Dartmouth study provides first global evidence that foreign aid boosts public opinion
2014-02-11
A study by Dartmouth and Australian researchers provides the first empirical evidence using data from a variety of countries that foreign aid can greatly improve foreign public opinion of donor countries.
The findings are based on a U.S. foreign aid program targeting HIV and AIDS -- the President's Emergency Plan for AIDS Relief (PEPFAR) -- that has substantially improved public perception of the United States in the more than 80 developing countries receiving the aid. But the findings have broader policy implications for an emerging international order in which major ...
Game changer: Biomarker identified for noncancerous pancreatic cysts
2014-02-11
INDIANAPOLIS -- Researchers at the Indiana University School of Medicine have discovered a highly accurate, noninvasive test to identify benign pancreatic cysts, which could spare patients years of nerve-racking trips to the doctor or potentially dangerous surgery.
The findings are reported in "Vascular Endothelial Growth Factor, a Novel and Highly Accurate Pancreatic Fluid Biomarker for Serous Pancreatic Cysts" online in the Journal of the American College of Surgeons.
The test, which analyzes fluid from pancreatic cysts, can identify a common type of benign cyst that ...
New target isolated for leukemia drug development
2014-02-11
SAN ANTONIO (February 11, 2014) – There are potentially effective treatments for acute myeloid leukemia (AML), but they only work in 20 to 40 percent of cases. In a paper published today in Leukemia, a Nature journal, a UT Health Science Center researcher has pinpointed a protein that could play a key, previously unknown role in the development of pediatric AML — promising new information in the quest to treat and cure childhood leukemias.
AML starts at the point when cells mature into different kinds of blood cells. In AML, the cancerous cells grow and proliferate in ...
No clowning around: Juggling sheds light on how we run
2014-02-11
Juggling may seem like mere entertainment, but a study led by Johns Hopkins engineers used this circus skill to gather critical clues about how vision and the sense of touch help control the way humans and animals move their limbs in a repetitive way, such as in running. The findings eventually may aid in the treatment of people with neurological diseases and could lead to prosthetic limbs and robots that move more efficiently.
The study was published online recently by the Journal of Neurophysiology and will be the cover article in the journal's March 2014 print edition.
In ...
EU rules are denying children latest cancer drugs
2014-02-11
Children with cancer are being denied new, potentially life-saving drugs, because EU rules are allowing companies to trial some drugs only in adults, leading cancer experts warn today.
Changes to how EU rules are implemented could allow children access to a goldmine of potential cancer drugs which have currently only been tested in adults – by making it more difficult for pharma companies to avoid testing them in under-18s too.
Under the current system, pharma companies often gain exemptions from carrying out expensive testing of cancer drugs in patients under the age ...
Heart attack research discovers new treatment target
2014-02-11
New Orleans, LA – Research led by David Lefer, PhD, Professor and Director of the Cardiovascular Center of Excellence at LSU Health Sciences Center New Orleans School of Medicine, demonstrates for the first time cross-talk between two protective signaling molecules during a heart attack. By providing new and important information about the mechanisms involved in heart attacks and organ transplantation, the research identifies a potential new treatment target for heart disease. The paper will be published in Proceedings of the National Academy of Sciences (PNAS) Online Early ...
Point-of-care ultrasound for suspected appendicitis in kids proves accurate
2014-02-11
New York, NY – Using portable ultrasound as a first-line imaging study in kids with suspected appendicitis helps reduce emergency room length of stay and reduces the need for CT scans, according to a team of Mount Sinai researchers. Bedside ultrasound, often referred to as point-of-care ultrasonography, has a specificity of about 94%, meaning that it misses few cases, , the Mt. Sinai researchers add. Results from the study are published online February 10 in the peer-reviewed journal Academic Emergency Medicine.
"From an institutional perspective, this is the most common ...
ASTRO and SSO issue consensus guideline on margins for breast-conserving surgery with WBI
2014-02-11
Fairfax, Va., February 10, 2014 – The American Society for Radiation Oncology (ASTRO) and the Society of Surgical Oncology (SSO) are pleased to announce the publication of the consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer. The guideline document represents an intensive collaboration among experts in the radiation oncology and surgical oncology fields, led by Meena S. Moran, MD, associate professor of the Department of Therapeutic Radiology at Yale School of Medicine in New Haven, Conn., ...
Maps show expected redistribution of global species due to climate change
2014-02-11
As climate change unfolds over the next century, plants and animals will need to adapt or shift locations to follow their ideal climate. A new study provides an innovative global map of where species are likely to succeed or fail in keeping up with a changing climate. The findings appear in the science journal Nature.
