WASHINGTON, DC—Orthopaedic surgeons from Children's National Medical Center are part of a team of researchers that has identified the genetic mutation causing Proteus syndrome, a rare disorder in which tissue and bone grow massively out of proportion. The discovery appears in the July 27, 2011, online edition of the New England Journal of Medicine. The study, led by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), may have larger implications in both the identification and treatment of Proteus syndrome, ...

Atlanta's Hartsfield-Jackson International Airport (ATL), one of the world's busiest international airports is also the most fiscally efficient, says an aviation think-tank based at the University of British Columbia's Sauder School of Business. ATL generated 60 per cent of its total revenue from non-aviation activities, compared to the lowest-ranked North American airport Chicago's O'Hare International Airport (ORD), which derived only 34 per cent of its income from alternative sources. The Air Transport Research Society (ATRS), headquartered at Sauder, has released ...

Algae-based fuel is one of many options among the array of possible future energy sources. New University of Virginia research shows that while algae-based transportation fuels produce high energy output with minimal land use, their production could come with significant environmental burdens. For farmers looking to maximize profits, algae would produce considerably more transportation energy than canola and switch grass for every hectare planted, and can also be grown on poor-quality marginal land that cannot be easily used to grow food crops such as corn, according ...

CHICAGO --- Being physically active is one of best ways people with arthritis can improve their health, but a new study from Northwestern University Feinberg School of Medicine shows that more than half of women and 40 percent of men with arthritis are virtually couch potatoes. This is the first study to use a device to objectively measure the physical activity of people with arthritis and determine if they meet federal guidelines. Past research relied on self-reported accounts of exercise and activity. The study was published in Arthritis & Rheumatism, August 2011. Researchers ...

This release is available in French. Dr. John Rioux, researcher at the Montreal Heart Institute, Associate Professor of Medicine at the Université de Montréal and original co-founder of the International Multiple Sclerosis Genetics Consortium is one of the scientists who have identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of a very debilitating neurological disease. Many of the genes implicated in the study are relevant to the immune system, shedding light onto the immunological pathways that underlie the development ...

A UCSF-led pilot study in San Francisco has found the highest levels ever reported among pregnant women worldwide of banned chemicals used in flame retardants, a likely result, they believe, of California's strict flammability regulations. Polybrominated diphenyl ethers (PBDEs) were added to consumer products, such as electronics and foam in furniture beginning in the 1970s. The chemicals slow ignition and the rate at which a fire grows, according to the US Environmental Protection Agency (EPA). Tests indicate that these chemicals may cause liver, thyroid, and neurodevelopmental ...

Biologists and psychologists know that light affects mood, but a new University of Virginia study indicates that light may also play a role in modulating fear and anxiety. Psychologist Brian Wiltgen and biologists Ignacio Provencio and Daniel Warthen of U.Va.'s College of Arts & Sciences worked together to combine studies of fear with research on how light affects physiology and behavior. Using mice as models, they learned that intense light enhances fear or anxiety in mice, which are nocturnal, in much the same way that darkness can intensify fear or anxiety in diurnal ...

URBANA – Dieting postmenopausal women who want to avoid losing muscle as they lose fat should pay attention to a new University of Illinois study. Adding protein throughout the day not only holds hunger pangs at bay so that dieters lose more weight, it keeps body composition—the amount of fat relative to muscle—in better proportion. "A higher-protein weight-loss diet is more protective of muscle," said Ellen Evans, a former U of I associate professor of kinesiology and community health and member of the university's Division of Nutritional Sciences. Scientists in Evans's ...

DALLAS – Aug. 10, 2011 – People who frequently use tanning beds may be spurred by an addictive neurological reward-and-reinforcement trigger, researchers at UT Southwestern Medical Center have found in a pilot study. This could explain why some people continue to use tanning beds despite the increased risk of developing melanoma, the most lethal form of skin cancer. The brain activity and corresponding blood flow tracked by UT Southwestern scientists involved in the study is similar to that seen in people addicted to drugs and alcohol. "Using tanning beds has rewarding ...

PHILADELPHIA—Pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time, that blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme AMPK to inhibit fatty acid synthase, the ingredients to support cell division. With that, a new chemopreventive agent that inhibits the angiotensin II type 2 receptor—never before thought to play a role in tumor growth—could be developed to help treat one of the fastest-moving cancers that has a 5-year survival rate of only 5 percent. Hwyda ...

Reaching a new threshold in underwater medical studies, the Office of Naval Research (ONR), today announced a novel capability for examining how cells work at pressures far below the sea surface. Researchers at the Navy Experimental Diving Unit (NEDU) have designed, built and validated a novel hyperbaric environment to study cellular behavior at greater depths. The joint ONR-NEDU effort is designed to explore advances to protect Navy divers working at depths of up to 1,000 feet. "This is a huge leap forward in our ability to understand cellular function at pressurized ...

With its promise to give us everything that makes sense, a group of young, self-proclaimed tech-geeks is gearing up to announce the launch of their new website this week. Shawcapitalmanagementonline.com, a product of a 6-month long development effort by the innovative founders themselves, is expected to make its way to the mainstream roster of news providers online. The new website features relevant news stories that focuses on Technology, Finance and Lifestyle and an area where you can interact with fellow readers and discuss stuff. Analysis shows that online users ...

MADISON, WI, AUGUST 10, 2011 -- Golf courses, known for their calm scenic views and precise grass patterns, take daily abuse. Divots created by golf strokes are a common occurrence, and can be a costly problem for golf course maintenance operations. Although previous research has identified differences in divot recovery across species of bermudagrass and zoysiagrass, little is known about divot resistance. Scientists at Purdue University and the University of Arkansas evaluated 12 cultivars of bermudagrass and zoysiagrass in a field experiment conducted in Fayetteville, ...

