Glioma is a common name for serious brain tumours. Different types of glioma are usually diagnosed as separate diseases and have been considered to arise from different cell types in the brain. Now researchers at Uppsala University, together with American colleagues, have shown that one and the same cell of origin can give rise to different types of glioma. This is important for the basic understanding of how these tumours are formed and can contribute to the development of more efficient and specific glioma therapies. The results have been published in Journal of Neuroscience. The ...

AMHERST, Mass. – Binge drinking can have lasting effects on brain pathways that are still developing during adolescence, say neuroscience researcher Heather N. Richardson and her colleagues at the University of Massachusetts Amherst and Louisiana State University. Results of their study using a rodent model of adolescent drinking appear in the October 29 issue of The Journal of Neuroscience. Richardson says, "Adverse effects of this physical damage can persist long after adolescent drinking ends. We found that the effects of alcohol are enduring." She adds, "The ...

WASHINGTON, DC — Heavy drinking during adolescence may lead to structural changes in the brain and memory deficits that persist into adulthood, according to an animal study published October 29 in The Journal of Neuroscience. The study found that, even as adults, rats given daily access to alcohol during adolescence had reduced levels of myelin — the fatty coating on nerve fibers that accelerates the transmission of electrical signals between neurons. These changes were observed in a brain region important in reasoning and decision-making. Animals that were ...

NASA's Lunar Reconnaissance Orbiter (LRO) spacecraft has spied a new crater on the lunar surface; one made from the impact of NASA's Lunar Atmosphere and Dust Environment Explorer (LADEE) mission. "The Lunar Reconnaissance Orbiter Camera (LROC) team recently developed a new computer tool to search Narrow Angle Camera (NAC) before and after image pairs for new craters, the LADEE impact event provided a fun test, said Mark Robinson, LROC principal investigator from Arizona State University in Tempe. "As it turns there were several small surface changes found in the predicted ...

How does a normal cellular process derail and become unhealthy? A multi-institutional, international team led by Virginia Tech researchers studied cells found in breast and other types of connective tissue and discovered new information about cell transitions that take place during wound healing and cancer. The results were published in a September issue of the journal Science Signaling. During development, cells change forms and regroup from tight packs of epithelial cells to more mobile, loose arrays of mesenchymal cells. The cell changes, known as an epithelial ...

Montreal, October 28, 2014 – The Montreal Heart Institute Research Centre is once again pushing the limits of knowledge in personalized medicine. A meta-analysis combining the results of several pharmacogenomic studies and involving over 40,000 research subjects now makes it possible to demonstrate a different response to statins according to the patient's gene profile. This important contribution of two Montreal researchers from the Montreal Heart Institute (MHI), Dr. Jean-Claude Tardif, Director of the Research Centre and Dr. Marie-Pierre Dubé, Director of ...

Fewer women than men are treated with dialysis for end-stage kidney disease, according to a new comprehensive analysis of sex-specific differences in treatment published this week in PLOS Medicine. The results of the study, conducted by Manfred Hecking with Friedrich Port and colleagues from Arbor Research Collaborative for Health in Ann Arbor, Michigan, suggest that these findings call for further detailed study for the reasons underlying the sex-specific differences in end-stage renal disease treatment. Chronic kidney disease often progresses to end-stage renal disease, ...

SAN FRANCISCO: A simple intervention designed to raise awareness about the use of communication devices while driving reduced the incidence of distracted driving by 50 percent in hospital personnel, according to findings from a single site study presented today at the 2014 Clinical Congress of the American College of Surgeons. Driving distracted–caused by any activity that steals a driver's attention from the road–is at an all-time high. In 2012, an estimated 421,000 people were injured in accidents involving distracted driving and 3,328 were killed as a result ...

A population of endangered giant tortoises, which once dwindled to just over a dozen, has recovered on the Galapagos island of Española, a finding described as "a true story of success and hope in conservation" by the lead author of a study published today (Oct. 28). Some 40 years after the first captive-bred tortoises were reintroduced to the island by the Galapagos National Park Service, the endemic Española giant tortoises are reproducing and restoring some of the ecological damage caused by feral goats that were brought to the island in the late 19th century. ...

New Haven, CT, Oct. 28 2014 – Each year, malaria kills over 600,000 people, more than half of them children. In a study published today in PLOS ONE , researchers with the non-profit Innovations for Poverty Action (IPA) and Harvard University found that simple text message reminders to take malaria medication can help in the fight against the disease by boosting the rates at which patients complete their medication regimen. One challenge in fighting malaria is that the disease has evolved resistance to many drugs that formerly worked, according to Julia Raifman, ...

This news release is available in German. In addition to their song, songbirds also have an extensive repertoire of calls. While the species-specific song must be learned as a young bird, most calls are, as in the case of all other birds, innate. Researchers at the Max Planck Institute in Seewiesen have now discovered that in zebra finches the song control system in the brain is also active during simple communication calls. This relationship between unlearned calls and an area of the brain responsible for learned vocalisations is important for understanding the ...

JUPITER, FL, October 28, 2014 – Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a major contributor to Huntington's disease, a devastating progressive neurological condition that produces involuntary movements, emotional disturbance and cognitive impairment. Using an animal model of Huntington's disease, the new study shows that signaling by a specific protein can trigger onset of the disease and lead to exacerbation of symptoms. These findings, published in the October 28, 2014 issue of the journal Science Signaling, offer ...

A connection between inflammation and cancer has been recognized for over a hundred years. This connection is particularly evident in colon carcinogenesis, because patients with IBD have a higher incidence of colon cancer than the general population. There is increasing evidence that inflammation contributes to the earliest stages of carcinogenesis, namely in the process of cell transformation, where the cell acquires many aspects of cancer characteristics. The observation that IBD and colon cancer incidence rise as nations industrialize suggests that changes in diet and ...

