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Cleveland Clinic study shows weight loss surgery cuts risk of heart complications and death in patients with obstructive sleep apnea and obesity

2024-06-21
Press release under embargo: Cleveland Clinic Study Shows Weight Loss Surgery Cuts Risk of Heart Complications and Death in Patients with Obstructive Sleep Apnea and Obesity  First-of-its-kind MOSAIC study shows weight-loss surgery is associated with a 42% reduction in risk of heart complications and 37% reduction in risk of death in patients with obstructive sleep apnea   Under embargo until Friday, June 21, 2024, 9:00 AM ET, CLEVELAND: A Cleveland Clinic study shows that bariatric surgery performed in patients with obesity and moderate to severe obstructive sleep apnea is associated with a significantly lower risk of ...

SQUID pries open AI black box

SQUID pries open AI black box
2024-06-21
Artificial intelligence continues to squirm its way into many aspects of our lives. But what about biology, the study of life itself? AI can sift through hundreds of thousands of genome data points to identify potential new therapeutic targets. While these genomic insights may appear helpful, scientists aren’t sure how today’s AI models come to their conclusions in the first place. Now, a new system named SQUID arrives on the scene armed to pry open AI’s black box of murky internal logic. SQUID, ...

Resiliency shaped by activity in the gut microbiome and brain

2024-06-21
A new UCLA Health study has found that resilient people exhibit neural activity in the brain regions associated with improved cognition and regulating of emotions, and were more mindful and better at describing their feelings. The same group also exhibited gut microbiome activity linked to a healthy gut, with reduced inflammation and gut barrier. For the study, rather than examine microbiome activity and composition linked to disease conditions-- like anxiety and depression -- the researchers wanted to flip the script and study the gut microbiome and brain in healthy, resilient people who effectively cope with different types of stress, including discrimination ...

Inspired by nature: synthetic nightshade molecule effective against leukemia cells

Inspired by nature: synthetic nightshade molecule effective against leukemia cells
2024-06-21
Nightshade plants produce a diverse array of compounds with therapeutic potential. Researchers at CeMM have now identified an artificial variant inspired by the Withanolides group that acts highly specifically against leukemia cells. Using state-of-the-art chemical and genetic high-throughput analyses, the team led by Georg Winter not only confirmed its effectiveness but also elucidated its mechanism of action: the molecule disrupts the cholesterol metabolism of tumor cells. The study's findings ...

Promise green hydrogen may not always be fulfilled

2024-06-21
Green hydrogen often, but certainly not always, leads to CO2 gains. This claim is based on research published in Nature Energy by Kiane de Kleijne from Radboud University and Eindhoven University of Technology. “If you calculate the entire life cycle of green hydrogen production and transport, CO2 gains may be disappointing. However, if green hydrogen is produced from very clean electricity and locally, it can really help reduce emissions.” It is thought that green hydrogen can make ...

Unifying behavioral analysis through animal foundation models

Unifying behavioral analysis through animal foundation models
2024-06-21
Although there is the saying, “straight from the horse’s mouth”, it's impossible to get a horse to tell you if it's in pain or experiencing joy. Yet, its body will express the answer in its movements. To a trained eye, pain will manifest as a change in gait, or in the case of joy, the facial expressions of the animal could change. But what if we can automate this with AI? And what about AI models for cows, dogs, cats, or even mice? Automating animal behavior not only removes observer bias, but it helps humans more efficiently get to the right answer. Today ...

Up to 30 percent more time: Climate change makes it harder for women to collect water

2024-06-21
Climate change could increase the amount of time women spend collecting water by up to 30 percent globally by 2050, according to a new study published in Nature Climate Change. In regions of South America and Southeast Asia, the time spent collecting water could double due to higher temperatures and less rainfall. A team of scientists from the Potsdam Institute for Climate Impact Research (PIK) estimates the large welfare losses that could result from climate impacts and highlights how women are particularly vulnerable to changing future climate conditions. Worldwide, two billion people currently lack access to safe drinking water. The ...

Heart failure in space: scientists calculate potential health threats facing future space tourists in microgravity

Heart failure in space: scientists calculate potential health threats facing future space tourists in microgravity
2024-06-21
[The following is a guest editorial written by Dr Lex van Loon, an assistant professor at the Australian National University and the University of Twente in the Netherlands. He is co-author of a new Frontiers in Physiology article.] Space exploration has always captivated our imagination, offering the promise of discovering new worlds and pushing the boundaries of human capability. As commercial space travel becomes more accessible, individuals with various underlying health conditions—including heart failure—may soon be among those venturing beyond Earth’s atmosphere. This raises critical questions about the impact of space travel ...

Experts offer guidance on talking with children about racism at pediatrician's office

2024-06-21
Extensive research shows the link between exposure to racism during childhood and adolescence and increased risks of depression and metabolic health issues, such as obesity, diabetes and heart disease. Conversely, racial socialization, described as behaviors and practices that teach children about race and ethnic identity, has shown potential in mitigating these negative effects, and discussions like these could be effective in pediatric clinics, according to the first expert consensus guidance on this topic published in Pediatrics. “Over the years, numerous calls to action have been made to address racism in medicine. ...

