In a Policy Forum, Yue Zhu and colleagues provide an overview of China’s emerging regulation for artificial intelligence (AI) technologies and its potential contributions to global AI governance. Open-source AI systems from China are rapidly expanding worldwide, even as the country’s regulatory framework remains in flux. In general, AI governance suffers from fragmented approaches, a lack of clarity, and difficulty reconciling innovation with risk management, making global coordination especially hard in the face of rising controversy. Although ...

The secret to the naked mole-rats’ extraordinarily long life may lie in subtle changes to just four amino acids, researchers report. According to a new study, evolutionary mutations in cGAS – an enzyme in the innate immune system that senses DNA to trigger immune responses – may enhance the animal’s ability to repair aging-related genetic damage, whereas in other species, such as mice and humans, cGAS can suppress DNA repair. Wrinkled and unassuming though they appear, the naked mole-rat (Heterocephalus glaber) is an exceptionally long-lived rodent, with a maximum life span of nearly 40 years – roughly 10 times longer than ...

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells. A research team from the German Cancer Research Center (DKFZ) and the Institute of Molecular Pathology (IMP) in Vienna has now discovered that the acidic pH value in tumor tissue—known as acidosis—is a decisive factor in how pancreatic cancer cells adapt their energy metabolism in order to survive under these adverse conditions. The results were published in the journal Science. Poor blood circulation and increased metabolic activity often create hostile conditions in tumors: ...

From willow bark remedies to aspirin tablets, salicylic acid has long been part of human health. It also lies at the heart of how plants fight disease. Now, researchers at the University of Cambridge have developed a pioneering biosensor that allows scientists to watch, for the first time, how plants deploy this critical immune hormone in their battle against pathogens. Published today in Science, Dr Alexander Jones’ group at the Sainsbury Laboratory Cambridge University (SLCU) presents SalicS1, a genetically encoded biosensor that can detect and track the dynamics of ...

Most REDD+ forest carbon offset projects significantly overstate their climate benefits, according to a new study published in Science. The findings come from an international team of researchers, primarily based at the Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), China, with contributions from Prof. Dr. Jonathan Chase of the German Centre for Integrative Biodiversity Research (iDiv) and the Martin Luther University Halle-Wittenberg (MLU).  The study analysed 52 REDD+ initiatives, ...

After nearly 25 years of research, the mystery has finally been solved: Europe’s largest bat doesn’t just eat small birds – it hunts and captures them more than a kilometre above the ground. And it eats them without landing. An international team of researchers has shed light on how Europe’s largest bat hunts and consumes small birds. The results, now published in Science, make for fascinating reading – a story of nocturnal aerial acrobatics, pursuit and predation. Every year, billions of songbirds migrate between their breeding grounds and wintering areas. Many species fly high and travel at night, partly to avoid daytime ...

A new study has mapped the distinct molecular “fingerprints” that 59 diseases leave in an individual’s blood protein – which would enable blood tests to discern troubling signs from those that are more common. Publishing today in Science, an international team of researchers mapped how thousands of proteins in human blood shift as a result of aging and serious diseases, such as cancer and cardiovascular and autoimmune diseases. The Human Disease Blood Atlas also reveals that each individual’s blood profile has a unique molecular ...

Francis Crick Institute press release  Under strict embargo: 19:00hrs BST Thursday 9th October 2025  Peer reviewed   Experimental study  Animals   Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key pathway for tumour growth.     Now entering the first clinical trial in humans, if found to be safe and effective, these drugs could be used to treat many different types of cancers while avoiding effects ...

New Orleans, LA - Ochsner Health announces the launch of its Genetic Wellness Assessment, an innovative screening tool to help identify individuals at risk for hereditary cancers. The Genetic Wellness Assessment is now available for adults interested in learning more about their cancer risk at Ochsner.org/GeneticWellnessSurvey.  The Genetic Wellness Assessment allows individuals to determine whether they may have a higher genetic risk of developing cancer by answering a few simple questions that ...

