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Medicine 2014-05-27

X-ray dark-field radiography provides detailed imaging of lung diseases

As the team reports in the Investigative Radiology journal, this method shows promise in detecting diseases such as pulmonary emphysema at an earlier stage, than it is currently available. Conventional radiographic procedures generate images based on the absorption of X-rays as they pass through the tissue. The newly developed technique of X-ray dark-field radiography uses new technology to monitor wave changes during tissue transmission to create higher resolution images. Detailed images With the aid of this new technique, the team from the HMGU, KUM and TUM around Dr. ...
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Medicine 2014-05-27

Two new possible drug targets for triple negative breast cancer

HOUSTON -- ( May 27, 2014 ) -- The suppression of two genes reduce breast cancer tumor formation and metastasis by interfering with blood vessel formation and recruitment, report scientists from Houston Methodist and five other institutions in the Proceedings of the National Academy of Sciences (now online). The findings may help medical researchers identify effective drug targets for triple negative breast cancer, or TNBC. The genes, MLF2 (myeloid leukemia factor 2) and RPL39 (a ribosomal protein), were found to most profoundly impact the production of nitric oxide synthase, ...
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Social Science 2014-05-27

Large numbers of shadow economy entrepreneurs in developing countries, according to new report

There are large numbers of entrepreneurs in developing countries who aren't registering their businesses with official authorities, hampering economic growth, according to new research. Shadow entrepreneurs are individuals who manage a business that sells legitimate goods and services but they do not register it. This means that they do not pay tax, operating in a shadow economy where business activities are performed outside the reach of government authorities. The shadow economy results in loss of tax revenue, unfair competition to registered businesses and also poor ...
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Science 2014-05-27

Mycotoxin protects against nematodes

This news release is available in German. Most terrestrial plants enter into biocoenosis with funghi. Both sides benefit: the fungus, which surrounds the small roots of the host plant with a thick felt, supplies the plant with trace elements and water. The plant, in turn, supplies the fungus with sugars and other metabolites which it is unable to produce itself. Toxic protein kills intestinal cells ETH researchers from the research group of microbiology professor Markus Aebi have discovered a protein in the cells of one such ectomycorrhizal fungus which offers an ...
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AGU: Experts publish new view of zone where Malaysia Airlines flight 370 might lie
Technology 2014-05-27

AGU: Experts publish new view of zone where Malaysia Airlines flight 370 might lie

WASHINGTON, D.C. -- A new illustration of the seafloor, created by two of the world's leading ocean floor mapping experts that details underwater terrain where the missing Malaysia Airlines flight might be located, could shed additional light on what type of underwater vehicles might be used to find the missing airplane and where any debris from the crash might lie. The seafloor topography map illustrates jagged plateaus, ridges and other underwater features of a large area underneath the Indian Ocean where search efforts have focused since contact with Malaysia Airlines ...
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Technology 2014-05-27

Rules to cut carbon emissions also reduce air pollution harmful to people, environment

(Syracuse, NY – May 27, 2014) Setting strong standards for climate-changing carbon emissions from power plants would provide an added bonus – reductions in other air pollutants that can make people sick; damage forests, crops, and lakes; and harm fish and wildlife. This, according to a first-of-its-kind study released today by scientists at Syracuse University and Harvard who mapped the potential environmental and human health benefits of power plant carbon standards. The authors of the new study, Co-benefits of Carbon Standards: Air Pollution Changes under Different ...
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Medicine 2014-05-27

Skin grafts from genetically modified pigs may offer alternative for burn treatment

A specially-bred strain of miniature swine lacking the molecule responsible for the rapid rejection of pig-to-primate organ transplants may provide a new source of skin grafts to treat seriously burned patients. A team of investigators from Massachusetts General Hospital (MGH) report that skin grafts from pigs lacking the Gal sugar molecule were as effective in covering burn-like injuries on the backs of baboons as skin taken from other baboons, a finding that could double the length of time burns can be protected while healing. The report in the journal Transplantation ...
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Science 2014-05-27

EuroPCR 2014 session defines future horizons for renal denervation

23 May 2014, Paris, France: During EuroPCR 2014, Felix Mahfoud, University Hospital in Homburg, Germany, and Konstantinos Tsioufis, University of Athens, Greece, reflected on the potential future role of modulation of the sympathetic nervous system in patients with difficult-to-control hypertension. In the context of the SYMPLICITY-HTN-3 clinical trial results, questions were raised about the extent of the procedure's efficacy although the randomised, controlled trial confirmed the safety of renal denervation. "In terms of efficacy, some studies have shown that renal ...
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New biodiversity study throws out controversial scientific theory
Environment 2014-05-27

New biodiversity study throws out controversial scientific theory

Researchers have today released ground-breaking findings that dismiss the 'Neutral Theory of Biodiversity'. The theory has dominated biodiversity research for the past decade, and been advocated as a tool for conservation and management efforts. Professor Sean Connolly from the ARC Centre of Excellence for Coral Reef Studies (Coral CoE) at James Cook University (JCU) is the lead author of the international study, which he says overturns the long-used theory by employing a novel mathematical method. It is the largest study of its kind, covering a broad range of marine ...
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Medicine 2014-05-27

Does apolipoprotein E mimetic peptide reduce neuronal apoptosis induced by DBI?

