ITHACA, N.Y. – A bit reminiscent of the Terminator T-1000, a new material created by Cornell researchers is so soft that it can flow like a liquid and then, strangely, return to its original shape. Rather than liquid metal, it is a hydrogel, a mesh of organic molecules with many small empty spaces that can absorb water like a sponge. It qualifies as a "metamaterial" with properties not found in nature and may be the first organic metamaterial with mechanical meta-properties. Hydrogels have already been considered for use in drug delivery – the spaces can be filled with ...

Johns Hopkins researchers have used a small synthetic molecule to stimulate cells to move and change shape, bypassing the cells' usual way of sensing and responding to their environment. The experiment pioneers a new tool for studying cell movement, a phenomenon involved in everything from development to immunity to the spread of cancer. "We were able to use synthetic molecules small enough to slip inside the cell and activate a chemical reaction controlling cell movement, bypassing most of the steps that usually lead up to this reaction," says Andre Levchenko, Ph.D., ...

Bag-in-box wines are more likely than their bottled counterparts to develop unpleasant flavors, aromas and colors when stored at warm temperatures, a new study has found. Published in ACS' Journal of Agricultural and Food Chemistry, it emphasizes the importance of storing these popular, economical vintages at cool temperatures. Helene Hopfer and colleagues explain that compounds in wine react with oxygen in the air to change the way wine looks, tastes and smells. These reactions speed up with increasing temperature. Many winemakers are moving away from the traditional ...

Scientists have discovered a previously unrecognized way that degradation can occur in silicone-urethane plastics that are often considered for use in medical devices. Their study, published in ACS' journal Macromolecules, could have implications for device manufacturers considering use of these plastics in the design of some implantable devices, including cardiac defibrillation leads. Kimberly Chaffin, Marc Hillmyer, Frank Bates and colleagues explain that some implanted biomedical devices, such as pacemakers and defibrillators, have parts made of a plastic consisting ...

Chicago (December 5, 2012): As the nation grapples with surging health care costs, researchers at the University of Connecticut Health Center, Farmington, and Saint Francis Hospital and Medical Center, Hartford, have confirmed two simple cost-effective methods to reduce expensive postoperative complications—communications team training and a surgical checklist. Investigators found that when surgical teams completed communications training and a surgical procedure checklist before, during, and after high-risk operations, patients experienced fewer adverse events such as ...

In a discovery with applications ranging from hair dyeing to electronic sensors to development of materials with improved properties, scientists are reporting the first synthesis of gold nanoparticles inside human hairs. Their study appears in ACS' journal Nano Letters. Philippe Walter and colleagues explain that gold nanoparticles — 40,000-60,000 of which could fit across the width of a human hair — are a hot topic. Scientists are exploring uses, ranging from electronics and sensors to medical diagnostic tests and cancer treatments. Gold nanoparticles have been deposited ...

A new web-based resource on climate science, designed to help scientists and others understand this key topic, is the focus of a Comment article in the current edition of Chemical & Engineering News (C&EN), the American Chemical Society's weekly newsmagazine. ACS, the world's largest scientific society, launched the resource this week. ACS President Bassam Z. Shakhashiri explains in the article that the Society is among the major scientific organizations with position statements acknowledging the reality of climate change and recommending action. ACS' policy statement ...

AUDIO: This audio file reports findings that African American women are less likely to receive improved surgical procedure for breast cancer. Click here for more information. San Antonio - African American women with early stage, invasive breast cancer were 12 percent less likely than Caucasian women with the same diagnosis to receive a minimally invasive technique, axillary sentinel lymph node (SLN) biopsy, years after the procedure had become the standard of surgical practice, ...

It's the least understood organ in the human body: the brain, a massive network of electrically excitable neurons, all communicating with one another via receptors on their tree-like dendrites. Somehow these cells work together to enable great feats of human learning and memory. But how? Researchers know dendritic spines play a vital role. These tiny membranous structures protrude from dendrites' branches; spread across the entire dendritic tree, the spines on one neuron collect signals from an average of 1,000 others. But more than a century after they were discovered, ...

WASHINGTON — Without a national consensus on strategic goals and objectives for NASA, the agency cannot be expected to establish or work toward achieving long-term priorities, says a new report from the National Research Council. In addition, there is a mismatch between the portfolio of programs and activities assigned to the agency and the budget allocated by Congress, and legislative restrictions inhibit NASA from more efficiently managing its personnel and infrastructure. The White House should take the lead in forging a new consensus on NASA's future in order to more ...

RICHMOND, Va. (Dec. 5, 2012) – Approximately 68 percent of U.S. adults are overweight or obese, according to the National Cancer Institute, which puts them at greater risk for developing cancer, cardiovascular disease, diabetes and a host of other chronic illnesses. But an international team of scientists led by Virginia Commonwealth University Massey Cancer Center researcher Andrew Larner, M.D., Ph.D., has successfully reversed obesity in mice by manipulating the production of an enzyme known as tyrosine-protein kinase-2 (Tyk2). In their experiments, the scientists discovered ...

An international team of researchers looked at the role of personality by studying 298 gorillas in North American zoos and sanctuaries for over 18 years. The gorillas' personalities were assessed by keepers, volunteers, researchers and caretakers who knew the gorillas well. Their personality was scored with measures adapted from techniques for studying people and other primates. Researchers found that out of four personality traits – dominance, extraversion, neuroticism and agreeableness – extraversion, which was associated with behaviours such as sociability, activity, ...

SANTA CRUZ, CA--An ongoing investigation of elevated mercury levels in coastal fog in California suggests that upwelling of deep ocean water along the coast brings mercury to the surface, where it enters the atmosphere and is absorbed by fog. Peter Weiss-Penzias, an environmental toxicologist at the University of California, Santa Cruz, who leads the investigation, emphasized that the amount of mercury in fog is not a health concern. "These are parts-per-trillion levels, so when we say elevated, that's relative to what was expected in atmospheric water," he said. "The ...

