A chance meeting between two leading UK and US scientists could have finally helped solve a key mystery in cancer research. Scientists have long known that chromosomal defects occur as cells repeatedly divide. Over time, these defects are linked to the onset of cancer. Now, Professor Duncan Baird and his team from Cardiff University working in collaboration with Eric A. Hendrickson from the University of Minnesota, have identified a specific gene that human cells require in order to survive these types of defects. "We have found a gene that appears to be crucial ...

URBANA, Ill. – If the hottest new plant grown as a biofuel crop is approved based solely on its greenhouse gas emission profile, its potential as the next invasive species may not be discovered until it's too late. In response to this need to prevent such invasions, researchers at the University of Illinois have developed both a set of regulatory definitions and provisions and a list of 49 low-risk biofuel plants from which growers can choose. Lauren Quinn, an invasive plant ecologist at U of I's Energy Biosciences Institute, recognized that most of the news about invasive ...

NEW YORK (August 7, 2014) – The message is simple: to save elephants, all ivory markets must close and all ivory stockpiles must be destroyed, according to a new peer-reviewed paper by the Wildlife Conservation Society. The paper says that corruption, organized crime, and a lack of enforcement make any legal trade of ivory a major factor contributing to the demise of Africa's elephants. Appearing in the August 7th online edition of the journal Conservation Biology, the paper says that if we are to conserve significant wild populations of elephants across all regions ...

PITTSBURGH—Computer scientists at Carnegie Mellon University have designed a way to safely use multiple programming languages within the same program, enabling programmers to use the language most appropriate for each function while guarding against code injection attacks, one of the most severe security threats in Web applications today. A research group led by Jonathan Aldrich, associate professor in the Institute for Software Research (ISR), is developing a programming language called Wyvern that makes it possible to construct programs using a variety of targeted, ...

HOUSTON – (Aug. 7, 2014) – The stock prices of companies that use the same lead underwriter during their equity offerings tend to move together, according to a new study by financial economics experts at Rice University and the University of Alabama. "We tested the hypothesis that investment banking networks affect stock prices and trading behavior," said James Weston, a professor of finance at Rice's Jones Graduate School of Business. "Consistent with the notion that investment banks such as Goldman Sachs and Merrill Lynch serve as information hubs for segmented groups ...

PITTSBURGH, Aug. 7, 2014 – People who develop depression and mild cognitive impairment (MCI) after age 65 are more likely to have biological and brain imaging markers that reflect a greater vulnerability for accelerated brain aging, according to a study conducted by researchers at the University of Pittsburgh School of Medicine. The findings were published online in Molecular Psychiatry. Older adults with major depression have double the risk of developing dementia in the future compared with those who have never had the mood disorder, said senior investigator Meryl A. ...

Researchers with The Cancer Genome Atlas (TCGA) Research Network have completed the largest, most diverse tumor genetic analysis ever conducted, revealing a new approach to classifying cancers. The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill and other TCGA sites, not only revamps traditional ideas of how cancers are diagnosed and treated, but could also have a profound impact on the future landscape of drug development. "We found that one in 10 cancers analyzed in this study would be classified ...

WASHINGTON – Physically fit sixth-graders – especially girls – are less likely to report feeling depressed when they reach seventh grade, according to a study presented at the American Psychological Association's 122nd Annual Convention. Even when researchers considered existing symptoms of depression and weight, sixth-grade girls who performed better on a cardiorespiratory fitness test were less likely to feel depressed when they were surveyed again in seventh grade. There was a smaller but similar effect on boys' depression, according to the findings presented by Camilo ...

MADISON, Wis. — A fundamental chemical pathway that all plants use to create an essential amino acid needed by all animals to make proteins has now been traced to two groups of ancient bacteria. The pathway is also known for making hundreds of chemicals, including a compound that makes wood strong and the pigments that make red wine red. "We have been trying to unravel the source of the phenylalanine amino acid for some time," says Hiroshi Maeda, an assistant professor of botany at the University of Wisconsin-Madison. "Plants use this pathway to make natural products ...

CHAMPAIGN, Ill. — Cancer cells that break away from tumors to go looking for a new home may prefer to settle into a soft bed, according to new findings from researchers at the University of Illinois. Some particularly enterprising cancer cells can cause a cancer to spread to other organs, called metastasis, or evade treatment to resurface after a patient is thought to be in remission. The Illinois team, along with colleagues in China, found that these so-called tumor-repopulating cells may lurk quietly in stiffer cellular environments, but thrive in a softer space. The ...

Rising temperatures may be seen as universally beneficial for non-native species expanding northward, but a Dartmouth College study suggests a warmer world may help some invaders but hurt others depending on how they and native enemies and competitors respond. The study, which sheds light on the uncertain relationship between climate change and invasive species, appears in the journal Ecology. A PDF of the study is available on request. Climate change and invasive species rank among the largest predicted threats to global ecosystems over the next century, but they are ...

At least one part of the human brain may be able to process information the same way in older age as it does in the prime of life, according to new research conducted at the University of Adelaide. A study compared the ability of 60 older and younger people to respond to visual and non-visual stimuli in order to measure their "spatial attention" skills. Spatial attention is critical for many aspects of life, from driving, to walking, to picking up and using objects. "Our studies have found that older and younger adults perform in a similar way on a range of visual ...

Dimethyl fumarate (trade name: Tecfidera) has been approved since January 2014 for adults with relapsing remitting multiple sclerosis (RRMS). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) has examined whether this new drug for MS offers an added benefit over the appropriate comparator therapy specified by the Federal Joint Committee (G-BA). However, no added benefit can be determined, as no suitable data are available, neither for the direct ...

