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The consequences of late preterm birth

2012-11-12
Delivery at any time before the 39th week of gestation increases the risk of postnatal problems and mortality. A team of authors headed by Christian F. Poets has analyzed mortality and morbidity data from epidemiological studies of infants born between two and six weeks preterm, comparing them with infants born at full term. They present their findings in issue 43 of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2012; 109(43): 721−6). As a rule, elective Cesarean sections are performed somewhat before full term, in order to prevent spontaneous delivery. However, ...

Ultrasound gel and infections: Researchers propose guidelines to reduce risk

2012-11-12
CHICAGO (November 12, 2012) – In the December issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America, guidelines have been proposed by epidemiologists from Beaumont Health System to reduce the risk of infection from contaminated gels. The recommendations are based on the authors' own experiences with an outbreak traced to contaminated ultrasound transmission gel. In December 2011, researchers uncovered an unusual cluster of Pseudomonas aeruginosa in a cardiovascular surgery intensive care unit during routine ...

Study justifies L-DOPA therapy for Angelman syndrome

Study justifies L-DOPA therapy for Angelman syndrome
2012-11-12
CHAPEL HILL, N.C. – Last year a clinical trial of L-DOPA -- a mainstay of Parkinson's disease therapy -- was launched for Angelman syndrome, a rare intellectual disorder that shares similar motor symptoms such as tremors and difficulty with balance. The clinical trial is based on a 10-year-old case report showing benefit with the drug, but few studies since have explored the neurological justification for using L-DOPA to treat parkinsonian features in Angelman syndrome. New research from the University of North Carolina School of Medicine, conducted in animal models ...

Patients shy away from asking healthcare workers to wash hands

2012-11-12
CHICAGO (November 12, 2012) – According to a new study published online today, most patients at risk for healthcare-associated infections (HAIs) agree that healthcare workers should be reminded to wash their hands, but little more than half would feel comfortable asking their physicians to wash. The study is published in the December issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. The study points to the need for patient empowerment to improve hand hygiene of healthcare workers. Researchers from ...

PI3-kinase and PARP inhibitor combo may offer new treatment option for triple-neg breast cancers

2012-11-12
PHILADELPHIA — The simultaneous inhibition of two separate and seemingly unrelated pathways could potentially provide an effective treatment for women with triple-negative breast cancer, according to results of two studies published in the November issue of Cancer Discovery, a journal of the American Association for Cancer Research. Triple-negative breast cancers do not express three common targets of breast cancer treatments: the estrogen receptor, progesterone receptor and HER2/neu. As a result, women with triple-negative breast cancer have few treatment options. In ...

UNC, Vanderbilt discover a new live vaccine approach for SARS and novel coronaviruses

2012-11-12
Rapid mutation has long been considered a key to viral adaptation to environmental change. But in the case of the coronavirus responsible for deadly severe acute respiratory syndrome (SARS), collaborating researchers at the University of North Carolina and Vanderbilt University have found that accelerating the rate of mutations cripples the virus's ability to cause disease in animals. In addition, they say this finding may allow scientists to explore a new option for creating safer live vaccines. A collaborative study, published Nov. 11 in Nature Medicine, demonstrates ...

Bringing measuring accuracy to radical treatment

2012-11-12
An international team of scientists working at the Plasma Technology research unit at Ghent University, Belgium, has determined for the first time the absolute density of active substances called radicals found in a state of matter known as plasma, in a study about to be published in EPJ D. These findings could have important implications for medicine—for example, for stimulating tissue regeneration, or to induce a targeted antiseptic effect in vivo without affecting neighbouring tissues. Qing Xiong and colleagues utilised laser fluorescence spectroscopy (LIF), a detection ...

Duke Medicine news -- Genome sequencing of Burkitt Lymphoma reveals unique mutation

2012-11-12
DURHAM, N.C. – In the first broad genetic landscape mapped of a Burkitt lymphoma tumor, scientists at Duke Medicine and their collaborators identified 70 mutations, including several that had not previously been associated with cancer and a new one that was unique to the disease. Findings from the genetic sequencing of Burkitt lymphoma, an aggressive form of lymphoma, could be used to develop new drugs or aim existing therapies at mutations known to be susceptible. The researchers published their findings online Sunday, Nov. 11, 2012, in the journal Nature Genetics. "This ...

