Rigid connections: Molecular basis of age-related memory loss explained
2014-07-22
From telephone numbers to foreign vocabulary, our brains hold a seemingly endless supply of information. However, as we are getting older, our ability to learn and remember new things declines. A team of scientists around Associate Prof Dr Antonio Del Sol Mesa from the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg and Dr Ronald van Kesteren of the VU University Amsterdam have identified the molecular mechanisms of this cognitive decline using latest high-throughput proteomics and statistical methods. The results were published this week in the ...
New water balance calculation for the Dead Sea
2014-07-22
This news release is available in French.
Tel Aviv/Halle, Saale. The drinking water resources on the eastern, Jordanian side of the Dead Sea could decline severe as a result of climate change than those on the western, Israeli and Palestinian side. This is the conclusion reached by an international team of researchers that calculated the water flows around the Dead Sea. The natural replenishment rate of groundwater will reduce dramatically in the future if precipitation lowers as predicted, say the scientists, writing in the journal Science of the Total Environment. ...
Novel methods may help stem cells survive transplantation into damaged tissues
2014-07-22
New Rochelle, NY -- Stem cells offer much promise for treating damaged organs and tissues, but with current transplantation approaches stem cell survival is poor, limiting their effectiveness. New methods are being developed and tested to improve the survival and optimize their therapeutic function after transplantation, as described in a Review article in BioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website.
In the article 'Preconditioning Stem Cells for In Vivo ...
Study compares cost-effectiveness of weight-loss programs and drugs
2014-07-22
DURHAM, N.C. – In a cost-effectiveness analysis of commercial diet programs and pills, the Weight Watchers program and the drug Qsymia showed the best value for the money. The Jenny Craig regimen generated the greatest weight loss, but was also the most expensive option tested, according to researchers at Duke-National University of Singapore (NUS) Graduate Medical School.
The findings, published in the June issue of the journal Obesity, provide important information on the health and weight-loss benefits per dollar spent as insurance carriers consider coverage for weight ...
The nostalgia effect: Do consumers spend more when thinking about the past?
2014-07-22
Say you are out clothes shopping and you spot something that brings you back to a special time from your childhood when you were surrounded by friends and family. Suddenly, you find yourself purchasing an expensive shirt that makes you feel like a kid again. According to a new study in the Journal of Consumer Research, we're more likely to spend money when we're feeling nostalgic.
"We wondered why nostalgia is so commonplace in marketing. One reason could be that feeling nostalgic weakens a person's desire for money. In other words, someone might be more likely to buy ...
Trying to get kids to eat healthier? Don't tell them veggies are good for them
2014-07-22
At some point, most kids will hear that drinking milk helps make their bones strong or that fish is food for the brain. But do these messages foster the idea that if something is good for us, it must surely taste bad? According to a new study in the Journal of Consumer Research, when children hear about the benefits of healthy food, they're less likely to eat it.
"We predicted that when food is presented to children as making them strong or as a tool to achieve a goal such as learning how to read or count, they would conclude the food is not as tasty and therefore consume ...
You deserve it! Are consumers more likely to buy unique products when made to feel special?
2014-07-22
Graduating from college is an important life event often attributed to being smart and working hard. Many people celebrate this milestone achievement by buying themselves an expensive gift or taking a dream vacation. A new study in the Journal of Consumer Research shows that consumers who attribute their successes to internal character traits rather than hard work are more likely to select unique products.
"We found that consumers who attribute feelings of pride to their unique character traits—rather than how hard they worked to accomplish something—are more likely to ...
HIF 1α viral vector inhibits hippocampal neuronal apoptosis: The future of gene therapy
2014-07-22
Hypoxia-inducible factor 1 (HIF-1) attenuates amyloid-beta protein neurotoxicity and decreases apoptosis induced by oxidative stress or hypoxia in cortical neurons. Prof. Xiqing Chai and co-workers from Hebei Chemical and Pharmaceutical College, China constructed a recombinant adeno-associated virus (rAAV) vector expressing the human HIF-1α gene (rAAV-HIF-1α) efficiently, and tested the assumption that rAAV-HIF-1α represses hippocampal neuronal apoptosis induced by amyloid-beta protein. Their results confirmed that rAAV-HIF-1α significantly reduces apoptosis ...
