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Happiness poll: Democrats and Diden voters report more happiness than GOP and Trump supporters

Happiness poll: Democrats and Diden voters report more happiness than GOP and Trump supporters
2024-03-19
Voters of the Democratic party and U.S. President Joe Biden are happier than voters for the Republican party and former U.S. President Donald Trump, while older and wealthier adult voters are happier than younger and less-wealthy ones, according to a new Florida Atlantic University PolCom and Mainstreet Research happiness poll released today in advance of the United Nation’s International Day of Happiness on March 20. “Happiness is important to understand as it influences the well-being and satisfaction of citizens, which in turn shapes their voting behavior,” said Carol Bishop Mills, Ph.D., FAU’s communication professor, PolCom co-director, and expert in relational ...

Mass General Brigham researchers develop AI foundation models to advance pathology

Mass General Brigham researchers develop AI foundation models to advance pathology
2024-03-19
Foundation models, advanced artificial intelligence systems trained on large-scale datasets, hold the potential to provide unprecedented advancements for the medical field. In computational pathology (CPath), these models may excel in diagnostic accuracy, prognostic insights, and predicting therapeutic responses. Researchers at Mass General Brigham have designed the two of the largest CPath foundation models to date: UNI and CONCH. These foundation models were adapted to over 30 clinical, diagnostic needs, including ...

Colorectal cancer screening in Araba (Basque Country)

2024-03-19
Background and objectives Colorectal cancer (CRC) is the third most common malignancy worldwide. The average age at diagnosis of CRC is around 70 years old. This study aimed to assess the prevalence of asymptomatic CRC and premalignant lesions in the colon in OSI Araba.   Methods This study included individuals aged 50–69 who were admitted to OSI Araba Health Centers. It spanned from the start of CRC screening through fecal occult blood test immunological analysis in 2009 to the publication of the latest updated data in 2021.   Results An average of 90.98% of participants obtained a definitive result. Specifically, ...

Primary care telemedicine linked with fewer antibiotics for children than direct-to-consumer telemedicine

Primary care telemedicine linked with fewer antibiotics for children than direct-to-consumer telemedicine
2024-03-19
New research from the University of Pittsburgh and UPMC shows that telemedicine visits conducted for children with primary care providers (PCPs) are associated with fewer antibiotic prescriptions than telemedicine visits with virtual-only direct-to-consumer (DTC) companies.   The findings, published in JAMA Network Open, highlight the importance of supporting integrated telemedicine within the primary care setting and the potential challenges and limitations of delivering virtual-only acute care to children. “Respiratory tract infections are one of the most common reasons that kids receive antibiotics, ...

CABI-led study shows benefits of chatgroups to human health can be replicated in plant health

CABI-led study shows benefits of chatgroups to human health can be replicated in plant health
2024-03-19
A CABI-led study has revealed that there is evidence of the benefits of chatgroups to human health which can also be replicated in plant health. The research analysed the opportunities and pitfalls of using chatgroups for plant health systems and examined the conditions for strengthening chatroom functions. It also considered the possibility of replicating reported successes in healthcare settings to plant health systems. The scientists from CABI, who were joined by colleagues including from the Knowledge, Technology and ...

Spectroscopy and theory shed light on excitons in semiconductors

Spectroscopy and theory shed light on excitons in semiconductors
2024-03-19
From solar panels on our roofs to the new OLED TV screens, many everyday electronic devices simply wouldn’t work without the interaction between light and the materials that make up semiconductors. A new category of semiconductors is based on organic molecules, which largely consist of carbon, such as buckminsterfullerene. The way organic semiconductors work is largely determined by their behaviour in the first few moments after light excites electrons, forming “excitons” in the material. Researchers from the Universities of Göttingen, Graz, ...

Assessing the impact of malaria interventions through routine sampling of pregnant women

2024-03-19
Genetic diversity of the malaria parasite in pregnant women and children declined in an area targeted for malaria elimination in Mozambique, according to a study led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by “la Caixa” Foundation and the Manhiça Health Research Centre (CISM). The findings, published in Nature Communications, highlight the added value of routine sampling of pregnant women as a cost-effective strategy to enhance genomic surveillance of the parasite and detect changes in transmission within the community. Genomic surveillance of the malaria parasite P. falciparum is essential ...

