University of Leeds researchers, funded by Cancer Research UK, have used a library of DNA to create a vaccine that could be used to treat cancer, according to a study published in Nature Medicine. Before now, 'gene therapy' vaccines have often delivered just one gene to stimulate the immune system. It produces a protein, called an antigen, which activates the immune system to destroy cancer cells. It has been difficult to develop successful cancer vaccines because each tumour has specific proteins and identifying the right antigens has been a huge challenge. Scientists ...

New Haven, Conn. — A single gene is central in the development of several forms of polycystic kidney and liver disease, Yale School of Medicine researchers report in the June 19 issue of Nature Genetics. The findings suggest manipulating activity of PKD1, the gene causing the most common form of polycystic kidney disease, may prove beneficial in reducing cysts in both liver and kidney. "We found that these conditions are not the result of an all or nothing phenomenon," said Stefan Somlo, the C.N.H. Long Professor of Medicine and Genetics and Chief, Section of Nephrology ...

More and more now, the IRS officers who pursue back taxes are becoming aggressive and inflexible, demanding payments from taxpayers without regard for their personal situation. Pamela (Fresno, CA) was feeling the pinch from an IRS Revenue Officer who was hammering her to make a payment on the approximately $11,000 she owed to the IRS. At her wits' end, she contacted Blue Tax. The Blue Tax team interviewed Pamela and discovered that the Revenue Officer had given her a deadline to make a $200 payment. They were also able to ascertain that she indeed would be unable ...

SEATTLE – Researchers at Fred Hutchinson Cancer Research Center have demonstrated in mice that the performance of a novel biomarker-development pipeline using targeted mass spectrometry is robust enough to support the use of an analogous approach in humans. The findings, by principal investigator Amanda Paulovich, M.D., Ph.D., an associate member of the Hutchinson Center's Clinical Research Division, are published in Nature Biotechnology. Paulovich and colleagues demonstrated that a staged, targeted pipeline approach using mass spectrometry to prioritize and validate proteins ...

Boston, MA (June 19, 2011)—Mitochondria, those battery-pack organelles that fuel the energy of almost every living cell, have an insatiable appetite for calcium. Whether in a dish or a living organism, the mitochondria of most organisms eagerly absorb this chemical compound. Because calcium levels link to many essential biological processes—not to mention conditions such as neurological disease and diabetes—scientists have been working for half a century to identify the molecular pathway that enables these processes. After decades of failed effort that relied on classic ...

Evans Consoles is pleased to announce they have been chosen as the recipients of the 2011 Best of NeoCon "Innovation" Award, in the "Furniture Workstation Tables" category. Evans products were well received at NeoCon 2011, which is widely considered the "Premier North American event for Interior Design and Facilities Management." The ultimate open architecture solution for maximum sightlines and functionality, Evans' Strategy console has been specifically designed for technology-intensive, 24/7 environments. Strategy offers flexible equipment ...

Breast cancer accounts for almost a third of all cancer cases reported in women. However advances in the treatment for breast cancer, and early detection, have improved the chances of survival from the disease. New research published in BioMed Central's open access journal Breast Cancer Research has found that two thirds of women with breast cancer died from other causes and that over the length of the study cardiovascular disease was the leading cause of death. Breast cancer is now the most common cancer in the UK affecting one in eight women with eight out of ten of ...

Loss of muscle mass is not only associated with disease, such as HIV and cancer, but also with the normal aging process. Anabolic steroids are sometimes used to reverse loss of lean muscle tissue but they can have unwanted side effects. New research, published in BioMed Central's open access journal Immunity and Aging, shows that nine proteins, isolated from blood, alter with age and that the profile of some of these proteins can be reversed by testosterone treatment. In a combined study, researchers from Boston University School of Medicine and University of Texas Medical ...

Designing new materials depends upon understanding the properties of today's materials. One such material, Nafion ©, is a polymer that efficiently conducts ions (a polymer electrolyte) and water through its nanostructure, making it important for many energy-related industrial applications, including in fuel cells, organic batteries, and reverse-osmosis water purification. But since Nafion was invented 50 years ago, scientists have only been able to speculate about how to build new materials because they have not been able to see details on how the molecules come together ...

Heavy and prolonged snowfall can bring about unexpected conditions that encourage fungal growth, leading to the death of plants in the Arctic, according to experts. A new international study confirms that whilst snow has an insulating effect which helps plants to grow bigger, heavy and prolonged snow can, in certain circumstances, also encourage the rapid and extensive growth of killer fungal strains. The research results, published in the journal Nature Climate Change, show for the first time the potential long term effects of unexpected fungal development on an arctic ...

Climate change disasters, such as the melting of the Greenland ice sheet, dieback of the Amazon rainforest or collapse of the Atlantic overturning circulation, could be predicted according to University of Exeter research. Writing in the journal Nature Climate Change, Professor Tim Lenton of the University of Exeter shows that the 'tipping points' that trigger these disasters could be anticipated by looking for changes in climate behaviour. Climate 'tipping points' are small changes that trigger a massive shift in climate systems, with potentially devastating consequences. ...

JACKSONVILLE, Fla. — An international research team, co-led by scientists at Mayo Clinic's campus in Florida, have discovered three potential susceptibility genes for development of progressive supranuclear palsy (PSP), a rare neurodegenerative disease that causes symptoms similar to those of Parkinson's disease but is resistant to Parkinson's medications. Their report is being published online June 19 in Nature Genetics. The findings provide a "testable translational hypothesis" as to the development and progression of PSP and may also provide clues into other more common ...