Drugs for HIV and AIDS trialed as brain tumor treatment for first time

Drugs for HIV and AIDS trialed as brain tumor treatment for first time
2024-06-21
Drugs developed to combat HIV and AIDS are being trialled for the first time in patients with multiple brain tumours. Scientists at the Brain Tumour Research Centre of Excellence at the University of Plymouth are conducting a clinical trial to see whether using anti-retroviral medications, Ritonavir and Lopinavir, could help people with Neurofibromatosis 2 (NF2). The rare inherited genetic condition causes tumours such as schwannoma (which include acoustic neuroma), ependymoma and meningioma which develop ...

Breakthrough in nanoscale force measurement opens doors to unprecedented biological insights

2024-06-21
Groundbreaking research has revealed a new way to measure incredibly minute forces at the nanoscale in water, pushing the boundaries of what scientists know about the microscopic world. The significant nanotechnology advance was achieved by researchers from Beihang University in China with RMIT University and other leading institutions including the Australian National University and University of Technology Sydney.  The new technique, involving a super-resolved photonic force microscope (SRPFM), is capable of detecting forces in water as small as 108.2 attonewtons—a scale so minute that it compares to measuring the weight of a virus. Lead ...

Scientists discover new behavior of membranes that could lead to unprecedented separations

Scientists discover new behavior of membranes that could lead to unprecedented separations
2024-06-21
Imagine a close basketball game that comes down to the final shot. The probability of the ball going through the hoop might be fairly low, but it would dramatically increase if the player were afforded the opportunity to shoot it over and over. A similar idea is at play in the scientific field of membrane separations, a key process central to industries that include everything from biotechnology to petrochemicals to water treatment to food and beverage. “Separations lie at the heart of so many of the products we use in our everyday lives,” said Seth Darling, head of the Advanced Materials for Energy Water Systems (AMEWS) Center at the U.S. Department of ...

When inflicting pain on others pays off T

When inflicting pain on others pays off T
2024-06-21
​ Oh, the joy of inflicting pain upon others. The Germans have a word for it: schadenfreude, meaning “malicious pleasure.” And tapping into its sentiment properly can, ironically, do a lot of good by raising money for charity. In a groundbreaking paper published in the Journal of Consumer Psychology, UC Riverside School of Business marketing professor and associate dean Thomas Kramer and co-authors articulate and quantify the appeal of schadenfreude (pronounced Sha-den-froid-e) through the lens of marketing psychology. Through a series of behavioral scenario studies, their paper provides insights ...

The Lancet: Managing gestational diabetes much earlier in pregnancy can prevent complications and improve long-term health outcomes, experts say

The Lancet: Managing gestational diabetes much earlier in pregnancy can prevent complications and improve long-term health outcomes, experts say
2024-06-21
The Lancet: Managing gestational diabetes much earlier in pregnancy can prevent complications and improve long-term health outcomes, experts say Speaking at the American Diabetes Association 84th Scientific Sessions, authors of a new Lancet Series challenge current approaches to managing gestational diabetes (a type of diabetes that can be diagnosed during pregnancy) and call for initiating treatment much earlier to prevent complications during pregnancy and beyond. [1].  Gestational Diabetes Mellitus (GDM), commonly referred to as gestational diabetes, is the most common ...

New study finds dinosaur fossils did not inspire the mythological griffin

New study finds dinosaur fossils did not inspire the mythological griffin
2024-06-21
A popular and widely-promoted claim that dinosaur fossils inspired the legend of the griffin, the mythological creature with a raptorial bird head and wings on a lion body, has been challenged in a new study. The specific link between dinosaur fossils and griffin mythology was proposed over 30 years ago in a series of papers and books written by folklorist Adrienne Mayor. These started with the 1989 Cryptozoology paper entitled ‘Paleocryptozoology: a call for collaboration between classicists and cryptozoologists’, and was cemented in the seminal 2000 ...

NASA astronaut Woody Hoburg to deliver keynote address at ISSRDC focused on developing a space workforce

NASA astronaut Woody Hoburg to deliver keynote address at ISSRDC focused on developing a space workforce
2024-06-20
BOSTON (MA), June 20, 2024 – NASA astronaut Warren “Woody” Hoburg will deliver a keynote address at the International Space Station Research and Development Conference (ISSRDC) in Boston on Thursday, August 1, 2024. Hoburg has close ties to Boston as a graduate and former assistant professor of aeronautics and astronautics at the Massachusetts Institute of Technology (MIT). Hoburg’s address will focus on his six-month science expedition on the space station and the importance of shaping the future workforce ...

Study: Fatigue-management training improved sleep, safety, well-being for Seattle police

2024-06-20
Policing is a profession that features shift work and long hours, both of which can lead to insufficient sleep and fatigue. Because of the unique demands of the job, fatigue raises risks related to decision making, impulse control, driving, and other aspects of work. In a new study, researchers tested the effect of a fatigue-management program on the sleep, mental health, well-being, and safety of police employees in Seattle. The training improved sleep duration as well as various aspects of employees’ safety and well-being. The study, by researchers at Washington State University (WSU) and the Seattle Police Department, ...

