Boston – More than 100 million Americans suffer from chronic pain. But treating and studying chronic pain is complex and presents many challenges. Scientists have long searched for a method to objectively measure pain and a new study from Brigham and Women's Hospital advances that effort. The study appears in the January 2013 print edition of the journal Pain. "While we need to be cautious in the interpretation of our results, this has the potential to be an exciting discovery for anyone who suffers from chronic pain," said Marco Loggia, PhD, the lead author of the ...

On April 22, 2012 a very fast-moving fireball was observed over large parts of California and Nevada. Equivalent to four kilotons of TNT, the fireball was photographed, and recorded by video and by weather Doppler-radars. The photographs and videos helped to trace back its orbit to the far reaches of the outer part of the asteroid belt. The radar data helped meteorite hunters to recover a total of 77 specimens, with the first ones found only two days after the fall. The meteorite was named Sutter's Mill, after the location where it fell. (Interestingly, Sutter's Mill ...

ANN ARBOR, Mich. — From the moment a stroke occurs, patients must race against the clock to get treatment that can prevent lasting damage. Now, a new study shows the promise – and the challenges – of getting them state-of-the-art treatment safely at their local hospital, saving precious minutes. The results come from an effort that tested methods to improve delivery of a time-sensitive, clot-busting drug in stroke patients at 24 community hospitals across Michigan. To date, clot-busting treatment has been mostly used at larger hospitals. The research effort was coordinated ...

Durham, NC — Deep in the scrublands of Keoladeo National Park in northwest India, one thing was hard for biologist Jessica Yorzinski to ignore: It wasn't the heat. It wasn't the jackals. It was the squawks of peacocks in the throes of passion. From behind the trees in the distance, she could hear a loud two-part whoop, the distinctive call that male peacocks make right before mating. During the peacock courtship dance, a male announces that he's ready to make his move by dashing towards the object of his affection and emitting a singular squawk before mounting his ...

UNIVERSITY PARK, Pa. -- Not all video game players are destined for lives filled with failing relationships and dwindling friendships, according to Penn State researchers, who say that a lot depends on the role of the game-playing activity in the gamer's life. "There's a common stereotype that if you play video games, then you are a loner," said Benjamin Hickerson, assistant professor of recreation, parks and tourism management. "But it may have more to do with how a person is involved in gaming that determines how their social support is affected." In a study of people ...

Growing new blood vessels in the lab is a tough challenge, but a Johns Hopkins engineering team has solved a major stumbling block: how to prod stem cells to become two different types of tissue that are needed to build tiny networks of veins and arteries. The team's solution is detailed in an article appearing in the January 2013 print edition of the journal Cardiovascular Research. The article also was published recently in the journal's online edition. The work is important because networks of new blood vessels, assembled in the lab for transplanting into patients, ...

New York, NY (December 20, 2012) — Two recent experimental treatments — one involving skin-derived induced pluripotent stem (iPS) cell grafts, the other gene therapy — have been shown to produce long-term improvement in visual function in mouse models of retinitis pigmentosa (RP), according to the Columbia University Medical Center (CUMC) scientists who led the studies. At present, there is no cure for RP, the most common form of inherited blindness. "While these therapies still need to be refined, the results are highly encouraging," said Stephen H. Tsang, MD, PhD, associate ...

Cyclone Evan is no more than a remnant low pressure area in the South Pacific Ocean now. NOAA's GOES-15 satellite captured an image of the remnants from its fixed orbit in space on Dec. 20 that showed strong wind shear had basically blown the storm apart. The last official bulletin by the Joint Typhoon Warning Center was issued on Dec. 19 at 2100 UTC (4 p.m. EST/U.S. or 12:56 a.m. Fiji local time on Dec. 20). At that time, Evan's maximum sustained winds were still near 35 knots (40 mph/64.8 kph) and it had transitioned into an extra-tropical storm. It was located 400 ...

