Research untangles role of stress granules in neurodegenerative disease
2025-05-28
(MEMPHIS, Tenn. and ST. LOUIS, MO.– May 28, 2025) Scientists from St. Jude Children’s Research Hospital and Washington University in St. Louis report mechanistic insights into the role of biomolecular condensation in the development of neurodegenerative disease. The collaborative research, published in Molecular Cell, focused on the interactions that drive the formation of condensates versus the formation of amyloid fibrils and how these relate to stress granules. Stress granules are biomolecular condensates that form under conditions of cellular stress and have been previously implicated as drivers of amyotrophic lateral sclerosis ...
Whether it's smoking or edibles, marijuana is bad for your heart
2025-05-28
A new study led by UC San Francisco researchers finds that chronic cannabis use — whether it’s smoked or consumed in edible form — is associated with significant cardiovascular risks. 
The report, published May 28 in JAMA Cardiology, found that people who regularly used marijuana in either form had reduced blood vessel function that was comparable to tobacco smokers. Vascular function in those who used cannabis by either means was reduced roughly by half compared to those who did not use it. 
Decreased vascular function is associated with ...
New injection could help millions with high blood pressure
2025-05-28
Results from a clinical trial led by researchers from Queen Mary University of London, published today in JAMA, show that giving people with high blood pressure an injection every six months can lead to a meaningful, sustained reduction in their blood pressure. 
The global trial, KARDIA-2, involved 663 people with high blood pressure whose condition wasn’t being well managed with their standard treatment.  
In the trial, patients were given an injection of a new medication zilebesiran, alongside their standard blood pressure treatments. Researchers found ...
Study finds home healthcare agencies discontinuing telehealth post-pandemic
2025-05-28
Irvine, Calif., May 28, 2025 — Many home healthcare agencies adopted telehealth services during the COVID-19 pandemic, but the absence of federal reimbursements for these services has led to an increasing number of providers discontinuing these options, a national survey conducted by the University of California, Irvine, and other institutions reveals. Results are published in Health Services Research.
 
The National Institute on Aging-funded study offers valuable insights into the role of telehealth ...
Involving communities in nature-based solutions to climate challenges leads to greater innovation, study shows
2025-05-28
Involving communities in nature-based solutions to tackle urban climate and environmental challenges leads to innovation and multiple benefits, a study shows.
Participation of citizens in NBS projects leads to innovation in design and quality, as well as people gaining greater benefits from green and blue spaces (for access, recreation and health and wellbeing), researchers found. The study showed that involving communities.
Projects are also more likely to be successful in supporting nature renewal ...
Meet your next AGA president: Dr. Lawrence Kim
2025-05-28
Bethesda, MD (May 28, 2025) — Lawrence Kim, MD, AGAF, today begins his term as the 120th president of the AGA Institute. A leader in community-based practice, Dr. Kim is a partner at South Denver Gastroenterology, an independent gastroenterology practice in Colorado. 
In his 27 years in private practice, Dr. Kim has helped diversify and innovate his group. He developed a part-time partnership model, making South Denver Gastroenterology a leader in recruiting women gastroenterologists, who now comprise one-third of the practice. He incorporated ...
Even birds can’t outfly climate change
2025-05-28
New Haven, Conn. — As rising global temperatures alter ecosystems worldwide, animal species usually have two choices: adapt to changing local conditions or flee to a cooler clime. Ecologists have long assumed that the world’s bird species were best equipped to respond to the pressures of climate change simply because they have the option of flying to higher altitudes or towards global poles.
But a new Yale study finds that few bird species are able to escape the realities of a warming world.
The findings were published May 28 in the journal Nature Ecology and Evolution.
“They can’t move fast enough or far enough to ...
Electric buses struggle in the cold, Cornell researchers find
2025-05-28
CORNELL UNIVERSITY MEDIA RELATIONS OFFICE
FOR RELEASE: May 28, 2025
 
Kaitlyn Serrao
607-882-1140
kms465@cornell.edu
 
Electric buses struggle in the cold, Cornell researchers find
 
ITHACA, N.Y. – Cornell University researchers have released new insights on a pilot program involving all-electric buses in Ithaca – with implications for cities, schools and other groups that are considering the electrification of their fleets, as well as operators, policymakers and manufacturers.
 
