Endoscopic studies presented at Digestive Disease Week
2024-05-20
Washington (May 14, 2024) — Studies featuring endoscopic and laparoscopic procedures, including patient views on artificial intelligence in endoscopy and hazards to healthcare personnel of smoke-producing procedures, will be presented this week at Digestive Disease Week (DDW) 2024. Abstracts are available to registered media, and press releases are available where noted. Research is embargoed until 12:01 a.m. EDT the day of presentation, unless otherwise noted.
Here are summaries of the new research:
Patients’ sentiments ...
Hunger hormone, antibiotic-induced weight gain, and sleep and digestive health explored at Digestive Disease Week
2024-05-20
Washington (May 14, 2024) — Studies exploring the hunger hormone, weight-loss drugs, sauerkraut and antibiotic weight gain, the impact of physician gender on care, and the relationship between sleep patterns and digestive diseases will be presented this week at Digestive Disease Week (DDW) 2024. Abstracts are available to registered media. Embargos lift at 12:01 a.m. EDT on the day they are presented unless otherwise noted.
Here are summaries of the new research:
Performance of a machine-learning gene ...
Innovative 3D printing could revolutionise treatment for cataracts and other eye conditions
2024-05-20
Peer-reviewed – Proof-of-concept study
University of East Anglia researchers have made a significant breakthrough in ocular device technology with the introduction of a novel resin for 3D printing intraocular devices. This innovation has potential to enhance the manufacture of eye implants universally used in cataract and refractive surgeries.
An artificial intraocular lens (IOL) is primarily required for people with cataracts, a condition where the eye’s natural lens becomes cloudy, obscuring vision.
They can also be also used to correct refractive errors such as myopia (nearsightedness), ...
Rigid approach to teaching phonics is ‘joyless’ and is failing children, experts warn
2024-05-20
Experts have released robust research to show that phonics should be taught hand-in-hand with reading and writing to encourage true literacy and a love of reading, not through narrow synthetic phonics.
There is widespread disagreement globally across academic and educational spheres about the best way to teach children to learn to read and write. Despite a growing international trend towards a narrow approach to synthetic phonics, experts suggest there is a ‘better way’ to teach reading and writing.
In England, the system is among the most prescriptive in the world with ‘synthetic phonics’ being the ...
Meerkat chit-chat
2024-05-20
EMBARGOED UNTIL MONDAY, 20 MAY 2024, 01:01 CEST (00:01 BST/London Time)
Meerkats use two different types of vocal interactions to stay in touch with their group mates. Sometimes the call simply broadcasts information, whereas other times meerkats engage in a call exchange with their neighbours, as researchers from the Centre for the Advanced Study of Collective Behaviour at the University of Konstanz and the Max Planck Institute of Animal Behavior present in a new publication published on 20 May in Philosophical Transactions of the Royal Society B.
What does it sound like ...
Extreme heat associated with children’s asthma hospital visits
2024-05-20
EMBARGOED UNTIL: 2:15 p.m. PT, May 19, 2024
Session: A95 – Climate Change and Health Disparities in Lung Disease
Extreme Heat and Asthma Hospitalizations in Children in California (2017-2020)
Date and Time: Sunday, May 19, 2024, 2:15 p.m. PT
Location: San Diego Convention Center, Room 24A-C (Upper Level)
ATS 2024, San Diego – For children seeking care at a California urban pediatric health center, extreme heat events were associated with increased asthma hospital visits, according to research published at the ATS 2024 International Conference.
“We found ...
Poor access to in-home nursing for medically complex children quantified
2024-05-20
EMBARGOED UNTIL: 2:15 p.m. PT, Sunday, May 19, 2024
Session: Session A96 – Improving the Care of Patients with Diverse Pulmonary Conditions and Sleep Disordered Breathing
The State of Home Health Nursing for Medically Complex Children in the United States
Date and Time: Sunday, May 19, 2024, 2:15 p.m. PT
Location: San Diego Convention Center, Room 8 (Upper Level)
ATS 2024, San Diego – For American families with medically-complex children, access to home health nursing is often inadequate and the families face major financial burdens, according to research published ...
Hormone Replacement Therapy (HRT) may improve pulmonary hypertension and right ventricular function
2024-05-20
EMBARGOED UNTIL: 2:15 p.m. PT, May 19, 2024
Session: A97 – It’s (Not) a Small World: Molecular and Physiologic Epidemiology in PAH
The Impact of Reproductive History on Pulmonary Hypertension: Insights from the Pvdomics Study
Date and Time: Sunday, May 19, 2024, 2:15 p.m. PT
Location: San Diego Convention Center, Room 6D (Upper Level)
ATS 2024, San Diego – The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference. Pulmonary hypertension (PH) is a type of pulmonary vascular ...
