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Mental disorders and physical diseases co-occur in teenagers

2015-04-08
Every third teenager has suffered from one mental disorder and one physical disease. These co-occurrences come in specific associations: More often than average, depression occurs together with diseases of the digestive system, eating disorders with seizures and anxiety disorders together with arthritis, heart disease as well as diseases of the digestives system. These findings were reported by researchers from the University of Basel and the Ruhr-Universität Bochum. Their results based on data from 6,500 U.S. teenagers have been published in the scientific journal ...

Gene study helps explain Legionnaires' probe complications

2015-04-08
Genetic research helps to explain why tracing the source of an outbreak of Legionnaires' disease that claimed four lives has proven to be more complicated than scientists hoped. A DNA study of bacteria samples taken from patients infected during the 2012 outbreak in Edinburgh shows that it was caused by several subtypes of the bacteria. The unexpected discovery means that tracing the source of this - and any future outbreaks - will be challenging, researchers say. There were 92 confirmed or suspected cases during the outbreak in 2012 in addition to the four deaths. ...

Researchers urge stronger warning for indoor tanning risks

2015-04-08
AURORA, Colo. (April 8, 2015) - The U.S. Surgeon General should declare that indoor ultraviolet radiation tanning causes skin cancer, according to an article published today by the American Journal of Preventive Medicine. Robert P. Dellavalle, MD, PhD, MSPH, associate professor of dermatology at the University of Colorado School of Medicine on the Anschutz Medical Campus, is the corresponding author of the article, which says there is enough evidence for the Surgeon General to clearly state that use of indoor tanning beds causes skin cancer. Dellavalle and his co-authors ...

Overconfidence in new technologies can influence decision-making

2015-04-08
COLUMBIA, Mo. - Technological advances in recent decades have transformed most aspects of daily life, and technology now plays a major role in business and society. However, little is known about how perceptions of technology might influence decision-making. Now, University of Missouri researchers have shown that people tend to overestimate the likelihood of new technologies' success; this overconfidence can influence important decisions, such as investment choices. "Technology has advanced to the extent that people may not understand how a particular technology works, ...

Women, regardless of their backgrounds, seek help for the 'got to go' feeling

2015-04-08
(SACRAMENTO, Calif.) -- Regardless of their racial, ethnic, educational or socioeconomic background, women seek help for a frustrating -- and ubiquitous -- feature of becoming "a woman of a certain age:" the need be close to the women's room. Those are the findings of a large study by UC Davis of urinary incontinence in menopausal women, based on data from the Study of Women's Health Across the Nation (SWAN), a nine- year investigation of diverse menopausal women from six sites across the United States. The study is published online today in Obstetrics and Gynecology. The ...

Multi-organization call to action identifies and addresses safety concerns in labor

2015-04-08
WASHINGTON, April 8, 2015-- A healthcare, industry-first collaborative blueprint for labor and delivery safety, developed by four leading professional organizations in maternal health, calls for improving communication among clinicians, team leaders, administrators, health care providers, organizations, and patients to ensure fewer risks and better outcomes for mothers and babies. The four collaborating organizations are the American College of Nurse-Midwives; the American College of Obstetricians and Gynecologists; the Association of Women's Health, Obstetric and Neonatal ...

Hidden burden: Most people carry recessive disease mutations

2015-04-08
Humans carry an average of one to two mutations per person that can cause severe genetic disorders or prenatal death when two copies of the same mutation are inherited, according to estimates published today in the journal Genetics. The new numbers were made possible by a long-term collaboration between medical researchers and a unique community that has maintained detailed family histories for many generations. "These records offered a fantastic opportunity to estimate disease mutation carrier rates in a new way that disentangles the effects of genetic and socioeconomic ...

Brain scans reveal how people 'justify' killing

2015-04-08
A new study has thrown light on how people can become killers in certain situations, showing how brain activity varies according to whether or not killing is seen as justified. The study, led by Monash researcher Dr Pascal Molenberghs, School of Psychological Sciences, is published today in the journal Social Cognitive and Affective Neuroscience. Participants in the study played video games in which they imagined themselves to be shooting innocent civilians (unjustified violence) or enemy soldiers (justified violence). Their brain activity was recorded via functional ...

Plotting the elimination of dengue

2015-04-08
Dengue is a viral infection spread between humans by Aedes aegypti mosquitoes. Dengue causes flu-like symptoms, including intense headaches and joint pains. Published in the journal Science Translational Medicine, Professor Cameron Simmons, from the Department of Microbiology and Immunology at the University of Melbourne and the Peter Doherty Institute for Infection and Immunity, said that the discovery could lead to improved strategies to reduce the incidence of dengue. "We did a 'real world' experiment and allowed mosquitoes infected with Wolbachia and uninfected mosquitoes ...