Guiding humanity beyond the moon: OHIO’s Nate Szewczyk and students coauthor papers published in “Nature” journals that revolutionize human space biology

2024-06-20
What actually happens to the human body in space? While scientists and researchers have heavily researched how various factors impact the human body here on Earth, the amount of information available about changes that occur in the body in space is not as well-known. Scientists, including OHIO’s Nate Szewczyk and several of his trainees, have been studying for years how the body, specifically on the molecular side, changes in space. Recently, a new package of papers has been published in “Nature” journals depicting how the modern tools of molecular biology and precision medicine can help guide humanity into more challenging missions beyond where we’ve already been. The ...

Grant supports research to identify barriers to health care for Black women

Grant supports research to identify barriers to health care for Black women
2024-06-20
A $1.58 million grant will support work by a health communication scholar at the University of Tennessee (UT) Health Science Center’s College of Nursing and a medical oncologist at West Cancer Center and Research Institute (WCCRI) to identify sociocultural and structural factors that are root causes of cancer health disparities for Black women in the Mid-South. Assistant Professor Janeane Anderson, PhD, MPH, is a social scientist and health communication scholar at the College of Nursing whose research focuses on how interpersonal factors affect ...

Scientists at uOttawa develop innovative method to validate quantum photonics circuits performance

Scientists at uOttawa develop innovative method to validate quantum photonics circuits performance
2024-06-20
A team of researchers from the University of Ottawa’s Nexus for Quantum Technologies Institute (NexQT), led by Dr. Francesco Di Colandreanorth_eastexternal link, under the supervision of Professor Ebrahim Karimi, associate professor of physics, has developed an innovative technique for evaluating the performance of quantum circuits. This significant advancement, recently published in the prestigious journal npj Quantum Information, represents a substantial leap forward in the field of quantum computing. In the rapidly evolving landscape of quantum technologies, ...

New report on community-centered approach to providing vaccine education and resources to persons experiencing homelessness during COVID-19

2024-06-20
(Boston)— A community-support model for providing health resources and education is a way to continuously engage unhoused people and other underserved groups who are particularly vulnerable during health emergencies like the COVID-19 pandemic. “Having a stable system for bringing health information to unhoused people and connecting them to providers at Boston Health Care for the Homeless Program (BHCHP), is a pathway for addressing a number of health issues they experience,” said Kareem King, Jr., research program manager at Boston University’s Clinical & Translational Science ...

Government updates race and ethnicity data collection standards: implications and insights

Government updates race and ethnicity data collection standards: implications and insights
2024-06-20
New Rochelle, NY, June 20, 2024–The latest issue of the peer-reviewed journal Health Equity features a pivotal roundtable discussion titled “Implications and Insights on Federal Revisions to Race and Ethnicity Collection.” This roundtable assembles leading experts to explore newly revised race and ethnicity data collection standards from the Office of Management and Budget (OMB), highlighting the significant impact these changes have on policy and practice. The expanded standards now capture historically marginalized communities, ...

Dr. Vivek S. Kavadi named CEO of the American Society for Radiation Oncology (ASTRO)

2024-06-20
ARLINGTON, Va., June 20, 2024 — The American Society for Radiation Oncology (ASTRO) announced today that following a nationwide search, Vivek S. Kavadi, MD, MBA, FASTRO will become CEO of the Society effective November 1, 2024. Dr. Kavadi will succeed Laura Thevenot, who previously announced her intent to retire after leading the organization since 2002. Dr. Kavadi, a radiation oncologist and ASTRO member since 1994, ascends to the role from his current position as Chief Radiation Oncology Officer for The ...

Dietary sucrose determines activity of lithium on gene expression and lifespan in drosophila melanogaster

Dietary sucrose determines activity of lithium on gene expression and lifespan in drosophila melanogaster
2024-06-20
  “[...] we found that, in female D. melanogaster, the life-prolonging effect of dietary lithium is dependent on the actual sucrose content of the medium.” BUFFALO, NY- June 19, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, “Dietary sucrose determines the regulatory activity of lithium on gene expression and lifespan in Drosophila melanogaster.” The amount of dietary sugars and the administration of lithium both impact the lifespan of the fruit fly Drosophila melanogaster. It is noteworthy that lithium ...

Assessment of CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management

Assessment of CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management
2024-06-20
“[...] these inexpensive, widely available tests with rapid turnaround times and relatively short half-lives (CEA, CA-125, and CA19-9) are perfectly situated to serve as adjunctive clinical tools in the management of NSCLC.” BUFFALO, NY- June 20, 2024 – A new research paper was published in Oncotarget's Volume 15 on June 13, 2024, entitled, “Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management.” Conventional tumor markers may serve as adjuncts in non-small cell lung cancer ...
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