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TLI investigator Dr. Nicholas Jenzjowsky receives NIH/NIAID grant to investigate the neural regulation of asthma

TLI investigator Dr. Nicholas Jenzjowsky receives NIH/NIAID grant to investigate the neural regulation of asthma
2024-03-21
In a significant stride for respiratory medicine, Lundquist Institute (TLI) investigator Nicholas Jendzjowsky, PhD, has been awarded a prestigious grant from the National Institute of Health/National Institute of Allergy and Infectious Diseases (NIH/NIAID). This grant, totaling $298,800, not only underscores TLI's commitment to pioneering research and excellence in respiratory medicine and exercise physiology but also recognizes Dr. Jendzjowsky's expertise and the importance of his research. The ...

Doctors’ pay in England has declined by 25% since 2008

2024-03-21
Doctors’ pay in England has declined by 25% since 2008 Independent analysis shows doctors’ salary erosion far outstrips other UK workers Doctors describe how they struggle to afford everyday essentials Trainee eye surgeon quit after worry over gas bill As doctors in England enter their 13th month of industrial action, an independent analysis of their pay confirms that the real terms value of their salaries has declined by a quarter in the 15 years since their pay was frozen. The analysis – conducted for The BMJ by the Office of Health Economics (OHE), an independent health economics research organisation – found that across ...

NIH grant funds research on work-related asthma among nurses

NIH grant funds research on work-related asthma among nurses
2024-03-21
A researcher at the University of Arizona Mel and Enid Zuckerman College of Public Health received a $750,000 National Institutes of Health grant to study the asthma risks associated with the use of cleaning and disinfecting products among nurses. Cleaning processes in health care facilities involve an inherent “risk-risk tradeoff.” Increased use of cleaning and disinfection products leads to increased work-related asthma risks and simultaneously a decrease in occupational-infection risks. Preliminary survey data indicate that nurses are generally willing to increase infection risks to maintain lower asthma risks if they think they will recover. “Translating ...

AI tool predicts risk of side effects after surgery and radiotherapy in breast cancer patients

AI tool predicts risk of side effects after surgery and radiotherapy in breast cancer patients
2024-03-21
Milan, Italy: A team of international researchers have developed an artificial intelligence (AI) tool that can predict which breast cancer patients may be at risk of side effects after surgery and radiotherapy.   Dr Tim Rattay told the 14th European Breast Cancer Conference (EBCC14) in Milan today (Thursday) that the tool will be tested in a clinical trial that will start recruiting in the last quarter of this year in three countries: France, The Netherlands and the UK.   “It is an explainable AI tool, which means that it shows the reasoning behind its decision-making. This makes it ...

Adding ribociclib to hormone therapy reduces the risk of breast cancer recurrence

2024-03-20
A new treatment approach that combines a targeted therapy drug with hormone therapy significantly increased the amount of time a person with stage 2 or 3 HR-positive, HER2-negative early breast cancer lives without the cancer returning, according to a new study co-led by UCLA Health Jonsson Comprehensive Cancer Center investigators. The team found adding ribociclib, a drug that belongs to a class of CDK4/6 inhibitors, to standard hormone therapy not only improved invasive-free survival in women with this type of early-stage breast cancer, but also improves distant disease-free survival and recurrence-free survival. The results were published today in the New England ...

Social isolation linked to biological age gap, higher mortality rate

2024-03-20
ROCHESTER, Minn. — A new study from Mayo Clinic finds that socially isolated people are more likely to show signs of being biologically older than their age and more likely to die from a variety of causes. The research, published in the Journal of the American College of Cardiology: Advances, suggests that social connection plays an important role in overall physical health and longevity, and it should be addressed as a necessary part of the social determinants of health. To investigate the role of social contact in biological aging, the ...

New commentary: Combatting digital redlining is imperative for advancing health equity

2024-03-20
Broadband plays a critical role in most aspects of modern-day life, yet over 42 million Americans still lack access to high-speed Internet. This digital divide is driven by “digital redlining”—discriminatory disinvestment in broadband infrastructure that disproportionately affects people of color, low-income communities, and rural populations, worsening disparities in access to healthcare, social services, education, and employment for these populations. Addressing digital redlining and the digital divide is imperative for ...

Drug-pricing program improved prostate cancer treatment adherence

2024-03-20
ANN ARBOR, Michigan — Prostate cancer patients receiving care at hospitals that are part of a special drug-pricing program were more likely to stick to their prescription drug therapy than patients at other hospitals, according to a study from researchers at the University of Michigan’s Rogel Cancer Center and Institute for Healthcare Policy and Innovation.   The 340B Drug Pricing Program is a federal program that requires the pharmaceutical industry to provide a discount on the cost of drugs to participating hospitals who serve a disproportionate number of Medicare and Medicaid patients. The program was started to enable hospitals to stretch scarce resources, ...