Drug candidate may ‘unmask’ latent HIV-infected cells, mark them for destruction

Drug candidate may ‘unmask’ latent HIV-infected cells, mark them for destruction
2024-03-19
​​​​​​PITTSBURGH, March 19, 2024 – University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system. The discovery, described today in Cell Chemical Biology, reveals a potential path to eliminate the viral reservoir that cannot be cleared with existing antiretroviral drugs. This reservoir is what prevents people from being completely cured of HIV even when their viral load is undetectable in standard tests. “We ...

Epidemic of fatal prion disease kuru likely led to migration of women in the Eastern Highlands of Papua New Guinea

2024-03-19
In the most comprehensive genetic study of the people living in the Eastern Highlands of Papua New Guinea to date, researchers from Papua New Guinea and the U.K. revealed the complex population structure and migration patterns of the communities in the region. The results, published March 19 in The American Journal of Human Genetics, lay the foundation for future research on the fatal disease kuru—a disease transmitted during traditional anthropophagic mortuary practices— that devastated the area in the 20th century. “We navigated one of the most complex landscapes possible in terms of geographical, cultural and linguistic diversity and set the scene ...

Biomarkers of the middle-aged brain predict cognitive health in old age

2024-03-19
The middle-aged brain could provide a window into future cognitive health, researchers write in a review publishing March 19 in the journal Trends in Neurosciences. The team reviewed evidence from human and animal studies suggesting that middle age—commonly considered as the period between 40 and 60 or 65 years of age—marks a shift in brain aging. They argue that more research should be dedicated to middle age, a period of life that is historically understudied. “Middle age is associated with specific and modifiable risk factors for future dementia risk,” write the authors, who include neuroscientist Yvonne Nolan ...

USPSTF statement on primary care interventions to prevent child maltreatment

2024-03-19
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to assess the balance of benefits and harms of primary care interventions to prevent child maltreatment. Child maltreatment, which includes child abuse and neglect, can have profound effects on health, development, survival, and well-being throughout childhood and adulthood. The prevalence of child maltreatment in the U.S. is uncertain and likely underestimated. In 2021, an estimated 600,000 children were identified by Child Protective Services as experiencing abuse ...

Stroke risk after COVID-19 bivalent vaccination among US older adults

2024-03-19
About The Study: Among 11,000 Medicare beneficiaries age 65 or older who experienced stroke after receiving either brand of the COVID-19 bivalent vaccine, there was no evidence of a significantly elevated risk for stroke during the days immediately after vaccination.  Authors: Yun Lu, Ph.D., of the Food and Drug Administration in Silver Spring, Maryland, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2024.1059) Editor’s ...

New ultrasound technology may revolutionize respiratory disease diagnoses

New ultrasound technology may revolutionize respiratory disease diagnoses
2024-03-19
WASHINGTON, March 19, 2024 – The thorax, the part of the body between the neck and abdomen, provides medical professionals with a valuable window into a patient’s respiratory health. By evaluating sound vibrations produced by the airflow induced within the lungs and bronchial tree during normal breathing as well as those produced by the larynx during vocalizations, doctors can identify potential disease-related abnormalities within the respiratory system. But, among other shortcomings, common respiratory assessments can be subjective and are only as good as the quality ...

Decision aid helps patients make informed decisions about sterilization

Decision aid helps patients make informed decisions about sterilization
2024-03-19
Researchers at the University of Pittsburgh have developed a simple, web-based decision aid called My Decision/Mi Decisión that helps empower pregnant individuals who are considering tubal sterilization to make informed decisions about their reproductive health, according to a new study published today in JAMA Network Open. With significant misunderstandings surrounding sterilization, the Pitt researchers can now offer comprehensive, engaging and accessible information to help support individuals as they make the best contraceptive decisions for themselves. “When patients are making decisions about their health and fertility, we want to make certain ...

New spatial profiling approach maps out discoveries for future brain research

New spatial profiling approach maps out discoveries for future brain research
2024-03-19
An estimated one in six people suffer from a brain disorder worldwide, according to the American Brain Foundation. Current research has provided some insight into cell-communication inside the brain, but there are still a lot of unknowns surrounding how this crucial organ functions. What if there was a comprehensive map that took into consideration not just the biology of the brain, but the specific location where the biology occurs? Researchers in the College of Engineering have developed a powerful, cost-effective method to do just that.  Chang Lu, the Fred W. Bull Professor of Chemical Engineering, has been leading ...