PROVIDENCE, R.I. [Brown University] — New research by physicists from Brown University puts the profound strangeness of quantum mechanics in a nutshell — or, more accurately, in a helium bubble. Experiments led by Humphrey Maris, professor of physics at Brown, suggest that the quantum state of an electron — the electron's wave function — can be shattered into pieces and those pieces can be trapped in tiny bubbles of liquid helium. To be clear, the researchers are not saying that the electron can be broken apart. Electrons are elementary particles, ...

Politics can have unintentional evolutionary consequences that may cause hastily issued policies to cascade into global, multigenerational problems, according to political scientists. "Most western democracies look at policies as if they are bandages, we fix what we can and then move on," said Pete Hatemi, associate professor of political science, Penn State. "But we need to consider generational policies so that we can fix what we can now, but also be prepared for what comes next." The researchers said that there is an interaction between political and cultural forces ...

WASHINGTON, D.C., October 28, 2014 – In the future, computers may be capable of talking to us during meetings just like a remote teleconference participant. But to help move this science-fiction-sounding goal a step closer to reality, it's first necessary to teach computers to recognize not only the words we use but also the myriad meanings, subtleties and attitudes they can convey. During the 168th Meeting of the Acoustical Society of America (ASA), to be held October 27-31, 2014, at the Indianapolis Marriott Downtown Hotel, Valerie Freeman, a Ph.D. candidate in ...

One of the tragic realities of cancer is that the drugs used to treat it are highly toxic and their effectiveness varies unpredictably from patient to patient. However, a new "tumor-in-a-dish" technology is poised to change this reality by rapidly assessing how effective specific anti-cancer cocktails will be on an individual's cancer before chemotherapy begins. A team of biomedical engineers at Vanderbilt University headed by Assistant Professor Melissa Skala has developed the technique, which uses fluorescence imaging to monitor the response of three-dimensional chunks ...

Tropical Cyclone Nilofar developed an eye on Oct. 28 that seemed to stare at NASA's Terra satellite as it passed overhead in space. Warnings are already in effect from the India Meteorological Department as Nilofar is forecast to make landfall in northwestern India. On Oct. 28 at 06:50 UTC (2:50 a.m. EDT) the MODIS instrument aboard Terra captured a visible image of Tropical Cyclone Nilofar after it developed an eye while moving north in the Arabian Sea. The 12 nautical mile (13.8 miles/22.2 km) wide eye was surrounded by powerful thunderstorms and bands of thunderstorms ...

DEET has been the gold standard of insect repellents for more than six decades, and now researchers led by a University of California, Davis, scientist have discovered the exact odorant receptor that repels them. They also have identified a plant defensive compound that might mimic DEET, a discovery that could pave the way for better and more affordable insect repellents. Findings from the study appear in the journal Proceedings of the National Academy of Sciences. More than 200 million people worldwide use DEET, developed by scientists at the U.S. Department of Agriculture ...

Nitrogen is an essential component of all living systems, playing important roles in everything from proteins and nucleic acids to vitamins. It is the most abundant element in Earth's atmosphere and is literally all around us, but in its gaseous state, N2,, it is inert and useless to most organisms. Something has to convert, or "fix," that nitrogen into a metabolically usable form, such as ammonia. Until about 100 years ago when an industrial-scale technique called the Haber-Bosch process was developed, bacteria were almost wholly responsible for all nitrogen fixation on ...

Boulder, Colo., USA - Mountain glaciers represent one of the largest repositories of fresh water in alpine regions. However, little is known about the processes by which water moves through these systems. In this study published in Geology on 24 Oct. 2014, David S. Heeszel and colleagues use seismic recordings collected near Lake Gornersee in the Swiss Alps to look for signs of water moving through fractures near the glacier bed. Analysis of these recordings reveals, for the first time, that harmonic tremor occurs within mountain glaciers and that individual icequakes at ...

BEER-SHEVA, Israel, October 28, 2014... A lack of sufficient punishment for deception facilitates "flopping" in basketball, according to new research from Ben-Gurion University of the Negev (BGU), which revealed that two-thirds of the falls were found to be intentional. Based on the research, the authors believe that players and teams are unaware of the cost/benefit analysis of "flopping" or the negative effect of falling if no offensive foul is awarded, which is indeed the case 90 percent of the time. In the study, published recently in the Journal of Economic Behavior ...

Farmland is vanishing in part because the salinity in the soil is rising as a result of climate change and other man-made phenomena. In an Opinion piece publishing in the Cell Press journal Trends in Plant Sciences, researchers propose a new concept for breeding salt- tolerant plants as a way to contribute to global efforts for sustainable food production. "We suggest that we should learn from nature and do what halophytes, or naturally salt-loving plants, are doing: taking up salt but depositing it in a safe place—external balloon-like structures called salt bladders," ...

A large analysis of over 40,000 individuals on statin treatment has identified two new genetic variants which influence how 'bad' cholesterol levels respond to statin therapy. Statins are widely prescribed to patients and have been shown to lower bad cholesterol levels by up to 55%, making them a highly effective method of reducing risk of heart disease. However, despite this success, patient response can vary widely. The study, led by Queen Mary University of London and published in Nature Communications, is the largest to date and involved analysing data from six ...

We're more likely to punish wrongdoing as a third party to a non-violent offense than when we're victimized by it, according to a new study by New York University psychology researchers. The findings, which appear in the journal Nature Communications, may offer insights into how juries differ from plaintiffs in seeking to restore justice. Their study, conducted in the laboratory of NYU Professor Elizabeth Phelps, also shows that victims, rather than seeking to punish an offender, instead seek to restore what they've lost. "In our legal system, individuals are presented ...