Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments. In a study published in the peer-reviewed journal Cell Stem Cell, investigators detail how they created “ALS on a chip” and the clues the specialized laboratory chip has already produced about nongenetic causes of the disease, also known as Lou Gehrig’s disease. The work builds ...

Teens who see social media posts showing cannabis or e-cigarettes, including from friends and influencers, are more likely to later start using those substances or to report using them in the past month, according to surveys done by researchers at the Keck School of Medicine of USC. Viewing such posts was linked to cannabis use, as well as dual use of cannabis and e-cigarettes (vapes). Dual use refers to youth who have used both cannabis and e-cigarettes at some point. The results were just published in JAMA Network Open. The findings come amid a decline in youth e-cigarette use, reported in 2024 by the U.S. Food ...

Even the smartest machines can’t match young minds at language learning. Researchers share new findings on how children stay ahead of AI - and why it matters. If a human learned language at the same rate as ChatGPT, it would take them 92,000 years. While machines can crunch massive datasets at lightning speed, when it comes to acquiring natural language, children leave artificial intelligence in the dust. A newly published framework in Trends in Cognitive Sciences by Professor Caroline Rowland of the Max Planck Institute for Psycholinguistics, in collaboration with colleagues at the ESRC LuCiD Centre in the UK, presents a novel framework to explain how children ...

Tokyo, Japan – Mimicking the incredible skill of mother nature is never easy, especially when trying to match the remarkable chemical processes that take place in living organisms. Living systems, like cells, can carry out chemical reactions in very small spaces, sometimes involving single molecules. For many years, researchers have attempted to emulate this to allow for the manufacturing of specialized chemical compounds, but with limited success. However, new research published in the Journal of the American Chemical Society highlights the development of a new tool that assists with controlling chemical reactions. ...

A pretreatment step could help transplanted pancreatic islets survive longer in patients with type 1 diabetes, according to a new preclinical study from Weill Cornell Medicine investigators. One combination of small molecules extended the cells’ lives in female mice, and adding two molecules to the mixture boosted cell survival in male mice. The findings, published on June 24 in Cell Stem Cell, could allow physicians to treat more patients with fewer cells. In type 1 diabetes, autoimmune cells attack the pancreatic islets, destroying ...

Going off to summer camp can be a scary experience for children, but it can be even more nerve-wracking for parents of kids with food allergies. New UVA Health research reveals the most cost-effective way to keep those children safe. For most summer camps, stocking a supply of epinephrine – a common treatment for allergic reactions – rather than leaving it up to campers to bring their own is a safe strategy with the lowest overall cost for everyone involved, the UVA researchers found.  “Stock, unassigned ...

Key Takeaways Researchers led by Penn Integrates Knowledge Professor in the School of Arts & Sciences and the Perelman School of Medicine Shelley Berger explore the genetic basis of how communal-dwelling organisms like leafcutter ants and naked mole-rats divide labor among their societies They discovered that pathways dating back hundreds of millions of years are conserved across animal kingdoms Their findings offer fundamental insights into the origins of complex social behaviors and the neuroplasticity of assigned roles From the bright lights of cities that don’t ...

Journal: Injury Title: Pediatric Ice Hockey Injury Trends Presenting to U.S. Emergency Departments: A 10-Year Review of National Injury Data Authors: Luca M. Valdivia, MS, MD Candidate at the Icahn School of Medicine at Mount Sinai Sheena Ranade, MD, Associate Professor of Orthopedics, and Pediatrics, at the Icahn School of Medicine at Mount Sinai Bottom line: This study analyzes pediatric ice hockey injuries in emergency departments throughout the United States, finding a post-pandemic rise in head and shoulder injuries as well as hospitalizations. Why this study is unique: This ...

