AUGUSTA, Ga. – A common nutritional supplement may be part of the magic in improving the survival rates of babies born with heart defects, researchers report. Carnitine, a compound that helps transport fat inside the cell powerhouse where it can be used for energy production, is currently used for purposes ranging from weight loss to chest pain. New research shows it appears to normalize the blood vessel dysfunction that can accompany congenital heart defects and linger even after corrective surgery, said Dr. Stephen M. Black, cell and molecular physiologist at the ...

This news release is available in French. AUDIO: Dr. Beth Foster, pediatric nephrologist at the Montreal Children's Hospital in Montreal explains the importance of her findings. Click here for more information. Montreal, May 8, 2013 – Children on dialysis for severe kidney disease have a dramatically reduced risk of death compared to 20 years ago, a new study shows. The findings, from a study ...

Children with autism see simple movement twice as quickly as other children their age, and this hypersensitivity to motion may provide clues to a fundamental cause of the developmental disorder, according to a new study. Such heightened sensory perception in autism may help explain why some people with the disorder are painfully sensitive to noise and bright lights. It also may be linked to some of the complex social and behavioral deficits associated with autism, says Duje Tadin, one of the lead authors on the study and an assistant professor of brain and cognitive ...

WASHINGTON — Using MRI, neuroscientists at Georgetown University Medical Center found significant differences in brain anatomy when comparing men and women with dyslexia to their non-dyslexic control groups, suggesting that the disorder may have a different brain-based manifestation based on sex. Their study, investigating dyslexia in both males and females, is the first to directly compare brain anatomy of females with and without dyslexia (in children and adults). Their findings were published online in the journal Brain Structure and Function. Because dyslexia is ...

A new article available online in the American Journal of Public Health by two Johns Hopkins Bloomberg School of Public Health faculty makes a compelling case that end-of-life care issues need to become an integral part of the public health agenda. Dan Morhaim, MD, and Keshia Pollack, PhD, point out that the low rate of completion of advance directives in the minority population can be identified as another health care disparity. Advance directive documents are free, legally binding and readily available, yet too few Americans have completed one. Although end-of-life ...

URBANA – Tomatoes and soy foods may be more effective in preventing prostate cancer when they are eaten together than when either is eaten alone, said a University of Illinois study. "In our study, we used mice that were genetically engineered to develop an aggressive form of prostate cancer. Even so, half the animals that had consumed tomato and soy had no cancerous lesions in the prostate at study's end. All the mice in the control group--no soy, no tomato--developed the disease," said John Erdman, a U of I professor of food science and nutrition. From the time they ...

A carnivorous, cannibalistic tadpole may play a role in understanding the evolution and development of digestive organs, according to research from North Carolina State University. These findings may also shed light on universal rules of organ development that could lead to better diagnosis and prevention of intestinal birth defects. NC State developmental biologist Nanette Nascone-Yoder, graduate student Stephanie Bloom and postdoc Cris Ledon-Rettig looked at Xenopus laevis (African clawed frog) and Lepidobatrachus laevis (Budgett's frog) tadpoles. These frog species ...

SAN DIEGO – Robot-assisted surgery to remove kidney cancers has seen a rapid increase in use, and has both replaced and proven safer than laparoscopic procedures for the same purpose, according to a study by the Vattikuti Urology Institute at Henry Ford Hospital in Detroit. However, the study also shows that robotic partial nephrectomy (RPN) – while resulting in fewer complications than both open (OPN) and laparoscopic (LPN) removal of cancerous kidney tissue – also involves more "excessive" hospital charges. "Excessive hospital charges were significantly higher with ...

From Ireland to the Balkans, Europeans are basically one big family, closely related to one another for the past thousand years, according to a new study of the DNA of people from across the continent. The study, co-authored by Graham Coop, a professor of evolution and ecology at the University of California, Davis, will be published May 7 in the journal PLoS Biology. "What's remarkable about this is how closely everyone is related to each other. On a genealogical level, everyone in Europe traces back to nearly the same set of ancestors only a thousand years ago," Coop ...

Minneapolis, MN, May 7, 2013 - Inherited ventricular arrhythmias are an important cause of morbidity and sudden cardiac death in children who have structurally normal hearts. Despite conventional medical therapy, some of these children remain symptomatic with recurrent life-threatening arrhythmias, syncope, or frequent discharges from implantable cardioverter defibrillators (ICDs). Video-assisted thoracoscopic left cardiac sympathetic denervation (VATS-LCSD) is a minimally invasive procedure that can help many of these children with refractory cardiac arrhythmias. The results ...

From Ireland to the Balkans, Europeans are all closely related according to a new study of the DNA of people from across the continent. The study, conducted by Graham Coop at the University of California, Davis, and Peter Ralph of the University of Southern California, examined relatedness among Europeans up to about 3,000 years ago, comparing genetic sequences from over 2,000 individuals. Their results are published 7 May in the open access journal PLOS Biology. The researchers found that the extent to which two people are related tends to be smaller the farther apart ...

Many adults 45 years and older in Africa have limited functional ability The number of adults living into older age in sub-Saharan Africa is rapidly growing yet many older men and women will have an illness or disability that limits their ability to function, according to a study by researchers from the US and Malawi published in this week's PLOS Medicine. The researchers, led by Collin Payne from the University of Pennsylvania, also show that remaining life spent with severe limitations at age 45 in a sub Saharan African setting (Malawi) is comparable to that of 80-year-olds ...

Not only are women who have experienced violence from their partner (intimate partner violence) at higher risk of becoming depressed, but women who are depressed may also be at increased risk of experiencing intimate partner violence, according to a study by international researchers published in this week's PLOS Medicine. Furthermore, there may also be a link between intimate partner violence and subsequent suicide among women, but little evidence to support a similar finding in men. The researchers led by Karen Devries from the London School of Hygiene & Tropical ...

