Boston, MA -- According to a large, long-term study from Harvard School of Public Health (HSPH), 40% of all colorectal cancers might be prevented if people underwent regular colonoscopy screening. The new research also supports existing guidelines that recommend that people with an average risk of colorectal cancer should have a colonoscopy every 10 years. The new study helps address previous uncertainty about the effectiveness of colonoscopy in reducing colorectal cancer incidence and mortality -- particularly among people with cancer that originates in the proximal, ...

Two thirds of these occur in low and middle income countries, the figures suggest. The authors base their findings on 4000 articles written in English and published from 1976 onwards, which looked at substandard medical care given to hospital patients around the globe. The researchers focused on seven key markers for substandard care: harm from prescribed medications; urinary tract infections associated with catheters; bloodstream infections associated with catheters; pneumonia acquired in hospital; blood clots (VTEs);falls; and bed sores. They used an approach similar ...

It is common for parents to influence mate choice — from arranged marriages to more subtle forms of persuasion — but they often disagree with their children about what makes a suitable partner. A new study has found an evolutionary explanation for why some parents try to control who their children pair up with. The study, involving a University of Bristol researcher and published today in the journal Evolution & Human Behavior, shows that this conflict over mate choice may be rooted in an evolutionary conflict over resources. Dr Tim Fawcett, a research fellow in Bristol's ...

Habitable conditions on Earth will be possible for at least another 1.75 billion years – according to astrobiologists at the University of East Anglia. Findings published today in the journal Astrobiology reveal the habitable lifetime of planet Earth – based on our distance from the sun and temperatures at which it is possible for the planet to have liquid water. The research team looked to the stars for inspiration. Using recently discovered planets outside our solar system (exoplanets) as examples, they investigated the potential for these planets to host life. The ...

Boston, MA – More than 43 million people are injured worldwide each year due to unsafe medical care, according to a new study from Harvard School of Public Health (HSPH). These injuries result in the loss of nearly 23 million years of "healthy" life. The findings represent a major new effort to calculate the global burden of unsafe medical care across a range of adverse health events. The study appears online September 18, 2013 in BMJ Quality & Safety. "This is the first attempt to quantify the human suffering that results from unsafe care," said lead author Ashish ...

Researchers from the University of Montreal and their colleagues have found brain activity beyond a flat line EEG, which they have called Nu-complexes (from the Greek letter Νν). According to existing scientific data, researchers and doctors had established that beyond the so-called "flat line" (flat electroencephalogram or EEG), there is nothing at all, no brain activity, no possibility of life. This major discovery suggests that there is a whole new frontier in animal and human brain functioning. The researchers observed a human patient in an extreme deep hypoxic ...

Cardiologists are increasingly accessing coronary arteries by way of the wrist rather than the groin to insert life-saving stents into patients with blocked arteries, according to the first broad report of the American College of Cardiology's clinical data registries published online today in the Journal of the American College of Cardiology. The report, "Cardiovascular Care Facts: A Report from the National Cardiovascular Data Registry - 2011," includes data about stents from the CathPCI Registry, the ACC's national database of hospital records on stenting and angioplasty, ...

A duo of scientists at Penn State University has achieved a major milestone in understanding how genomic "dark matter" originates. This "dark matter" -- called non-coding RNA -- does not contain the blueprint for making proteins and yet it comprises more than 95 percent of the human genome. The researchers have discovered that essentially all coding and non-coding RNA originates at the same types of locations along the human genome. The team's findings eventually may help to pinpoint exactly where complex-disease traits reside, since the genetic origins of many diseases ...

A temperature sensor developed by researchers at the University of Cambridge could improve the efficiency, control and safety of high-temperature engines. The sensor minimises drift –degradation of the sensor which results in faulty temperature readings and reduces the longevity of engine components. The new sensor, or thermocouple, has been shown to reduce drift by 80 per cent at temperatures of 1200 degrees Celsius, and by 90 per cent at 1300 degrees Celsius, potentially doubling the lifespan of engine components. The results are published in the September issue of ...

A team of researchers led by King's College London has for the first time identified a new gene which may have the ability to prevent HIV, the virus that causes AIDS, from spreading after it enters the body. Published in Nature today, the study is the first to identify a role for the human MX2 gene in inhibiting HIV. Researchers say this gene could be a new target for effective, less toxic treatments where the body's own natural defence system is mobilised against the virus. The work was funded by the Medical Research Council and the National Institute for Health ...

Bethesda, MD (Sept. 18, 2013) — A study published in the Sept. 19 New England Journal of Medicine provides some of the clearest evidence to date that colonoscopy has advantages over sigmoidoscopy for the prevention of colorectal cancer. Researchers followed 88,902 study participants for 22 years and found that 1,815 developed colorectal cancer. Investigators estimated that 40 percent of those cancers could have been prevented if all of the patients in the study had received colonoscopy. "Thanks to colonoscopy, fewer people than ever before are developing or dying from ...

Toronto, Canada (September 18, 2013) – In a world-first, decompression surgery has been shown to be an effective procedure to treat cervical spondylotic myelopathy (CSM) – a common progressive, degenerative disease of the spine that can lead to paralysis – according to the results of a multi-centre clinical trial published today. The study, with its use of multiple outcome measures to determine patient improvement, is the first research of its kind to show that decompression surgery has a significant improvement in both the symptoms and quality of life of CSM patients ...

MILWAUKEE – The loss of estrogens at menopause increases a woman's risk of dementia and Alzheimer's disease, yet hormone replacement therapy can cause harmful side effects. Knowing the exact mechanism of estrogen activation in the brain could lead to new targets for drug development that would provide middle-aged women the cognitive benefits of hormone replacement therapy without increasing their risk for cardiovascular disease or breast cancer. In a new study, Karyn Frick, professor of psychology at the University of Wisconsin-Milwaukee (UWM), uncovers details about ...

