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Advance in chromosomal evolution in sea cradles

Advance in chromosomal evolution in sea cradles
2012-12-12
The study of chromosome changes arisen during species evolution is a current and intriguing topic that evolutionary biology proposes. However, in several groups (for example, molluscs), and chitons in particular, chromosome studies are scarce, with a few species investigated and analyses performed mostly with simple methods. Only 2,5% of about 900 living species of chitons have been so far karyologically investigated, all of them in the same order (Chitonida). The authors note that the species of suborder Chitonina all have a karyotype of 2n=24 chromosomes, all biarmed, ...

'Smart stethoscope' advance in monitoring treatment of kidney stones

Smart stethoscope advance in monitoring treatment of kidney stones
2012-12-12
A new listening device, developed by scientists from the University of Southampton, is being used to monitor the effectiveness of the treatment of kidney stones - saving patients unnecessary repeat therapy and x-ray monitoring. If kidney stones cannot be dissolved by drugs, the favoured procedure is lithotripsy. Lithotripsy works by focusing thousands of shock waves onto the kidney stones in an effort to break them into pieces small enough to urinate out of the body or be dissolved by drugs. However, it is difficult to discover exactly when the treatment has succeeded ...

Rice, Texas Children's team creates biocompatible patch to heal infants with birth defects

2012-12-12
A painstaking effort to create a biocompatible patch to heal infant hearts is paying off at Rice University and Texas Children's Hospital. The proof is in a petri dish in Jeffrey Jacot's lab, where a small slab of gelatinous material beats with the rhythm of a living heart. Jacot, lead author Seokwon Pok, a postdoctoral researcher at Rice, and their tissue-engineering colleagues have published the results ofyears of effort to produce a material called a bioscaffold that could be sutured into the hearts of infants suffering from birth defects. The scaffold, seeded with ...

Climate modelers see possible warmer, wetter Northeast winters by 2070

2012-12-12
AMHERST, Mass. – A new high-resolution climate study by University of Massachusetts Amherst climate scientists, the first to apply regional climate models to examine likely near-term changes in temperature and precipitation across the Northeast United States, suggests temperatures are going to be significantly warmer in all seasons in the next 30 years, especially in winter. Also, they project that winters will be wetter, with more rain likely than snow. Writing in the current issue of the Journal of Geophysical Research, Michael Rawlins and Raymond Bradley of the Climate ...

UGA researchers find algal ancestor is key to how deadly pathogens proliferate

2012-12-12
Athens, Ga. – Long ago, when life on Earth was in its infancy, a group of small single-celled algae propelled themselves through the vast prehistoric ocean by beating whip like tails called flagella. It's a relatively unremarkable tale, except that now, more than 800 million years later, these organisms have evolved into parasites that threaten human health, and their algal past in the ocean may be the key to stopping them. The organisms are called apicomplexa, but people know them better as the parasites that cause malaria and toxoplasmosis, serious diseases that infect ...

Ultra-short laser pulses control chemical processes

Ultra-short laser pulses control chemical processes
2012-12-12
This press release is available in German. Chemical reactions occur so quickly that it is completely impossible to observe their progress or to control them using conventional methods. However, new developments in electrical engineering and quantum technology enable us to achieve a more exact understanding and improved control of the behaviour of atoms and molecules. At the TU Vienna, scientists have succeeded in influencing the splitting of large molecules with up to ten atoms using ultra-short laser pulses. The flash of light which splits molecules Splitting a ...

Older and younger chronic leukemia patients may need different therapy

2012-12-12
People who develop chronic lymphocytic leukemia (CLL) are typically age 65 and older, but participants in CLL clinical trials are usually several years younger; The age of CLL patients is not usually considered when determining treatment; This study suggests that older and younger CLL patients require different therapy. COLUMBUS, Ohio – Doctors should use different therapies when treating older and younger patients with chronic lymphocytic leukemia, according to a new study led by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. ...

Researchers shed light on the workings of the body's immune response

2012-12-12
Researchers from Queen Mary, University of London have discovered that two proteins which are believed to play a key role in controlling the body's immune response are found in lower levels in T lymphocytes from patients with multiple sclerosis (MS). The study found that MS patients' T lymphocytes – types of white blood cells which play an important role in the immune system – were defective at producing the proteins and that this was associated with increased levels of molecules which promote inflammation. The findings are reported in the Journal of Immunology¹. The ...

Can algae-derived oils support large-scale, low-cost biofuels production?

