Group B Streptococcus breaches the blood-brain-barrier
Bacterial meningitis is a life-threating infection of the central nervous system. Group B Streptococcus (GBS) is the leading cause of meningitis in newborn babies and can cause severe complications in those that survive the infection. GBS must cross the blood-brain-barrier (BBB) to cause disease but it is not clear how these organisms breach this barrier. A new study in the Journal of Clinical Investigation identifies a pathway that is induced by GBS and disrupts junctions between cells. Kelly Doran and colleagues at San Diego State University determined that GBS induces ...