Prenatal exposure to antiseizure medication topiramate may not increase children’s risk of autism spectrum disorder

2024-03-20
Embargoed for release: Wednesday, March 20, 5:00 PM ET Key points: In a study of 4.3 million pregnant women and their children, prenatal exposure to topiramate, an antiseizure medication used to treat epilepsy, bipolar disorder, and migraines, was not associated with additional risk of the children developing autism spectrum disorder (ASD). Consistent with previous research, the study also found that prenatal exposure to valproate and lamotrigine—two other antiseizure medications—were associated with ...

Experimental gene therapy for giant axonal neuropathy shows promise in NIH clinical trial

2024-03-20
An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health (NIH). Currently, there is no treatment for GAN and the disease is usually fatal by 30 years of age. Fourteen children with GAN, ages 6 to 14 years, were treated with gene transfer therapy at the NIH Clinical Center and then followed for about six years to assess safety. Results ...

TIFRH study reports scalable and cost-effective method to assemble a safer and durable lithium metal battery

TIFRH study reports scalable and cost-effective method to assemble a safer and durable lithium metal battery
2024-03-20
Lithium metal batteries (LMBs) can provide nearly 10 times higher energy density compared to the present Lithium-ion batteries (LIBs) and hence are identified as one of the potential future storage systems. However, LMBs pose certain safety concerns and cannot be used for fast-charging applications. Uncontrolled dendrite formation, leading to excessive heating and battery short circuit is one of the critical challenges of its advancement. Researchers have previously attempted to address the safety concerns in LMBs but with methods that were laboursome and money/time intensive. T. N. Narayanan’s lab at the Tata Institute ...

Pediatric cancer research foundation expands executive leadership team

Pediatric cancer research foundation expands executive leadership team
2024-03-20
IRVINE, CA, March 20, 2024 --The Pediatric Cancer Research Foundation (PCRF), a nonprofit focused on transforming pediatric cancer care by funding research breakthroughs, today announced the expansion of its leadership team. Executive Director Jeri Wilson, who has led the organization for 12 years, will step into the newly created role of Vice President of Development, Principal Gifts.  Danielle Fragalla, a known nonprofit leader in California, will become Chief Executive Officer. In the 12 years Ms. Wilson has led the Foundation, it has grown from a grassroots ...

Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay

Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay
2024-03-20
“These results suggest strong potential for clinical use of the assay in ctDNA monitoring of solid tumor cancers.” BUFFALO, NY- March 20, 2024 – A new research paper was published in Oncotarget's Volume 15 on March 14, 2024, entitled, “Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay.” In this new study, researchers Josette Northcott, Gabor Bartha, Jason Harris, Conan Li, Fabio C.P. Navarro, Rachel Marty Pyke, Manqing Hong, Qi Zhang, Shuyuan Ma, Tina X. Chen, Janet Lai, Nitin Udar, Juan-Sebastian Saldivar, Erin Ayash, ...

Research suggests how turbulence can be used to generate patterns

2024-03-20
The turbulent motion of a tumbling river or the outflow from a jet engine is chaotic: that is, it contains no obvious pattern. But according to a new study, regular patterns can emerge from the turbulent motion of fluids. What you need is an intriguing property called “odd viscosity” that arises under certain conditions,  such as when the particles in the fluid all spin in the same direction. Though it’s a specialized circumstance, there are many contexts in nature where a version of this effect may exist, such as in the ...

Treating anxiety, depression significantly impacts heart disease outcomes

2024-03-20
COLUMBUS, Ohio — Treating anxiety and depression significantly reduced emergency room visits and rehospitalizations among people with heart disease, according to a study by researchers at The Ohio State University Wexner Medical Center.  “For patients hospitalized for coronary artery disease or heart failure and who had diagnoses of anxiety or depression, treatment with psychotherapy, medication or both was associated with as much as a 75% reduction in hospitalizations or emergency room visits. In some cases, there was a reduction in death,” said lead study author Philip Binkley, MD, executive ...

University of Oklahoma-led study receives best paper award from unconventional resources conference

University of Oklahoma-led study receives best paper award from unconventional resources conference
2024-03-20
A study led by University of Oklahoma researchers has been selected for a 2023 best paper award in the Advanced Formation Evaluation technical program theme from the Unconventional Resources Technology Conference. The study examined how clay and kerogen, two different components within rocks, respond to nuclear magnetic resonance, or NMR, a technique used to assess the amount of fluids within rocks. Many fluids found within rocks contain hydrogen, and knowing whether and how much hydrogen is available in the subsurface is an important facet of oil and gas exploration. Researchers found that higher NMR frequencies improved data acquisition efficiency. As a result of this study, a ...

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet
2024-03-20
“This discovery unveils a potential novel molecular target for therapeutic strategies against hepatic steatosis during the aging process [...]” BUFFALO, NY- March 20, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5, entitled, “FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet.” FoxO6, an identified factor, induces hyperlipidemia and hepatic steatosis during aging by activating hepatic ...

