Researchers from Queen Mary University of London have identified a protein that could be used to aid in the diagnosis of pancreatic cancer. Findings from the new study suggest that a protein called pentraxin 3 (PTX3) may be a specific diagnostic biomarker - or biological measure - for pancreatic cancer, with the ability to differentiate pancreatic cancer from other non-cancerous conditions of the pancreas. The research was published today in npj Precision Oncology, and primarily funded by the Pancreatic Cancer Research Fund, Barts Charity and Cancer Research UK. PTX3 levels elevated in patients with pancreatic ...

This press release is in support of a presentation by Dr Maria Cerrillo Martinez presented online at the 37th Annual Meeting of ESHRE. 29 June 2021: Fertility patients who have a poor response to ovarian stimulation represent a stubborn challenge in IVF. Few eggs are collected, success rates are low, and several treatments are usually needed to achieve pregnancy (if at all). Clinical guidelines indicate that increasing the drug dose for stimulation or applying any of several adjunct therapies are of little benefit. Now, however, a study assessing two cycles of ovarian stimulation and two egg collections in the same menstrual cycle may yet provide ...

This press release is in support of a presentation by Dr Gulam Bahadur presented online at the 37th Annual Meeting of ESHRE. 29 June 2020: Studies indicate that the optimal and safe number of oocytes needed for achieving an ongoing pregnancy is between six and 15. However, the use of egg freezing, frozen embryo replacement (FER) cycles and aggressive stimulation regimes has increased this number in order to boost success rates in older women and in poor responders who produce fewer eggs. What is not known is the impact of numbers of eggs retrieved and of over-stimulation practices on the health of patients, and on their emotional and financial well-being. Now, a retrospective observational ...

After centuries of human impact on the world's ecosystems, a new study from Flinders University details an example of how a common native bee species has flourished since the very first land clearances by humans on Fiji. In a new paper in Molecular Ecology (DOI: 10.1111/mec.16034), research led by Flinders University explores a link between the expansion of Homalictus fijiensis, a common bee in the lowlands of Fiji, which has increased its spread on the main island Viti Levu alongside advancing land clearance and the introduction of new plants and weeds to the environment. "Earlier research connected the relatively recent population expansion to warming climates, ...

What is unique about the study is the combination of interviews with current and former people in prison, custodial professionals, and healthcare providers to identify and understand barriers in delivering high-quality healthcare and support to those in custody. In addition, researchers gathered data on the number, types and stages of cancers diagnosed in patients within prisons. Moving forward, the researchers believe that findings from this study will help inform prison cancer care policy and develop priorities for improving it within the prison system. The research was funded by the National Institute for Health Research (NIHR), the research partner of the NHS, public health and social ...

Arlington, Va., June 29, 2021 - In the midst of the COVID-19 pandemic, infection preventionists at two Southern California hospitals took extreme measures to stop the spread of a deadly fungus that has emerged in the U.S. and around the world. The two will detail their proactive responses in oral presentations today at the Association for Professionals in Infection Control and Epidemiology's (APIC's), 48th Annual Conference. In separate responses, Scripps Memorial in La Jolla and UCLA Health in Los Angeles isolated suspected or confirmed patients, worked closely with public health departments and information technology and lab teams at their facilities, and implemented aggressive measures ...

The devastating 2012 - 2016 drought in California triggered widespread tree cover loss and die-offs of a variety of species in the region. A new study in the open access journal Frontiers in Climate is the first to show that California's iconic blue oak (Quercus douglasii) woodlands have also decreased by more than 1,200 km2. By another metric, which reflects the altered or deteriorating condition of the tree cover, the blue oak range has lost over 600 km2 in addition. These findings highlight the need to raise awareness about the vulnerability of these ecosystems and to adapt conservation strategies to increasing climate extremes. "Our ...

Black men most likely to benefit from advanced prostate cancer therapies are 11 percent less likely to get them than non-Black men. This happens despite apparent equal opportunities in obtaining health care services, a new study in American veterans shows. Publishing in the journal Cancer online June 29, the study showed that Black male veterans were slightly (5 percent) more likely to receive radiation or surgery for prostate cancer than non-Black men and that veterans of all races likely to benefit from such definitive therapy were also 40 percent more likely to get it compared to those who did not need it. Led by researchers from NYU Langone Health and Perlmutter Cancer Center, the new analysis showed ...