The study is the first to assess and analyze electric buses’ performance in the northeastern U.S., with an unprecedented dataset that covers significant ...
A switchboard with precision: How the brain licenses movements
2025-05-28
Neurons deep in the brain not only help to initiate movement—they also actively suppress it, and with astonishing precision. This is the conclusion of a new study by researchers at the University of Basel and the Friedrich Miescher Institute for Biomedical Research (FMI), published in the journal Nature. The findings are especially relevant for better understanding neurological disorders such as Parkinson’s disease.
Reaching for an apple or bringing a spoon to the mouth—these seemingly simple actions rely on highly complex processes in the brain. A key ...
Association of endothelial dysfunction with chronic marijuana smoking and THC-edible use
2025-05-28
About The Study: This cross-sectional study found that chronic cannabis smoking and tetrahydrocannabinol (THC) ingestion were associated with endothelial dysfunction similar to that observed in tobacco smokers, although apparently occurring via distinct mechanisms.
Corresponding author: To contact the corresponding author, Matthew L. Springer, Ph.D., email matt.springer@ucsf.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi: 10.1001/jamacardio.2025.1399)
Editor’s Note: Please see the article for additional information, including other authors, author contributions ...
Early-life low lead levels and academic achievement in childhood and adolescence
2025-05-28
About The Study: In this cohort study assessing early life low lead level and children’s and adolescents’ academic achievement, a 1-unit increase in lead levels in the range currently considered low for further interventions was associated with worse academic performance throughout school grades comparable to that for lead levels in the range recommended for additional interventions. These findings support the need to reconsider and potentially lower current blood lead reference values for recommending further interventions.
Corresponding author: To contact the corresponding author, George ...
Mother’s warmth in childhood influences teen health by shaping perceptions of social safety
2025-05-28
Parental warmth and affection in early childhood can have life-long physical and mental health benefits for children, and new UCLA Health research points to an important underlying process: children’s sense of social safety.
The study, published in JAMA Psychiatry, found that children who experience more maternal warmth at age 3 have more positive perceptions of social safety at age 14, which in turn predicts better physical and mental health outcomes at age 17.
Greater maternal warmth, defined as more praise, positive tone of voice and acts of affection, ...
Nature study reveals novel strategy for in vivo blood stem cell gene therapy
2025-05-28
A team of scientists from the San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget) in Milan, Italy, has identified a unique window shortly after birth in which circulating blood stem cells can be effectively targeted with gene therapy directly in the body. The study, published in Nature, opens new avenues for treating some genetic blood disorders without the need for stem cell transplantation or chemotherapy. 
SR-Tiget is internationally recognized as a leading center for lentiviral vector–based ...
Observing one-dimensional anyons: Exotic quasiparticles in the coldest corners of the universe
2025-05-28
Nature categorizes particles into two fundamental types: fermions and bosons. While matter-building particles such as quarks and electrons belong to the fermion family, bosons typically serve as force carriers—examples include photons, which mediate electromagnetic interactions, and gluons, which govern nuclear forces. When two fermions are exchanged, the quantum wave function picks up a minus sign, i.e., mathematically speaking, a phase of pi. This is totally different for bosons: Their phase upon exchange is zero. This quantum statistical property has drastic consequences for the behaviour of ...
Cosmic mystery deepens as astronomers find object flashing in both radio waves and X-rays
2025-05-28
Astronomers from the International Centre for Radio Astronomy Research (ICRAR), in collaboration with international teams, have made a startling discovery about a new type of cosmic phenomenon. 
The object, known as ASKAP J1832-0911, emits pulses of radio waves and X-rays for two minutes every 44 minutes.
This is the first time objects like these, called long-period transients (LPTs), have been detected in X-rays. Astronomers hope it may provide insights into the sources of similar mysterious signals ...
Solitonic superfluorescence paves way for high-temperature quantum materials
2025-05-28
A new study in Nature describes both the mechanism and the material conditions necessary for superfluorescence at room temperature. The work could serve as a blueprint for designing materials that allow exotic quantum states – such as superconductivity, superfluidity or superfluorescence – at high temperatures, paving the way for applications such as quantum computers that don’t require extremely low temperatures to operate.
The international team that did the work was led by North ...
Advanced protection strategy of lithium metal anodes
2025-05-28
Lithium metal batteries (LMBs), with its unparalleled theoretical energy density (up to 950 Wh kg⁻¹), have long been hailed as the future of energy storage. However, persistent challenges—such as dendrite formation, unstable interfaces, and safety concerns—have hindered their commercialization. Researchers from Zhengzhou University present a roadmap to overcome these obstacles, offering transformative solutions for the next generation of LMBs.
 
The team published their work in Materials and Solidification on April 15, 2025.
 
