New studies of ancient DNA are shifting scientists' ideas of how groups of people migrated across the globe and interacted with one another thousands of years ago. By comparing nine ancient genomes to those of modern humans, Howard Hughes Medical Institute (HHMI) scientists have shown that previously unrecognized groups contributed to the genetic mix now present in most modern-day Europeans. "There are at least three major, highly differentiated populations that have contributed substantial amounts of ancestry to almost everybody that has European ancestry today," says ...

In the 1970s, Jane Goodall's reports of chimpanzee violence caught the attention of a global audience. Since then, many people have compared chimpanzee intergroup aggression to primitive warfare and have argued that chimpanzee violence is an adaptive strategy that gives the perpetrators an edge. Others have argued that lethal aggression is the consequence of human activities such as provisioning (artificial feeding) by researchers or habitat destruction. A new study of the pattern of intergroup aggression in chimpanzees and their close relatives, bonobos (also called pygmy ...

Skeletal dysplasia is a group of rare diseases that afflict skeletal growth through abnormalities in bone and cartilage. Its onset hits at the fetal stage and is caused by genetic mutations. A mutation in the gene encoding fibroblast growth factor receptor 3 (FGFR3) has been associated with two types of skeletal dysplasia, thanatophoric dysplasia (TD), a skeletal dysplasia that cause serious respiratory problems at birth and is often lethal, and achondroplasia (ACH), which causes stunted growth and other complications throughout life. Several experimental treatments have ...

COLUMBUS, Ohio – Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus. In a new study, researchers developed a math model that can predict the progression from nephritis – kidney inflammation – to interstitial fibrosis, scarring in the kidney that current treatments cannot reverse. A kidney biopsy is the only existing way to reach a definitive diagnosis of the damage and its extent. The model could also be used to monitor the effectiveness of experimental treatments for inflammation ...

In an analysis of genetic information among more than 87,000 men, a global team of scientists says it has found 23 new genetic variants – common differences in the genetic code -- that increase a man's risk for prostate cancer. The so-called "meta-analysis," believed to be the largest of its kind, has revealed once hidden mutations among men in a broad array of ethnic groups comprising men of European, African, Japanese and Latino ancestry. The meta-analysis combined information from smaller studies, according to William B. Isaacs, Ph.D., a genetic scientist at the Brady ...

COLUMBIA, Mo. – Research has shown that most 18-month-olds learn an average of two to five new words a day; however, little is known about how children process information to learn new words as they move through the preschool years. In a new study, a University of Missouri researcher has found that toddlers learn words differently as they age, and a limit exists as to how many words they can learn each day. These findings could help parents enhance their children's vocabularies and assist speech-language professionals in developing and refining interventions to help children ...

Fauna Europaea started in 2000 as an EC-FP5 four-year project, delivering its first release in 2004. After 14 years of steady progress and successful participations in several EC projects, as a part of the EC-FP7 European Biodiversity Observation Network project (EU BON), to increase the general awareness of the work done by the contributors and to extend the general dissemination of the Fauna Europaea results, the Biodiversity Data Journal has applied its novel e-Publishing tools to prepare data papers for all 56 major taxonomic groups. Fauna Europaea provides a public ...

Astronomers using the NASA/ESA Hubble Space Telescope have found a monster lurking in a very unlikely place. New observations of the ultracompact dwarf galaxy M60-UCD1 have revealed a supermassive black hole at its heart, making this tiny galaxy the smallest ever found to host a supermassive black hole. This suggests that there may be many more supermassive black holes that we have missed, and tells us more about the formation of these incredibly dense galaxies. The results will be published in the journal Nature on 18 September 2014. Lying about 50 million light-years ...