University of Arizona researchers may have uncovered a connection between chronic pain and a somewhat uncommon immune condition, opening the door to future research on immune biomarkers for chronic pain. A small study of medical records led by Julie Pilitsis, MD, PhD, professor and chair of the Department of Neurosurgery at the U of A College of Medicine – Tucson, unexpectedly found that 12% of chronic pain patients who were treated with spinal cord stimulation or an implanted pain medicine pump had a white blood cell condition called eosinophilia. The condition is often a result of something gone awry with the immune ...

Research conducted by Pompeu Fabra University (UPF) finds that discrimination exists based on ethnic background in Spain’s leading online second-hand marketplace, especially when it comes to buying, towards people with Arab and Chinese names, who should offer up to 3% more to be treated the same as people with Spanish names. The study, by Jorge Rodríguez Menés, Clara Cortina and Maria José González, researchers with the Sociodemography Research Group (DemoSoc) of the UPF Department of Political and Social Sciences, aims to analyse the prevalence of discrimination against ethnic minorities in the main online second-hand ...

True crime is a lucrative genre, topping ratings and spawning online communities. But despite its popularity — and its ability to highlight cases that need attention — the production of true crime has a dark side, often adding to the trauma experienced by victims’ loved ones. University of Nebraska–Lincoln scholar Kelli Boling published new research highlighting the impacts of true crime media on the family and friends of crime victims. Through in-depth interviews with 20 co-victims — all of whom experienced their ...

New research led by Bayes Business School (formerly Cass) has revealed the introduction of the National Living Wage (NLW) in the UK in April 2016 significantly decreased labour mobility across firms by minimum wage workers. While it has delivered a pay boost for many low-paid workers, the rising wage floor could be affecting the fluidity of the job market if it is reducing workers’ incentives to search for new jobs and move between firms. The National Living Wage was introduced by the UK Government to replace the National Minimum Wage for workers aged 25 and over, initially raising the threshold hourly rate by 50 pence to £7.20. The rise represented ...

A research team in Japan has developed an innovative system that can accurately detect genetic mutations in the brain tumor within just 25 minutes. Genetic mutations are crucial markers for diagnosis of brain tumors. Unlike conventional genetic analysis methods, which typically take one to two days to obtain results, this new system allows surgeons to identify genotyping of brain tumors and determine optimal resection margins during surgery. The new system succeeded in detecting mutations in isocitrate dehydrogenase (IDH) and telomerase ...

**Under embargo until 11AM ET Thursday 10/9/25**   October 9, 2025   UMass Amherst Researchers Create Nanoparticle Vaccine That Prevents Cancer in Mice   The vaccine also proves highly effective at preventing cancer’s deadly spread   AMHERST, Mass. — A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice. Not only did up to 88% of the vaccinated mice remain tumor-free (depending on the cancer), but the vaccine reduced—and in some cases completely ...

Some dogs show behaviours towards their toys that resemble behavioural addictions in humans, such as gambling and internet gaming, according to a study of 105 dogs published in Scientific Reports.  Behavioural addictions in humans are characterised by compulsive engagement with activities despite negative consequences. Although anecdotal evidence has previously suggested that some dogs display addictive-like behaviours towards toys — for example whining when a toy is out of reach and continuing to play despite overexertion or injury — this study represents the first published scientific evaluation of such behaviours ...

The International Society for Stem Cell Research (ISSCR) is proud to announce the release of Best Practices for the Development of Pluripotent Stem Cell-Derived Cellular Therapies, a comprehensive, interactive new resource designed to accelerate the translation of human pluripotent stem cell (PSC)-derived therapies into clinical trials and commercial use. Developed by leading international experts in cell therapy, this groundbreaking document outlines the key principles and decision points required to develop safe, effective, and regulatory compliant PSC-derived products. Organized into seven sections, the guidance offers jurisdictionally neutral ...

