Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye’s lens that occurs commonly in people as they age. The study, which was conducted in the 13-lined ground squirrel and rats, may represent a possible surgery-free strategy for managing cataracts, a common cause of vision loss.  The study published in the Journal of Clinical Investigation. “Scientists have long searched for an alternative to cataract surgery, which is effective, but not without risk. Lack of access to cataract surgery is a barrier to care in some ...

Tomorrow’s workplace will be run on mind-boggling amounts of data. To make sense of it all, businesses, developers and individuals will need better artificial intelligence (AI) systems, better trained AI workers and more efficient number-crunching servers. While big tech companies have the resources and expertise to meet these demands, they remain beyond the reach of most small and medium-sized enterprises and individuals. To respond to this need, a Concordia-led international team of researchers has developed a new framework to make complex AI tasks more accessible ...

BUFFALO, N.Y. — A University at Buffalo psychiatrist who has played a critical role in getting mental health screening and treatment integrated into routine care for adults and adolescents with cystic fibrosis (CF) has been awarded $3 million from the Cystic Fibrosis Foundation to focus on the mental health of children with the disease.   Led by UB and launched this summer, the new study is an outgrowth of The International Depression Epidemiological Study (TIDES), which began in 2014 and was the largest study of mental health in adolescents and adults with CF. As a result of TIDES, ...

The Universidad Carlos III de Madrid (UC3M) is one of 22 institutions that have been selected by the Ministry for Digital Transformation and the Civil Service to create an ENIA Chair to further the development of artificial intelligence (AI)-based applications. The AImpulsa UC3M-Universia Chair, as it is called, will be the only one of its kind in Spain in the area of Data Economy and will collaborate with Universia-Banco Santander, through Santander Universities. The ENIA Chairs' objectives, which depend on the Secretary of State for Digitalisation and Artificial Intelligence of the Ministry for Digital Transformation and ...

Anyone who has ever pet a cat or shuffled their feet across the carpet knows that rubbing objects together generates static electricity. But an explanation for this phenomenon has eluded researchers for more than two millennia. Now, Northwestern University scientists have finally uncovered the mechanics at play.  When an object slides, the front and back parts of that object experience different forces, researchers found. This difference in forces causes different electrical charges to build up on the front and back parts of the object. And the difference in electrical charges creates a current, leading to a light zap. The study was published yesterday (Sept. 17) in the journal ...

UC San Diego Health has been honored as a top performer for Vizient’s 2024 Bernard A. Birnbaum, MD, Quality Leadership Performance Award, marking the sixth consecutive year the health system has achieved this prominent distinction. This award places UC San Diego Health among the top academic medical centers in the nation, highlighting its exceptional commitment to delivering high-quality, patient-centered care. This sustained excellence recognizes the region’s only academic medical center’s mission of advancing health care standards and outcomes at the highest level. “Being named a Vizient top performer for the sixth year in a row underscores ...

As human population and development continue to expand, it’s more important than ever to set aside corridors of undeveloped land where wildlife can travel safely, helping to ensure their long-term survival. However, a recent study by the University of Maryland reveals that current methods of designing and evaluating wildlife corridors may not be adequate to ensure wildlife protection, and suggests that Best Management Practices should include analyzing corridors with a smarter and more thorough framework. University researchers tested different ...

The sea surface temperature in the Fijian archipelago in the southwestern Pacific is now at its maximum for more than 600 years. This is the result of an international research team's evaluation of a new coral record providing further evidence for unprecedented warming in the western Pacific Ocean. According to this, the year 2022 was the warmest year in the region since 1370. The scientists used the giant coral Diploastrea heliopora colony in Fiji to obtain the data for the new reconstruction. These unique and long-lived massive corals record long-term climatic and ...

AMHERST, Mass. – A new study by University of Massachusetts Amherst researchers demonstrates the effectiveness of homemade play putty at reading brain, heart, muscle and eye activity. Published in Device, the research outlines the conductive properties of this material, so-named “squishy circuits.”  “[Squishy circuits] are literally child’s play putty, that is also conductive” describes Dmitry Kireev, assistant professor of biomedical engineering and senior author on the paper.   The conductive squishy ...

In a rare and extraordinary discovery, researchers have identified a unique configuration of galaxies that form the most exquisitely aligned gravitational lens found to date. The Carousel Lens is a massive cluster-scale gravitational lens system that will enable researchers to delve deeper into the mysteries of the cosmos, including dark matter and dark energy. “This is an amazingly lucky ‘galactic line-up’ – a chance alignment of multiple galaxies across a line-of-sight spanning most of the observable universe,” said David Schlegel, a co-author of the study and a senior scientist in Berkeley Lab’s Physics Division. "Finding one such alignment is ...

A newly identified wasp species, Chrysonotomyia susbelli, has been discovered in Houston, Texas, marking the 18th new species identified by Rice University’s Scott Egan and his research team since 2014. The discovery, the fourth wasp species found on the university grounds in seven years, reveals the hidden world of parasitoid wasps and the intricate ecosystems that thrive outside our doors. The Chrysonotomyia susbelli is a parasitoid wasp, about 1 millimeter long, that emerges from galls, or tumorlike growths created by the gall wasp Neuroterus bussae found on southern live oak leaves. The galls serve as microhabitats within which larvae feed, develop and pupate. ...

Researchers have achieved a groundbreaking advancement in plant biotechnology by using a magnetofected pollen gene delivery system to genetically transform cucumbers. This cutting-edge method uses DNA-coated magnetic nanoparticles to introduce foreign genes into pollen, producing genetically modified seeds without the need for traditional tissue culture or regeneration steps. This technique significantly streamlines and accelerates crop genetic modification, opening up new avenues to boost agricultural productivity and resilience. Genetic modification in horticultural crops, particularly within the Cucurbitaceae family, is often hindered by complex tissue culture requirements and ...

