Thomas Jefferson University has initiated a phase 1 clinical trial for a Lassa virus (LASV) vaccine developed at Jefferson in collaboration with the University of Maryland, Baltimore (UMB), at the Center of Vaccine Development and Global Health, UMB. Currently, there are no approved vaccines against the Lassa virus. The clinical study is a dose-ranging study that will assess the safety and immunogenicity of the candidate vaccine for both the rabies virus and LASV. The experimental vaccine is based on an attenuated and killed rabies virus vaccine similar to current rabies vaccines and has an additional ...

Outpatient primary care clinics at Hebrew SeniorLife’s Orchard Cove and NewBridge on the Charles communities have been recognized by the Institute for Healthcare Improvement (IHI) as Age-Friendly Health Systems — Committed to Care Excellence. “I want to express my gratitude to the team at Hebrew SeniorLife for your dedication to age-friendly care,” said Leslie Pelton, MPA, Vice President, Institute for Healthcare Improvement (IHI). “Age-Friendly Health Systems and IHI celebrate your recognition as an Age-Friendly ...

For decades, atomic clocks have been the pinnacle of precision timekeeping, enabling GPS navigation, cutting-edge physics research, and tests of fundamental theories. But researchers at JILA, led by JILA and NIST Fellow and University of Colorado Boulder physics professor Jun Ye, in collaboration with the Technical University of Vienna, are pushing beyond atomic transitions to something potentially even more stable: a nuclear clock. This clock could revolutionize timekeeping by using a uniquely low-energy transition within the nucleus of a thorium-229 atom. This transition is less sensitive to environmental disturbances than modern atomic clocks and has been proposed for tests of fundamental ...

FOR IMMEDIATE RELEASE Monday, March 17, 2025 Contact: Jillian McKoy, jpmckoy@bu.edu  Michael Saunders, msaunder@bu.edu  ##  As health complications and deaths from alcohol use disorder (AUD) increase in the United States, it is critical that people who could benefit from medications have access to the drugs that the US Food and Drug Administration has approved to treat AUD. Yet, for individuals who have alcohol use disorder and are covered by Medicaid, accessing these medications is difficult; past research indicates that only about 1 in 20 Medicaid enrollees with alcohol use disorder receive these ...

Mount Sinai Researchers Find Specific Therapy That Teaches Patients to Tolerate Stomach and Body Discomfort Improved Functional Brain Deficits Linked to Visceral Disgust That Can Cause Food Avoidance in Adolescent Females with Anorexia Nervosa and other Low-Weight Eating Disorders Corresponding Author:  Kurt P. Schulz, PhD, Associate Professor, Center of Excellence in Eating and Weight Disorders, Icahn School of Medicine at Mount Sinai, New York, and other co-authors Bottom Line: A trial of interoceptive exposure - a therapy that teaches patients how to tolerate stomach and body discomfort in order to reduce restrictive eating - improved functional deficits in a brain region ...

Follow @Annalsofim on X, Facebook, Instagram, threads, and Linkedin         Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf ...

18th March 2025, Sydney: In an Australian first, a team of scientists led by Australian Museum and UNSW Sydney palaeontologist, Dr Matthew McCurry, have described a new species of 15-million-year-old fossilised freshwater fish, Ferruaspis brocksi, that shows preserved stomach contents as well as the pattern of colouration. The research is published today in The Journal of Vertebrate Palaeontology (DOI - 10.1080/02724634.2024.2445684) Named after Professor Jochen J. Brocks from the Australian National University, who discovered several of the fossilised species at the Australian Museum’s, McGraths Flat fossil site near Gulgong, NSW, Ferruaspis brocksi is the first ...

  EMBARGOED UNTIL 3/17/2025, 3:00PM ET   March 17, 2025   Slow, Silent ‘Scream’ of Epithelial Cells Detected for First Time Team from UMass Amherst uncovers communication by “electric spiking” in cells once thought to be mute, which could enable bioelectric applications   AMHERST, Mass. — It has long been thought that only nerve and heart cells use electric impulses to communicate, while epithelial cells — which compose the linings of our skin, organs ...