Hospitals caring for diverse patient populations have higher mechanical ventilation mortality
2024-05-20
EMBARGOED UNTIL: 2:39 P.M. PT, May 19, 2024
Session: A93 - CRITICAL CARE AND ACUTE CARE MEDICINE: DISPARITIES, QUALITY IMPROVEMENT, AND OUTCOMES
Examining the Association Between Hospital Environments and Intersectional Disparities in Mechanical Ventilation Outcomes
Date and Time: Sunday May 19, 2024, 2:39 p.m. PT
Location: San Diego Convention Center, Room 7A-B (Upper Level)
ATS 2024, San Diego – The odds of death for patients receiving mechanical ventilation for pneumonia or sepsis increase along with the diversity of hospitals’ patient populations, suggesting more systemic factors such ...
Spirometry clinical trial eligibility may differ with race-neutral equations
2024-05-19
EMBARGOED UNTIL: 9:15 a.m. PT, May 19, 2024
Session: A27 – Emerging Treatments and Therapeutic Strategies in COP: Results of Clinical Trials and Observational Studies
Impact of Race-Neutral Spirometry Reference Equations on Eligibility for Chronic Obstructive Pulmonary Disease Clinical Trials
Date and Time: Sunday, May 19, 9:15 a.m. PT
Location: San Diego Convention Center, Room 33A-C (Upper Level)
ATS 2024, San Diego – Equations that don’t use racially and ethnically adjusted spirometry results to help determine eligibility for chronic obstructive pulmonary disease (COPD) ...
World-first trial shows benefits of finding, treating undiagnosed asthma and COPD
2024-05-19
Finding and treating people with undiagnosed asthma or chronic obstructive pulmonary disease (COPD) improved their health and reduced their healthcare visits for respiratory symptoms in the year after diagnosis, according to a world-first clinical trial published in the New England Journal of Medicine.
"It's estimated that 70 per cent of people with asthma or COPD go undiagnosed." said study lead Dr. Shawn Aaron, a senior scientist and lung specialist at The Ottawa Hospital and professor at the University of ...
Acetaminophen shows promise in warding off acute respiratory distress syndrome, organ injury in patients with sepsis
2024-05-19
A National Institutes of Health (NIH)-supported clinical trial has found that intravenous acetaminophen reduced sepsis patients’ risk of having organ injury or developing acute respiratory distress syndrome, a serious condition that allows fluid to leak into the lungs. Sepsis is the body’s uncontrolled and extreme response to an infection. While the trial did not improve mortality rates in all patients with sepsis regardless of severity, the researchers found that acetaminophen gave the greatest benefit to the patients most at risk for organ damage. With the therapy, those patients needed less assisted ...
Bisoprolol in patients with COPD at high risk of exacerbation
2024-05-19
About The Study: Among people with chronic obstructive pulmonary disease (COPD) at high risk of exacerbation, treatment with the β1-selective β-blocker bisoprolol did not reduce the number of self-reported COPD exacerbations requiring treatment with oral corticosteroids, antibiotics, or both.
Quote from corresponding author Graham Devereux, M.D.:
“People with COPD are at increased risk of cardiovascular conditions that benefit from treatment with beta-blockers. However, there is a well-documented ...
Pamrevlumab for idiopathic pulmonary fibrosis
2024-05-19
About The Study: Among patients with idiopathic pulmonary fibrosis treated with pamrevlumab (a fully human monoclonal antibody that binds to and inhibits connective tissue growth factor activity) or placebo, there was no statistically significant between-group difference for the primary outcome of absolute change in forced vital capacity from baseline to week 48.
Quote from corresponding author, Ganesh Raghu, M.D.:
“Current treatment with the two drugs approved by regulatory agencies ...
Acetaminophen for prevention and treatment of organ dysfunction in critically ill patients with sepsis
2024-05-19
About The Study: In critically ill sepsis patients, treatment with intravenous acetaminophen for 5 days was safe but did not improve the primary end point of days alive and free of any organ support (dialysis, assisted ventilation, and vasopressors) to day 28 compared with placebo.
Corresponding Author: To contact the corresponding author, Lorraine B. Ware, M.D., email Lorraine.ware@vumc.org.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2024.8772)
Editor’s Note: Please see the ...
Measuring lung function more accurately and more equitably
2024-05-19
Removing race from equations that estimate lung function will shift the categorization of disease severity across patient populations, moving more Black individuals into an advanced disease category, according to new research led by scientists at Harvard Medical School. At the same time, more white and Hispanic people would be reclassified as having less advanced illness.
The findings, the research team said, suggest that adjusting lung function tests to include race — as has been the case historically — likely normalized worse lung function and downplayed disease severity among Black people.
The work, to be published May 19 in the New England Journal ...
