Parts of the primordial soup in which life arose have been maintained in our cells today according to scientists at the University of East Anglia. Research published today in the Journal of Biological Chemistry reveals how cells in plants, yeast and very likely also in animals still perform ancient reactions thought to have been responsible for the origin of life – some four billion years ago. The primordial soup theory suggests that life began in a pond or ocean as a result of the combination of metals, gases from the atmosphere and some form of energy, such as a lightning ...

Insecticides similar to nicotine, known as neonicotinoids, were found commonly in streams throughout the Midwest, according to a new USGS study. This is the first broad-scale investigation of neonicotinoid insecticides in the Midwestern United States and one of the first conducted within the United States. Effective in killing a broad range of insect pests, use of neonicotinoid insecticides has dramatically increased over the last decade across the United States, particularly in the Midwest. The use of clothianidin, one of the chemicals studied, on corn in Iowa alone ...

New York, NY - July 24, 2014 -- Keryx Biopharmaceuticals, Inc. (Nasdaq:KERX) (the "Company") announced the publication of results from the long-term, randomized, active control Phase 3 study of Zerenex (ferric citrate), the Company's investigational oral ferric iron-based phosphate binder, for the treatment of hyperphosphatemia in patients with end-stage renal disease (ESRD) on dialysis. The PERFECTED study (PhosphatE binding and iRon delivery with FErric CiTrate in EsrD) was published online today in the Journal of the American Society of Nephrology (JASN). This Phase ...

New research at the University of Adelaide has opened the way for the development of new lines of barley with resistance to powdery mildew. In Australia, annual barley production is second only to wheat with 7-8 million tonnes a year. Powdery mildew is one of the most important diseases of barley. Senior Research Scientist Dr Alan Little and team have discovered the composition of special growths on the cell walls of barley plants that block the penetration of the fungus into the leaf. The research, by the ARC Centre of Excellence in Plant Cell Walls in the University's ...

Neuregulin 1 (NRG1) is a pleiotropic factor characterized by the existence of numerous isoforms arising from alternative splicing of exons that confer to the protein deeply different characteristics. NRG1 plays an important role for both the myelination occurring during development and the different phases occurring after injury in the peripheral nerve: axon degeneration, axon regrowth, remyelination and target reinnervation Researchers at the University of Western Australia have discovered that the soluble NRG1 upregulation observed in Schwann cells immediately after ...

Spina bifda (SB) is a complex congenital central nervous system disease that is caused by the incomplete closing of the neural tubes during the embryonic phase. Many patients have varying degrees of spasticity, urinary and fecal incontinence and neurocognitive retardation. Such problems decrease the patients' functional independence and their quality of life. Researchers at Ankara Physical Medicine and Rehabilitation Education and Research Hospital, Turkey investigate the functional performance in children with SB, using the Pediatric Evaluation of Disability Inventory ...

After development of diffusion tensor tractography (DTT), which is derived from diffusion tensor imaging (DTI), three-dimensional reconstruction and estimation for three motor tracts, such as the corticospinal tract, the rubrospinal tract, and the corticoreticular pathway became possible. The corticospinal tract is known to be a major neural tract for motor function in the human brain. Several studies have reported on injury of the corticospinal tract by transtentorial herniation. In addition, some studies have demonstrated recovery of a corticospinal tract injured by transtentorial ...

For the first time, Spanish researchers have detected an unknown interaction between microorganisms and salt. When Escherichia coli cells are introduced into a droplet of salt water and is left to dry, bacteria manipulate the sodium chloride crystallisation to create biomineralogical biosaline 3D morphologically complex formations, where they hibernate. Afterwards, simply by rehydrating the material, bacteria are revived. The discovery was made by chance with a home microscope, but it made the cover of the Astrobiology journal and may help to find signs of life on other ...

A new study by researchers from the University of Leicester has furthered our understanding of how tiny nanosystems function, unlocking the potential to create new materials using nanosized 'building blocks'. The study, which has been published in the prestigious academic journal Physical Review Letters, used a novel laser technique to examine in rich detail the structure and internal atomic motion of a small cluster containing an acetylene molecule and a single helium atom. The technique excited single clusters and generated rotational wavepackets, which are composed ...

The National Institute for Fusion Science (NIFS), of the National Institutes of Natural Sciences (NINS) in Japan, has achieved an electrical current of 100,000 amperes, which is by far the highest in the world, by using the new idea of assembling the state-of-the-art yttrium-based high-temperature superconducting tapes to fabricate a large-scale magnet conductor. NIFS is undertaking the development of a high-temperature superconducting coil that is appropriate for the fusion reactor magnet. Using the state-of-the-art yttrium-based high-temperature superconducting tapes ...

There have been numerous cases of cultural changes throughout history. Either by imposition or assimilation, cultural traits are transmitted between neighbouring regions and often one replaces the original cultural traits of the other. Physicists Joaquim Fort, from the University of Girona (UdG), and Neus Isern, from the Universitat Autònoma de Barcelona (UAB), are experts in modelling these phenomena by adequately representing a reality, as they have demonstrated with their previous projects. In this occasion, the researchers applied their expertise to the area of language ...

Much artificial-intelligence research addresses the problem of making predictions based on large data sets. An obvious example is the recommendation engines at retail sites like Amazon and Netflix. But some types of data are harder to collect than online click histories —information about geological formations thousands of feet underground, for instance. And in other applications — such as trying to predict the path of a storm — there may just not be enough time to crunch all the available data. Dan Levine, an MIT graduate student in aeronautics and astronautics, and ...

BOSTON—A novel study shows that the age girls reach puberty is influenced by 'imprinted genes'—a subset of genes whose activity differs depending on which parent contributes the gene. This is the first evidence that imprinted genes can control the rate of development after birth and details of this study were published today in the journal Nature. Age of the first period, known as menarche, is a marker for the timing of puberty in females. Medical evidence shows that the onset of menses varies between girls, is an inherited trait, and is linked to breast cancer, diabetes ...