Modern birds are the living relatives of dinosaurs. Take a look at the features of flightless birds like chickens and ostriches that walk upright on two hind legs, or predators like eagles and hawks with their sharp talons and keen eyesight, and the similarities to small theropod dinosaurs like the velociraptors of Jurassic Park fame are striking. Yet birds differ from their reptile ancestors in many important ways. A turning point in their evolution was the development of larger brains, which in turn led to changes in the size and shape of their skulls. New research from ...

Iguanas have often been spotted rafting around the Caribbean on vegetation and, ages ago, evidently caught a 600-mile ride from Central America to colonize the Galapagos Islands. But for long distance travel, the Fiji iguanas can't be touched. A new analysis conducted by biologists at the University of California, Berkeley, and the University of San Francisco (USF) suggests that sometime after about 34 million years ago, Fiji iguanas landed on the isolated group of South Pacific islands after voyaging 5,000 miles from the western coast of North America — the longest known transoceanic dispersal of any terrestrial vertebrate. Overwater ...

UNIVERSITY PARK, Pa. — It may someday be possible to listen to a favorite podcast or song without disturbing the people around you, even without wearing headphones. In a new advancement in audio engineering, a team of researchers led by Yun Jing, professor of acoustics in the Penn State College of Engineering, has precisely narrowed where sound is perceived by creating localized pockets of sound zones, called audible enclaves. In an enclave, a listener can hear sound, while others standing nearby cannot, even if the people are in an enclosed space, like a vehicle, or standing ...

By taking two flakes of special materials that are just one atom thick and twisting them at high angles, researchers at the University of Rochester have unlocked unique optical properties that could be used in quantum computers and other quantum technologies. In a new study published in Nano Letters, the researchers show that precisely layering nano-thin materials creates excitons—essentially, artificial atoms—that can act as quantum information bits, or qubits. “If we had just a single ...

Backgrounds and objectives Gastrointestinal complications are common in patients after ischemic stroke. Gastric motility is regulated by gastric pace-making activity (also called gastric myoelectrical activity (GMA)) and autonomic function. The aim of this study was to evaluate GMA, assessed by noninvasive electrogastrography (EGG), and autonomic function, measured via spectral analysis of heart rate variability derived from the electrocardiogram in patients with ischemic stroke. Methods EGG and electrocardiogram were simultaneously recorded in both fasting and postprandial states in 14 patients with ischemic stroke and 11 healthy controls. ...

The American College of Cardiology (ACC) has issued its first Concise Clinical Guidance (CCG) to create more streamlined and efficient processes to implement best practices in patient care. This CCG focuses on evaluating and managing cardiogenic shock (CS), addressing important questions around clinical decision-making and providing actionable guidance for health care providers. “ACC has a long history of developing clinical policy to complement clinical practice guidelines and to inform clinicians about areas where evidence is new and evolving or where randomized data is more limited. Despite this, ...

A new analysis led by surgeons at UCLA Health finds that psychological prehabilitation can significantly enhance recovery after surgery. The research, led by Anne E. Hall in the lab of Dr. Justine Lee analyzed data from 20 randomized controlled trials (RCTs) conducted between 2004 and 2024, involving a total of 2,376 patients. It is published in the Annals of Surgery What is Psychological Prehabilitation? Prehabilitation is a proactive approach aimed at improving surgical outcomes through preventive measures. Traditionally, ...

Trial of strength at the cellular level: cells are in constant competition with each other and so eliminate diseased or unwanted cells. Cell competition is therefore a central principle for maintaining the health of tissues and organs. Researchers have investigated the success factors of superior cells and discovered a previously unknown winning strategy in mechanical cell competition. They identified a variety in the ability of cells to exert mechanical forces onto other cells as the decisive regulator. With their results ...

