Led by a University of Oklahoma professor, an international team of researchers has discovered the first evidence of milk consumption in the ancient dental calculus--a mineralized dental plaque--of humans in Europe and western Asia. The team found direct evidence of milk consumption preserved in human dental plaque from the Bronze Age to the present day. "The study has far-reaching implications for understanding the relationship between human diet and evolution," said Christina Warinner, professor in the OU Department of Anthropology. "Dairy products are a very recent, ...

Researchers have discovered a mechanism linked to the brain damage often suffered by stroke victims--and are now searching for drugs to block it. Strokes happen when the blood supply to part of the brain is cut off but much of the harm to survivors' memory and other cognitive function is often actually caused by "oxidative stress" in the hours and days after the blood supply resumes. A team from the University of Leeds and Zhejiang University in China studied this second phase of damage in laboratory mice and found a mechanism in neurons that, if removed, reduced the ...

A large-scale study led by the University of Exeter has found that boys are more likely to be stillborn than girls. Published in the journal BMC Medicine, the study reviewed more than 30 million births globally, and found that the risk of stillbirth is about ten percent higher in boys. This equates to a loss of around 100 000 additional male babies per year. The results could help to explain why some pregnancies go wrong. Around a quarter of stillbirths have no known cause. Of the remainder, many are linked to placental abnormalities but it is often unclear why the abnormalities ...

Drinking 3-5 cups of coffee per day may help to protect against Alzheimer's Disease, according to research highlighted in an Alzheimer Europe session report published by the Institute for Scientific Information on Coffee (ISIC), a not-for-profit organisation devoted to the study and disclosure of science related to coffee and health. The number of people in Europe aged over 65 is predicted to rise from 15.4% of the population to 22.4% by 20251 and, with an aging population, neurodegenerative diseases such as Alzheimer's Disease are of increasing concern. Alzheimer's Disease ...

Using world-leading research methods, the team of Dr David Wright and Prof Paul Holmes, working with Dr Jacqueline Williams from the Victoria University in Melbourne, studied activity in an area of the brain responsible for controlling movements when healthy participants observed a video showing simple hand movements and simultaneously imagined that they were performing the observed movement. Using transcranial magnetic stimulation - a technique where a coil placed over the scalp delivers a stimulation to the brain, activates neurons in the underlying area, and causes ...

TORONTO, Nov. 26, 2014 - Ontario students between Grades 9 and 12 who said they had a traumatic brain injury in their lifetime, also reported drug use rates two to four times higher than peers with no history of TBI, according to research published today in The Journal of Head Trauma Rehabilitation. "Overall, a teen with a history of TBI is at least twice as likely as a classmate who hasn't suffered a brain injury to drink alcohol, use cannabis or abuse other drugs," said Dr. Michael Cusimano, co-principal investigator of the study and a neurosurgeon at St. Michael's ...

This news release is available in French. The world's first clinical trial comparing three alternative treatments for type 1 diabetes was conducted in Montréal by researchers at the IRCM and the University of Montreal, led by endocrinologist Dr. Rémi Rabasa-Lhoret. The study confirms that the external artificial pancreas improves glucose control and reduces the risk of hypoglycemia compared to conventional diabetes treatment. The results, published today in the scientific journal The Lancet Diabetes & Endocrinology, could have a significant impact on the ...

Leading medical experts today [Thursday 27 November] warn that rising numbers of deaths from liver disease - already the UK's third commonest cause of premature death - will be unavoidable without radical improvements in treatment and detection services, and tougher government policies to control the excessive alcohol use and obesity responsible for much of the national burden of liver disease. In a major new Lancet Commission, led by Professor Roger Williams, Director of the Institute of Hepatology, London, UK, doctors and medical scientists from across the UK call ...