Ironing out oxidative stress

2015-04-08
This news release is available in German. You're up in the mountains, the snow is blindingly white, and the sun is blazing down from the sky: ideal skiing conditions - but any skiers carrying the herpes virus might also have to reckon with the onset of cold sores after their day out. Increased exposure to UV radiation releases free radicals in the body. These put the body under oxidative stress, which weakens the immune system. And that in turn allows the herpes virus to prosper. Oxidative stress has become a major topic; not only is it implicated in many diseases, ...

Gay and lesbian job seekers face discrimination

2015-04-08
A new study shows that discrimination of gay and lesbian job seekers is commonplace within both private firms and the public sector in the UK. The research, carried out by Dr Nick Drydakis of Anglia Ruskin University and published by SAGE in the journal Human Relations, involved 144 young people - all first-time job seekers - making 11,098 applications. The study, the first of its kind ever conducted in the UK, found that gay applicants of both sexes are 5% less likely to be offered a job interview than heterosexual applicants with comparable skills and experience. The ...

Rates of ADHD appear to decrease at higher altitudes

2015-04-08
(SALT LAKE CITY)--Recent research has linked the thin air of higher elevations to increased rates of depression and suicide. But a new study shows there's also good news from up in the aspens and pines: The prevalence of attention deficit hyperactivity disorder (ADHD) decreases substantially as altitude increases. In Utah, for example, an analysis of information from two national health surveys correlated with the average state elevation of 6,100 feet showed that the rate of diagnosed ADHD cases is about 50 percent of states at sea level. In Salt Lake City, whose elevation ...

Nearly 1 in 10 adults have impulsive anger issues and access to guns

Nearly 1 in 10 adults have impulsive anger issues and access to guns
2015-04-08
DURHAM, N.C. - An estimated 9 percent of adults in the U.S. have a history of impulsive, angry behavior and have access to guns, according to a study published this month in Behavioral Sciences and the Law. The study also found that an estimated 1.5 percent of adults report impulsive anger and carry firearms outside their homes. Angry people with ready access to guns are typically young or middle-aged men, who at times lose their temper, smash and break things, or get into physical fights, according to the study co-authored by scientists at Duke, Harvard, and Columbia ...

New study indicates that exercise improves non-alcoholic fatty liver disease

New study indicates that exercise improves non-alcoholic fatty liver disease
2015-04-08
Amsterdam, The Netherlands, April 8, 2015 -- Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world. A new study published in the Journal of Hepatology shows that exercise, regardless of frequency or intensity, benefits obese and overweight adults with NAFLD. NAFLD is considered the hepatic manifestation of metabolic syndrome and is commonly associated with obesity and diabetes. There are no approved drug treatments for NAFLD, but lifestyle interventions such as diet, exercise, and the resulting weight loss have ...

8 reasons the US Surgeon General should announce that UV tanning causes skin cancer

2015-04-08
A July, 2014 Call to Action to Prevent Skin Cancer by acting Surgeon General Dr. Boris Lushniak points out that indoor tanning is "strongly associated with increased skin cancer risk," but stops short of reporting that tanning causes cancer. A University of Colorado Cancer Center opinion published today in the American Journal of Preventive Medicine points out that UV tanning meets the same criteria as smoking as a cause of cancer and argues that announcing the causality could save lives. "In 1964 when the Surgeon General finally reported that smoking causes lung cancer, ...

The hoo's hoo of gibbon communication

2015-04-08
The secret communication of gibbons has been interpreted for the first time in a study published in the open access journal BMC Evolutionary Biology. The research reveals the likely meaning of a number of distinct gibbon whispers, or 'hoo' calls, responding to particular events and types of predator, and could provide clues on the evolution of human speech. While lar gibbons (Hylobates lar) are mainly known for their loud and conspicuous songs, they can also produce a number of soft call types known as 'hoo's. These subtle calls have been alluded to in studies dating ...

Into thin air and back

2015-04-08
Life has adapted to all sorts of extreme environments on Earth, among them, animals like the deer mouse, shimmying and shivering about, and having to squeeze enough energy from the cold, thin air to fuel their bodies and survive. Now, in a new publication in the journal Molecular Biology and Evolution, Scott, Cheviron et al., have examined the underlying muscle physiology from a group of highland and lowland deer mice. Deer mice were chosen because they exhibit the most extreme altitude range of any North American mammal, occurring below sea levels in Death Valley to ...

