TTUHSC researchers find blood-brain barrier remains resilient in Alzheimer’s disease model
A team of scientists at Texas Tech University Health Sciences Center (TTUHSC) has published new evidence suggesting that the brain’s protective shield — known as the blood-brain barrier (BBB) — remains largely intact in a commonly used mouse model of Alzheimer’s disease. The discovery challenges long-standing assumptions that Alzheimer’s disease causes the BBB to “leak,” potentially reshaping how researchers think about drug delivery for the disease.
The study, published July 23 in Fluids and Barriers of the CNS, was conducted by a research team ...