A new paper in JNCI Cancer Spectrum, published by Oxford University Press, indicates that many survivors of adolescent and young adult cancers hesitate to obtain COVID-19 vaccinations. As of March 2021, there were over 33 million cases and 580,000 deaths from COVID in the United States. Vaccines offer the best hope to control the spread of COVID-19. Some 20%-40% of the US population, however, is hesitant to obtain COVID-19 vaccination. Cancer survivors often have weakened immune systems and are more likely to develop severe respiratory infections, making them particularly vulnerable to the threat of COVID-19. National organizations recommend strongly ...

According to the World Health Organization, about 785 million people around the world lack a clean source of drinking water. Despite the vast amount of water on Earth, most of it is seawater and freshwater accounts for only about 2.5% of the total. One of the ways to provide clean drinking water is to desalinate seawater. The Korea Institute of Civil Engineering and Building Technology (KICT) has announced the development of a stable performance electrospun nanofiber membrane to turn seawater into drinking water by membrane distillation process. Membrane wetting is the most challenging ...

CORVALLIS, Ore. - Research by a graduate student in Oregon State University's College of Science has upended the conventional wisdom that for a century has incorrectly guided the study of a toad listed as endangered in part of its range. Anne Devan-Song used spotlighting - shining a light in a dark spot and looking for eye reflections - to find large numbers of the eastern spadefoot toad. The study illustrates how confirmation bias - a tendency to interpret new information as ratification of existing theories - can hamper discovery and the development of better ones. Her findings, which show that the toad spends much more time above ground than commonly believed, were published in the Journal ...

Chestnut Hill, Mass. (6/29/2021) -- A new, first-of-its-kind study led by researchers from Boston College has found that personal networks in India could play an important role in advancing the adoption of a cleaner cooking fuel, in this case liquefied petroleum gas, according to a report published in the journal Environmental Research Letters. "This is the first report in clean cooking research to show that just like with tobacco use, obesity, or physical activity -- where our networks play a role in shaping our behaviors and decisions -- we find that personal networks are also associated with what kinds of stoves rural poor use.," said study co-author ...

The tiny mouse embryo has a heart that beats. Its muscles, blood vessels, gut and nervous system are beginning to develop. But this embryo is unusual: It was made in a lab, out of mouse embryonic stem cells, and represents the most sophisticated in vitro (in a dish) model of a mammal ever so created. This new model, developed at the University of Virginia School of Medicine by Christine and Bernard Thisse, is a major step forward in scientists' efforts to mimic the natural development of a mammal by using stem cells. Its existence is a wonder that will help scientists understand mammalian development, battle diseases, create new drugs and, eventually, grow tissues and organs for people in need of transplants. "We found a way to instruct aggregates of stem cells to initiate ...

Immunologists at McMaster University have discovered a previously unknown mechanism which acts like a spider web, trapping and killing pathogens such as influenza or SARS-CoV-2, the virus responsible for COVID-19. The researchers have found that neutrophils, the most abundant white blood cells in the human body, explode when they bind to such pathogens coated in antibodies and release DNA outside of the cell, creating a sticky tangle which acts as a trap. The findings, published online in the Proceedings of the National Academy of Science, are significant because little is understood about how antibodies neutralize viruses in the respiratory tract. The discovery has ...

One of the key mutations seen in the 'Alpha variant' of SARS-CoV-2 - the deletion of two amino acids, H69/V70 - enables the virus to overcome chinks in its armour as it evolves, say an international team of scientists. SARS-CoV-2 is a coronavirus, so named because spike proteins on its surface give it the appearance of a crown ('corona'). The spike proteins bind to ACE2, a protein receptor found on the surface of cells in our body. Both the spike protein and ACE2 are then cleaved, allowing genetic material from the virus to enter the host cell. The virus manipulates the host cell's machinery to allow the virus to replicate and spread. As SARS-CoV-2 ...

A conclusive narrative review has found physical punishment of children is not effective in preventing child behavior problems or promoting positive outcomes and instead predicts increases in behavior problems and other poor outcomes over time. The study by an international group of scientists including a researcher from The University of Texas at Austin was published today in The Lancet. Caregivers in many parts of the world use physical punishment as a response to children's perceived misbehavior: 63% of children between the ages of 2 and 4 worldwide - approximately 250 million children - are regularly subjected ...

Phase 1/2 clinical trial of CoronaVac in 550 children and adolescents aged 3-17 years in China suggests two doses of the vaccine are safe and generate a strong antibody response. First published data on safety and immune response generated by a COVID-19 vaccine in children as young as 3-years-old supports use of CoronaVac - which was recently approved for emergency use in China among children over 3-years-old - in further studies to inform immunisation strategies. Two doses of CoronaVac are safe and provoke a strong antibody response among children and adolescents ...