Dr. Cochav Elkayam-Levy awarded the Israel Prize for her work to raise awareness of Hamas’ crimes against humanity against Israeli women, children, men, and families

Dr. Cochav Elkayam-Levy awarded the Israel Prize for her work to raise awareness of Hamas’ crimes against humanity against Israeli women, children, men, and families
2024-03-20
Dr. Cochav Elkayam-Levy, of the Hebrew University of Jerusalem awarded the Israel Prize in the field of Solidarity (Arvut Hadadit) for her tireless work to raise awareness and acknowledgement to the crimes committed by Hamas on and following October 7th against Israeli women, children, men and families. Elkayam-Levy established the “Civil Commission on October 7th Crimes by Hamas against Women and Children”, aimed at giving voice to the victims and their families and raising awareness of the concerning developments in war crimes against women, children, men and families on and after October 7th and raising support for this cause. Dr. Cochav Elkayam-Levy: ...

Partisanship influences consumer confidence, spending more than expected

Partisanship influences consumer confidence, spending more than expected
2024-03-20
A new study from the University of Florida's Bureau of Economic and Business Research (BEBR) has found that national elections have a greater impact on consumer sentiment and spending intentions than previously thought, especially during transitions of power between political parties. Led by Hector Sandoval, director of the Economic Analysis Program and research assistant professor at BEBR, the study draws on years of meticulous observation and analysis of monthly sentiments data collected by the UF Survey Research Center. Despite the wealth of data available ...

AI can now detect COVID-19 in lung ultrasound images

2024-03-20
Artificial intelligence can spot COVID-19 in lung ultrasound images much like facial recognition software can spot a face in a crowd, new research shows. The findings boost AI-driven medical diagnostics and bring health care professionals closer to being able to quickly diagnose patients with COVID-19 and other pulmonary diseases with algorithms that comb through ultrasound images to identify signs of disease. The findings, newly published in Communications Medicine, culminate an effort that started early in the pandemic when clinicians needed tools to rapidly assess legions of patients in overwhelmed emergency rooms. “We developed ...

Is the burden of neurologic disease higher after influenza or COVID-19?

2024-03-20
EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, MARCH 20, 2024 MINNEAPOLIS – People who have an influenza infection are more likely to need medical care for neurologic disorders within the next year than people who have a COVID-19 infection, according to a study published in the March 20, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study, funded by the American Academy of Neurology, looked at people who were hospitalized with either influenza or COVID-19. The study did not look specifically at outcomes ...

Scientists find one of the most ancient stars that formed in another galaxy

2024-03-20
The first generation of stars transformed the universe. Inside their cores, simple hydrogen and helium fused into a rainbow of elements. When these stars died, they exploded and sent these new elements across the universe. The iron running in your veins and the calcium in your teeth and the sodium powering your thoughts were all born in the heart of a long-dead star.  No one has been able to find one of those first generation of stars, but scientists have announced a unique finding: a star from the second generation that originally formed in a different galaxy from ours. “This ...

Researchers add swept illumination to open-top light-sheet microscope

Researchers add swept illumination to open-top light-sheet microscope
2024-03-20
Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more practical for nondestructive 3D pathology. 3D pathology is being explored as an alternative to traditional slide-based histology because it can provide detailed 3D insights into pathological structures and cellular interactions without altering the tissue. This approach makes it possible to analyze complex 3D tissue structures and to image thick tissues, which is not possible with slide-based methods. The researchers used their improved open-top ...

High-quality microwave signals generated from tiny photonic chip

High-quality microwave signals generated from tiny photonic chip
2024-03-20
In a new Nature study, Columbia Engineering researchers have built a photonic chip that is able to produce high-quality, ultra-low-noise microwave signals using only a single laser. The compact device — a chip so small, it could fit on a sharp pencil point — results in the lowest microwave noise ever observed in an integrated photonics platform. The achievement provides a promising pathway towards small-footprint ultra-low-noise microwave generation for applications such as high-speed communication, atomic clocks, and autonomous vehicles. The challenge Electronic devices for global navigation, wireless communications, radar, and ...

OFC 2024 brings innovations from leading global organizations and cutting-edge tech demonstrations to California

OFC 2024 brings innovations from leading global organizations and cutting-edge tech demonstrations to California
2024-03-20
SAN DIEGO—A wave of innovation is hitting California as the Optical Fiber Communications Conference and Exhibition (OFC) gears up to showcase the latest breakthroughs in optical communications and networking. OFC will take place at the San Diego Convention Center from 24 to 28 March 2024 drawing industry leaders, experts, academia, media, analysts and students from around the world to explore the latest in optical technology. Innovative advancements in industrial technologies, as well as research in 800ZR, Coherent PON, Linear Pluggable Optics (LPO), multicore fiber, AI and ...
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