HAMMAMET, TUNISIA [November 4, 2025] — The National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers in the United States—collaborated with the African Cancer Coalition and the American Cancer Society to describe how cancer treatment guidelines have evolved across Sub-Saharan Africa in recent years, during the biannual African Organization for Research and Training in Cancer (AORTIC) gathering in Hammamet, Tunisia. As part of the event, the African Cancer Coalition, American Cancer Society, and NCCN are showcasing the transition from harmonized ...

DALLAS, Nov. 4, 2025 – As digital health technologies gain momentum,[1] research is finding that more people are open to artificial intelligence (AI) supported health interventions when those are backed by clinical expertise and rooted in evidence-based guidelines.[2] To harness this opportunity, the American Heart Association, a relentless force changing the future of health for everyone everywhere, launched its inaugural CarePlan Challenge this year to drive innovation and expand access to guideline-based cardiovascular care. The American Heart Association’s Center for Health Technology & Innovation invited developers, health technology innovators ...

The road to genocide doesn’t begin with bullets and mass graves, but with more subtle violations. Declining workers’ rights or compromises on the right to a fair trial may come first. Brutality by law enforcement and prison guards becomes widespread. The judiciary loses its independence from the executive branch. And then, more serious signs follow: Freedom of speech is restricted for a specific group of people, and then their right to assemble in public places. Members of this group may find themselves increasingly imprisoned for their beliefs, ...

Different species of spiders produce different silks that serve different purposes, from floating on air to cradling eggs. The triangle weaver spider, Hyptiotes cavatus, weaves and holds a three-sided web under tension, which it releases the moment prey flies into the web, quickly tangling the prey in the spring-loaded threads. Thus, the web can move much faster than any muscle in the spider’s body, illustrating how silk can amplify a spider’s abilities. Jessica Garb and colleagues sequenced the genome of ...

An analysis of brain scans from 572 people reveals that activity in brain regions linked to reward and social processing can predict how effective messages will be. Christin Scholz, Hang-Yee Chan, Emily Falk, and colleagues pooled data from 16 functional MRI studies to explore how the human brain responds to persuasive messages across various contexts, including public health campaigns, crowdfunding sites, movie trailers, and YouTube videos. Across these diverse settings, the researchers found that effective messages activated brain regions involved in anticipating and receiving rewards, ...

SEATTLE, WASH. — November 4, 2025 — The Allen Institute’s 2025 Next Generation Leaders (NGL) cohort features eight talented researchers exploring the frontiers of bioscience and pursuing insights into biology with the potential to advance human health. “We are so excited to welcome the newest cohort of Next Generation Leaders to the Allen Institute community. These exceptional early-career scientists are on a path to transform bioscience fields, and we look forward to being part of their journey,” said Julie Harris, Ph.D., vice president of the Allen Institute’s ...

The Australian Digital Inclusion Index has found almost half of Australians recently used generative AI tools, raising new opportunities and challenges for digital inclusion. Usage was highest among students, with 79% reporting recent use, while 69% of Aussies aged 18 to 34 have also engaged with GenAI.  Overall, 46% of Australians reported recently using GenAI. People living in remote areas were twice as likely to use AI chatbots for social connection or conversations than those in metropolitan areas. Australians who speak a language other than English at home were more likely ...

Ribonucleic acid (RNA) is one of life’s most versatile molecules, with roles going far beyond being a messenger of genetic code, as it is fundamentally involved in gene regulation, processing, and maintenance across all living systems. This versatility is deeply tied to RNA’s ability to adopt complex three-dimensional shapes, known as secondary and tertiary structures. With the global rise of RNA-based therapeutics, understanding and precisely predicting secondary and tertiary structures is essential to fully harness the RNA’s ...

Closing the skull safely and securely after surgery remains one of neurosurgery’s biggest challenges. Traditional fixation systems made from titanium or semi-absorbable polymers can interfere with brain imaging, degrade unevenly, or remain in the body long after healing. These drawbacks can slow down recovery, cause discomfort, and increase the risk of complications. To address these issues, a team led by Dr. Siyi Wanggou and Professor Xuejun Li from the Department of Neurosurgery, Xiangya Hospital, Central South University, China, collaborated with MedArt Technology Co., Ltd., China, to develop a fully degradable cranial flap fixation system made from high-purity poly-L-lactic ...

Key findings Enhanced prediction capability: Machine learning-based system matches and in some cases outperforms traditional forecasting systems, with particular improvements in northern Europe where conventional methods struggle Critical timing insights: Greatest forecast skill comes from atmospheric predictors 4-7 weeks before summer (mid-March), providing optimal lead time for preparation measures Lives and livelihoods at stake: Early warning capability could help the agricultural industry and health services implement effective strategies against heatwaves, which cause increased mortality and economic ...

WASHINGTON (Nov. 4, 2025)--Imagine early humans meticulously crafting stone tools for nearly 300,000 years, all while contending with recurring wildfires, droughts, and dramatic environmental shifts. A recent study, published in Nature Communications, brought to light remarkable evidence of enduring technological tradition from Kenya’s Turkana Basin. An international multi-center research team has uncovered at the Namorotukunan Site one of the oldest and longest intervals of early Oldowan stone tools yet discovered, dating from approximately 2.75 ...

A new study published in Environmental Research Letters reveals that even advanced climate intervention strategies may not be enough to secure the future of wine grapes, coffee and cacao. These crops are vital to many economies and provide livelihoods for farmers worldwide. However, they are increasingly vulnerable to the effects of climate change. Rising temperatures and changing rainfall patterns cause big variations in crop yields from year to year, meaning that farmers cannot rely on the stability of their harvest, and their produce is at risk. The researchers ...