An oversized semi-trailer truck carrying NASA's Landsat Data Continuity Mission (LDCM) has arrived at its launch site at Vandenberg Air Force Base in California in preparation for launch. This NASA and U.S. Geological Survey mission will continue a 40-year record of measuring change on the planet from space. LDCM is the eighth satellite in the Landsat series, which began in 1972. It will extend and expand global land observations that are critical in many sectors, including energy and water management, forest monitoring, human and environmental health, urban planning, ...

PHILADELPHIA — The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, PhD and Weihua Li, co-first author, both from the Center for Resuscitation Sciences, Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, and Xiaowei Xu, Department of Pathology and Laboratory Medicine, appears in Molecular Cell. The findings were also highlighted in Nature and Science reviews. This new research shows ...

GAINESVILLE, Fla. — In the rain forests of the Congo, where mammals and birds are hunted to near-extinction, an impenetrable sound of buzzing insects blankets the atmosphere. Because it is a fairly inaccessible region with political unrest, much of the Congo's insect biodiversity remains largely undiscovered. In a new monographic book published this week in Zootaxa, researchers at the University of Florida and the Royal Museum of Central Africa in Belgium provide insect biodiversity information for this area in Central Africa that increasingly undergoes habitat destruction. ...

University of Toronto Faculty of Medicine researchers have uncovered a genetic basis for fundamental differences between humans and other vertebrates that could also help explain why humans are susceptible to diseases not found in other species. Scientists have wondered why vertebrate species, which look and behave very differently from one another, nevertheless share very similar repertoires of genes. For example, despite obvious physical differences, humans and chimpanzees share a nearly identical set of genes. The team sequenced and compared the composition of hundreds ...

Meteorites that had fallen from an asteroid impact that lit up the skies over California and Nevada in April are showing scientists just how complex an asteroid surface can be. A new study published in Science this week by an international team of researchers describes the speedy recovery of the meteorites and reports that this space rock is an unusual example from a rare group known as carbonaceous chondrites, which contain some of the oldest material in the solar system. The study of these meteorites and others like them could hold answers to unsolved mysteries about ...

CHESTNUT HILL, MA (Dec. 20, 2012) – The clock is ticking and you still haven't decided what to get that special someone in your life for the holidays. When it comes to those last-minute gift-buying decisions for family and close friends, intuition may be the best way to think your way through to that perfect gift. When faced with tough decisions, some people like to "trust their gut" and go with their intuition. Others prefer to take an analytical approach. Boston College Professor Michael G. Pratt, an expert in organizational psychology, says new research shows intuition ...

A meteorite that exploded as a fireball over California's Sierra foothills this past spring was among the fastest, rarest meteorites known to have hit the Earth, and it traveled a highly eccentric orbital route to get here. An international team of scientists presents these and other findings in a study published Friday, Dec. 21, in the journal Science. The 70-member team included nine researchers from UC Davis, along with scientists from the SETI Institute, NASA and other institutions. The researchers found that the meteorite that fell over Northern California on April ...

Little more than a decade ago, the United States imported much of its natural gas. Today, the nation is tapping into its own natural gas reserves and producing enough to support most of its current needs for heating and power generation, and is beginning to export natural gas to other countries. The trend is expected to continue, as new methods are developed to extract natural gas from vast unrecovered reserves embedded in shale. Natural gas can be used to generate electricity, and it burns cleaner than coal. "With petroleum reserves in decline, natural gas production ...

A new study co-authored by the Georgia Institute of Technology indicates that clay minerals, rocks that usually form when water is present for long periods of time, cover a larger portion of Mars than previously thought. In fact, Assistant Professor James Wray and the research team say clays were in some of the rocks studied by Opportunity when it landed at Eagle crater in 2004. The rover only detected acidic sulfates and has since driven about 22 miles to Endeavour Crater, an area of the planet Wray pinpointed for clays in 2009. The study is published online in the ...