Can algae-derived oils support large-scale, low-cost biofuels production?
2012-12-12
New Rochelle, NY, December 12, 2012—ExxonMobil and many other energy companies are investing hundreds of millions of dollars to develop transportation biofuels from renewable resources such as the oil or hydrocarbons produced by microalgae. As global supplies of fossil fuels continue to shrink, biofuels derived from algae represent one promising source of low-cost, scalable renewable energy. The feasibility and economic projections for large-scale biofuels production from microalgae are examined in a Review article and accompanying Commentary published in Disruptive Science ...

Novel test identifies patients most likely to benefit from ALK inhibition therapy

2012-12-12
Philadelphia, PA, December 12, 2012 – Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients are highly responsive to ALK-specific kinase inhibitors such as crizotinib. However, current diagnostic tests have limitations. Researchers have now developed and tested a promising new method for screening ALK fusions in NSCLC. This new diagnostic assay offers a cost-effective and easy-to-perform alternative ...

Frog-in-bucket-of-milk folklore leads to potential new antibiotics

2012-12-12
Following up on an ancient Russian way of keeping milk from going sour — by putting a frog in the bucket of milk — scientists have identified a wealth of new antibiotic substances in the skin of the Russian Brown frog. The study appears in ACS' Journal of Proteome Research. A. T. Lebedev and colleagues explain that amphibians secrete antimicrobial substances called peptides through their skin. These compounds make up the majority of their skin secretions and act as a first line of defense against bacteria and other microorganisms that thrive in the wet places frogs, toads, ...

A promising clinical trial to reduce the severity of autistic disorders

2012-12-12
This press release is available in French. Although this therapy is not curative, it nevertheless reduced the autistic disorders' severity in three-quarters of the children. The researchers have filed a request for authorisation to perform a multi-centre European clinical trial in order to determine more precisely the population concerned by this therapy. Details of this work have been published in the Translational Psychiatry review dated 11 December 2012. Contribution made by the fundamental research on neuronal chloride Previous work carried out by the team of ...

New twist on using biomass for perfume, cosmetic, personal care products

2012-12-12
In a new approach for tapping biomass as a sustainable raw material, scientists are reporting use of a Nobel-Prize-winning technology to transform plant "essential oils" — substances with the characteristic fragrance of the plant — into high-value ingredients for sunscreens, perfumes and other personal care products. The report on the approach, which could open up new economic opportunities for tropical countries that grow such plants, appears in the Journal of the American Chemical Society. Deryn Fogg, Eduardo dos Santos and colleagues explain that breaking down plant ...

New geometries: Researchers create new shapes of artificial microcompartments

2012-12-12
In nature, biological functions are often carried out in tiny protective shells known as microcompartments, structures that provide home to enzymes that convert carbon dioxide into energy in plant cells and to viruses that replicate once they enter the cell. Most of these shells buckle into an icosahedron shape, forming 20 sides that allow for high interface with their surroundings. But some shells — such as those found in the single-celled Archaea or simple, salt-loving organisms called halophiles —break into triangles, squares, or non-symmetrical geometries. While these ...

Scientists train honey bees to stick out their tongues

Scientists train honey bees to stick out their tongues
2012-12-12
Honey bees are a highly organized, social species, as demonstrated by their complex colonies and the geometric structure of their hives. For hive building, the honey bee strongly relies on its tactile sense, and a new video-article in JoVE (Journal of Visualized Experiments) illustrates a novel tactile conditioning experiment using honey bees. The technique, presented by the lab of Dr. Volker Dürr of Bielefeld University, trains honey bees to stick out their tongues when their antennae touch an object. This procedure allows researchers to analyze how changes in antennal ...

A second ascent of chemistry's Mt. Everest

2012-12-12
In science's equivalent of ascending Mt. Everest, researchers are reporting success in one of the most difficult challenges in synthetic chemistry — a field in which scientists reproduce natural and other substances from jars of chemicals in a lab. The feat, reported in the Journal of the American Chemical Society, involved synthesis of a rare substance with promising in vitro anti-cancer effects found naturally in tiny amounts in a Chinese medicinal herb. Samuel J. Danishefsky and Feng Peng explain that maoecrystal V occurs naturally in a plant growing in China's Yunnan ...

Will climate change cause water conflict?