Because the majority of patients with diffuse brain injury are not suitable candidates for surgery, neuroprotective agents are of great importance. Apolipoprotein E exerts a neuroprotective effect against brain injury, but synthetic apolipoprotein E cannot cross the blood-brain barrier, thus limiting its application.It has been reported that apolipoprotein E (138) mimetic peptide can cross the blood-brain barrier in both normal and injured brain. However, its impact on neurological function following diffuse brain injury is still unclear. Prof. Jianmin Li and team from ...
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Medicine 2014-05-27

A novel disease-preventing antioxidant pathway

Interested in antioxidants? They protect us against aging and cancer. It's one of the reasons we like our green tea and even our broccoli. But there is a new kid on the antioxidant block - uric acid. But wait, you're thinking, doesn't uric acid cause gout? A team in Singapore has recently showed that uric acid is a major intracellular antioxidant, possibly even more important than the antioxidants we try to eat. They also discovered how uric acid helps to prevent aging and disease and how it helps in the treatment of cancer. Traditionally, uric acid has a bad reputation ...
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Medicine 2014-05-27

Immunologists discover immune system precursor cells that fight infection

The innate immune system recognizes infectious agents such as viruses and bacteria. A group of lymphocytes known as "innate lymphoid cells" or ILCs plays a central role in the defense of the human body against infective agents. Professor Andreas Diefenbach of the Research Center Immunology at the Mainz University Medical Center, working in collaboration with scientists at the University of Freiburg, has discovered previously unidentified ILCs that are able to protect epithelial surfaces, such as those of the intestinal mucosa, against infection. The results provide important ...
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Technology 2014-05-27

Using thoughts to control airplanes

The pilot is wearing a white cap with myriad attached cables. His gaze is concentrated on the runway ahead of him. All of a sudden the control stick starts to move, as if by magic. The airplane banks and then approaches straight on towards the runway. The position of the plane is corrected time and again until the landing gear gently touches down. During the entire maneuver the pilot touches neither pedals nor controls. This is not a scene from a science fiction movie, but rather the rendition of a test at the Institute for Flight System Dynamics of the Technische Universität ...
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Science 2014-05-27

Melatonin makes old bones stronger

Faleh Tamimi, a professor in McGill's School of Dentistry, is the leader of a research team that has just discovered that melatonin supplements make bones stronger in elderly rats and therefore, potentially, in elderly humans too. "Old rats are tedious to work with because they get sick a lot and that means they also cost a lot more. But if you're interested in diseases like osteoporosis, they're an essential part of the process." Dem bones, dem bones, dem dry bones – sleep and bone regulation The process of bone breakdown and buildup is affected by our circadian ...
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Intermediaries increase corruption
Science 2014-05-27

Intermediaries increase corruption

This news release is available in Spanish. In reality, an intermediary participates in many, if not most, cases of corruption. However there has been very scarce empirical evidence that illuminates their role in these situations. This is what a researcher at UC3M has analyzed in collaboration with scientists from Florida State University and Southern Methodist University, in Texas (both in the United States). The results of their study, recently published in Experimental Economics, confirm their suspicions: "Our work showed that the number of persons involved in cases ...
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Science 2014-05-27

Outgrowing emotional egocentricity

This news release is available in German. Children are more egocentric than adults. Scientists from the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig have demonstrated for the first time that children are also worse at putting themselves in other people's emotional shoes. According to the researchers, the supramarginal gyrus region of the brain must be sufficiently developed in children for them to be able to overcome their egocentric take on the world. When little Philip rejoices at winning the prize in a game, it is almost impossible for ...
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People attribute free will to mind, not soul
Science 2014-05-27

People attribute free will to mind, not soul

PROVIDENCE, R.I. [Brown University] — Across the board, even if they believed in the concept of a soul, people in a new study ascribed free will based on down-to-Earth criteria: Did the actor in question have the capacity to make an intentional and independent choice? The study suggests that while grand metaphysical views of the universe remain common, they have little to do with how people assess each other's behavior. "I find it relieving to know that whether you believe in a soul or not, or have a religion or not, or an assumption about how the universe works, that ...
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Medicine 2014-05-27