On April 29th, the Vaccine Innovation Center (Director Chung Hee-Jin) of Korea University's College of Medicine successfully held a special seminar with Professor Pierre Van Damme, a world-renowned vaccine expert, at the Yoon Joo-Hong lecture room, 4th floor main building.   61 researchers joined this seminar to have in-depth discussions on the latest research trends and strategies in vaccine development and clinical trials.     Professor Pierre Van Damme is a world-renowned vaccine expert who has been selected as one of the 2025 recipient of the Park Man-Hoon Award for his contribution to lead the development of the first oral polio ...

Multilayer ceramic capacitors (MLCCs) (1), which utilize ferroelectric ceramics, are widely used as electronic components in various devices such as smartphones, personal computers, televisions, and automotive systems. With the advancement of mobile devices, home appliances, and IoT technologies, there is an increasing demand for MLCCs to become more compact, offer higher capacitance, and exhibit greater reliability. MLCCs are structured with alternating layers of ferroelectric material and internal electrodes. Within the ferroelectric layers, there are domains with differing polarization directions, as well as domain interfaces on the nanometer (one-billionth of a ...

Researchers have unveiled a simple yet effective satellite-based tool to track Spartina alterniflora, one of the most aggressive invasive plant species threatening coastal wetlands. Using freely accessible Sentinel-2 imagery, the new Spartina alterniflora Index (SAI) enables precise, large-scale mapping of this fast-spreading species. Outperforming traditional vegetation indices and rivaling machine learning models in accuracy, SAI offers a scalable and practical solution for environmental monitoring and wetland protection. Originally introduced to China in the 1970s to control erosion and support land ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, determines which genetic instructions are activated. When this fails, the wrong parts of the genome can be activated, leading to cancers and neurodevelopmental disorders. Scientists at the University of Geneva (UNIGE) have identified two proteins that play a key role in regulating this essential mechanism, paving the way for promising new treatments that could be more effective and less toxic than those currently available. Their findings are published in Nature Communications. Human DNA contains over 20,000 genes and would stretch nearly two metres ...

For decades, researchers have pursued lead-free alternatives to replace toxic yet high-performance lead-based antiferroelectrics (AFEs). Sodium niobate (NaNbO3, NN) emerged as a prime candidate due to its low cost and environmentally benign nature. However, its irreversible phase transition at room temperature, resulting in energy-wasting ferroelectric-like hysteresis, has hindered practical applications. The team published their work in Journal of Advanced Ceramics on June 18, 2025. Now, a materials scientists team has cracked this challenge through ions co-doping strategic. As published in Journal of Advanced Ceramics, co-doping NN with variable-valence elements Sn and Ce ...

A multinational team of researchers, co-led by the Garvan Institute of Medical Research, has developed and tested a new AI tool to better characterise the diversity of individual cells within tumours, opening doors for more targeted therapies for patients. Findings on the development and use of the AI tool, called AAnet, have today been published in Cancer Discovery, a journal of the American Association for Cancer Research. Not all tumour cells the same Tumours aren't made up of just one cell type – they're a mix of different cells that grow and ...

Miami (June 24, 2025) – Prevalence of chronic obstructive pulmonary disease (COPD) and the disease’s burden varies significantly by state. Understanding this variation could help address public health gaps to ease the burden on people with COPD and the health care system, according to a new study. The study is published in the March 2025 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal. COPD is an inflammatory lung disease, comprising several conditions, including chronic bronchitis and emphysema, and can ...

For the first time in the world, a Korean research team discovered how cellular aging can spread systemically through the bloodstream—offering new insights and a potential therapeutic strategy to combat aging-related decline.   Professor Ok Hee Jeon's research group at the Department of Convergence Medicine, Korea University's College of Medicine, discovered that High Mobility Group Box 1 (HMGB1),a key extracellular senescence-associated secretory phenotype (SASP) factor, plays a ...