As part of a UC Santa Barbara National Center for Ecological Analysis and Synthesis (NCEAS) working group, 18 international researchers analyzed 50 years of sea surface and land temperature data (1960-2009). They also projected temperature changes under ...
Obese children more likely to have complex elbow fractures and further complications
2014-02-11
ROSEMONT, Ill.─Pediatric obesity is currently an epidemic, with the prevalence having quadruped over the last 25 years. Children diagnosed with obesity can be at risk for various long-term health issues and may be putting their musculoskeletal system at risk. According to new research in the February issue of the Journal of Bone and Joint Surgery (JBJS), obese children who sustain a supracondylar humeral (above the elbow) fracture can be expected to have more complex fractures and experience more postoperative complications than children of a normal weight.
"These ...
Giant mass extinction may have been quicker than previously thought
2014-02-11
The largest mass extinction in the history of animal life occurred some 252 million years ago, wiping out more than 96 percent of marine species and 70 percent of life on land — including the largest insects known to have inhabited the Earth. Multiple theories have aimed to explain the cause of what's now known as the end-Permian extinction, including an asteroid impact, massive volcanic eruptions, or a cataclysmic cascade of environmental events. But pinpointing the cause of the extinction requires better measurements of how long the extinction period lasted.
Now researchers ...
High pollutant levels in Guánica Bay 'represent serious toxic threat' to corals
2014-02-11
The pollutants measured in the sediments of Guánica Bay, Puerto Rico, in a new NOAA study were among the highest concentrations of PCBs, chlordane, chromium and nickel ever measured in the history of NOAA's National Status & Trends, a nationwide contaminant monitoring program that began in 1986.
Researchers from the National Ocean Service's National Centers for Coastal Ocean Science (NCCOS) studied the reef's ecology to help establish baseline conditions that coastal managers can use to measure changes resulting from new efforts to manage pollution. Among the items studied ...
Design prototype chip makes possible a fully implantable cochlear implant
2014-02-11
BOSTON (Feb. 10, 2014) — Researchers from Massachusetts Eye and Ear, Harvard Medical School, and Massachusetts Institute of Technology (MIT) have designed a prototype system-on-chip (SoC) that could make possible a fully implanted cochlear implant. They will present their findings on Feb. 11at the IEEE International Solid State Circuits Conference in San Francisco.
A cochlear implant is a device that electronically stimulates the auditory nerve to restore hearing in people with profound hearing loss. Conventional cochlear implants are made up of an external unit with ...
NASA's TRMM satellite eyes rainfall in Tropical Cyclone Fobane
2014-02-11
Some towering thunderstorms were spotted in Tropical Cyclone Fobane as NASA's TRMM satellite passed over the Southern Indian Ocean on February 10. Fobane was formerly Tropical Cyclone 14S and when it strengthened into a tropical storm it was renamed.
NASA and the Japan Aerospace Exploration Agency manages the Tropical Rainfall Measuring Mission satellite known as TRMM. TRMM has the capability to measure rainfall rates from space and data that can be used to determine the heights of thunderstorms that make up a storm. When TRMM passed over Tropical Cyclone Fobane on February ...
Cars, computers, TVs spark obesity in developing countries
2014-02-11
The spread of obesity and type-2 diabetes could become epidemic in low-income countries, as more individuals are able to own higher priced items such as TVs, computers and cars. The findings of an international study, led by Simon Fraser University health sciences professor Scott Lear, are published today in the Canadian Medical Association Journal.
Lear headed an international research team that analyzed data on more than 150,000 adults from 17 countries, ranging from high and middle income to low-income nations.
Researchers, who questioned participants about ownership ...
Recycling of 'chauffeur protein' helps regulate fat production
2014-02-11
Studying a cycle of protein interactions needed to make fat, Johns Hopkins researchers say they have discovered a biological switch that regulates a protein that causes fatty liver disease in mice. Their findings, they report, may help develop drugs to decrease excessive fat production and its associated conditions in people, including fatty liver disease and diabetes.
A summary of the research appeared online on Jan. 29 in the Journal of Biological Chemistry.
"We've learned how the body finely tunes levels of a protein called SCAP that is required to turn on fat production ...
Long distance signals protect brain from viral infections
2014-02-11
The brain contains a defense system that prevents at least two unrelated viruses—and possibly many more—from invading the brain at large. The research is published online ahead of print in the Journal of Virology.
"Our work points to the remarkable ability of the immune system, even within the brain, to protect us against opportunistic viruses," says Anthony van den Pol of Yale University, an author on the study.