In first-of-its kind research led by a University of Massachusetts Amherst psychotherapy researcher, mental health care patients matched with therapists who had a strong track record of treating the patients' primary concerns had better results than patients who were not so matched. In addition, this "match effect" was even more beneficial and pronounced for patients with more severe problems and for those who identified as racial or ethnic minorities. The findings are published in JAMA Psychiatry and the Journal of Consulting and Clinical Psychology. "One of the things we've been learning in our field ...

PULLMAN, Wash. - A research team led by Washington State University has created a computer model to understand how plants store energy in the thylakoid membrane, a key structure to photosynthesis in plant leaves. The team confirmed the accuracy of the mathematical model with lab experiments. Their work was recently published in the journal Nature Plants. "We provided an important piece to the overall puzzle of plant metabolism," said Helmut Kirchhoff, a professor in WSU's Institute of Biological Chemistry and leader of the team who made this discovery. "If we integrate our model into the bigger picture, it may provide a good path for how to improve plants for ...

Two recent collaborative publications by CU Cancer Center members provide insights into how chronic inflammation can serve as a key factor in the development of leukemia and other blood cancers. Eric Pietras, PhD, CU Cancer Center member and assistant professor in the CU School of Medicine Division of Hematology, and James DeGregori, PhD, deputy director of the CU Cancer Center and professor in the Department of Biochemistry and Molecular Genetics, were corresponding authors on both papers. Both papers provide support for the theory of adaptive oncogenesis, which was developed by DeGregori. The theory stipulates that chronic inflammation (such ...

AMES, Iowa - During the course of a criminal investigation, it is common for investigators to interview individuals who are exhausted and have had little sleep. While unavoidable in some cases, a new Iowa State University study found sleep disruption or deprivation may limit the amount of information provided during an interview. The study, published in the academic journal SLEEP, is one of the first to look at how sleep affects behavior during interrogations or interviews. Zlatan Krizan, an ISU professor of psychology, says while beliefs about the impact of sleep on interrogation subjects have existed for decades, he and co-authors, ISU professor Christian Meissner and graduate student Anthony Miller, found little direct scientific evidence related to its effectiveness. Krizan ...

A new national study finds that children in the United States with greater screen time usage at ages 9-10 are more likely to gain weight one year later. The study, publishing in Pediatric Obesity on June 28, found that each additional hour spent on virtually all forms of screen time was associated with a higher body mass index (BMI) one year later. In particular, researchers found that each extra hour spent watching or streaming television, YouTube videos, video games, video chat, and texting led to a higher risk of weight gain one year later. At the start of the study, 33.7% of children were considered overweight ...

Scientists isolated a molecule, extracted from the leaves of the European chestnut tree, with the power to neutralize dangerous, drug-resistant staph bacteria. Frontiers in Pharmacology published the finding, led by scientists at Emory University. The researchers dubbed the molecule Castaneroxy A, after the genus of the European chestnut, Castanea. The use of chestnut leaves in traditional folk remedies in rural Italy inspired the research. "We were able to isolate this molecule, new to science, that occurs only in very tiny quantities in the chestnut leaves," says Cassandra Quave, senior author of the paper and associate professor in Emory's Center for the Study of Human Health and the School of Medicine's ...

COLUMBUS, Ohio -- Mountaintop glacier ice in the tropics of all four hemispheres covers significantly less area -- in one case as much as 93% less -- than it did just 50 years ago, a new study has found. The study, published online recently in the journal Global and Planetary Change, found that a glacier near Puncak Jaya, in Papua New Guinea, lost about 93% of its ice over a 38-year period from 1980 to 2018. Between 1986 and 2017 the area covered by glaciers on top of Kilimanjaro in Africa decreased by nearly 71%. The study is the first to combine NASA satellite imagery with data from ice cores drilled during field expeditions on tropical ...

Cunjiang Yu, Bill D. Cook Associate Professor of Mechanical Engineering at the University of Houston, is reporting the development of a camera with a curvy, adaptable imaging sensor that could improve image quality in endoscopes, night-vision goggles, artificial compound eyes and fish-eye cameras. "Existing curvy imagers are either flexible but not compatible with tunable focal surfaces, or stretchable but with low pixel density and pixel fill factors," reports Yu in Nature Electronics. "The new imager with kirigami design has a high pixel fill factor, before stretching, of 78% and can retain its optoelectronic performance while being biaxially stretched by 30%." Modern digital camera systems using conventional rigid, flat imaging sensors require ...