Some of the greatest discoveries don’t come merely from observations but from thinking. Einstein developed theories about relativity through thought experiments, and Galileo derived insights about gravity through mental simulations. A review published September 18 in the journal Trends in Cognitive Sciences shows that this process of thinking is not exclusive to humans. Artificial intelligence, too, is capable of self-correction and arriving at new conclusions through “learning by thinking.” “There are some recent demonstrations of what looks like learning by thinking in AI, ...

In an opinion article publishing September 18 in the Cell Press journal Trends in Molecular Medicine, physician-scientists argue that with most placentas discarded after birth, placental pathology is underutilized clinically, should be a routine part of obstetric and neonatal care, and also deserves more research attention. “Placentas should not be considered a waste tissue,” says senior author Mana Parast, MD, PhD, professor of pathology at University of California San Diego School of Medicine. ...

Drug overdose mortality has risen faster among adolescents than the general population in recent years, largely due to fentanyl, a potent opioid pain medication. A new study published in JAMA sheds light on trends in nonfatal opioid overdoses in youth – an area that was not as well characterized, but key to formulating prevention strategies to save lives. Researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago and colleagues analyzed data using Emergency Medical Services (EMS) encounters from January 2018 to December 2022. They found that opioid overdoses in youth increased at pandemic onset and remained elevated compared to pre-pandemic levels. The majority ...

About The Study: Prehospital encounters for youth opioid overdoses were increasing prior to the pandemic, increased with the onset, and then stabilized, remaining higher than pre-pandemic levels. Although overall patterns were largely driven by those ages 18 through 24, adolescents ages 12 through 17 were the only subgroup with an increasing number of encounters both before and during the pandemic. Corresponding Author: To contact the corresponding author, Jamie Lim, MD, email jlim@luriechildrens.org. To access the embargoed study: Visit our ...

** Caltech is hosting an embargoed media zoom about this result on Monday, September 16 at 10am Pacific/1pm Eastern. You can register here:  https://caltech.zoom.us/webinar/register/WN_gYEV5Tl1S0uZkZG1gDIEnQ#/registration Astronomers have spotted the biggest pair of black hole jets ever seen, spanning 23 million light-years in total length. That's equivalent to lining up 140 Milky Way galaxies back to back.  "This pair is not just the size of a solar system, or a Milky Way; we are talking about 140 Milky Way diameters in total," says Martijn ...

About The Study: In this study, the overall survival of the face transplants is encouraging. These data suggest that the acceptable long-term survival of face transplants makes them a reconstructive option for extensive facial defects. Quote from corresponding author Pauliina Homsy, MD, PhD: “A total of 50 face transplants have been performed since 2005. Activity has been concentrated with only 18 centers in 11 countries giving this treatment. Our study demonstrates an overall 5- and 10-year survival of face transplants ...

About The Study: In this cohort study of 1.5 million patients seeking preventive care, denials of insurance claims for preventive care were disproportionately more common among at-risk patient populations. This administrative burden potentially perpetuates inequitable access to high-value health care.  Corresponding Author: To contact the corresponding author, Alex Hoagland, PhD, email alexander.hoagland@utoronto.ca. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.33316) Editor’s ...

About The Study: The results of this randomized clinical trial showed that transitioning insomnia care for older adults away from long-term sedative use and toward cognitive behavioral therapy for insomnia can be achieved using a mailed, direct-to-patient approach.  Corresponding Author: To contact the corresponding author, David M. Gardner, PharmD, MSc CH&E, email david.gardner@dal.ca. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (10.1001/jamapsychiatry.2024.2731) Editor’s ...

Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing accuracy and interpretability. Investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, used advanced machine learning to increase the accuracy of a national cardiovascular risk calculator while preserving its interpretability and original risk associations. Their results showed higher accuracy overall in an electronic health records cohort ...

One of the main targets of Russia’s ongoing attacks on Ukraine is the energy infrastructure. The extent of the destruction is enormous. “One year after the start of the war in February 2022, 76 percent of thermal power plants had been destroyed; now the figure is 95 percent,” says Ukrainian scientist Iryna Doronina. “And all the large hydroelectric power plants have also failed.” The breaching of the Kakhovka dam proved to be particularly devastating. The huge outflow of water – the reservoir ...

Media Contact: laura.kurtzman@ucsf.edu, (415) 502-6397 Subscribe to UCSF News After a spinal cord injury, nearby cells quickly rush to action, forming protective scar tissue around the damaged area to stabilize and protect it. But over time, too much scarring can prevent nerves from regenerating, impeding the healing process and leading to permanent nerve damage, loss of sensation or paralysis.  Now, UC San Francisco researchers have discovered how a rarely studied cell type controls the formation of scar tissue in spinal cord injuries. Activating ...

Scientists have pinpointed thousands of genetic changes in a gene that may increase a person’s risk of developing breast and ovarian cancer, paving the way for better risk assessment and more personalised care.  Researchers from the Wellcome Sanger Institute and their collaborators focused on the ‘cancer protection’ gene RAD51C, finding over 3,000 harmful genetic changes that could potentially disrupt its function and increase ovarian cancer risk six-fold and risk of aggressive subtypes of breast ...

Metal exposure from environmental pollution is associated with increased calcium buildup in the coronary arteries at a level comparable to traditional risk factors like smoking and diabetes, according to a study published today in JACC, the flagship journal of the American College of Cardiology. The findings support that metals in the body are associated with the progression of plaque buildup in the arteries and potentially provide a new strategy for managing and preventing atherosclerosis. "Our findings highlight the importance ...