Family out-of-pocket expenditure on dental care

2024-03-19
Alexandria, VA, USA – A study aiming to determine if poorer families pay more for dental care as a proportion of their total income than richer families. was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.  The abstract, ...

11th ARDD Meeting Announces initial stellar speaker lineup and XPRIZE Healthspan Team Summit

11th ARDD Meeting Announces initial stellar speaker lineup and XPRIZE Healthspan Team Summit
2024-03-19
According to the United Nations, the proportion of people aged over 65 now outnumber children younger than 5. The enormous growth in the elderly population is posing a socioeconomic challenge to societies worldwide, and necessitates new sweeping interventions for age-associated diseases. This year we have an incredibly exciting program with global thought-leaders sharing their latest insights into aging and how we target the aging process ensuring everyone lives a healthier and longer life. Welcome to the 11th Aging Research and Drug Discovery Meeting. This year, ARDD is proud to be a partner of XPRIZE ...

Cell therapy approach harnesses the immune system in a different way to stop cancer

Cell therapy approach harnesses the immune system in a different way to stop cancer
2024-03-19
NOTE TO EDITORS: High-resolution b-roll, soundbites and images are available for download at https://bit.ly/3PfnX5Y  COLUMBUS, Ohio – A new cancer treatment that uses a person’s own immune cells has been approved by the U.S. Food and Drug Administration (FDA) for treating the most dangerous type of skin cancer. Now this form of cellular therapy (tumor-infiltrating lymphocyte – or TIL therapy) is showing promise in advanced lung cancers through clinical trials underway at The Ohio State University Comprehensive Cancer ...

Artificial intelligence algorithms for understanding the determinants of oral health

2024-03-19
Alexandria, VA, USA – A study aiming to use AI and predictive models to forecast the likelihood of permanent tooth loss, as an indicator of overall oral health, based on various behavioral and lifestyle factors was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.  The abstract, “Artificial Intelligence Algorithms for Understanding the Determinants of Oral Health” was presented during ...

Predicting oral cancer-related mortality among adults using machine learning approach

2024-03-19
Alexandria, VA, USA – A study aiming to predict oral cancer-related mortality among adults in the United States and identify the predictors of oral cancer-related mortality using the Machine Learning Approach. was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA. The abstract, “Predicting Oral Cancer-Related Mortality among Adults Using Machine Learning Approach” was presented ...

Harnessing biomaterial-based FTY720 immunotherapy to accelerate oral wound healing

2024-03-19
Alexandria, VA, USA – A study aiming to deliver Fingolimod (FTY720) loaded polymer scaffolds to enhance oral wound healing by modulating pro-regenerative immune cell migration associated with improved vascularization and tissue remodeling was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA. The abstract, “Harnessing Biomaterial-Based ...

Oral health behaviors associated with mental health disorders

2024-03-19
Alexandria, VA, USA – A study aiming to examine oral hygiene self-care behavior among patients with self-reported mental health disorders was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA. The abstract, “Oral Health Behaviors Associated with Mental Health Disorders” was presented during the ...

Researchers develop deep learning model to predict breast cancer

2024-03-19
OAK BROOK, Ill. – Researchers have developed a new, interpretable artificial intelligence (AI) model to predict 5-year breast cancer risk from mammograms, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA). One in 8 women, or approximately 13% of the female population in the U.S., will develop invasive breast cancer in their lifetime and 1 in 39 women (3%) will die from the disease, according to the American Cancer Society. Breast ...

Social activities can prevent cognitive decline in care facility residents

2024-03-19
Social activities such as interactions with others and participation in organised events can prevent cognitive decline in long-term care facility. Research from Amsterdam UMC, carried out among 3600 patients in 42 Dutch and Belgian care homes, shows that participation in social activities offers a protective effect for those with no, or little, cognitive impairment. These results are published today in the Journal of Alzheimer's Disease.   "Cognitive decline in long-term care residents is relatively common, a Canadian study showed that almost a quarter of residents cognitively declined after a year of residency," ...

BU study finds coping is related to longevity in older men

2024-03-19
(Boston)—Coping is defined as cognitive and behavioral efforts to manage stressors that people believe exceed their ability and resources to respond to effectively. While previous research has linked stressor characteristics, such as the type of event and its duration, and how stressed people feel in response to them, to higher mortality risk, far fewer studies have considered the long-term health consequences of how we manage stressors (coping) in large-scale studies.   In a new study from ...
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