Boston, MA. Wednesday, November 26, 2014 -- Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and Harvard-affiliated hospitals have uncovered an easily detectable, "pre-malignant" state in the blood that significantly increases the likelihood that an individual will go on to develop blood cancers such as leukemia, lymphoma, or myelodysplastic syndrome. The discovery, which was made independently by two research teams affiliated with the Broad and partner institutions, opens new avenues for research aimed at early detection and prevention of ...

TORONTO, Nov. 26, 2014--The nervous system may play a bigger role in infections and autoimmune diseases than previously known. If researchers can learn more about that role, it could provide insight into diagnosing and treating everything from the stomach flu to rheumatoid arthritis. Researchers at St. Michael's Hospital in Toronto, in conjunction with the Feinstein Institute for Medical Research in Manhasset, N.Y., reviewed the latest, most vigorous pre-clinical trials on this topic in a commentary published Wednesday (Nov. 26) in the New England Journal of Medicine. ...

An experimental vaccine to prevent Ebola virus disease was well-tolerated and produced immune system responses in all 20 healthy adults who received it in a Phase 1 clinical trial conducted by researchers from the National Institutes of Health. The candidate vaccine, which was co-developed by the NIH's National Institute of Allergy and Infectious Diseases (NIAID) and GlaxoSmithKline (GSK), was tested at the NIH Clinical Center in Bethesda, Maryland. The interim results are reported online in advance of print in the New England Journal of Medicine. "The unprecedented scale ...

ANN ARBOR--The spaghetti-like internal structure of most plastics makes it hard for them to cast away heat, but a University of Michigan research team has made a plastic blend that does so 10 times better than its conventional counterparts. Plastics are inexpensive, lightweight and flexible, but because they restrict the flow of heat, their use is limited in technologies like computers, smartphones, cars or airplanes--places that could benefit from their properties but where heat dissipation is important. The new U-M work could lead to light, versatile, metal-replacement ...

MINNEAPOLIS - The majority of people with dementia have never seen a doctor about their memory and thinking problems, according to a new study published in the November 26, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. In the study, 55 percent of the people with dementia had never had an evaluation of their thinking and memory skills with a doctor. "These results suggest that approximately 1.8 million Americans over the age of 70 with dementia have never had an evaluation of their cognitive abilities," said study author ...

ANN ARBOR, Mich. -- Despite clear signs that their memory and thinking abilities have gone downhill, more than half of seniors with these symptoms haven't seen a doctor about them, a new study finds. University of Michigan researchers and their colleagues say their findings suggest that as many as 1.8 million Americans over the age of 70 with dementia are not evaluated for cognitive symptoms by a medical provider, which in some patients can lead to a failure to uncover modifiable causes of thinking or memory impairment. The study, published online in Neurology, the ...

Juvenile offenders with multiple psychiatric disorders when they are incarcerated in detention centers appear to be at high risk for disorders five years after detention, according to a report published online by JAMA Psychiatry. Psychiatric disorders are prevalent among juvenile detainees. However, far less is known about the young people after they leave detention. Karen M. Abram, Ph.D., of the Northwestern University Feinberg School of Medicine, Chicago, and co-authors looked at patterns of comorbidity (the presence of two or more disorders), how they change over ...

FLAGSTAFF, Ariz. -- Nov. 26, 2014 -- An international team of scientists from the Translational Genomics Research Institute (TGen) and The Luxembourg Centre for Systems Biomedicine (LCSB) have completed a first-of-its-kind microbial analysis of a biological wastewater treatment plant that has broad implications for protecting the environment, energy recovery and human health. The study, published Nov. 26 in the scientific journal Nature Communications (DOI: 10.1038/ncomm6603), describes in unprecedented detail the complex relationships within a model ecosystem. The ...

Johns Hopkins researchers report that their test of an interventional X-ray guidance device approved by the U.S. Food and Drug Administration in 2013 has the potential to reduce the radiation exposure of patients undergoing intra-arterial therapy (IAT) for liver cancer. In a report prepared for presentation Dec. 3 at the 100th annual meeting of the Radiological Society of North America in Chicago (abstract #SSM24-02), the researchers described the results of a clinical trial of the imaging system AlluraClarity, made by Philips Healthcare, on 50 patients with liver cancer. ...

