
According to Ulrich Dobrindt, a professor at the University of Munich in Germany, medicinal plants contain different types of phytochemicals (natural ...
Howard University physicist revisits the computational limits of life and Schrödinger’s essential question in the era of quantum computing
2025-03-28
WASHINGTON, DC – (March 28, 2025) More than 80 years ago, Erwin Schrödinger, a theoretical physicist steeped in the philosophy of Schopenhauer and the Upanishads, delivered a series of public lectures at Trinity College, Dublin, which eventually came to be published in 1944 under the title What is Life?
Now, in the 2025 International Year of Quantum Science and Technology, Philip Kurian, a theoretical physicist and founding director of the Quantum Biology Laboratory (QBL) at Howard University in Washington, D.C., has used the laws of quantum mechanics, which Schrödinger postulated, and the QBL’s discovery of cytoskeletal ...
Navigating a US bioscience career despite anticipated cuts in funding for biomedicine
2025-03-28
Many young and midcareer scientists in the U.S. are understandably anxious about potential cuts to government funding and the rise of junk science. Although your future in biomedicine may not be what you originally planned, it might actually become more interesting and filled with new possibilities and opportunities for innovation. Don’t think of this time to hunker down and disappear. Do the opposite with the understanding that you are more powerful and brilliant than you may realize.
In your coverage, please use this URL to provide access to ...
How the failure of two dams amplified the Derna Flood tragedy
2025-03-28
A new study reveals that the devastating 2023 flood in Derna, Libya, was not merely the result of extreme rainfall but was drastically intensified by a major design shortcoming and its resulting collapse of two embankment dams. Through advanced hydrological modeling and satellite data analysis, researchers found that while Storm Daniel brought heavy rainfall, the catastrophe stemmed from dam failures and flawed risk assessment and communication—amplifying the destruction nearly twentyfold. The findings highlight the urgent need for improved flood mitigation strategies, especially in dryland regions where high uncertainty ...
Oral contraceptives and smoking impact steroid hormone levels in healthy adults
2025-03-28
Steroid hormone levels in healthy adults are influenced by oral contraceptives and smoking, as well as other lifestyle choices and factors such as biological sex and age, according to new research that has just been published in leading international journal Science Advances.
The objective of the research was to expand knowledge and understanding of steroid hormone levels, including corticoids and sex hormones, in healthy women and men over a broad age range. This is the first study to analyse such a large number of hormones in nearly 1,000 healthy people, filling a ...
C-Path’s predictive safety testing consortium advances a transformative test to detect drug induced liver injury
2025-03-28
TUCSON, Ariz., March 27, 2025 – Researchers from Critical Path Institute’s® (C-Path) Predictive Safety Testing Consortium have proposed glutamate dehydrogenase (GLDH) as a more liver-specific biomarker for detecting liver injury, supporting clearer decision-making. Currently, alanine aminotransferase and aspartate aminotransferase (ALT and AST) are considered the “gold standard” biomarkers in clinical practice and drug development. However, these biomarkers are not specific to the liver and can reflect changes in other tissues, which may lead to unclear diagnoses, particularly in individuals with muscle conditions ...
Green solvent innovation: high-speed doctor-blading boosts organic solar cell efficiency
2025-03-28
In a recent advancement, researchers have developed a high-speed doctor-blading technique that enhances the efficiency of organic solar cells (OSCs) while using eco-friendly, non-halogenated solvents. This innovative method not only addresses the environmental and scalability challenges of traditional solvents, such as chloroform, but also achieves impressive power conversion efficiencies (PCEs) of 18.20% and 17.36% with green solvents like o-xylene and toluene, respectively. With a module efficiency of 16.07%, this breakthrough sets the stage for more sustainable, ...
C-Path announces successful conclusion of the ECOA: getting better together initiative
2025-03-28
TUCSON, Ariz., March 26, 2025 – Critical Path Institute® (C-Path)Patient-Reported Outcome (PRO) Consortium and Electronic Clinical Outcome Assessment (eCOA) Consortium are pleased to announce the successful conclusion of the eCOA: Getting Better Together Initiative. This initiative, driven by a shared commitment to advancing patient-focused drug development, has culminated in meaningful, lasting changes that will benefit all stakeholders across the eCOA ecosystem.
Beginning in 2019, this C-Path-led collaborative, pre-competitive initiative brought ...
Brain channels ‘stopped in time’ reveal chemical flow that enables learning and thinking
2025-03-28
FOR IMMEDIATE RELEASE
In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most common signaling molecules, glutamate, opens a channel and allows a flood of charged particles to enter. The finding, which resulted from a study led by Johns Hopkins Medicine researchers, could advance the development of new drugs that block or open such signaling channels to treat conditions as varied as epilepsy and some intellectual disorders.
A report on the experiments, funded by the National ...
PET imaging confirms direct involvement of dopamine in cognitive flexibility
2025-03-28
Reston, VA (March 16, 2025)—For the first time, scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility, according to new research published in the March issue of The Journal of Nuclear Medicine. PET imaging shows that the brain increases dopamine production when completing cognitively demanding tasks, and that the more dopamine released, the more efficiently the tasks are completed. Armed with this information, physicians may soon be able to develop more precise treatment strategies for neurological and psychiatric disorders.
Cognitive flexibility is the ability to adapt one’s thinking and behavior appropriately to ...
Understanding the immune response to a persistent pathogen
2025-03-28
Most humans have long-lived infections in various tissues—including in the nervous system—that typically do not result in disease. The microbes associated with these infections enter a latent stage during which they quietly hide in cells, playing the long game to evade capture and ensure their own survival. But a lack of natural models to study these quiescent stages has led to gaps in scientists’ understanding of how latency contributes to pathogen persistence and whether these stages can be targeted by the immune system.
Now, a team led by University of Pennsylvania School of Veterinary Medicine researchers ...
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