Today, Breakthrough Discoveries for thriving with Bipolar Disorder (BD²) announced four new national institutions to receive $2.3 million each to join the BD² Integrated Network, a collaborative research and clinical care model that will improve care, interventions, and outcomes for people living with bipolar disorder. University of Cincinnati/Lindner Center of HOPE, University of California San Diego, The University of Texas at Austin, and The Feinstein Institutes for Medical Research join the six inaugural institutions in the network. Working in partnership with clinicians, researchers, and people living ...

Older adults who lack internet access are at a significantly higher risk of developing depressive symptoms, especially those with limited familial support or lower income levels, according to a new study published in Health Data Science. Conducted by an international team of researchers, this study analyzed data from five major aging cohort studies covering 24 countries, revealing a strong link between digital exclusion and mental health. The researchers, led by Dr. Yinzi Jin from Peking University, investigated how digital exclusion—defined as the lack of internet access—affects the mental health of older adults. Using data from the Health and Retirement Study (HRS), ...

Quantum annealing processors outperform classical supercomputers in solving real-world scientific simulations of quantum spin dynamics, researchers report in a new study, achieving results far beyond the capacity of conventional computational methods, which may require impossible time and energy to match. The results provide a challenge to classical computing, where method improvement has in the past tempered claims of quantum advantage. Only in recent years have quantum computers begun to live up to their lofty promises, with quantum processing units (QPUs) with diverse architectures – such as photonic, neutral-atom, and ...

How UV Radiation Triggers a Cellular Rescue Mission Ultraviolet (UV) radiation from the sun is a well-known cause of DNA damage, which can lead to diseases like skin cancer. But how do our cells repair this damage to protect us? Researchers from Sabanci University, Veysel Oğulcan Kaya and Ogün Adebali, have uncovered a fascinating answer: when DNA is damaged by UV light, our cells reorganize their genetic material in 3D space to prioritize repair, in what might be called a “cellular rescue mission.” A New Look at DNA Repair DNA, the blueprint of ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers from the German Cancer Research Center (DKFZ), the Mannheim Medical Faculty and Columbia University in New York have now published in the journal Nature that hepatic stellate cells control liver metabolism as well as liver regeneration and size. The results of the study could contribute to new therapeutic approaches for liver diseases. The liver is a central organ for carbohydrate and protein metabolism as well as for the detoxification ...

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. This poor prognosis stems from both late detection and the cancer’s notorious capacity to adapt and resist therapy. Now, a study led by researchers at the University of Verona, University of Glasgow, and the Botton-Champalimaud Pancreatic Cancer Centre uncovers a hidden driver of this adaptability: extrachromosomal DNA (ecDNA). A New Player in Pancreatic Cancer The team found that some pancreatic cancer cells gain a major survival edge by carrying copies of critical cancer genes—such as ...

Since the groundbreaking discovery of graphene in 2004, the dizzying pace of progress in two-dimensional (2D) materials has ushered in a new era of fundamental research and technological innovation. Although nearly 2,000 2D materials have been theoretically predicted and hundreds have been created in laboratory settings, most of these 2D materials are limited to van der Waals (vdW) layered crystals.  Scientists have long been keen to develop atomically thin 2D metals, thereby expanding ...

MIS-C is a serious inflammatory shock that affects children. It can occur several weeks after a COVID infection and can be life-threatening. Until now, however, the precise cause of the condition was unknown. Researchers at Charité – Universitätsmedizin Berlin and the German Rheumatology Research Center (DRFZ), an institute of the Leibniz Association, have identified that reactivation of a pre-existing, dormant infection with the Epstein-Barr virus triggers an excessive inflammatory response. The researchers have detailed their findings in an article in Nature.* These insights open the door to new treatment methods, potentially not limited to MIS-C. The majority of children ...

Delft, The Netherlands: Quantum Internet Alliance (QIA) researchers at TU Delft, QuTech, University of Innsbruck, INRIA and CNRS recently announced the creation of the first operating system designed for quantum networks: QNodeOS. The research, published in Nature, marks a major step forward in transforming quantum networking from a theoretical concept to a practical technology that could revolutionize the future of the internet.   “The goal of our research is to bring quantum network technology to all. With QNodeOS we're taking a big step forward. We're making it possible – ...

Our brains use basic ‘building blocks’ of information to keep track of how people interact, enabling us to navigate complex social interactions, finds a new study led by University College London (UCL) researchers. For the study, published in Nature, the researchers scanned the brains of participants who were playing a simple game involving a teammate and two opponents, to see how their brains were able to keep track of information about the group of players. The scientists found that rather ...

ANN ARBOR—Large, undisturbed forests are better for harboring biodiversity than fragmented landscapes, according to University of Michigan research.  Ecologists agree that habitat loss and the fragmentation of forests reduces biodiversity in the remaining fragments. But ecologists don't agree whether it's better to focus on preserving many smaller, fragmented tracts of land or larger, continuous landscapes. The study, published in Nature and led by U-M ecologist Thiago Gonçalves-Souza, comes to a conclusion on the decades-long debate. "Fragmentation is bad," said study author Nate Sanders, U-M professor of ecology and evolutionary biology. ...

Modern communication networks rely on optical signals to transfer vast amounts of data. But just like a weak radio signal, these optical signals need to be amplified to travel long distances without losing information. The most common amplifiers, erbium-doped fiber amplifiers (EDFAs), have served this purpose for decades, enabling longer transmission distances without the need for frequent signal regeneration. However, they operate within a limited spectral bandwidth, restricting the expansion of optical networks. To meet the growing demand for high-speed data transmission, researchers have been seeking ways to develop more powerful, flexible, ...