Plasmid DNA attached to the outer surface of a sounding rocket may be able to withstand rocket launch, a period of residence in suborbital space, re-entry, and landing conditions into the Earth's atmosphere, all the while staying intact and active in its function as carrier of genetic information, according to a study published November 26, 2014 in the open-access journal PLOS ONE by Cora Thiel and Oliver Ullrich from University of Zurich and colleagues. DNA plays an important role as a biomarker for the search of extraterrestrial signatures of life, and scientists are ...

Potential 'vampires' buried in northwestern Poland with sickles and rocks across their bodies were likely local and not immigrants to the region, according to a study published November 26, 2014 in the open-access journal PLOS ONE by Lesley Gregoricka from University of South Alabama and colleagues. In northwestern Poland, apotropaic funerary rites--a traditional practice intended to prevent evil--occurred throughout the 17th-18th c. AD. Those of the dead considered at risk for becoming vampires for a variety of reasons were given specific treatment, and investigating ...

Shifts in the timing and duration of ice cover, especially the possible lengthening of ice-free periods, may impact polar bears under projected warming before the end of the 21st century, according to a study published November 26, 2014 in the open-access journal PLOS ONE by Stephen Hamilton from University of Alberta and colleagues. Sea ice across the Arctic is declining and altering physical characteristics of marine ecosystems, and polar bears are vulnerable to these changes in sea ice conditions. The authors of this study used sea ice projections for the Canadian ...

Induced pluripotent stem cells made from patients with a form of blistering skin disease can be genetically corrected and used to grow back healthy skin cells in laboratory dishes, researchers at the Stanford University School of Medicine have found. They've termed the new technique "therapeutic reprogramming." The skin cells formed normal human skin when grafted onto the backs of laboratory mice, they said. The findings represent a major advance in the battle against the disease, epidermolysis bullosa, in which the top layer of skin, called the epidermis, sloughs off ...

Some people say that reading "Harry Potter and the Sorcerer's Stone" taught them the importance of friends, or that easy decisions are seldom right. Carnegie Mellon University scientists used a chapter of that book to learn a different lesson: identifying what different regions of the brain are doing when people read. Researchers from CMU's Machine Learning Department performed functional magnetic resonance imaging (fMRI) scans of eight people as they read a chapter of that Potter book. They then analyzed the scans, cubic millimeter by cubic millimeter, for every four-word ...

Applied to the outer shell of the payload section of a rocket using pipettes, small, double-stranded DNA molecules flew into space from Earth and back again. After the launch, space flight, re-entry into Earth's atmosphere and landing, the so-called plasmid DNA molecules were still found on all the application points on the rocket from the TEXUS-49 mission. And this was not the only surprise: For the most part, the DNA salvaged was even still able to transfer genetic information to bacterial and connective tissue cells. "This study provides experimental evidence that the ...

Scientists investigating the potentially deadly hantavirus have used a novel approach to developing protective antibodies against it. Their work, published in today's online edition of Science Translational Medicine, provides proof of concept for producing antibodies against a broad range of human pathogens. Hantaviruses cause a condition known as hantavirus pulmonary syndrome (HPS), which has a case fatality rate of 35-40 percent. Currently there are no licensed vaccines, prophylactics, or therapeutics to prevent or treat this highly pathogenic disease. This research ...

This news release is available in German. Scientists led by Kristina Djinović-Carugo at the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna have elucidated the molecular structure and regulation of the essential muscle protein α-actinin. The new findings allow unprecedented insights into the protein's mode of action and its role in muscle disorders. The findings, made in collaboration with King's College London (KCL), may lead to improved treatments, and are published in the top-class journal Cell. Most ...