SAN DIEGO, Calif. (Sept. 17, 2014)— A rare genetic disorder known as Jacobsen syndrome has been linked with autism, according to a recent joint investigation by researchers at San Diego State University and the University of California, San Diego. In addition to suggesting better treatment options for people with Jacobsen syndrome, the finding also offers more clues into the genetic underpinnings of autism. Jacobsen syndrome affects approximately 1 in 100,000 people, according to the National Institutes of Health. It occurs in a person when there is a deletion at the end ...

CORVALLIS, Ore. – People with facial paralysis are perceived as being less happy simply because they can't communicate in the universal language of facial expression, a new study from an Oregon State University psychology professor shows. The findings highlight the important role the face plays in everyday communication and indicates people may hold a prejudice against those with facial paralysis because of their disability, said Kathleen Bogart, an assistant professor of psychology in the College of Liberal Arts at Oregon State University. "People are more wary and ...

Leaving one's job to become an entrepreneur is inarguably risky. But it may not be the fear of risk that makes entrepreneurs more determined to succeed. A new study finds entrepreneurs are also concerned about what they might lose in the transition from steady employment to startup. In Entrepreneurship and Loss-Aversion in a Winner-Take-All Society, Professor John Morgan at UC Berkeley's Haas School of Business and co-author Dana Sisak, assistant professor at the Erasmus University Rotterdam, focused on the powerful impact of loss aversion. Loss aversion, or the fear ...

The quest for the ultimate memory device for computing may have just taken an encouraging step forward. Researchers at The City College of New York led by chemist Stephen O'Brien have discovered new complex oxides that exhibit both magnetic and ferroelectric properties. Combining both properties is very exciting scientifically for the coupling that can occur between them and for the devices that might ultimately be designed, in logic circuits or spintronics. Combining these two properties in a single material, however, has proved difficult until now. Using an innovative ...

Imagine being able to switch out the batteries in electric cars just like you switch out batteries in a photo camera or flashlight. A team of engineers at the University of California, San Diego, are trying to accomplish just that, in partnership with a local San Diego engineering company. They have developed smaller units within the battery, called modules, and a battery management system that will allow them to swap out and recharge the modules, rather than swapping out the whole battery, which is cumbersome and requires large, heavy equipment. They recently presented ...

WASHINGTON -- The U.S. health care system is not properly designed to meet the needs of patients nearing the end of life and those of their families, and major changes to the system are necessary, says a new report from the Institute of Medicine. The 21-member committee that wrote the report envisioned an approach to end-of-life care that integrates traditional medical care and social services and that is high-quality, affordable, and sustainable. The committee called for more "advance care planning" for end-of-life by individuals, for improved training and credentialing ...

CHICAGO --- The first blood test to diagnose major depression in adults has been developed by Northwestern Medicine® scientists, a breakthrough approach that provides the first objective, scientific diagnosis for depression. The test identifies depression by measuring the levels of nine RNA blood markers. RNA molecules are the messengers that interpret the DNA genetic code and carry out its instructions. The blood test also predicts who will benefit from cognitive behavioral therapy based on the behavior of some of the markers. This will provide the opportunity for more ...

A new study shows that patients with human papillomavirus (HPV) – the same virus associated with both cervical and head and neck cancer – positive oropharyngeal cancer see significantly higher rates of complete response on a post-radiation neck dissection than those with HPV-negative oropharyngeal cancer. Fox Chase Cancer Center researchers presented the findings at the American Society for Radiation Oncology's 56th Annual Meeting on Wednesday, September 17. "For patients that achieve a complete response, neck surgery is probably unnecessary," says Thomas J. Galloway, ...

Researchers at the Catalan Institute of Oncology-Bellvitge Biomedical Research Institute (ICO-IDIBELL), led by David Garcia-Molleví have identified 5 genes differentially expressed in normal accompanying cells in colorectal tumors. Analysis of these genes could be used to classify colorectal tumors, predict the evolution of the patient and thus take appropriate clinical decisions to prevent relapses. Biomarkers Colorectal cancer is the most common in our population considering both sexes. About 30,000 new cases are diagnosed each year. Of these, approximately 70% are ...