Discovery of communication link between brain areas implicated in schizophrenia

Discovery of communication link between brain areas implicated in schizophrenia
2015-04-08
Cold Spring Harbor, NY - The prefrontal cortex (PFC) plays an important role in cognitive functions such as attention, memory and decision-making. Faulty wiring between PFC and other brain areas is thought to give rise to a variety of cognitive disorders. Disruptions to one particular brain circuit--between the PFC and another part of the brain called the thalamus--have been associated with schizophrenia, but the mechanistic details are unknown. Now, Cold Spring Harbor Laboratory scientists have discovered an inhibitory connection between these brain areas in mice that ...

Newly discovered ancient arthropod lived hundreds of millions of years ago

2015-04-07
The Burgess Shale Formation, in the Canadian Rockies of British Columbia, is one of the most famous fossil locations in the world. A recent Palaeontology study introduces a 508 million year old (middle Cambrian) arthropod--called Yawunik kootenayi--from exceptionally preserved specimens of the new Marble Canyon locality within the Burgess Shale Formation. Its frontal appendage--the "megacheiran great appendage"--is remarkably adorned with teeth, emphasizing an advanced predatory function. The appendage also had long hair-like flagella at the end that likely served a sensory ...

The rest of the brain gets in the way

The rest of the brain gets in the way
2015-04-07
Why do some people learn a new skill right away, while others only gradually improve? Whatever else may be different about their lives, something must be happening in their brains that captures this variation. Researchers at the University of Pennsylvania, the University of California, Santa Barbara, and Johns Hopkins University have taken a network science approach to this question. In a new study, they measured the connections between different brain regions as participants learned to play a simple game. The differences in neural activity between the quickest and slowest ...

A better biomarker to predict cetuximab response in CRC patients

A better biomarker to predict cetuximab response in CRC patients
2015-04-07
The results appear in the 2015 2nd issue of the journal of Human Genome Variation. To see a video about the partnership between Champions and Insilico, visit: http://tinyurl.com/InsilicoChampions . Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer deaths in the United States. More than 50,000 people die of CRC each year due to tumor spreading to other organs and almost half of all newly diagnosed patients are in an advanced stage of cancer (metastatic CRC or mCRC) when they are first diagnosed. With the development ...

Common drug is re-engineered to improve surgery outcomes

2015-04-07
A Northwestern University research team potentially has found a safer way to keep blood vessels healthy during and after surgery. During open-heart procedures, physicians administer large doses of a blood-thinning drug called heparin to prevent clot formation. When given too much heparin, patients can develop complications from excessive bleeding. A common antidote is the compound protamine sulfate, which binds to heparin to reverse its effects. "Protamine is a natural compound that has been used in surgeries for many decades," said Guillermo Ameer, professor of biomedical ...

Easing the pain

2015-04-07
The combination of two well-known drugs will have unprecedented effects on pain management, says new research from Queen's. Combining morphine, a narcotic pain reliever, and nortriptyline, an antidepressant, has been found to successfully relieve chronic neuropathic pain - or a localized sensation of pain due to abnormal function of the nervous system - in 87 per cent of patients, and significantly better than with either drug alone. "Chronic pain is an increasingly common problem and can exert disastrous personal, societal, and socio-economic impacts on patients, their ...

Stanford-led study finds limited mutations involved in transmission of drug-resistant HIV

2015-04-07
In the largest study of its kind to date, researchers at Stanford University School of Medicine and their colleagues have found that worldwide only a limited number of mutations are responsible for most cases of transmission of drug-resistant HIV. HIV, the virus that causes AIDS, can mutate in the presence of antiviral drugs, and these mutations can be transmitted from one person to the next. In the new study of more than 50,000 patients in 111 countries, the researchers found a small group of mutations accounted for a majority of the cases of transmission-related resistance ...

Leading cardiovascular societies release new guidance on use of heart pumps

2015-04-07
Washington, DC (April 7, 2015) - Greater availability of percutaneous mechanical circulatory support (MCS) devices for treatment of heart failure is helping expand treatment options for a rapidly growing number of acutely and chronically ill cardiac patients who could benefit from the devices. An expert consensus statement released today by the Society for Cardiovascular Angiography and Interventions (SCAI), American College of Cardiology (ACC), Heart Failure Society of America (HFSA) and The Society of Thoracic Surgeons (STS) provides new guidance to help physicians match ...
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