The release of ExpertPage's iPhone and iPad Application Expert Finder has already been producing results for the highly qualified experts listed on ExpertPages.com, the first and leading online directory for expert witnesses. "The new Expert Finder App enables attorneys, insurance companies, government agencies, and other legal professionals to effortlessly and effectively locate the experts they need from the palm of their hand," said Nicola Fraser, ExpertPages Product Manager. Released just last week, "the new Expert Finder App is just one part of ...

Coming out as lesbian, gay, or bisexual increases emotional well-being even more than earlier research has indicated. But the psychological benefits of revealing one's sexual identity -- less anger, less depression, and higher self-esteem – are limited to supportive settings, shows a study published June 20 in Social Psychology and Personality Science. The findings underscore the importance of creating workplaces and other social settings that are accepting of all people, but especially gay, lesbian or bisexual individuals, says coauthor Richard Ryan, professor of psychology ...

The Offshore Group will host its Manufacturing in Mexico Summit for the 17th consecutive year in the Mexican resort community of San Carlos, Sonora. The gathering of manufacturing executives, one of the maquiladora industry's longest running and most recognized conferences, will be held at the Plaza San Carlos Hotel on the Sea of Cortez from October 20th-22nd. Executives contemplating future Mexico manufacturing projects are invited to attend. The program has been designed so that attendees will gain comprehensive relevant and practical insight into initiating and maintaining ...

Where you get your news could play a significant role in determining what you perceive as the best strategy for addressing childhood obesity. According to a study led by researchers from the Johns Hopkins Bloomberg School of Public Health, whether you believe the keys to combating childhood obesity are personal factors such as individual behavior changes or system-level factors such as marketing and the environment may depend on your primary news source. Researchers examined the news media's framing of childhood obesity and found that television news was more likely than ...

Economists recognize that companies that export are more productive. However, a more complex relationship between exporting and investing in research and development may better explain the high productivity of companies in "economic miracle" countries such as China and Taiwan, according to a team of economists. "The old story is that there's some type of magic that makes your company more productive if it exports," said Bee-Yan Aw, professor of economics, Penn State. "Actually what we found is that really productive firms tend to export in the first place." The researchers, ...

It is always delightful to share your achievements with your friends and colleagues; that is why Lelamed is glad to inform its customers about further improvements and bonuses for its regulars. Due to several months of hard and fruitful work the company managed to raise the cost of its shares considerably despite hardships of the past. These days the pharmaceutical company has already started expanding and refinancing a part of its production and creating new workplaces. To celebrate its recent achievement the pharmacy offers its regular and potential customers the whole ...

AMES, Iowa – Laura Jarboe pointed to a collection of test tubes in her Iowa State University laboratory. Some of the tubes looked like they were holding very weak coffee. That meant microorganisms – in this case, Shewanella bacteria – were growing and biochemically converting sugars into hydrocarbons, said Jarboe, an Iowa State assistant professor of chemical and biological engineering. Some of the sugars in those test tubes were produced by the fast pyrolysis of biomass. That's a thermochemical process that quickly heats biomass (such as corn stalks and leaves) in ...

In Rich Immigrant Poor Citizen, Dr. Singh explores the factors that motivate immigrants and their children to be successful, and defines what truly sets them apart. He asserts that immigrants have made America a stronger nation, and attributes this to the values instilled upon them during childhood. He has drawn upon 37 years of life experience living in the United States. This book reveals an insight as to how immigrants: - See the American Dream while citizens are often blind to it. - Comprise 41 percent of the student populations of Ivy League colleges. - Are ...

Utah Web Design, a Utah Internet marketing firm, is pleased to announce its newest Social Media and Search Engine Optimization (SEO) projects. To begin with, the ever trusted SEO and web developing company shows off its reinforced programs, namely the: Custom Web Design, the Social Media Marketing, the Text Messages Marketing, the Text Based Labor Management, the Local Search Optimization and others. The Social Media Marketing will promulgate your company and its offerings and help it permeate through the social networking sites where lots of consumers stay. The Text ...

As one of the pioneer brands in the shoe manufacturing market, we at Shoes.co.uk provide you with a wonderful range of collections. We are one of the premier brands representing the online shoe selling and supply business in the United Kingdom. We have years of valuable experience in the field and provide you with top quality shoe products all the way. The brand has lived up to its good reputation over the years and served a global pool of customers. The brand started its operation way back in the year 2006 and it all happened due to two enthusiastic entrepreneurs. ...

The UAE has invested substantially in developing its warehousing facilities and transportation infrastructure, making it one of the success stories of the global logistics industry in recent times. Following in its footsteps, operations in neighbouring countries, such as Saudi Arabia, Oman and Bahrain, are now also beginning to flourish. It is evident that the region's trade patterns and logistics development is constantly evolving and over the next year or more the industry will remain in a state of positive change. In a move to bring the region's entire logistics ...

Delectable dishes and homegrown brews are a definite recipe for success which is what Meehan�EUR s Vinings is offering for their Terrapin beer dinner, Monday, June 20th at 7:00 p.m. Executive Chef Branden Holte carefully crafted his menu and painstakingly picked each beer to supplement each course. This $45 meal is sure to please all food eaters and beer drinkers alike. Four Course Menu: Amuse Bouche Homemade Mini Lump Crab Cake Lemon Saffron Yogurt Monk�EUR s Revenge Belgian IPA �EUR" 9.6% 1st Course Roasted Red & Golden Beets Goat Cheese, ...

"My passion for many,many, many years has been to celebrate the writing done in this state. I have been dismayed that Georgia writers have not had the kind of acknowledgement that our neighboring states give their native writers. This occasion tonight does this - gives recognition to our native writers." Terry Kay addressed those gathered for the 47th Annual Georgia Author of the Year Awards on Saturday, June 11, 2011, where he accepted the Lifetime Achievement Award. Kay is the author of several popular novels including To Dance with the White Dog which became ...