EAST LANSING, Mich. – Mutations in the human retinoblastoma protein gene are a leading cause of eye cancer. Now, Michigan State University scientists have turned to fruit fly eyes to unlock the secrets of this important cancer gene. In a paper featured on the cover of the current issue of the Journal of Biological Chemistry, Michigan State University researchers provide the first detailed examination of a set of mutations similar to those present in the human cancer gene, said Irina Pushel, MSU undergraduate and co-author. "By systematically evaluating mutations of ...

Researchers at Moffitt Cancer Center, including Center Director Thomas A. Sellers, Ph.D., M.P.H., Jong Park, Ph.D. and Hui-Yi Lin, Ph.D., have discovered 23 new regions of the genome that influence the risk for developing prostate cancer, according to a study published Sept. 14 in Nature Genetics. Prostate cancer is the most common non-skin cancer in American men. About 1 in 6 men will be diagnosed with the disease in his lifetime. Family history is the strongest risk factor. A man with one close relative, a brother or father with prostate cancer is twice as likely to ...

September 17, 2014 – People with bipolar disorder who do yoga believe their yoga practice has significant mental health benefits, reports a survey study in the September Journal of Psychiatric Practice. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. "Some individuals with bipolar disorder believe that yoga has had a significant positive impact on their life." according to the study by Dr Lisa A. Uebelacker of Butler Hospital and Brown University, Providence, R.I., and colleagues. But they note their survey shows that yoga ...

DALLAS – September 17, 2014 – Researchers at UT Southwestern Medical Center have found that the most common variant of the circulating protein apolipoprotein E, called apoE3, helps repair the lining of blood vessels. Individuals with another variant, called apoE4, do not get the benefit of this repair, putting them at higher risk for cardiovascular disease. "We believe that we have identified one mechanism by which apoE3 promotes a healthy cardiovascular system and why a genetic variant, apoE4, is detrimental," said Dr. Philip Shaul, Professor of Pediatrics and Vice Chair ...

The work comes out of the molecular therapeutic laboratory directed by Richard G. Moore, MD, of Women & Infants' Program in Women's Oncology. Entitled "HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocation," the research was recently published in the international science journal Scientific Reports, a Nature publishing group. The goal of the study was to investigate the role of the hormone HE4 in modulating an ovarian cancer's response to hormones and hormonal therapies. HE4 is a biomarker that is elevated in ovarian ...

Washington, DC— A team of researchers working on a Carnegie expedition in Australia's Great Barrier Reef has documented that coral growth rates have plummeted 40% since the mid-1970s. The scientists suggest that ocean acidification may be playing an important role in this perilous slowdown. In a quest for historical context on the peril facing coral reefs, the team compared current measurements of the growth rate of a section of Australia's Great Barrier Reef with similar measurements taken more than 30 years ago. Their work is published in Geochimica et Cosmochimica ...

A mathematical model that replicates Ebola outbreaks can no longer be used to ascertain the eventual scale of the current epidemic, finds research conducted by the University of Warwick. Dr Thomas House, of the University's Warwick Mathematics Institute, developed a model that incorporated data from past outbreaks that successfully replicated their eventual scale. The research, titled Epidemiological Dynamics of Ebola Outbreaks and published by eLife, shows that when applying the available data from the ongoing 2014 outbreak to the model that it is, according to Dr ...

Alexandria, Va. — Most people are familiar with the Great 1906 San Francisco Earthquake and are aware of the earthquake risk posed to the Bay Area — and much of California — by the San Andreas Fault. Most people are not aware, however, that a cluster of large earthquakes struck the San Andreas and quite a few nearby faults in the 17th and 18th centuries. That cluster, according to new research, released about the same amount of energy throughout the Bay Area as the 1906 quake. Thus, it appears that the accumulated stress on the region's faults could be released in a series ...