The research explains a long-standing mystery. The olfactory mucosa in the nose can serve as a conduit for a number of viruses to enter the brain including ...
Mayo Clinic identifies a key cellular pathway in prostate cancer
2014-02-11
ROCHESTER, Minn. — Mayo Clinic researchers have shed light on a new mechanism by which prostate cancer develops in men. Central to development of nearly all prostate cancer cases are malfunctions in the androgen receptor — the cellular component that binds to male hormones. The research team has shown that SPOP, a protein that is most frequently mutated in human prostate cancers, is a key regulator of androgen receptor activity that prevents uncontrolled growth of cells in the prostate and thus helps prevent cancer. The findings appear in the journal Cell Reports.
"By ...
Flowing water on Mars appears likely but hard to prove
2014-02-11
Martian experts have known since 2011 that mysterious, possibly water-related streaks appear and disappear on the planet's surface. Georgia Institute of Technology Ph.D. candidate Lujendra Ojha discovered them while an undergraduate at the University of Arizona. These features were given the descriptive name of recurring slope lineae (RSL) because of their shape, annual reappearance and occurrence generally on steep slopes such as crater walls. Ojha has been taking a closer look at this phenomenon, searching for minerals that RSL might leave in their wake, to try to understand ...
With their amazing necks, ants don't need 'high hopes' to do heavy lifting
2014-02-11
COLUMBUS, Ohio—High hopes may help move a rubber tree plant (as the old song goes), but the real secret to the ant's legendary strength may lie in its tiny neck joint.
In the Journal of Biomechanics, researchers report that the neck joint of a common American field ant can withstand pressures up to 5,000 times the ant's weight.
"Ants are impressive mechanical systems—astounding, really," said Carlos Castro, assistant professor of mechanical and aerospace engineering at The Ohio State University. "Before we started, we made a somewhat conservative estimate that they ...
Chips that listen to bacteria
2014-02-11
VIDEO:
The development of colony biofilms by Pseudomonas aeruginosa is affected by redox-active compounds called phenazines. A phenazine-null mutant forms a hyperwrinkled colony with prominent spokes, while wild-type colonies are more...
Click here for more information.
New York, NY—February 10, 2014—In a study published today in Nature Communications, a research team led by Ken Shepard, professor of electrical engineering and biomedical engineering at Columbia Engineering, ...
Manga comics may help promote fruit consumption among youth
2014-02-11
AUDIO:
May May Leung, Ph.D., R.D., discusses how a recent pilot study in Brooklyn, N.Y., with minority students found that exposure to manga comics (Japanese comic art) promoting fruit intake significantly...
Click here for more information.
PHILADELPHIA, PA, February 10, 2014 – A recent pilot study in Brooklyn, New York, with minority students found that exposure to Manga comics (Japanese comic art) promoting fruit intake significantly improved healthy snack selection. As ...
Political values influence people's response to health disparities messages
2014-02-11
PHILADELPHIA (February 10, 2014) – Policymakers and advocates discussing health disparities in the United States would be wise to consider the political affiliation of their audience, suggests a new study published in the Journal of Health Communication: International Perspectives (2014).
"Understanding Public Resistance to Messages about Health Disparities" was written by Sarah E. Gollust, University of Minnesota School of Public Health; and Joseph N. Cappella, Annenberg School for Communication, University of Pennsylvania. The study examines how political ...
TGen study uncovers possible genetic markers in breast cancer that spreads to the brain
2014-02-11
PHOENIX, Ariz. — Feb. 10, 2014 — The Translational Genomics Research Institute (TGen) has uncovered possible genetic origins of breast cancer that spreads to the brain, according to a first-of-its-kind study published in the scientific journal PLOS ONE.
The compendium of genetic targets uncovered by TGen now can be used to identify potential new methods of diagnosis and new drug therapies for the estimated 45,000 patients in the U.S. each year whose cancer spreads from the breast to the brain.
The 3-year study is significant since these patients currently have few treatments ...
New advance in 3-D printing and tissue engineering technology
2014-02-11
Boston, MA – Researchers at Brigham and Women's Hospital (BWH) and Carnegie Mellon University have introduced a unique micro-robotic technique to assemble the components of complex materials, the foundation of tissue engineering and 3D printing.
Described in the Jan. 28, 2014, issue of Nature Communications, the research was conducted by Savas Tasoglu, PhD, MS, research fellow in the BWH Division of Renal Medicine, and Utkan Demirci, PhD, MS, associate professor of Medicine in the Division of Biomedical Engineering, part of the BWH Department of Medicine, in collaboration ...
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