The International Society for Stem Cell Research (ISSCR) is proud to announce the release of Best Practices for the Development of Pluripotent Stem Cell-Derived Cellular Therapies, a comprehensive, interactive new resource designed to accelerate the translation of human pluripotent stem cell (PSC)-derived therapies into clinical trials and commercial use. Developed by leading international experts in cell therapy, this groundbreaking document outlines the key principles and decision points required to develop safe, effective, and regulatory compliant PSC-derived products. Organized into seven sections, the guidance offers jurisdictionally neutral ...

Using millions of microscope images magnified up to 130,000 times, researchers from Radboud university medical center and Toronto have unraveled the structure of two key proteins in the malaria parasite. With this knowledge, scientists are developing new vaccines that block the transmission of parasites via mosquitoes. Malaria, a parasitic infectious disease, has existed since the time of the ancient Egyptians and still threatens nearly half of the world’s population. In recent years, two malaria vaccines have become available that protect against infection, but they ...

About The Study: The results of this study of World Trade Center (WTC) responders suggests that, when compared with the lowest reported exposure levels, a higher level of reported exposure to more particulate dust or debris was significantly associated with an increased incidence of lung cancer. Future studies may investigate specific WTC exposures and histologic changes and clarify the role of WTC exposure for prognosis.  Corresponding Author: To contact the corresponding author, Sean ...

This roundup highlights new insights into why acute myeloid leukemia resists treatment, racial disparities in triple-negative breast cancer, a potential strategy to make CAR T therapies stronger, early human trial results for an investigational new treatment for glioblastoma and a new approach to fighting pancreatic cancer — with a virus.  To learn more about research at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation’s top cancer centers ...

Beyond spirited dinner party debate, establishing which creatures have consciousness matters in terms of animal welfare and conservation policy. A Michigan State University philosophy scholar has added clarity to a messy philosophical debate. In this month’s journal Biology & Philosophy, PhD candidate Jonah Branding contributes a decision tree that can be applied to questions such as, do fish feel pain when they’re on a hook? Does an ant feel alarm when protecting its colony? Do banana slugs feel anything when they eat dead leaves on the forest floor? Or are these simpler organisms more like stimulus-response machines, which don’t have any mental experience? “There ...

Background and objectives MD-1 is a time-tested polyherbal diabetes supplement in Tamil Nadu, India. It is composed of dried powdered herbs: Phyllanthus amarus Schum. & Thonn, Tinospora cordifolia (Willd.) Miers ex Hook. F. & Thoms, Emblica officinalis Gaertn., Eugenia jambolana Lam., Gymnema sylvestre R. Br. Ex, and Cassia auriculata Linn. This study aimed to investigate the in vivo effects of MD-1 in high-fat diet (HFD)-induced diabetes mellitus in C57BL/6J mice. Methods After 10 weeks of HFD induction, diabetic mice (n = 60) ...

About The Study: Although the incidence of new-onset atrial fibrillation (AF) after coronary artery bypass grafting (CABG) in this study was higher than previously reported, the AF burden in these patients was very low, especially after 30 days. The very low AF burden questions the current guideline recommendations that long-term oral anticoagulation should be considered in patients with new-onset AF after CABG. Corresponding Author: To contact the corresponding author, Florian Herrmann, MD, email florian.herrmann@med.uni-muenchen.de. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2025.14891) Editor’s ...

About The Study: In this nationwide analysis, emergency Medicaid accounted for only a small fraction of total Medicaid expenditures. Although states with larger undocumented populations spent approximately 15 times more per capita, emergency Medicaid still constituted less than 1% of overall Medicaid spending even in states with large undocumented populations, posing a limited fiscal burden on Medicaid. These results suggest that cuts to emergency Medicaid will produce minimal overall cost savings and will disproportionately harm states with large undocumented populations. Corresponding Author: To ...