KANSAS CITY, MO—Researchers at the Stowers Institute for Medical Research have identified the functions of two classes of pheromone receptors, and found pheromones crucial to triggering the mating process in mice. They found one class of receptors helps a male mouse detect pheromones that indicate when a female is present. The other class of receptors lets him know if the female mouse is ovulating and ready to mate. Both sets of pheromones are critical to trigger mating. Stowers' researchers believe mice developed this system through evolution to maximize the chance of ...

Early life experiences, such as childhood socioeconomic status and literacy, may have greater influence on the risk of cognitive impairment late in life than such demographic characteristics as race and ethnicity, a large study by researchers with the UC Davis Alzheimer's Disease Center and the University of Victoria, Canada, has found. "Declining cognitive function in older adults is a major personal and public health concern," said Bruce Reed, professor of neurology and associate director of the UC Davis Alzheimer's Disease Center. "But not all people lose cognitive ...

People's emotional reactions and desires in initial romantic encounters determine the fate of a potential relationship. Responsiveness may be one of those initial "sparks" necessary to fuel sexual desire and land a second date. However, it may not be a desirable trait for both men and women on a first date. Does responsiveness increase sexual desire in the other person? Do men perceive responsive women as more attractive, and does the same hold true for women's perceptions of men? A study published in Personality and Social Psychology Bulletin seeks to answer those questions. ...

Heart attack patients could be treated more quickly after Manchester research Clinical judgement, combined with an electrocardiogram (ECG) and blood test on arrival, is effective in reducing unnecessary hospital admissions for chest pain, a new study shows. The findings of a research group in Manchester, published in the Emergency Medicine Journal, could potentially make a huge difference to a large number of patients. Chest pain is the most common reason for emergency hospital admission. In Manchester, the incidence of premature death due to heart disease and stroke ...

PITTSBURGH -- The routine use of a molecular testing panel developed at UPMC greatly increases the likelihood of performing the correct initial surgery for patients with thyroid nodules and cancer, report researchers from the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter. The test, available at the UPMC/UPCI Multidisciplinary Thyroid Center and other diagnostic testing agencies, improved the chances of patients getting the correct initial surgery by 30 percent, according to the study published this month in the Annals of Surgery. "Before ...

Today, nearly 700,000 people in the U.S. are living with a brain tumor, and yet, when it comes to pinpointing causes or risk factors, scientists are still searching for answers. "Right now, we don't know who, we don't know when, and we don't know why people develop brain tumors," said Elizabeth M. Wilson, MNA, President and CEO, American Brain Tumor Association. "It's frustrating for the brain tumor community, and it's why the American Brain Tumor Association funds research to pursue answers to these questions, and it's why we host this national conference to provide ...

The European Society for Medical Oncology (ESMO), the leading pan-European association representing medical oncology professionals, has expressed concern that the proposed EU General Data Protection Regulation [1] could make cancer research impossible and add a significant burden to both doctors and cancer patients. The proposed wording of the regulation [2] stipulates 'explicit and specific patient consent', meaning that researchers would have to approach patients every single time research is planned in order to consult their data or use tissue samples stored for research ...

PROVIDENCE, R.I. [Brown University] — The U.S. Preventive Services Task Force recently recommended computerized tomography (CT) lung screening for people at high risk for cancer, but a potential problem with CT is that many patients will have positive results on the screening test, only to be deemed cancer-free on further testing. Many policymakers have expressed concern that this high false-positive rate will cause patients to become needlessly upset. A new study of National Lung Screening Trial participant responses to false positive diagnoses, however, finds that those ...

PHILADELPHIA — For rats bearing human breast tumors, exposure to dim light at night made the tumors resistant to the breast cancer drug tamoxifen, according to data published in Cancer Research, a journal of the American Association for Cancer Research. The negative effects of dim light exposure on tamoxifen treatment were overcome by giving rats a melatonin supplement during the night. "Resistance to tamoxifen is a growing problem among patients with hormone receptor-positive breast cancer," said Steven M. Hill, PhD, professor of structural and cellular biology and the ...

Exposure to light at night, which shuts off nighttime production of the hormone melatonin, renders breast cancer completely resistant to tamoxifen, a widely used breast cancer drug, says a new study by Tulane University School of Medicine cancer researchers. The study, "Circadian and Melatonin Disruption by Exposure to Light at Night Drives Intrinsic Resistance to Tamoxifen Therapy in Breast Cancer," published in the journal Cancer Research, is the first to show that melatonin is vital to the success of tamoxifen in treating breast cancer. Principal investigators and ...

New York, NY - July 24, 2014 -- Keryx Biopharmaceuticals, Inc. (Nasdaq:KERX) (the "Company") announced the publication of results from the long-term, randomized, active control Phase 3 study of Zerenex (ferric citrate), the Company's investigational oral ferric iron-based phosphate binder, for the treatment of hyperphosphatemia in patients with end-stage renal disease (ESRD) on dialysis. The PERFECTED study (PhosphatE binding and iRon delivery with FErric CiTrate in EsrD) was published online today in the Journal of the American Society of Nephrology (JASN). This Phase ...

MIAMI – A new study suggests that Saharan dust played a major role in the formation of the Bahamas islands. Researchers from the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science showed that iron-rich Saharan dust provides the nutrients necessary for specialized bacteria to produce the island chain's carbonate-based foundation. UM Rosenstiel School Lewis G. Weeks Professor Peter Swart and colleagues analyzed the concentrations of two trace elements characteristic of atmospheric dust – iron and manganese – in 270 seafloor samples collected along ...