A revolutionary material that will replace steel in warhead casings will bring added lethality and increase the likelihood of a hit on an enemy target, the Office of Naval Research (ONR) announced August 10. By combining several metals with standard manufacturing techniques, High-Density Reactive Material (HDRM) has the potential to dramatically increase the explosive impact of most weapons with little or no compromise in strength or design. Unlike conventional munitions, the innovative materials approach integrates the casing with approved warhead explosives for increased ...

Commercial blood serum antibody tests—widely used in India and other developing countries to diagnose active tuberculosis—are not accurate or cost-effective, according to an analysis by researchers at the Johns Hopkins Bloomberg School of Public Health, the University of Washington School of Public Health and McGill University. Use of serological tests in India resulted in more DALYs (years of healthy life lost to premature death and illness), more secondary infections, and more false-positive diagnoses of TB, compared to the use of microscopic sputum smear analysis or ...

TORONTO – New research led by The Hospital for Sick Children (SickKids) and the University of Toronto has identified more genes in attention deficit hyperactivity disorder (ADHD) and shows that there is an overlap between some of these genes and those found in other neuropsychiatric conditions such as autism spectrum disorder (ASD). The study is published in the August 10 advance online edition of Science Translational Medicine. The research team was led by Dr. Russell Schachar, Senior Scientist and Psychiatrist at SickKids and Professor of Psychiatry at the University ...

For decades, scientists have studied a laboratory mouse model that develops signs of the paralyzing disease amyotrophic lateral sclerosis (ALS) as they age. In a new study appearing in Nature Biotechnology, investigators at Nationwide Children's Hospital have developed a new model of ALS, one that mimics sporadic ALS, which represents about 90 percent of all cases. ALS, commonly known as Lou Gehrig's disease, is characterized by the death of motor neurons, which are muscle-controlling nerve cells in the spinal cord. As these neurons die, the body's voluntary muscles ...

ANN ARBOR, Mich.---A study links low vitamin D in young girls with early menstruation, which is a risk factor for a host of health problems for teen girls as well as women later in life. Researchers from the University of Michigan School of Public Health measured the blood vitamin D levels in 242 girls ages 5-12 from Bogota, Colombia, and followed them for 30 months. Girls low on vitamin D were twice as likely to start menstruation during the study than those with sufficient vitamin D, said epidemiologist Eduardo Villamor, associate professor in the U-M SPH. This ...

Golf courses and coffee plantations are some of the unlikely bat habitats that could be considered in conservation plans, say scientists presenting research at the Ecological Society of America's (ESA) 96th Annual Meeting from August 7-12, 2011. Using Doppler weather radar and other technologies relatively new to the field of ecology, ecologists will discuss the role of atmospheric conditions in bat behavior and the effectiveness of acoustic deterrents in reducing bat fatalities at wind farms. ESA's August 2011 meeting will take place in Austin, Texas, home to North America's ...

Analyses of the metabolic profile of blood serum have revealed significant differences in metabolites between men and women. In a study to be published on August 11 in the open-access journal PLoS Genetics, scientists at the Helmholtz Zentrum München have concluded that there is a need for gender-specific therapies. Gender-specific therapies may be required for some diseases as there are significant differences between male and female metabolism. Such differences were shown to exist for 101 of the 131 metabolites – above all in lipid and amino acid species – in the sera ...

AUSTIN, Texas – Just as the rainy season is driving a new surge of cholera cases in Haiti, a new computational model could forecast where outbreaks are likely to occur. Researchers at Ohio State University are working with the Centers for Disease Control and Prevention (CDC) on the project, in the hopes of targeting anti-cholera efforts where they are most needed in the earthquake-ravaged country. Just back from a 10-day trip to the Artibonite Valley in Haiti, Ohio State researcher Marisa Eisenberg described the model's early results at the Ecological Society of America ...

Ice and frozen ground at the North and South Poles are affected by climate change induced warming, but the consequences of thawing at each pole differ due to the geography and geology, according to a Penn State hydrologist. "The polar regions, particularly the Arctic, are warming faster than the rest of the world," Michael N. Gooseff, associate professor of civil and environmental engineering, told attendees today (Aug. 11) at the 96th annual meeting of the Ecological Society of America in Austin, Texas. "As a consequence, polar ecosystems respond directly to changes ...

In both chimpanzees and humans, portions of the brain that are critical for complex cognitive functions, including decision-making, self-awareness and creativity, are immature at birth. But there are important differences, too. Baby chimpanzees don't show the same dramatic increase in the volume of prefrontal white matter in the brain that human infants do. Those are the conclusions of a study reported in the August 11th Current Biology, a Cell Press publication, that is the first to track the development of the chimpanzee brain over time and to make the comparison to ...

Bacteria may have bad reputations but in fact, all animals -- us included -- rely on them in critical ways. In the case of sap-feeding insects, intimate associations with microbes offer a source for essential nutrients that their sugary diets just don't include. Now, researchers reporting in the August 11th Current Biology, a Cell Press publication, have new insight into organisms that have taken this symbiotic lifestyle to the extreme; they have sequenced the genomes of two species of bacteria that live together, one inside of the other, inside mealybugs. The effort ...

RICHLAND, Wash. -- Looking to nature for their muse, researchers have used a common protein to guide the design of a material that can make energy-storing hydrogen gas. The synthetic material works 10 times faster than the original protein found in water-dwelling microbes, the researchers report in the August 12 issue of the journal Science, clocking in at 100,000 molecules of hydrogen gas every second. This step is just one part of a series of reactions to split water and make hydrogen gas, but the researchers say the result shows they can learn from nature how to control ...