Embargo 4 November 10:00 UK / 05:00 US Eastern Times Peer-reviewed / Experimental / Bacteria   ADVANCED DISEASE MODELLING SHOWS SOME GUT BACTERIA CAN SPREAD AS RAPIDLY AS VIRUSES Escherichia coli (E. coli), a type of bacteria commonly found in the human gut, could spread as quickly as swine flu, new research suggests. For the first time, researchers at the Wellcome Sanger Institute, the University of Oslo, the University of Helsinki, Aalto University in Finland, and their collaborators are able to predict the rate at which one person could transmit ...

Beyond the disruption to Ukraine’s food exports, the war is jeopardising the country’s long-term ability to remain the ‘breadbasket of Europe’, because its soils are gradually losing vital crop nutrients. That is the warning issued by researchers from the UK, Ukraine and the Netherlands who say more nitrogen, phosphorus and potassium* are now being removed from soils via harvested crops than added back in. This is due to reduced access to fertilisers during the war and inefficient farming practices. Military activity has also exacerbated existing degradation and erosion ...

In urban environments, competing hornet species coexist by specializing on different prey species. The Kobe University study was made possible by pioneering DNA analysis of hornet larvae's gut contents and shows that cities are fascinating model systems for how predatory species adapt to environmental stress. City gangs brutally illustrate a principle that is a staple in ecological theory, the “competitive exclusion principle”: Two species competing for the same limited resource cannot coexist. Nature seems to find more peaceful solutions. “The yellow-vented hornet and the Japanese yellow hornet are both considered urban adapters with nesting sites and activity ...

Contrary to previous research, transgender women who use the hormone oestradiol for their transition do not have an increased risk of heart attack and stroke compared to men in the general Dutch population. This is shown by a large-scale study from Amsterdam UMC, with data from more than 4,000 transgender individuals, published today in the European Heart Journal. The researchers suspect that the hormone treatment transgender women receive has a protective effect on the heart and blood vessels. In transgender people, the sex assigned at birth does not match their experienced gender identity. Many of them therefore choose hormone treatment to develop ...

A new paper in Environmental Toxicology and Chemistry, published by Oxford University Press, finds high qualities of toxic “forever” chemicals in sea otters recovered off the Pacific Ocean. Per- and polyfluoroalkyl substances, so called “Forever Chemicals,” are used in the lining of food packaging, non-stick cookware, waterproof and stainproof textiles, cosmetics, firefighting foams, and electronics. These chemicals, which bioactively bind to proteins within an organism, can ...

BIRMINGHAM, Alabama, USA, 4 November 2025 — What if the brain’s response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome’s architecture. Stress, the genome, and a hidden layer of regulation. The study, led by Professor Yogesh Dwivedi, Distinguished Professor and Elesabeth Ridgely Shook Endowed Chair in the Department of Psychiatry and Behavioral ...

New York, New York, 4 November 2025 – A comprehensive review published today in Brain Medicine illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep disorders. The research, led by Professor Lin Lu from Peking University Sixth Hospital and an international team of collaborators spanning institutions in China and the United States, synthesizes current insights into how the trillions of bacteria residing in our digestive system ...

A research team led by Dr. Kee Young Koo from the Hydrogen Research Department at the Korea Institute of Energy Research (President Yi Chang-Keun, hereafter referred to as KIER) has developed a world-class catalyst for the reverse water–gas shift reaction, transforming carbon dioxide, a major greenhouse gas, into a key building block for eco-friendly fuels. The reverse water–gas shift (RWGS) reaction is a technology that converts carbon dioxide (CO₂) into carbon monoxide (CO) and water (H₂O) by reacting it with hydrogen ...

EMBARGOED UNTIL TUESDAY, NOVEMBER 4, 2025 AT 12:01 AM ET  When Bathroom Breaks Rule Your Day A new survey reveals men would rather sit in traffic than talk about prostate health ORLANDO, FL — A new survey from Orlando Health reveals that over one-third of men (38%) would rather endure stressful situations, such as watching their team lose a big game or being stuck in traffic, than discuss their prostate health. This widespread reluctance to address a common health issue often leads to delayed diagnosis and treatment for conditions like an enlarged prostate. "The prostate is a gland that wraps around the urethra, and as we get older, our prostates tend ...

With global teacher shortages at an all-time high, retaining and recruiting teachers to the education sector is critical. Yet with fragmented support and inconsistent induction processes, nearly a fifth of early career teachers choose to leave within five years.   Education experts at the University of South Australia say that to address teacher shortages, Australia must develop stronger government policies focused on the retention and career development of early career teachers, particularly those in casual ...

Generative artificial intelligence (GenAI) has had a transformative impact on business, enabling the automation of routine tasks, freeing up employees to focus on more strategic and creative work, while also reducing costs and accelerating time to market.  However, new research from Edith Cowan University (ECU) published in the International Journal of Information Management and funded by the SBL Business Intelligence Research group, has highlighted some of the issues that could be hindering the adoption of these emerging technologies.     GenAI uses ...

With much of the world’s coral turning a ghostly white, UC Riverside scientists have launched a $1.1 million project to uncover how reefs regain life-giving algae after suffering from heat stress.  Bleaching occurs when stressed corals lose the algae living in their tissues. Without them, coral turns pale and begins to starve. If algae don’t return within a few weeks, the sickly coral dies, leaving behind a white skeleton that can no longer support the marine life that once depended ...

Background Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling pathways, including NF-κB, JAK/STAT, TLR, MAPK, HIF-1α, and Nrf2/Keap1, which collectively regulate immune activation, inflammation, and cellular metabolism. Mitochondrial dysfunction and metabolic reprogramming further contribute to its pathogenesis by impairing energy production and immune cell function. Conventional treatments, primarily reliant on antibiotics and early goal-directed therapy, often ...