2012-12-12
International researchers from 14 institutions met in Nicosia (Cyprus) on the 10th and 11th of December to present and debate the results of studies on water, conflict and security conducted in the past three years in a variety of locations in the Mediterranean, Middle East and Sahel under the CLICO research project. The CLICO project explored the social dimensions of climate change and in particular, conflicts related to water, and the threats this may pose for national and human security. The project was led by the Institute for Environmental Science and Technology (ICTA) ...

Relocating elephants fails to decrease human–wildlife conflict

2012-12-12
Human–elephant conflict in Sri Lanka kills more than 70 humans and 200 Asian elephants every year. One of the most common tools in combating these conflicts is moving the elephants into ranges away from humans, often into national parks. This is done in hopes of avoiding problems that include elephants raiding crops, breaking into homes and injuring or killing people. But according to a new study to be published Dec. 7 in PLOS ONE by the Smithsonian Conservation Biology Institute, the Centre for Conservation and Research in Sri Lanka and the Department of Wildlife Conservation ...

Cane toads can be stopped

2012-12-12
It may be possible to stop the spread of can toads into new areas of Australia according to new research published today in the Journal of Applied Ecology. One of the lead authors of the study, James Cook University's Dr Ben Phillips, said that their work, which involved an international team of scientists, showed that artificial waterbodies installed by graziers acted as critical stepping-stones for the toad invasion. "By removing these waterbodies in key locations it is possible to halt the spread of toads," he said. Cane toads are currently spreading into the vast ...

Emerging virus in raccoons may provide cancer clues

2012-12-12
Rare brain tumors emerging among raccoons in Northern California and Oregon may be linked to a previously unidentified virus discovered by a team of researchers, led by scientists from the University of California, Davis. Their findings, published today in the journal Emerging Infectious Diseases, could lead to a better understanding of how viruses can cause cancer in animals and humans. Necropsies conducted since March 2010 by scientists at the UC Davis School of Veterinary Medicine and UC Davis-led California Animal Health and Food Safety Laboratory found brain tumors ...

Researchers find algal ancestor is key to how deadly pathogens proliferate

2012-12-12
Long ago, when life on our planet was in its infancy, a group of small single-celled algae floating in the vast prehistoric ocean swam freely by beating whip-like tails, called flagella. It's a relatively unremarkable tale, except that now, over 800 million years later, these organisms have evolved into parasites that threaten human health, and their algal past in the ocean may be the key to stopping them. The organisms are called Apicomplexa, but are better known as the parasites that cause malaria and toxoplasmosis—serious diseases that infect millions of people every ...

New method quantifies uncertainty in estimates of child mortality rates

2012-12-12
Measures of uncertainty should be taken into account when estimating progress towards Millennium Development Goal 4 (to reduce the mortality rate of children under 5 years by two thirds from the 1990 level by 2015) in order to give more accurate assessments of countries' progress, according to a study published in this week's PLOS Medicine. Leontine Alkema and Jin Rou New from the National University of Singapore used a statistical method called bootstrapping to calculate uncertainty intervals for the estimates of mortality rates in children aged under 5 years and the ...

Prevalence of visual impairment in US increases

2012-12-12
CHICAGO – The prevalence of nonrefractive visual impairment (not due to need for glasses) in the U.S. has increased significantly in recent years, which may be partly related to a higher prevalence of diabetes, an associated risk factor, according to a study in the December 12 issue of JAMA. "It is estimated that more than 14 million individuals in the United States aged 12 years and older are visually impaired ( END ...

Taxes on sugary drinks and high fat foods could improve health

2012-12-12
Taxes on soft drinks and foods high in saturated fats and subsidies for fruit and vegetables could lead to beneficial dietary changes and potentially improve health, according to a study by experts from New Zealand published in this week's PLOS Medicine. Helen Eyles and colleagues from the University of Auckland and the University of Otago (Wellington) reached these conclusions by reviewing all relevant modelling studies that investigated the association between food pricing strategies, food consumption and chronic diseases (often referred to as non-communicable diseases, ...

Combination therapy may help decrease sleep apnea symptoms at higher altitudes

2012-12-12
CHICAGO – For individuals with obstructive sleep apnea traveling to higher altitudes (which may exacerbate symptoms), use of a combination therapy resulted in improvement in symptoms including reduced insomnia and better control of sleep apnea, according to a preliminary study published in the December 12 issue of JAMA. As travel to the mountains for professional and recreational activities is increasingly popular, involving millions of persons worldwide, the estimated number of patients with obstructive sleep apnea (OSA) among mountain tourists is also high, and may ...
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