Colin P. West, M.D., Ph.D., and Denise M. Dupras, M.D., Ph.D., of Mayo Clinic, Rochester, Minn., conducted a study to evaluate career plans of internal medicine residents. "General internists provide comprehensive and coordinated care for both acute and chronic diseases. General internists are expected to play an increasingly critical role in health care provision as the population ages, the burden of chronic disease grows, and health care reform targets coverage of tens of millions of currently uninsured patients," according to background information in the article. ...

Kevin G. Volpp, M.D., Ph.D., of the Philadelphia Veterans Affairs Medical Center and University of Pennsylvania, Philadelphia, and colleagues conducted a study to determine whether a protected sleep period of 5 hours is feasible and effective in increasing the time slept by interns on extended duty overnight shifts. In 2009, the Institute of Medicine (IOM) published a report on resident work hours and work schedules to improve patient safety that recommended a protected sleep period of 5 hours during any work shift longer than 16 hours to reduce the risk of fatigue-related ...

Peter Yeates, M.B.B.S., M.Clin.Ed., of the University of Manchester, United Kingdom, and colleagues conducted a study to examine whether observations of the performance of postgraduate year 1 physicians influence raters' scores of subsequent performances. "The usefulness of performance assessments within medical education is limited by high interrater score variability, which neither rater training nor changes in scale format have successfully ameliorated. Several factors may explain raters' score variability, including a tendency of raters to make assessments by comparing ...

Brian P. Lucas, M.D., M.S., of the Cook County Health and Hospitals System and Rush Medical College, Chicago, and colleagues conducted a study to compare the effects of 2- vs. 4-week inpatient attending physician rotations on unplanned patient revisits (a measure to assess the effect on patients), attending evaluations by trainees, and attending propensity for burnout. "Trainees learn inpatient medicine on the job, providing clinical care to patients as members of ward teams led by attending physicians. Although the structures of these ward teams vary by local educational ...

Kevin W. Eva, Ph.D., of the University of British Columbia, Vancouver, and colleagues conducted a study to determine whether students deemed acceptable through a revised admissions protocol using a 12-station multiple mini-interview (MMI) would outperform rejected medical students when they later took the Canadian national licensing examinations after completing medical school. The MMI process requires candidates to rotate through brief sequential interviews with structured tasks and independent assessment within each interview. "Modern conceptions of medical practice ...

Children with implanted heart-rhythm devices and their parents suffer from a lower quality of life compared with their healthy counterparts and may benefit from psychotherapy according to new research in Circulation: Arrhythmia & Electrophysiology, an American Heart Association journal. Researchers at the Cincinnati Children's Hospital Medical Center studied 173 children with either a pacemaker (40 patients) or implanted defibrillator (133 patients) to assess their quality of life compared to other children with congenital heart disease and to healthy children. The children, ...

HOUSTON – (Dec. 4, 2012) –The ability of the eye of a fruit fly (Drosophila melanogaster) to respond to light depends on a delicate ballet that keeps the supply of light sensors called rhodopsin constant as photoreceptors turn on and off in response to light exposures, said researchers from Baylor College of Medicine (www.bcm.edu) and the Jan and Dan Duncan Neurological Research Institute (http://www.nri.texaschildrens.org/) at Texas Children's Hospital in an article that appears online in the journal PLOS Biology (http://www.plosbiology.org/home.action). The gene Crag ...

Training human volunteers to control their own brain activity in precise areas of the brain can enhance fundamental aspects of their visual sensitivity, according to a new study. This non-invasive 'neurofeedback' approach could one day be used to improve brain function in patients with abnormal patterns of activity, for example stroke patients. Researchers at the Wellcome Trust Centre for Neuroimaging at UCL used non-invasive, real-time brain imaging that enabled participants to watch their own brain activity on a screen, a technique known as neurofeedback. During the ...

New research shows that the concentration of sperm in men's semen has been in steady decline between 1989 and 2005 in France. In addition, there has been a decrease in the number of normally formed sperm. The study is published online today (Wednesday) in Europe's leading reproductive medicine journal Human Reproduction [1]. The study is important because, with over 26,600 men involved, it is probably the largest studied sample in the world and although the results cannot be extrapolated to other countries, it does support other studies from elsewhere that show similar ...

Poor women who drank tea were viewed as irresponsible as whisky drinkers in early 19th-century Ireland, new research by Durham University has unearthed. Critics at the time declared that the practice of tea drinking – viewed as a harmless pastime in most past and present societies – was contributing to the stifling of Ireland's economic growth, and was clearly presented as reckless and uncontrollable. Women who drank tea wasted their time and money, it was said, drawing them away from their duty to care for their husbands and home. It was felt this traditionally female ...

Research published on bmj.com today suggests that although more babies survived shortly after extreme preterm birth in England in 2006 compared with 1995, the number with major conditions on leaving hospital remained largely unchanged. A second study, also published today, shows some improvement in the number of extremely preterm children who survived without disability at 3 years of age, but no change in the rate of serious health and developmental problems over the same 10-year period. Taken together, these two large studies (known as the EPICure studies) suggest ...

Health inequalities between England's richest and poorest areas have widened in the ten years between 1999 and 2008. Researchers warn, in a study published today on bmj.com, that over the next ten years, we may experience smaller increases in life expectancy than in the past decade and health inequalities may rise at an even faster rate. Studies have shown that economic decline is associated with long term negative health impacts and the current climate has raised concerns about this. Between 1999 and 2008 the target (set by the government) for reducing the gap in life ...