Milan, Italy – March 2025 – The Italian Association of Science Writers, SWIM, has announced an extension of the application deadline for the 2025 SWIM Award. Candidates now have until March 31, 2025, at 23:59 CET to submit their applications for the prestigious award, which has been recognizing excellence and innovation in science journalism in Italy since 2021. The SWIM Award highlights the critical role of science journalists in fostering public understanding and dialogue on scientific issues. The competition also serves as the Italian selection process for the European ...

On first inspection, the Cuban blue-headed quail dove doesn’t look like much: drab brown feathers, a slender beak, a pronounced strut in their walk typical of most other doves. You’d be forgiven for overlooking it in favor of Cuba’s prismatic parrots. But looks aren’t everything. For decades, this unassuming bird has perplexed biologists, who have no idea where it came from, how it got to the island or what it’s related to. Now, for the first time, scientists have sequenced DNA from the blue-headed quail dove with the goal of finally getting to the bottom of things. Instead, they’re even more perplexed now than when they started. “This ...

The Vrije Universiteit Brussel (VUB) is opening 12 postdoctoral positions for international researchers, with a specific focus on American scholars working in socially significant fields. These prestigious fellowships come with substantial funding (€2.5 million) as part of the European Marie Skłodowska-Curie (MSCA) program. Additionally, as part of the Brains for Brussels initiative, VUB aims to actively attract American professors looking to relocate. In collaboration with its Francophone sister university ULB, VUB is also providing 18 apartments for international ...

Researchers have widely accepted that what sets humans apart from nonhuman primates are prefrontal cortex–driven behaviors such as decision-making, reasoning, planning, and attention. In a new JNeurosci paper, research led by Rogier Mars, at University of Oxford, and Katherine Bryant, at Aix-Marseille University, provides a better picture of the cortical evolution that distinguishes human brains from other primates.   The researchers compared cortical organization not only between humans and macaques, which is a standard for human and nonhuman primate ...

How stress impacts behavioral outcomes of traumatic brain injury (TBI) represents a major gap in knowledge. This oversight is especially felt by those in the military due to the high prevalence of TBI and the abundance of stress that they endure. In a study funded by the US Department of Defense, researchers led by Pamela VandeVord at Virginia Tech discovered that prior stress exposure influences TBI outcomes in a sex-dependent manner.   In their eNeuro paper, VandeVord and colleagues used an unpredictable stress paradigm ...

MIAMI, FLORIDA (EMBARGOED UNTIL MARCH 17, 2025, AT NOON EDT) – Glioblastoma has remained one of the toughest cancers to treat, resisting even the latest advances in immunotherapy. But new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, suggests a way forward: suppressing a protein called ZNF638 triggers an antiviral immune response, making immune checkpoint inhibitors more effective. The discovery not only offers a potential new treatment strategy but also identifies ...

In a randomized trial, Mass General Brigham researchers found the surgical removal of tonsils and adenoids was effective for children with snoring and mild sleep apnea An estimated 6 to 17 percent of children have sleep-disordered breathing, ranging from snoring to sleep apnea, which can cause behavioral, neurocognitive, cardiovascular, and cardiometabolic issues. A new study from Mass General Brigham researchers reveals that adenotonsillectomy—the surgical removal of tonsils and adenoids—is an effective early intervention for these children. Their results are published in JAMA Pediatrics. “To ...

About The Study: This cohort study found that statin use was associated with a reduced risk of hepatocellular carcinoma and hepatic decompensation in patients with chronic liver disease. These findings provide support for the potential role of statins in prevention of hepatocellular carcinoma and liver disease progression.  Corresponding Authors: To contact the corresponding authors, email Jonggi Choi, MD, PhD, (j.choi@amc.seoul.kr) and Raymond T. Chung, MD, (chung.raymond@mgh.harvard.edu). To ...

About The Study: In this longitudinal observational cohort study, gender-affirming hormone therapy was associated with lower rates of moderate-to-severe depressive symptoms, highlighting the importance of gender-affirming primary care models for transgender, nonbinary, and gender diverse patients. Corresponding Author: To contact the corresponding author, Sari L. Reisner, ScD, MA, email sreisner@umich.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.0955) Editor’s ...