ANN ARBOR, Mich. – Patients who quit smoking and took an aspirin and statin before undergoing treatment for blocked leg arteries were less likely to suffer a complication six months later, according to new research led by the University of Michigan Cardiovascular Center. But few patients made the lifestyle changes and were on recommended medical therapy that can relieve leg pain and cramping associated with peripheral arterial disease, or PAD. The registry findings were published online ahead of print in Circulation: Cardiovascular Interventions and reveal a dramatic ...

WINSTON-SALEM, N.C. – Dec. 20, 2012 – People with Type 2 diabetes have two to four times the risk of cardiovascular disease compared to people without the disease. The best way for doctors to predict which diabetes patients are at the greatest risk for heart disease is to use a coronary artery calcium (CAC) test in addition to the most commonly used assessment tool, according to researchers at Wake Forest Baptist Medical Center. Current medical guidelines recommend treating all diabetes patients as high risk, but the Wake Forest Baptist study found that CAC can identify ...

JUPITER, FL, December 20, 2012 – Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a new approach to alter the function of RNA in living cells by designing molecules that recognize and disable RNA targets. As a proof of principle, in the new study the team designed a molecule that disabled the RNA causing myotonic dystrophy. The study, published online ahead of print on December 20, 2012 by the journal Angewandte Chemie, reports the creation of small molecules that recognize disease-associated RNAs, targeting them for destruction. ...

The Wildlife Conservation Society (WCS) lauded U.S. Secretary of the Interior Ken Salazars announcement of a final management plan for the National Petroleum Reserve-Alaska (NPR-A) that balances wildlife conservation and energy development in the biggest public landscape in the country. The Integrated Activity Plan and Final Environmental Impact Statement (Final IAP/EIS) issued today by the Bureau of Land Management is the first comprehensive land management plan ever developed for the NPR-A. By protecting extensive coastal plain habitat around Teshekpuk Lake, and the ...

WASHINGTON— The black piranha and the extinct giant piranha, or megapiranha, have the most powerful bites of carnivorous fishes, living or extinct, once body size is taken into account, finds researchers in a paper recently published in Scientific Reports. The research paper, Mega-Bites: Extreme jaw forces of living and extinct piranhas, highlights the piranhas' specialized jaw morphology, which allows them to attack and bite chunks out of much larger prey. Guillermo Ortí, the George Washington University Louis Weintraub Professor of Biology in the Columbian College of ...

Putnam Valley, NY. (Dec. 20, 2012) – Using mesenchymal stromal cells derived from adipose (fat) tissues, genetically modified to express a bioluminescent marker, researchers in Italy have tracked cells after transplantation. The cells were followed from their injection into the spleen of mice modeling liver disease, to their characterization as "hepatic precursors," and to their subsequent migration through the spleen before engrafting at regenerating sites in the liver by bioluminescent imaging. Their study is described in a recent issue of Cell Transplantation (21:9), ...

Putnam Valley, NY. (Dec. 20, 2012) – When different types of cells are transplanted with the intent of having them aid in repairing central nervous system (CNS) trauma, what is the fate and function of those cells? A Belgian research team carried out research aimed at answering this question by determining how five varieties of cells - neural stem cells, mouse embryonic fibroblasts, dendritic cells, bone marrow mononuclear cells (BMMNCs) and splenocytes - functioned and survived after transplantation in the CNS. Their study is published in a recent issue of Cell Transplantation ...

Putnam Valley, NY. (Dec. 20, 2012) – A team of researchers from three medical institutions in Guangzhou, China, have found that iron oxide nanoparticles (INOPS) are a useful contrast agent for in vivo magnetic resonance tracking of transplanted human endothelial cells. However, the impact of INOPS on the cells varies with a number of factors including the INOPS load. They found that the percentage of iron-labeled cells was significantly lower after 48 hours post-transplantation than at 24 hours post-transplantation. They also found that high INOPS concentration can affect ...