Acupuncture at the Taixi activates cerebral neurons in old patients with MCI
2014-07-22
Previous findings have demonstrated that acupuncture at the Taixi (KI3) acupoint in healthy youths can activate neurons in cognitive-related cerebral cortex. In a perspective article released in the Neural Regeneration Research (Vol. 9, No. 11, 2014), Dr. Shangjie Chen and co-workers at Baoan Hospital, Southern Medical University, China investigated whether acupuncture at this acupoint in elderly patients with mild cognitive impairment (MCI) can also activate neurons in these regions. Researchers revealed that under resting state and task-related functional magnetic resonance ...
X-ray irradiation at a certain dose alters the neuronal cytoskeleton and cytomechanics
2014-07-22
Cranial radiotherapy is one of the most important therapeutic methods for the treatment of various types of primary and metastatic brain tumors. Although conventional photon irradiation has significantly improved the treatment of cancer, the central nervous system is prone to damage after high-dose irradiation, resulting in severe delayed or progressive nervous tissue injury. The issues regarding brain radiation injury have been widely discussed, and recent investigations have emphasized changes in pathomorphology. However, the underlying mechanism remains in debate. Researchers ...
Self-cooling solar cells boost power, last longer
2014-07-22
WASHINGTON, July 22, 2014—Scientists may have overcome one of the major hurdles in developing high-efficiency, long-lasting solar cells—keeping them cool, even in the blistering heat of the noonday Sun.
By adding a specially patterned layer of silica glass to the surface of ordinary solar cells, a team of researchers led by Shanhui Fan, an electrical engineering professor at Stanford University in California has found a way to let solar cells cool themselves by shepherding away unwanted thermal radiation. The researchers describe their innovative design in the premiere ...
Major dopamine system helps restore consciousness after general anesthesia, study finds
2014-07-22
Chicago – July 22, 2014 – Researchers may be one step closer to better understanding how anesthesia works. A study in the August issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists® (ASA®), found stimulating a major dopamine-producing region in the brain, the ventral tegmental area (VTA), caused rats to wake from general anesthesia, suggesting that this region plays a key role in restoring consciousness after general anesthesia. Activating this region at the end of surgery could provide a novel approach to proactively induce ...
Creating optical cables out of thin air
2014-07-22
Imagine being able to instantaneously run an optical cable or fiber to any point on earth, or even into space. That's what Howard Milchberg, professor of physics and electrical and computer engineering at the University of Maryland, wants to do.
In a paper published today in the July 2014 issue of the journal Optica, Milchberg and his lab report using an "air waveguide" to enhance light signals collected from distant sources. These air waveguides could have many applications, including long-range laser communications, detecting pollution in the atmosphere, making high-resolution ...
Has Antarctic sea ice expansion been overestimated?
2014-07-22
New research suggests that Antarctic sea ice may not be expanding as fast as previously thought. A team of scientists say much of the increase measured for Southern Hemisphere sea ice could be due to a processing error in the satellite data. The findings are published today in The Cryosphere, a journal of the European Geosciences Union (EGU).
Arctic sea ice is retreating at a dramatic rate. In contrast, satellite observations suggest that sea ice cover in the Antarctic is expanding – albeit at a moderate rate – and that sea ice extent has reached record highs in recent ...
Mixed genes mix up the migrations of hybrid birds
2014-07-22
Mixed genes appear to drive hybrid birds to select more difficult routes than their parent species, according to new research from University of British Columbia zoologists.
"Instead of taking well-trodden paths through fertile areas, these birds choose to scale mountains and cross deserts," says UBC researcher Kira Delmore.
Delmore harnessed a flock of B.C. Swainson's thrushes with tiny geolocating backpacks to map their routes as they migrated south through the U.S. to Central and South America.
Many of the hybrid thrushes chose intermediary migration routes situated ...
New York squirrels are nuts about city life
2014-07-22
Curtin University-led research has shown squirrels have adapted to New York City's human behaviour, allowing them to thrive just as well, if not better, than their fellow squirrels in the woods.
Dr Bill Bateman, Senior Lecturer at Curtin's Department of Environment & Agriculture, led the study that proved eastern grey squirrels were able to modify their behaviour in urban environments and prevent unnecessary responses when humans acted in a predictable manner, such as staying on the footpath.
"As we rapidly increase the spread of urbanisation around the world, urban ...
LSUHSC contributes to work identifying new DNA regions associated with schizophrenia
2014-07-22
New Orleans, LA -- Nancy Buccola, MSN, APRN, PMHCNS-BC, CNE, Assistant Professor of Clinical Nursing at LSU Health Sciences Center New Orleans School of Nursing, contributed samples used in a study reporting new locations of genetic material associated with schizophrenia and also suggesting a possible link between the immune system and schizophrenia. The study, “Biological insights from 108 schizophrenia-associated genetic loci,” was published online July 22, 2014 in Nature, available at http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13595.html.