Study reports ‘excellent’ outcomes for patients receiving optimized treatment for atrial fibrillation
2024-05-18
Atrial fibrillation (AF) is the most common form of arrythmia or irregular heartbeat worldwide, impacting millions of people in the U.S. alone. In a new study published in Heart Rhythm, researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, analyzed real-world clinical data to measure the impact of evidence-based best-practices on patient outcomes for the most common AF procedure: radiofrequency (RF)-based ablation. One year after the procedure, 81.6 percent ...
Modular Communicative Leadless ICD is safe and exceeds performance expectations
2024-05-18
Wireless implantable cardioverter-defibrillators (ICDs) eliminate the lead-related complications that come with a wired ICD, but they are unsuitable for patients with ventricular tachycardia, when the heart beats too quickly, or bradycardia, when the resting heart rate is seen as low. Research led by Amsterdam UMC, that is published today in the New England Journal of Medicine, shows that the first wireless modular system suitable for these patient groups is safe and exceeds performance expectations. Opening the door for a wider ...
Patients seen by female gastroenterologists have significantly less health care utilization than patients seen by male providers
2024-05-18
WASHINGTON, DC (May 18, 2024) — Patients seen by a female gastroenterologist for an initial consultation are less likely to use medical care in the emergency department, hospital or primary care office for two years after their visit when compared to patients initially seen by male gastroenterologists, according to a study to be presented at Digestive Disease Week® (DDW) 2024.
“If there really is something different about the way female and male gastroenterologists provide care that impacts patient outcomes, it will be important to share these learnings broadly among health care providers ...
Iso-propagation vortices: optical multiplexing for unprecedented information capacity
2024-05-17
The future of optical communications just got brighter. In a groundbreaking development reported in Advanced Photonics, researchers from Nanjing University have introduced iso-propagation vortices (IPVs), a novel concept that offers a solution to a long-standing challenge faced by scientists and engineers: how to increase information processing capacity while overcoming the limitations of traditional vortex beams.
Challenge: divergence and beam size
Multiplexing of optical degrees of freedom, such as polarization and wavelength, has been a staple in enhancing communication capacity. ...
Ukraine blackouts caused by malware attacks warn against evolving cybersecurity threats to the physical world
2024-05-17
On a cold winter night in 2016, Ukrainians experienced the first-ever known blackout caused by malicious code (malware) designed to autonomously attack the power grid. One-fifth of Kyiv’s citizens were plunged into darkness as attackers used malware to target the capital city’s power grid. Six years later, in the early months of the ongoing Russia-Ukraine war, a second attack attempted to combine kinetic and cyber attacks to take down Ukraine’s power grid.
Malware attacks against physical ...
How memories crystallize over time
2024-05-17
“Practice makes perfect” is no mere cliché, according to a new study from researchers at The Rockefeller University and UCLA. Instead, it’s the recipe for mastering a task, because repeating an activity over and over solidifies neural pathways in your brain.
As they describe in Nature, the scientists used a cutting-edge technology developed by Rockefeller’s Alipasha Vaziri to simultaneously observe 73,000 cortical neurons in mice as the animals learned and repeated a given task over two weeks. The study revealed that memory representations transform from unstable to solid in ...
Gilbert Family Foundation invests $21 million to launch new research initiative focused on developing advanced disease models to accelerate cure for neurofibromatosis
2024-05-17
New initiative, launched on World NF Awareness Day, focuses on developing improved models to understand neurofibromatosis type 1 (NF1) with the goal of rapidly testing new treatments.
18 grants will be provided to leading medical research institutions in the United States and Europe.
The Next-Generation NF1 Models Initiative is the Foundation’s fourth research initiative focused on accelerating a cure for neurofibromatosis.
DETROIT, May 17, 2024 – Gilbert Family Foundation, a private foundation established by Dan and Jennifer Gilbert to accelerate a cure for ...
Multiple onychopapillomas and BAP1 tumor predisposition syndrome
2024-05-17
About The Study: This study found that BRCA1-associated protein (BAP1) tumor predisposition syndrome was associated with a high rate of nail abnormalities consistent with onychopapillomas (a benign tumor of the nail) in adult carriers of the disease. Findings suggest that this novel cutaneous sign may facilitate detection of the syndrome in family members who are at risk and patients with cancers associated with BAP1 given that multiple onychopapillomas are uncommon in the general population and may be a distinct clue to the presence of a pathogenic germline variant in the BAP1 gene.
Corresponding Authors: To contact the corresponding authors, ...
Researchers confirm scale matters in determining vulnerability of freshwater fish to climate changes
2024-05-17
The silver chub isn’t considered sensitive to climate change on a national scale, but context matters. For example, if climate change sensitivity is evaluated in only one region of the United States, the freshwater fish appears quite a bit more susceptible.
“Relative to other species we looked at in the gulf region of the U.S., the silver chub occupied a pretty small geographic area,” said Samuel Silknetter, a Ph.D. student in biological sciences. “If we didn’t look at the climate sensitivity across multiple ...
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