News from Annals of Internal Medicine

2012-11-12
Philadelphia, November 12, 2012 – A new article being published early online in Annals of Internal Medicine describes the diagnosis and treatment protocol established in a Roanoke, Va. hospital to care for dozens of patients presenting with suspected fungal meningitis related to contaminated epidural spinal injections. This unprecedented surge of patients seeking care for a rare central nervous system (CNS) infection required physicians to react quickly with little data to guide treatment decisions. The authors suggest that the data collected from these cases may fill information ...

Genetic link between pancreatitis and alcohol consumption, says Pitt team

2012-11-12
PITTSBURGH, Nov. 12, 2012 – A new study published online today in Nature Genetics reveals a genetic link between chronic pancreatitis and alcohol consumption. Researchers from the University of Pittsburgh School of Medicine and more than 25 other health centers across the United States found a genetic variant on chromosome X near the claudin-2 gene (CLDN2) that predicts which men who are heavy drinkers are at high risk of developing chronic pancreatitis. This finding enables doctors to identify people with early signs of pancreatitis or an attack of acute pancreatitis ...

Job stress and mental health problems contribute to higher rates of physician suicide

2012-11-12
ANN ARBOR, Mich. — Doctors who commit suicide appear to be under-treated for mental health problems, despite their seemingly good access to health care, a new University of Michigan study shows. Although more physicians than non-physicians in the study had known mental health problems prior to suicide, this didn't translate into a higher rate of antidepressant use, according to the study, which appears in General Hospital Psychiatry and provides a deeper look at why physicians may have a higher-than-average suicide rate. Major depression is a known risk factor for ...

Robots enable scar-free hysterectomies for some women

Robots enable scar-free hysterectomies for some women
2012-11-12
AUGUSTA, Ga. – The precision and three-dimensional view provided by robots can enable essentially scar-free surgery for some women needing hysterectomies, physicians report. The case report in the Journal of Minimal Access Surgery is of a 46-year-old physically fit female with a history of excessive bleeding and benign growths on her uterus. Her surgery was performed through a two inch-long incision in the belly button, the thinnest part of the abdomen, using the robotic arms in a "chopstick" fashion, said Dr. John R. Lue, Chief of the Medical College of Georgia Section ...

Desecrated ancient temple sheds light on early power struggles at Tel Beth-Shemesh

2012-11-12
Tel Aviv University researchers have uncovered a unique 11th century BCE sacred compound at the site of Tel Beth-Shemesh, an ancient village that resisted the aggressive expansion of neighboring Philistines. The newly discovered sacred complex is comprised of an elevated, massive circular stone structure and an intricately constructed building characterized by a row of three flat, large round stones. Co-directors of the dig Prof. Shlomo Bunimovitz and Dr. Zvi Lederman of TAU's Sonia and Marco Nadler Institute of Archaeology say that this temple complex is unparalleled, ...

FASEB urges biomedical research community to speak out against sequestration

2012-11-12
Bethesda, MD – The Federation of American Societies for Experimental Biology (FASEB) is rallying the biomedical research community to advocate against devastating funding cuts facing the nation's research agencies unless Congress acts before the end of the year. Under sequestration, the National Institutes of Health (NIH) could lose $2.8 billion and would fund 25 percent (2,300) fewer grants. The National Science Foundation (NSF) could be cut by nearly $600 million. More than 5,800 emails have been sent to Congress in response to a FASEB e-action alert urging individuals ...

National study shows protective eyewear reduces eye, head, and facial injuries

2012-11-12
PROVIDENCE, R.I. – A new study conducted by researchers at Hasbro Children's Hospital, the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital, Fairfax (VA) County Public Schools, and Boston Children's Hospital has found that high school field hockey players competing in states with mandated protective eyewear have significantly lower rates of head, eye, and facial injuries when compared to players who compete in states without protective eyewear mandates. Each academic year, an estimated 63,000 girls participate in high ...

New cause of thyroid hormone deficiency discovered

2012-11-12
International researchers, including a team at McGill University, have discovered a new cause for thyroid hormone deficiency, or hypothyroidism. This common endocrine disorder is typically caused by problems of the thyroid gland, and more rarely, by defects in the brain or the pituitary gland (hypophysis). However, a new cause of the disease has been discovered from an unsuspected source and is reported in the journal Nature Genetics. The scientists, led by McGill Professor Daniel Bernard, Department of Pharmacology and Therapeutics in the Faculty of Medicine, identified ...