A recent study by Chinese scientists has revealed the intricate molecular machinery driving energy exchange within chloroplasts, shedding light on a key event in the evolution of plant life. Led by FAN Minrui from the Center for Excellence in Molecular Plant Sciences of the Chinese Academy of Sciences, the research elucidates the structure and function of the ATP/ADP translocator—a crucial member of the nucleotide transporter (NTT) family of proteins—which facilitates the transfer of energy across chloroplast membranes. Their findings were published online in ...

Scientists have long suspected that phosphorene nanoribbons (PNRs) – thin pieces of black phosphorus, only a few nanometres wide –   might exhibit unique magnetic and semiconducting properties, but proving this has been difficult. In a recent study published in Nature, researchers focused on exploring the potential for magnetic and semiconducting characteristics of these nanoribbons. Using techniques such as ultrafast magneto-optical spectroscopy and electron paramagnetic resonance they were able to demonstrate the magnetic behaviour of PNRs at room temperature, and show how these magnetic properties can interact with light. The ...

HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Study offers insights into evolutionary process driving pancreatic cancer Read summary | Read study in Nature Pancreatic cancer is hard to treat because ...

Gold nanoparticles (AuNPs) are tiny gold particles of 1–100 nanometers and have unique chemical and biological properties. Due to their potential to accumulate in tumors, these nanoparticles have emerged as promising drug carriers for cancer therapy and targeted drug delivery. However, tracking the movement of these nanoparticles in the body has been a major challenge. Traditional imaging methods often involve tracers like fluorescent dyes and radioisotopes, which give limited visualization and inaccurate results due to detachment from AuNPs. In a step to advance the imaging of AuNPs, researchers from Waseda ...

SAN ANTONIO — March 12, 2025 — Four small suitcase-sized spacecraft, designed and built by Southwest Research Institute headquartered in San Antonio, launched from Vandenberg Space Force Base in California on March 11. NASA’s Polarimeter to Unify the Corona and Heliosphere, or PUNCH, constellation has spread out in a low-Earth orbit along the day-night line, providing a clear view in all directions for its two-year primary mission. “The PUNCH spacecraft are now drifting into perfect position to study the solar corona, the Sun’s outer ...

In developing hearts, cells shuffle around, bumping into each other to find their place, and the stakes are high: pairing with the wrong cell could mean the difference between a beating heart and one that falters. A study publishing on March 12 in the Cell Press journal Biophysical Journal demonstrates how heart cells go about this “matchmaking” process. The researchers model the intricate movements of these cells and predict how genetic variations could disrupt the heart development process in fruit flies. In both humans and fruit flies, the heart’s tissues arise from two distinct regions of ...

Study compares those with food insecurity to food-secure individuals over 20 years Food insecurity is associated with a 41% increased risk of heart disease over time Findings suggest food security screening as a key tool to prevent heart disease CHICAGO --- Struggling to afford food today could mean heart problems tomorrow. Young adults experiencing food insecurity have a 41% greater risk of developing heart disease in midlife, even after accounting for demographic and socioeconomic factors, according to a new Northwestern Medicine study. Food insecurity — struggling to get enough nutritious ...

About The Study: In this prospective cohort study among participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study, food insecurity was associated with incident cardiovascular disease (CVD) even after adjustment for socioeconomic factors, suggesting that food insecurity may be an important social deprivation measure in clinical assessment of CVD risk. Whether interventions to reduce food insecurity programs can potentially alleviate CVD should be further studied.  Corresponding Author: To contact the corresponding author, Jenny Jia, MD, MSc, email jenny.jia@northwestern.edu. To access the embargoed study: ...

About The Study: This cohort study found that healthier diets and lower waist to hip ratio throughout midlife were associated with better brain and cognitive health in older age. The findings suggest that interventions to improve diet and manage central obesity might be most effective between ages 48 and 70. Corresponding Author: To contact the corresponding author, Daria E. A. Jensen, DPhil, email jensen@cbs.mpg.de. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.0171) Editor’s Note: Please see the article for additional information, ...

Background and objectives Gastrointestinal endoscopy has revolutionized the entire practice of gastroenterology worldwide, including Nigeria. Endoscopy was introduced in Nigeria more than four decades ago, and it has been a story of varying successes and challenges. This study explored the various experiences of endoscopists, the challenges they face, and the efforts put in place to maintain the practice in Nigeria. Methods This cross-sectional survey was conducted from October to December 2023 among endoscopists practicing ...

Toronto, ON, March 12, 2025—Transgender and gender diverse individuals who were hospitalized for psychiatric care were less likely to have a follow-up visit compared to the general population, suggesting they face transphobia in the hospital system.    In a new study from ICES and the Centre for Addiction and Mental Health (CAMH), findings demonstrate that transgender and gender diverse (TGD) people face an interesting paradox:  they have lower access to appropriate mental health care and support following a psychiatric hospitalization, yet have better follow-up after an emergency department (ED) visit. According to Statistics Canada, TGD people account ...

“Notably, the findings from this work may provide novel insight into the underlying mechanisms of PAD and, perhaps, have prevention or therapeutic impacts.” BUFFALO, NY — March 12, 2025 — A new research paper was published in Aging (Aging-US) on February 25, 2025, Volume 17, Issue 2, titled “Epidemiology and genetic determination of measures of peripheral vascular health in the Long Life Family Study.” Researchers from multiple institutions, led by first author and corresponding author ...

A recent review published in Engineering delves into the complex relationships among food systems, climate change, and air pollution, highlighting the need for sustainable strategies to address these interconnected global challenges. Climate change and air pollution pose significant threats to food systems. Rising temperatures, altered precipitation patterns, and extreme weather events, driven by climate change, disrupt agricultural production. For example, higher temperatures and shifting precipitation patterns have altered crop growth cycles, caused yield fluctuations, and increased uncertainty ...