Using millions of microscope images magnified up to 130,000 times, researchers from Radboud university medical center and Toronto have unraveled the structure of two key proteins in the malaria parasite. With this knowledge, scientists are developing new vaccines that block the transmission of parasites via mosquitoes. Malaria, a parasitic infectious disease, has existed since the time of the ancient Egyptians and still threatens nearly half of the world’s population. In recent years, two malaria vaccines have become available that protect against infection, but they ...

About The Study: The results of this study of World Trade Center (WTC) responders suggests that, when compared with the lowest reported exposure levels, a higher level of reported exposure to more particulate dust or debris was significantly associated with an increased incidence of lung cancer. Future studies may investigate specific WTC exposures and histologic changes and clarify the role of WTC exposure for prognosis.  Corresponding Author: To contact the corresponding author, Sean ...

This roundup highlights new insights into why acute myeloid leukemia resists treatment, racial disparities in triple-negative breast cancer, a potential strategy to make CAR T therapies stronger, early human trial results for an investigational new treatment for glioblastoma and a new approach to fighting pancreatic cancer — with a virus.  To learn more about research at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation’s top cancer centers ...

Beyond spirited dinner party debate, establishing which creatures have consciousness matters in terms of animal welfare and conservation policy. A Michigan State University philosophy scholar has added clarity to a messy philosophical debate. In this month’s journal Biology & Philosophy, PhD candidate Jonah Branding contributes a decision tree that can be applied to questions such as, do fish feel pain when they’re on a hook? Does an ant feel alarm when protecting its colony? Do banana slugs feel anything when they eat dead leaves on the forest floor? Or are these simpler organisms more like stimulus-response machines, which don’t have any mental experience? “There ...

Background and objectives MD-1 is a time-tested polyherbal diabetes supplement in Tamil Nadu, India. It is composed of dried powdered herbs: Phyllanthus amarus Schum. & Thonn, Tinospora cordifolia (Willd.) Miers ex Hook. F. & Thoms, Emblica officinalis Gaertn., Eugenia jambolana Lam., Gymnema sylvestre R. Br. Ex, and Cassia auriculata Linn. This study aimed to investigate the in vivo effects of MD-1 in high-fat diet (HFD)-induced diabetes mellitus in C57BL/6J mice. Methods After 10 weeks of HFD induction, diabetic mice (n = 60) ...

About The Study: Although the incidence of new-onset atrial fibrillation (AF) after coronary artery bypass grafting (CABG) in this study was higher than previously reported, the AF burden in these patients was very low, especially after 30 days. The very low AF burden questions the current guideline recommendations that long-term oral anticoagulation should be considered in patients with new-onset AF after CABG. Corresponding Author: To contact the corresponding author, Florian Herrmann, MD, email florian.herrmann@med.uni-muenchen.de. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2025.14891) Editor’s ...

About The Study: In this nationwide analysis, emergency Medicaid accounted for only a small fraction of total Medicaid expenditures. Although states with larger undocumented populations spent approximately 15 times more per capita, emergency Medicaid still constituted less than 1% of overall Medicaid spending even in states with large undocumented populations, posing a limited fiscal burden on Medicaid. These results suggest that cuts to emergency Medicaid will produce minimal overall cost savings and will disproportionately harm states with large undocumented populations. Corresponding Author: To ...

What it's about: Raw milk (untreated milk) enjoys a certain popularity, but poses health risks. To avoid food poisoning, it should be boiled before drinking. But how well is raw milk actually known among the population? How do people perceive its health risk? Two-thirds of those surveyed had already heard of raw milk. Only ten percent expressed concern, making raw milk the topic of least concern of the risks surveyed. This is according to the BfR Consumer Monitor, a regularly conducted representative survey by the German Federal Institute for Risk Assessment (BfR). “The health risks of raw milk ...