Bug spray, citronella candles, mosquito netting – most people will do anything they can to stay away from insects during the warmer months. But those creepy crawlers we try so hard to avoid may offer substantial solutions to some of life's problems. Researchers using the cutting-edge X-ray technology at the U.S. Department of Energy's Advanced Photon Source (APS) were able to take an inside look at several insects, gathering results that go beyond learning about insect physiology and biology. What they found could provide a blueprint for a material used for artificial ...

Physicists at JILA have created a crystal-like arrangement of ultracold gas molecules that can swap quantum "spin" properties with nearby and distant partners. The novel structure might be used to simulate or even invent new materials that derive exotic properties from quantum spin behavior, for electronics or other practical applications. Described in a Nature paper* posted online on Sept. 18, 2013, the JILA experiment is the first to record ultracold gas molecules exchanging spins at a distance, a behavior that may be similar to that of intriguing solids such as "frustrated" ...

CAMBRIDGE, MA -- If you got beat up by a bully on your walk home from school every day, you would probably become very afraid of the spot where you usually met him. However, if the bully moved out of town, you would gradually cease to fear that area. Neuroscientists call this phenomenon "memory extinction": Conditioned responses fade away as older memories are replaced with new experiences. A new study from MIT reveals a gene that is critical to the process of memory extinction. Enhancing the activity of this gene, known as Tet1, might benefit people with posttraumatic ...

COLUMBIA, Mo. – Individuals often turn to others for advice when making choices. Perhaps, it seems fitting then, that individuals would seek out others when they are faced with important health decisions. Yet, health communicators have debated whether stories should be included in patient decision-aids (which are informational materials designed to help patients make educated choices about their health) because they worry stories are too biased. Now, an MU researcher has found that stories used in decision-aids don't necessarily bias patients' decision-making; rather, certain ...

ROCHESTER, Minn. -- A genetic mutation, known as GBA, that leads to early onset of Parkinson's disease and severe cognitive impairment (in about 4 to 7 percent of all patients with the disease) also alters how specific lipids, ceramides and glucosylceramides are metabolized. Mayo Clinic researchers have found that Parkinson's patients who do not carry the genetic mutation also have higher levels of these lipids in the blood. Further, those who had Parkinson's and high blood levels were also more likely to have cognitive impairment and dementia. The research was recently ...

MIAMI, FLORIDA, (September 18, 2013)—You might find it hard to believe that dust clouds from the African Sahara can travel thousands of miles across the Atlantic Ocean, but it does every year and in large quantities. In a recent study, Joseph Prospero, professor emeritus at the University of Miami Rosenstiel School of Marine and Atmospheric Science and collaborators at the University of Houston and Arizona State University found that the average air concentrations of inhalable particles more than doubled during a major Saharan dust intrusion in Houston, Texas. ...

Using technology he helped develop, Vanderbilt University scientist Bryan Venters, Ph.D., has shed new light on the "dark matter" of the genome and has begun to explore a possible new approach to treating cancer. "Clarity is everything," said Venters, assistant professor of Molecular Physiology and Biophysics who further developed the high-resolution technology as a postdoctoral fellow in the lab of Frank Pugh, Ph.D., at Pennsylvania State University before moving to Vanderbilt in January. Venters and Pugh are co-authors of a paper published this week in the journal ...

The extra demands on parents of chronically ill children cause stress that affects the whole family, according to a systematic review conducted by Case Western Reserve University researchers that also explored what factors in the child's care most contribute to the added strain. The findings, reported in the August issue of the Journal of Pediatric Psychology article, "Parenting Stress Among Caregivers of Children With Chronic Illness: A Systematic Review," were based on an assessment of 96 peer-reviewed studies in 12 countries between 1980 and 2012. Researchers examined ...

Sequencing the DNA of an organism, whether human, plant, or jellyfish, has become a straightforward task, but assembling the information gathered into something coherent remains a massive data challenge. Researchers using computational resources at the San Diego Supercomputer Center (SDSC) at the University of California, San Diego, have created a faster and more effective way to assemble genomic information, while increasing In a paper presented the past month at the 39th International Conference on Very Large Databases (VLDB2013) in Riva del Garda, Italy, Xifeng Yan, ...

PROVIDENCE, R.I. [Brown University] — To stay ahead in the race against drug-resistant infections, scientists constantly search for and exploit vulnerabilities in deadly bacteria. Now, researchers from Brown and the Massachusetts Institute of Technology have used a novel compound to exploit an Achilles' heel in the bacterium that causes tuberculosis. In a series of laboratory experiments, the researchers have shown that it is possible to kill Mycobacterium tuberculosis by inhibiting ClpP, a cellular enzyme that is not targeted by any antibacterial drug on the market. ...

CLEMSON, S.C. — Cattle are what they eat. The forage — grasses and other plants ­— beef cattle eat affects the nutrition and tastiness of the meat. Clemson University animal science researchers report that steers grazing on one of five forages kept in paddocks showed significant differences in growth, carcass and meat quality. The research can help cattle producers with alternatives to corn and feed when they are looking to add weight and value to their animals prior to sale. A team of researchers supported by the Clemson University Experiment Station, Extension Service ...

Wednesday, September 18, 2013 [Granada, Spain] – New research findings on avocado consumption, presented as two posters at the IUNS 20th International Congress of Nutrition, in Granada, Spain suggest that although calorie consumption at dinner was unchanged, inclusion or addition of fresh Hass Avocado to a meal may help to reduce hunger and the desire to eat in overweight adults. Results also showed that including or adding avocado to a meal resulted in smaller post-meal rises in insulin compared to eating a meal without avocado. Findings were based on a Hass Avocado ...