Key Innovations and ...
Unlocking the SDGs: Circular economy solutions to boost sustainable consumption
2025-05-28
A paper describing the circular economy as a vital enabler for the sustainable use of resources to achieve the UN agenda for SDGs was published in the journal Circular Economy on 14 April 2025 (https://doi.org/10.1016/j.cec.2025.100140). In this article, Khajuria and co-authors focused on reuse, recycling, and resource optimization, which assist businesses, governments, and communities in achieving the Sustainable Development Goals (SDGs).
 
They published their study on 14 April 2025, in Circular ...
Drones and genetics team up for drought smarter wheat
2025-05-28
A new study shows how using drones with advanced cameras, ones that detect both heat and light, can help scientists better measure how field-grown wheat plants cope with climate change. By flying these drones over hundreds of wheat varieties, researchers could estimate key traits like how efficiently the plants breathe through their leaves, how leafy they are, and how much chlorophyll they have. They then matched these traits to specific genes in the wheat, identifying genetic markers linked to better performance under normal and dry conditions. ...
Gut bacteria may hold key to unlocking better cancer treatment
2025-05-28
Scientists have discovered a range of ‘biomarkers’ that could help to improve detection and treatment of gastrointestinal diseases (GIDs) such as gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD).
Researchers found that certain gut bacteria and metabolites are linked to each disease - suggesting that these biomarkers could help in early, less invasive diagnosis of GIDs, with some markers indicating risk across multiple diseases.
They used advanced machine learning and AI-based ...
Downconversion mechanoluminescence from lanthanide codoped heterojunctions
2025-05-28
Mechanoluminescence (ML) is a type of luminescence that occurs when a material emits light in response to an external mechanical stimulus, such as scratching, pressing, or stretching. Unlike electroluminescence (EL) or photoluminescence (PL), ML does not require an electric energy or light excitation; instead, it directly converts mechanical energy into optical emission. Then, devices fabricated from ML materials are inherently passive. This characteristic represents an intelligent and energy-efficient light-emission mode. However, most current ML research mainly focuses on the study of single-matrix materials, whose stress-induced ...
MicroRNAs in the regulation of immune response in cardiovascular diseases: New diagnostic and therapeutic tools
2025-05-28
Cardiovascular diseases (CVDs) continue to dominate global mortality statistics, with immune dysregulation emerging as a central feature in their pathogenesis. This review by Gareev et al. focuses on immune-derived microRNAs (immuno-miRs) as pivotal modulators of immune responses in cardiovascular settings, highlighting their roles in pathophysiology, diagnostic potential, and therapeutic promise.
 
Introduction
The authors introduce CVDs as a global health crisis, exacerbated by the interplay between immune dysregulation and cardiovascular remodeling. Immune cells like macrophages and T cells, ...
Amplifcation-free electrochemiluminescent biosensor for ultrasensitive detection of fusobacterium nucleatum using tetrahedral DNA-based CRISPR/Cas12a
2025-05-28
Fusobacterium nucleatum, a bacterium linked to colorectal cancer, possesses a specific gene called fadA that serves as an early diagnostic biomarker. The CRISPR/Cas12a system has demonstrated marked potential for nucleic acid detection due to its satisfactory selectivity and trans-cleavage ability. However, most CRISPR/Cas-based sensors suffer from problems such as probe entanglement or local aggregation, reducing the Cas enzyme efficiency. “Electrochemiluminescence (ECL) has emerged as a sensitive method for detecting small molecules, nucleic acids, and proteins, due to its superior ...
Cutting-edge imaging breakthroughs for early breast cancer detection
2025-05-28
Breast cancer remains a leading cause of cancer-related mortality globally, underscoring the critical need for early detection to improve survival rates and reduce treatment invasiveness. This review synthesizes advancements in imaging technologies that enhance early diagnosis, focusing on their clinical applications, limitations, and future potential.
Introduction
Breast cancer accounts for 25% of cancer cases in women, with survival rates significantly higher in developed nations due to advanced screening programs. Traditional methods like clinical exams and mammography have been cornerstone tools, yet emerging technologies now complement these approaches, particularly ...
Yeast-driven and bioimpedance-sensitive biohybrid soft robots
2025-05-28
Recent advancements in flexible bioelectronics have demonstrated remarkable progress in achieving seamless integration at bio-tissue-electronic interfaces. However, persistent challenges such as foreign body response (FBR) due to mechanical mismatch and signal instability under dynamic physiological conditions remain critical barriers. "By synergizing bioinspired chemical modifications with microstructural topology, we developed a self-healing bioadhesive interface that eliminates reliance on external stimuli, overcoming the physiological ...
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