HIV can cut and paste in the human genome

For the first time researchers have succeeded in altering HIV virus particles so that they can simultaneously, as it were, 'cut and paste' in our genome via biological processes. Developed at the Department of Biomedicine at Aarhus University, the technology makes it possible to repair genomes in a new way. It also offers good perspectives for individual treatment of both hereditary diseases and certain viral infections: "Now we can simultaneously cut out the part of the genome that is broken in sick cells, and patch the gap that arises in the genetic information which ...
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'Virtual human' shows that stiff arteries can explain the cause of high blood pressure
Medicine 2014-05-27

'Virtual human' shows that stiff arteries can explain the cause of high blood pressure

High blood pressure is highly age-related and affects more than 1 billion people worldwide. But doctors can't fully explain the cause of 90 per cent of all cases. A computer model of a "virtual human" suggests that stiff arteries alone are enough to cause high blood pressure. "Our results suggest that arterial stiffness represents a major therapeutic target. This is contrary to existing models, which typically explain high blood pressure in terms of defective kidney function," says Klas Pettersen, a researcher at the Norwegian University of Life Sciences and first author ...
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Why does bacon smell so good? (video)
Science 2014-05-27

Why does bacon smell so good? (video)

WASHINGTON, May 27, 2014 — We all know bacon is delicious, but what is it about cooking bacon that makes it smell so tantalizing? In the American Chemical Society's (ACS') latest Reactions video, the team puts its nose into everyone's favorite breakfast food. We collaborated with the Compound Interest blog to break down the science of that sweet smell. The video is available at http://youtu.be/2P_0HGRWgXw Subscribe to the series at Reactions YouTube, and follow us on Twitter @ACSreactions to be the first to see our latest videos. INFORMATION: The American Chemical ...
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Scientists map the worst times of day for people allergic to grass pollen
Science 2014-05-27

Scientists map the worst times of day for people allergic to grass pollen

Atishoo! Help, there are flowering grasses around, please stay indoors – while your friends enjoy the nice summer weather! Traditionally, people allergic to grass pollen are advised to be aware of high pollen concentrations during the day, and to reduce their outdoor activities during this period. A new study led by researchers from Aarhus University shows that it is considerably more complicated to avoid grass pollen. Based on a three-year study with intensive measurements at three different locations in Aarhus, they divide the grass pollen season into three periods, ...
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Medicine 2014-05-27

Sperm cells are extremely efficient at swimming against a current

Like salmon traveling upstream to spawn, sperm cells are extremely efficient at swimming against the current, according to research to be published this week. The discovery, to be published in the journal eLife by researchers at MIT and Cambridge University, may help us to understand how some sperm travel such long distances, through difficult terrain, to reach and fertilize an egg. Of the hundreds of millions of sperm cells that begin the journey up the oviducts, only a few hardy travelers will ever reach their destination. Not only do the cells have to swim in the ...
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Attack is not always the best defense
Science 2014-05-27

Attack is not always the best defense

Jena (Germany) It is something like the police force of our body: the immune system. It disables intruding pathogens, it dismantles injured tissue and boosts wound healing. In this form of 'self-defense' inflammatory reactions play a decisive role. But sometimes the body's defense mechanism gets out of control and cells or tissues are affected: "Then excessive reactions can occur and illnesses along with them," Prof. Dr. Oliver Werz of the Friedrich Schiller University Jena says. He gives asthma, rheumatism, arteriosclerosis and cancer as examples: "For many of these diseases ...
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The secret cargo of mosquitoes
Science 2014-05-27

The secret cargo of mosquitoes

The parasite Dirofilaria repens is a roundworm that primarily attacks the subcutaneous tissue of dogs and causes lumps in the skin, swelling, and itching. Dogs, cats, foxes, wolves and martens can be infected in addition to dogs. "In humans, 16 cases of human dirofilariosis have been recorded since the year 2000, but the dark figure is definitely higher", says the lead author Katja Silbermayr. Humans, however, are so-called dead end hosts; the parasite does not reproduce in humans and therefore poses no major risk. Silbermayr is a veterinarian and performs research on ...
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Seeing e-cigarette use encourages young adult tobacco users to light up
Science 2014-05-27

Seeing e-cigarette use encourages young adult tobacco users to light up

VIDEO: "Whether participants were exposed to someone smoking a combustible or an e-cigarette, the urge to smoke a combustible cigarette was just as high in either condition, " King said. "If the... Click here for more information. Seeing people use electronic cigarettes (e-cigarettes) increases the urge to smoke among regular combustible cigarettes users, according to a new study of young adult smokers. This elevated desire is as strong as when observing someone ...
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