Heiman Wertheim and Arjun Chandna from Oxford University and colleagues describe the launch and impact of VINARES, an initiative to strengthen antimicrobial stewardship in Viet Nam, which may be instructive for other countries struggling to address the threat of antimicrobial resistance. Antimicrobial resistance is increasingly recognised as a serious contemporary global health threat (with numerous calls for action from the international community), but while interventions to control antimicrobial resistance are available, implementation is developing countries (where ...

New PLOS Collection assesses the measurement of whether much needed health interventions are reaching women and children across the developing world Measuring coverage of maternal, newborn and child health in low- and middle-income countries is critical to ensuring that health interventions are reaching the women and children who need them most, says a new Collection of articles published by PLOS this week. Accurate measurement of the effectiveness of those interventions for combatting diseases such as pneumonia and malaria, and preventing the transmission of HIV from ...

Programming an implantable cardioverter-defibrillator (ICD) with a long-detection interval compared with a standard-detection interval resulted in a reduction in anti-tachycardia pacing episodes, ICD shocks delivered, and inappropriate shocks, according to a study in the May 8 issue of JAMA. "Therapy with ICDs is now the standard of care in primary and secondary prevention. As indications for implants have expanded, concern about possible adverse effects of ICD therapies on prognosis and quality of life has arisen. Several authors have reported that ICD therapies, both ...

Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and stomach ulcers and is linked to stomach cancer, findings that may help explain some of the observed variation in individual risk for H pylori infection, according to a study in the May 8 issue of JAMA. "[H pylori] is the major cause of gastritis (80 percent) and gastroduodenal ulcer disease (15 percent-20 percent) and the only bacterial pathogen believed ...

"Traumatic brain injury (TBI) is a major cause of hospitalization, disability, and death-worldwide, and among older adults, falling is the most common cause of TBI," writes Niina Korhonen, B.M., of the Injury and Osteoporosis Research Center, Tampere, Finland, and colleagues in a Research Letter. The authors previously reported that the number and incidence of adults 80 years of age or older admitted to the hospital due to fall-induced TBI in Finland increased from 1970 through 1999. This analysis is a follow-up of this population through 2011. The study included data ...

PROVIDENCE, R.I. [Brown University] — Vertebrates are predisposed to act to gain rewards, and to lay low to avoid punishment. Try to teach chickens to back away from food in order to obtain it, and you'll fail, as researchers did in 1986. But (some) humans are better thinkers than chickens. In the May 8 edition of the Journal of Neuroscience, researchers show that the level of theta brainwave activity in the prefrontal cortex predicts whether people will be able to overcome these ingrained biases when doing so is required to achieve a goal. The study helps explain a distinctly ...

Cold Spring Harbor, N.Y. – When animals are on the hunt for food they likely use many senses, and scientists have wondered how the different senses work together. New research from the laboratory of CSHL neuroscientist and Assistant Professor Adam Kepecs shows that when rats actively use the senses of smell (sniffing) and touch (through their whiskers) those two processes are locked in synchronicity. The team's paper, published today in the Journal of Neuroscience, shows that sniffing and "whisking" movements are synchronized even when they are running at different frequencies. Studies ...

Cleveland: Only 42 percent of the deaths occurring within 30 days of percutaneous coronary interventions (PCI) were attributable to complications from the procedure, according to a Cleveland Clinic study published online in the Journal of the American College of Cardiology. The research suggests alternative outcome reporting mechanisms for 30-day mortality for PCI should be considered before mandatory reporting regulations are put into place. PCI is a non-surgical procedure in which balloons and/or stents are used to open blocked or narrowed arteries, which are typically ...

Exposing skin to sunlight may help to reduce blood pressure, cut the risk of heart attack and stroke – and even prolong life, a study suggests. Researchers have shown that when our skin is exposed to the sun's rays, a compound is released in our blood vessels that helps lower blood pressure. The findings suggest that exposure to sunlight improves health overall, because the benefits of reducing blood pressure far outweigh the risk of developing skin cancer. The study has been carried out by the University of Edinburgh. Heart disease and stroke linked to high ...

Women with unintended pregnancy are four times more likely to suffer from postpartum depression at twelve months postpartum, suggests a new study published today (8 May) in BJOG: An International Journal of Obstetrics and Gynaecology. The study, conducted at the University of North Carolina prenatal clinics questioned participants about pregnancy intention at 15-19 weeks gestational age, and women were classified as having an intended, mistimed or unwanted pregnancy. There were 433 women (64%) with an intended pregnancy, 207 (30%) with a mistimed pregnancy and 40 (6%) ...

An analysis by researchers at the Institute for Immigration Research (IIR) at George Mason University shows that the Boston Marathon bombings had little effect on conversations on social media regarding immigration reform. Using two different data mining applications, the researchers collected more than 750,000 tweets containing the word "immigration" beginning in February 2013. "The Boston Marathon bombings on April 15, 2013 provided an unexpected opportunity to examine how this event has affected the immigration reform debate," says Jim Witte, director of the IIR. ...

In 2015, NASA, for the first time, will fly a space mission utilizing a radically different propellant—one which has reduced toxicity and is environmentally benign. This energetic ionic liquid, or EIL, is quite different from the historically employed hydrazine-based propellant, which was first used as a rocket fuel during World War II for the Messerschmitt Me 163B (the first rocket-powered fighter plane). Within the U.S. space program, hydrazine was used on the 1970s Viking Mars program, and more recently in the Phoenix lander and Curiosity rover Mars missions, as ...