What it's about: Raw milk (untreated milk) enjoys a certain popularity, but poses health risks. To avoid food poisoning, it should be boiled before drinking. But how well is raw milk actually known among the population? How do people perceive its health risk? Two-thirds of those surveyed had already heard of raw milk. Only ten percent expressed concern, making raw milk the topic of least concern of the risks surveyed. This is according to the BfR Consumer Monitor, a regularly conducted representative survey by the German Federal Institute for Risk Assessment (BfR). “The health risks of raw milk ...

“This study was designed to investigate the effect of long-term social housing on cognitive decline and neuron ensemble activity dynamics in old age.” BUFFALO, NY — October 9, 2025 — A new research paper was published in Volume 17, Issue 9 of Aging-US on August 22, 2025, titled, “The impact of long-term social housing on biconditional association task performance and neuron ensembles in the anterior cingulate cortex and the hippocampal CA3 region of aged rats.” The research team led by Anne M. Dankert from Providence College and University of North Carolina, Chapel Hill, ...

A world-first discovery of binary stars could be the first step in building a more complete picture of how our galaxy formed, according to astronomers from The Australian National University (ANU).    The discovery is part of an ambitious 10-year program to scan the entire southern sky every few nights.   The study's lead author, ANU researcher Dr Giacomo Cordoni, said the Legacy Survey of Space and Time (LSST) will build an extraordinary “movie of the universe".   “This survey—run from ...

Poor blood sugar control in adolescence increases the risk of painful future complications for people with type 1 diabetes, research co-led by University of Michigan suggests. The study, which followed participants for over 30 years, highlights how children diagnosed with type 1 diabetes at a young age have trouble controlling their blood sugar as teens. Investigators found that children who had poor glycemic control — meaning, higher-than-average blood sugar levels — during adolescence were ...

WASHINGTON—A popular class of therapies for treating diabetes and obesity may also have the potential to treat alcohol and drug addiction, according to a new paper published in the Journal of the Endocrine Society. The therapies, known as Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs), present an encouraging approach to treating alcohol and other substance use disorders. “Early research in both animals and humans suggests that these treatments may help reduce alcohol and other substance use,” ...

Watching short inspirational videos may be just as effective at reducing stress as meditation, according to research published by the American Psychological Association. Stress has arguably reached epidemic levels in the U.S. According to the APA’s Stress in America survey, Americans say they’re feeling more anxious than in previous years, with a majority of people 18-44 saying they feel moderate to extreme stress daily.   “Though there are many effective ways to deal with stress, people often feel too busy or overwhelmed to enact these strategies,” ...

PLYMOUTH MEETING, PA [October 9, 2025] — New research published online in JNCCN—Journal of the National Comprehensive Cancer Network finds that people with cancer who quit smoking had a much lower risk of dying within two years compared to those who kept smoking. The researchers followed more than 13,000 individuals with cancer, tracking whether they quit smoking in the first six months after being seen in clinic. The survival benefit was seen across all cancer types and stages, including stages III and IV, where treatment may be less curative. Despite these benefits, only about 1 in 5 smokers quit within six months of their visit. The Cancer ...

Washington, October 9, 2025—A new large-scale analysis of existing research finds that school-provided social and emotional learning (SEL) programs improve students’ academic achievement in addition to their social and emotional development. The study appears today in Review of Educational Research, a journal of the American Educational Research Association. The study was authored by Cheyeon Ha of the University of Southern California, and Michael F. McCarthy, Michael J. Strambler, and Christina Cipriano of the Education Collaboratory at Yale. In a systematic analysis of 40 studies involving more than 33,700 students in grades 1 through 12, researchers led ...

Around 25% of people with cancer in the U.S. are active smokers when they are diagnosed, and studies have found that many of them continue to smoke during treatment. This may be due in part to a common misconception — even among some doctors — that quitting won’t help much if a person already has cancer, particularly if it’s at an advanced stage. Now, a study led by Li-Shiun Chen, MD, a professor of psychiatry at Washington University School of Medicine in St. Louis, shows that kicking the habit after ...

