One sleepless night can rapidly reverse depression for several days
All-nighters can cause giddy and slap-happy feelings This effect is caused by increased dopamine release in distributed brain regions This dopamine signal also enhances plasticity in the neuronal connections, causing a potent antidepressant effect that lasts for days Study suggests that prefrontal cortex and its dopamine inputs are key for rapid plasticity and antidepressant effects after brief sleep loss EVANSTON, Ill. — Most people who have pulled an all-nighter are all too familiar with that “tired and wired” ...
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