...
Natural-terrain schoolyards reduce children's stress, says Colorado University-Boulder study
2014-07-22
Playing in schoolyards that feature natural habitats and trees and not just asphalt and recreation equipment reduces children's stress and inattention, according to a University of Colorado Boulder study.
Working on class assignments or gardening in such settings also provide stress-reducing benefits for youth, according to a paper published in the journal Health & Place. The study is one of the first of its kind to focus on the relationship between student access to green settings and stress.
"Many schools already offer stress management programs, but they're about ...
African-American homeownership increasingly less stable and more risky
2014-07-22
While historical barriers that excluded Black America from the homeowner market for decades have crumbled, there are signs that emerging types of racial inequality are making homeownership an increasingly risky investment for African-American home seekers. A new study from sociologists at Rice University and Cornell University found that African-Americans are 45 percent more likely than whites to switch from owning their homes to renting them.
The study, "Emerging Forms of Racial Inequality in Homeownership Exit, 1968-2009," examines racial inequality in transitions out ...
Low strength brain stimulation may be effective for depression
2014-07-22
Philadelphia, PA -- Brain stimulation treatments, like electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS), are often effective for the treatment of depression. Like antidepressant medications, however, they typically have a delayed onset. For example, a patient may receive several weeks of regular ECT treatments before a full response is achieved.
Thus, there is an impetus to develop antidepressant treatments that act to rapidly improve mood.
Low field magnetic stimulation (LFMS) is one such potential new treatment with rapid mood-elevating ...
Boosting the force of empty space
2014-07-22
This news release is available in German.
Vacuum is not as empty as one might think. In fact, empty space is a bubbling soup of various virtual particles popping in and out of existence – a phenomenon called "vacuum fluctuations". Usually, such extremely short-lived particles remain completely unnoticed, but in certain cases vacuum forces can have a measurable effect. A team of researchers from the Weizmann Institute of Science (Rehovot, Israel) and the Vienna University of Technology has now proposed a method of amplifying these forces by several orders of magnitude ...
Anti-cancer drug kicks HIV out of hiding
2014-07-22
A pilot study by HIV researchers from Aarhus University and Aarhus University Hospital in Denmark has shown that an anti-cancer drug can activate hidden HIV. The researchers found that the anti-cancer drug romidepsin increased the virus production in HIV-infected cells between 2.1 and 3.9 times above normal and that the viral load in the blood increased to measurable levels in five out of six patients with HIV infection.
A pilot study
The results were presented today as breaking news at the annual international AIDS conference in Melbourne, Australia. The pilot study ...
Jeju Island is a live volcano
2014-07-22
In Jeju, a place emerging as a world-famous vacation spot with natural tourism resources, a recent study revealed a volcanic eruption occurred on the island. The Korea Institute of Geoscience and Mineral Resources (KIGAM) indicated that there are the traces that indicated that a recent volcanic eruption was evident 5,000 years ago. That is the first time to actually find out the date when lava spewed out of a volcano 5,000 years ago in the inland part of the island as well as the one the whole peninsula.
The research team led by Dr. Jin-Young Lee confirmed in results ...
Unique study focuses on combined treatment approach for locally advanced pancreatic cancer
2014-07-22
LOS ANGELES (July 21, 2014) – Investigators at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute are developing a novel, multistep investigational treatment for one of the most complex and difficult-to-treat forms of the disease, locally advanced pancreatic cancer.
Locally advanced pancreatic cancer has the lowest survival rate of any solid tumor, with a cumulative five-year survival rate of only 4 percent for all stages of disease. Surgery is rarely an option for patients because tumors often involve vital blood vessels. Chemotherapy and radiotherapy given ...
Vanderbilt discovery may advance colorectal cancer diagnosis and treatment
2014-07-22
A Vanderbilt University-led research team has identified protein "signatures" of genetic mutations that drive colorectal cancer, the nation's second leading cause of cancer deaths after lung cancer.
The technological tour de force, described in the current issue of the journal Nature as the first integrated "proteogenomic" characterization of human cancer, "will enable new advances" in diagnosing and treating the disease, the scientists concluded.
"It's a first-of-its-kind paper. I think it's a very important advance in the field," said senior author Daniel Liebler, ...
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