Rockville, MD. (October 9, 2025) – In its mission to accelerate transformative cancer innovations and drive cures forward, the AIM-HI Accelerator Fund is pleased to announce the winners of the 2025 AIM-HI Venture Competition: ResNovas Therapeutics, co-founded by Nobel Laureate Carolyn Bertozzi, Ph.D., Michelle Arkin, Ph.D., CTO Ian Churcher, Ph.D., and CEO Gabriele Sulli, Ph.D.; and Chiara Biosciences, co-founded by National Academy of Inventors Fellow Francis Barany, Ph.D. and CEO Kirsten Flowers, MBA. The 2025 AIM-HI Venture Competition Committee reviewed more than 80 applications from early-stage oncology ...

Rockville, Md. - The American Society of Human Genetics (ASHG) 2025 Annual Meeting will take place October 14-18, 2025 at the Thomas M. Menino Convention & Exhibition Center in Boston, MA. Credentialed members of the press and media are eligible to request complimentary press access to attend the in-person event. The ASHG 2025 Annual Meeting highlights cutting edge research in genetics and genomics from scientists and clinicians from around the world. Abstracts ...

Adding genomic sequencing to newborn blood screening would detect hundreds of additional childhood conditions, providing much earlier diagnosis and treatment, according to a new study. A baby’s genome, which stays with them for life, could also be re-examined if a health issue arises during their lifetime. The study, led by Murdoch Children’s Research Institute (MCRI) and Victorian Clinical Genetics Services (VCGS), found genomic screening, a test that reveals a person’s entire genetic ...

Researchers explore the human immune system by looking at the active components, namely the various genes and cells involved. But there is a broad range of these, and observations necessarily produce vast amounts of data. For the first time, researchers including those from the University of Tokyo built a software tool which leverages artificial intelligence to not only offer a more consistent analysis of these cells at speed but also categorizes them and aims to spot novel patterns people have not yet seen. Our immune system is important — it’s impossible to imagine complex life existing without it. This ...

Lots of single-use water bottles made from poly(ethylene terephthalate) (PET) end up in landfills, but there’s a growing interest in upcycling them instead. Researchers in ACS’ Energy & Fuels report on new heat-based fabrication methods to transform PET into supercapacitor electrodes and separator films for upcycled energy storage devices. In demonstrations, an all-plastic supercapacitor made from discarded water bottles outperformed a similar design that used a traditional glass fiber separator. “PET ...

Food waste is more than just the starting material for compost. From dried-up beet pulp to millipede-digested coconut fibers, scientists are finding treasure in our trash. Four recent papers published in ACS journals detail how food waste contains sustainable solutions for farming and new sources of bioactive compounds for pharmaceuticals. Reporters can request free access to these papers by emailing newsroom@acs.org. Sugar by-product may “beet” wheat disease. Researchers report in ACS’ Journal of Agricultural and Food Chemistry that sugar beet pulp could help reduce agriculture’s reliance on synthetic pesticides. The pulp, about 80% of the beet’s ...

It is widely recognized that the Bank of Japan’s Exchange-Traded Fund (ETF) purchases had a substantial impact on stock prices. Market participants and media reports have often highlighted that the policy distorted market valuations. At the same time, they pointed out that ETF management appeared to accelerate stock lending activity as the number of ETFs held by the Bank of Japan increased over time. This pattern suggests that the stock market, particularly the lending market, has mechanisms that enhance market efficiency and counteract the effects of the Bank of Japan’s policy. Recently, a team of researchers from Japan, led by Dr. Junnosuke ...

Patents are valuable for the generation of novel ideas through technology opportunity discovery. In recent years, scientists have made several attempts to identify technology opportunities by determining vacancies in patent maps—visual representations of patent distribution in particular technological fields created using dimensionality reduction techniques. However, there is a major bottleneck in this approach: it is challenging to precisely define and interpret the technological content of these patent vacancies. In a breakthrough study, researchers from the Republic of Korea and the United States, led by Professor Hakyeon Lee of the Department ...