The official results of the BRACELET-01 (PrECOG 0113) trial have been published in Clinical Cancer Research, detailing the safety and efficacy of pelareorep, an investigational oncolytic virus immunotherapy, when added to paclitaxel chemotherapy, both with and without the checkpoint inhibitor avelumab. The trial included 48 patients with unresectable metastatic hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) tumors. All had experienced disease progression after receiving at least ...

PLYMOUTH MEETING, PA [June 24, 2024] — The National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers—announces a new, interactive digital delivery format for the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®).  The NCCN Guidelines® are the recognized standard for clinical decision making and policy in cancer care and are the most thorough and frequently updated clinical practice guidelines available in any area of medicine. They assist in the decision-making process of individuals involved in cancer care and prevention—including ...

On the younger, black-rock islands of the Galápagos archipelago, wild-growing tomatoes are doing something peculiar. They’re shedding millions of years of evolution, reverting to a more primitive genetic state that resurrects ancient chemical defenses. These tomatoes, which descended from South American ancestors likely brought over by birds, have quietly started making a toxic molecular cocktail that hasn’t been seen in millions of years, one that resembles compounds found in eggplant, not the modern tomato. In a study published recently in Nature Communications, scientists at the University ...

Conservation, restoration, and ecosystem management can reduce greenhouse gas emissions or increase carbon dioxide sequestration, in what frequently are referred to as “natural climate solutions.” Such natural climate solutions have  gained global attention in recent years as they could provide over one-third of the climate mitigation required to keep global warming under 2°C (3.6°F) by 2030. The authors mapped social, political, informational, and economic roadblocks that prevent implementation of natural climate solutions around the world, drawing ...

Is excessive wealth immoral? Most people do not think so, but members of societies that are more equal and wealthy than average are more likely to believe it is wrong to have too much money.  Currently, the world’s eight richest individuals have as much wealth as the bottom 50% of people worldwide. There are two distinct moral objections to such extreme wealth. One is that economic inequality is wrong, an opinion shared by a majority of people worldwide. The other is that extreme wealth itself is wrong. Jackson Trager and Mohammad Atari recruited survey samples mirroring demographics in terms of gender, education, and age for 20 nations, totaling 4,351 participants overall. Participants ...

Predicting cognitive abilities from brain imaging has long been a central goal in cognitive neuroscience. While machine learning has modestly improved predictions using brain MRI data, most studies rely on a single MRI modality. Narun Pat and colleagues integrated multiple MRI modalities through a technique called stacking. The method combines structural MRI (e.g., cortical thickness), resting-state and task-based functional connectivity, and task-evoked blood-oxygen-level-dependent (BOLD) contrasts to build a more robust neural marker of cognitive function. The authors analyzed data from 2,131 participants aged 22 to 100 from three ...

Overall, 46% of adults age 65 and older have taken steps to “age in place,” according to a new poll. This includes 31% who have made modifications to make their home more age-friendly and 26% who have already moved to a place that can meet their needs as they age. Some older adults have done both.  That’s even though most older adults polled – 84% – said it’s very or somewhat likely that they’ll live in their current home for the rest of their life. This includes 80% of those who have not yet taken any steps to age in place.  The new findings from the National Poll on ...

Bright colors, fruit imagery, and labels like “locally made” or “vegan” might seem harmless—but when used on cannabis edibles, they can send misleading messages to teens. That’s according to a new Washington State University-led study examining how adolescents perceive the packaging of cannabis-infused products such as gummies, chocolates and sodas. Despite regulations barring packaging that targets youth, many teens in the study found these products appealing— often likening them to everyday ...

People often delay returning to lost pleasures, according to a study. When people are unable to engage in enjoyable activities, from catching up with friends to going to the movies, one might think that they would jump at the chance to return. However, Linda Hagen and Ed O’Brien show in a series of surveys and experiments that people often delay returning to previously rewarding behaviors. After the end of COVID-19 shutdowns, surveyed Americans reported waiting additional time to return to restaurants, movie theaters, parties, vacations, and family visits so that their return would be especially ...