More scientific research of 'fracking' urged in Pennsylvania

2012-11-12
"Pennsylvania has opened up its doors to fracking in ways that many other states in the U.S. have not," said David Dausey, Ph.D., chair of the Mercyhurst University Public Health Department. "We don't know enough about the environmental and human health effects of fracking and, as a result, Pennsylvania has become the home of experimental fracking." Dausey discusses his concerns in this month's episode of The Dausey File: Public Health News Today. Hydraulic fracturing or fracking is a controversial method to extract natural gas or petroleum from subterranean shale ...

'Social environmental factors' affect rehospitalization risk in home healthcare patients

2012-11-12
Philadelphia, Pa. (November 12, 2012) – For elderly patients receiving home healthcare after a hospital stay, "social environmental factors"—particularly care provided by a family member or other informal caregiver—have a significant impact on the risk of repeated hospital admissions, reports a study in the October-December issue of Advances in Nursing Science. The journal is published by Lippincott Williams & Wilkins, a part ofWolters Kluwer Health. "Understanding how social environmental factors contribute to home healthcare patients being rehospitalized would be ...

'Raising the african voice' on climate change

2012-11-12
LAGOS, Nigeria – Fifteen science academies of Africa issued a joint statement in Lagos, Nigeria, today calling on the African scientific community to intensify its study of the impact of climate change. Noting that Africa's contribution of scientific information to understanding climate change has been "meagre" to date, the statement calls for African researchers to step up their observation, modeling, and analyses of the effects of climate change on a regional scale, and to help plan interventions to mitigate and adapt to the impacts of climate change on the continent. ...

Persistence or extinction: Through a mathematical lens

2012-11-12
Philadelphia, PA—Scientists have estimated that there are 1.7 million species of animals, plants and algae on earth, and new species continue to be discovered. Unfortunately, as new species are found, many are also disappearing, contributing to a net decrease in biodiversity. The more diversity there is in a population, the longer the ecosystem can sustain itself. Hence, biodiversity is key to ecosystem resilience. Disease, destruction of habitats, pollution, chemical and pesticide use, increased UV-B radiation, and even the presence of new species are some of the causes ...

Childhood obesity more likely to affect children in poorer neighborhoods

2012-11-12
Children living in poorer neighborhoods are nearly 30 percent more likely to be obese than children in more affluent residences, according to a new study from Rice University. The study by Rice sociologists Rachel Tolbert Kimbro, director of the Kinder Institute for Urban Research's Urban Health Program, and Justin Denney, associate director of the program, reveals that living in neighborhoods with higher levels of poverty and lower levels of education is associated with increased child obesity risk, regardless of family composition or other individual factors. The research ...

New low carbon TINA reports

2012-11-12
The role that new low carbon technologies can play in helping the UK meet its targets for reducing greenhouse gas emissions and moving towards a green economy have been highlighted today with the publication of three in-depth reports into core areas of innovation. These three new analyses, Technology Innovation Needs Assessments (TINAs), cover non-domestic buildings, industrial emissions efficiency, and domestic buildings and are part of a series that spans 11 low carbon technology areas. The TINAs examine the potential for innovation in these technologies and assess the ...

Babies rely on words to 'decode' underlying intentions of others

2012-11-12
EVANSTON, Ill. --- A new Northwestern University study shows the power of language in infants' ability to understand the intentions of others. As the babies watched intently, an experimenter produced an unusual behavior--she used her forehead to turn on a light. But how did babies interpret this behavior? Did they see it as an intentional act, as something worthy of imitating? Or did they see it as a fluke? To answer this question, the experimenter gave 14-month-old infants an opportunity to play with the light themselves. The results, based on two experiments, ...

Scientists take objective look at terms 'least toxic pesticides' applied as 'last resort'

2012-11-12
Recommendations and decisions to use "least toxic pesticides" and "pesticides as a last resort" have flourished in the last decade, but according to three scientific organizations – the Weed Science Society of America (WSSA), the American Phytopathological Society (APS) and the Plant-Insect Ecosystems Section of the Entomological Society of America (P-IE ESA) – these are not the correct approaches to the pesticide component of an Integrated Pest Management (IPM) program. The three organizations have joined to take an objective look at the problems associated with "least ...

Which U.S. Presidents Served in the Military? New Infographic from iFreedom Direct has the Answer

2012-11-12
iFreedom Direct, a dedicated VA-approved lender serving military members, celebrates Veterans Day 2012 by debuting an informative new graphic on its two company websites and Facebook page. The infographic entitled Beyond Commander in Chief features a timeline of the 44 Presidents and their terms along with 24 headshots of those who served their country in the Armed Forces before calling the White House their home. Of course, George Washington started it all when he was named Commander in Chief of the Continental Army in 1775 -- even before being elected President. ...
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