AUDIO: Washington University scientists have developed a method to grow human intestinal epithelial cells from tiny biopsies that are collected from patients during routine screening procedures like colonoscopies. They say the... Click here for more information. A method of growing human cells from tissue removed from a patient's gastrointestinal (GI) tract eventually may help scientists develop tailor-made therapies for inflammatory bowel disease and other GI conditions. Reporting ...

LAWRENCE — Recently, Malaysian herpetologist Juliana Senawi puzzled over an unfamiliar orange-striped, yellow-speckled frog she'd live-caught in swampland on the Malay Peninsula. She showed the frog to Chan Kin Onn, a fellow herpetologist pursuing his doctorate at the University of Kansas. They wondered — was this striking frog with an appearance unlike others nearby in the central peninsula an unidentified species? Poring over records to find out, the researchers saw that a comparable frog had been collected in the area 10 years earlier, but written off then as a ...

Weight loss significantly improves physical health but effects on mental health are less straightforward, finds new UCL research funded by Cancer Research UK. In a study of 1,979 overweight and obese adults in the UK, people who lost 5% or more of their initial body weight over four years showed significant changes in markers of physical health, but were more likely to report depressed mood than those who stayed within 5% of their original weight. The research, published in PLOS ONE, highlights the need to consider mental health alongside physical health when losing ...

Vision and hearing problems reduce the active participation of older people in various events and activities. This was observed in two studies carried out by the Gerontology Research Center. Impaired vision and hearing make it difficult to interact in social situations. However, social relationships and situations in which there is an opportunity to meet and interact with other people are important for older adults' quality of life. – Sensory impairments are common among older adults. About one third of Europeans aged 50 and older were found to have impairment in hearing, ...

NASA's Terra satellite grabbed a look at Typhoon Halong as it was nearing the Japanese islands of Minamidaito and Kitadaito and headed for a landfall in the main islands of southern Japan. The MODIS (Moderate Resolution Imaging Spectroradiometer) instrument aboard NASA's Terra satellite captured a visible image of Typhoon Halong on August 7 at 02:35 UTC, as it continued approaching southern Japan. The image showed thunderstorms tightly wrapped around the center of circulation. In addition there was a large, thick band of thunderstorms that wrapped into the center from ...

Boston, MA – New research from Brigham and Women's Hospital (BWH) finds that higher caffeine intake is associated with lower rates of tinnitus, often described as a ringing or buzzing sound in the ear when there is no outside source of the sounds, in younger and middle-aged women. This research is published in the August issue of the American Journal of Medicine. In this prospective study, which followed more than 65,000 women in the Nurses' Health Study II, researchers tracked self-reported results regarding lifestyle and medical history from these women, aged 30 to ...

HOUSTON – (August 7, 2014) – The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease – linked to the consumption of infected cattle meat – has been detected in the urine of patients with the disease by researchers at The University of Texas Health Science Center at Houston (UTHealth) Medical School. The results of the international study, led by Claudio Soto, Ph.D., professor of neurology at the UTHealth Medical School, are published in the Aug. 7 issue of the New England Journal of Medicine. Variant Creutzfeldt-Jakob disease ...

According to a study published in the journal Conservation Biology by a group of scientists from the University of Notre Dame, Resources for the Future, U.S. Forest Service, University of Michigan and the NOAA Great Lakes Environmental Laboratory, if bighead and silver carp were to establish in Lake Erie, local fish biomass is not likely to change beyond observations recorded in the last 3 decades. "Bighead and silver carp will continue to have access to the Great Lakes— it is important understand what the consequences could be if they were to establish" Marion ...

EAST LANSING, Mich. — Women applying for a job in male-dominated fields should consider playing up their masculine qualities, indicates new research by Michigan State University scholars that's part of a series of studies on bias in the hiring process. In a laboratory experiment, women who described themselves using masculine-like traits (assertive, independent, achievement oriented) were evaluated as more fitting for the job than those who emphasized female-like traits (warmth, supportiveness, nurturing). "We found that 'manning up' seemed to be an effective strategy, ...

Numerous risk factors are believed to contribute to the development of autoimmune disorders such as multiple sclerosis, and new research is focusing on the role that bacteria in the gastrointestinal tract as well as other cell stress-related chemical signals could have in stimulating inflammation in the central nervous system and activating immunostimulatory cytokines. Two comprehensive Review articles are part of a focus on "Cytokines in Neuroinflammation and Immunity" in a special issue of Journal of Interferon & Cytokine Research (JICR), a peer-reviewed publication from ...

A visible satellite image from NOAA's GOES-East satellite shows that Post-Tropical Storm Bertha was merging with a frontal system in the North Atlantic Ocean. The visible image from 1200 UTC (8 a.m. EDT) on August 6 was created at the NASA GOES Project, located at NASA's Goddard Space Flight Center in Greenbelt, Maryland. The image was created from data from NOAA's GOES-East satellite and the circulation center of Bertha is barely discernable. Bertha's circulation was connected to a stationary front that stretched from northeastern Canada to the Bahamas creating what ...

The adult CNS is remarkably adaptable – it retains the ability to generate and integrate new cells, and remodel pre-existing circuits. Intense research over the last 25 years has provided critical insight into the cell generation and differentiation potential of endogenous neural stem and progenitor cells, and has described three core CNS plasticity mechanisms. While we are still a long way from fully understanding how neural plasticity is regulated from the level of the individual cell, through to the level of the neural network, there is growing evidence to support the ...