SAN ANTONIO — A higher prescription co-payment, especially among older women, is associated with both early discontinuation and incomplete use of adjuvant aromatase inhibitor therapy, a life-saving therapy for women with hormone sensitive early-stage breast cancer. Dawn L. Hershman, M.D., M.S., associate professor of medicine and epidemiology and co-director of the Breast Cancer Program at the Herbert Irving Comprehensive Cancer Center at Columbia University, presented detailed study results at the 33rd CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12, ...

SAN ANTONIO — Do not delay treatment of breast cancer just because a woman is pregnant, said lead researcher Sibylle Loibl, Dr. med, of the German Breast Group. This suggestion is based on study results detailing the effects of different treatment options on the infant. Loibl presented this data at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12, 2010. "At the time we started the study in 2003, there was hardly any information on breast cancer therapy during pregnancy, but we felt there was a medical need for it," she said. Although ...

SAN ANTONIO -- With guidance from a specialized scan, radiation oncologists at Mayo Clinic (http://www.mayoclinic.org/) were able to reduce by 55 percent the number of lymph nodes critical for removing fluid from the arm that received damaging radiation doses. VIDEO ALERT: Additional audio and video resources, including excerpts from an interview with Dr. Andrea Cheville and other researchers presenting at San Antonio Breast Cancer Symposium, are available on the Mayo Clinic News Blog (http://newsblog.mayoclinic.org/2010/12/06/lymphedema-study/). These materials also ...

SAN ANTONIO -- Results for testing breast tumors for HER2 (http://www.mayoclinic.com/health/breast-cancer/AN00495) proteins and genes is most often straightforward when one piece of tumor (a single tumor block) is analyzed. However, tumors can be diverse, and researchers at Mayo Clinic (http://www.mayoclinic.org/) found that HER2 results can vary in up to 10 percent of patients when several tumor blocks are analyzed. This could have significant implications for patient treatment, say the researchers, who are presenting their findings at the 33rd Annual CTRC-AACR San ...

A higher prescription co-payment, especially among older women, is associated with both early discontinuation and incomplete use of adjuvant aromatase inhibitor therapy, a life-saving therapy for women with hormone sensitive early stage breast cancer. Dawn L. Hershman, MD, associate professor of medicine and epidemiology and co-director of the Breast Cancer Program at the Herbert Irving Comprehensive Cancer Center at Columbia University, will be presenting detailed study results at The 33rd CTRC-AACR San Antonio Breast Cancer Symposium, a comprehensive scientific meeting ...

ANN ARBOR, Mich. — A drug commonly used to treat depression and anxiety disorder was effective at reducing joint and muscle pain associated with a breast cancer treatment, according to a study from the University of Michigan Comprehensive Cancer Center. The women in the study were taking aromatase inhibitors, a type of drug designed to block the production of estrogen, which fuels some breast cancers. About half of women taking these drugs experience aches and pains in their joints and muscles that cannot be adequately relieved by over-the-counter painkillers. Up to 20 ...

Blocking fragments of the sugar molecule hyaluronan that triggers inflammation could be the key to robust healing and less scarring in deep wounds, Canadian researchers reported at the American Society for Cell Biology's 50th Annual Meeting in Philadelphia. In laboratory rats, the small peptide, named 15-1, which blocks fragments of the ubiquitous sugar molecule, hyaluronan, promoted wound healing, minimized scarring and forged stronger new tissue. These effects did not occur in the untreated animals in the study, according to Cornelia Tölg, Ph.D., of the London (Ontario) ...

Researchers at the University of California, Riverside (UCR), have identified components in pomegranate juice that seem to inhibit the movement of cancer cells and weaken their attraction to a chemical signal that has been shown to promote the metastasis of prostate cancer to the bone, according to a presentation today at the American Society for Cell Biology's 50th Annual Meeting in Philadelphia. The researchers in the UCR laboratory of Manuela Martins-Green, Ph.D., plan additional testing in an in vivo model for prostate cancer to determine dose-dependent effects and ...

Insulin-secreting pancreatic islet cells have been generated from human spermatogonial stem cells (SSCs) directly isolated from human testicular tissue, researchers reported today at the American Association of Cell Biology 50th Annual Meeting in Philadelphia. When grafted into diabetic mice that lacked a transplant-rejecting immune system, the bioengineered cells functioned much like somatic β-islet cells, the Georgetown University (GU) Medical Center researchers said. By decreasing the animals' blood glucose levels, the human-derived islet cells demonstrated ...

PHILADELPHIA – Men with type 1 diabetes may be able to grow their own insulin-producing cells from their testicular tissue, say Georgetown University Medical Center (GUMC) researchers who presented their findings today at the American Society of Cell Biology 50th annual meeting in Philadelphia. Their laboratory and animal study is a proof of principle that human spermatogonial stem cells (SSCs) extracted from testicular tissue can morph into insulin-secreting beta islet cells normally found in the pancreas. And the researchers say they accomplished this feat without use ...

In the burgeoning field of nano-science there are now many ways of 'writing' molecular-scale messages on a surface, one molecule at a time. The trouble is that writing a molecule at a time takes a very long time. "It is much better if the molecules can be persuaded to gather together and imprint an entire pattern simultaneously, by themselves. One such pattern is an indefinitely long line, which can then provide the basis for the ultimately thin molecular 'wire' required for nano-circuitry," says John Polanyi of the University of Toronto's Department of Chemistry, co- ...

Research published today identifies two genetic variants that increase the risk of developing endometriosis, a common gynaecological disease. The study provides clues to the origin of this often very painful condition, which has a significant impact on the quality of life of sufferers. Details of the research, carried out at the Wellcome Trust Centre for Human Genetics and the Nuffield Department of Obstetrics & Gynaecology, University of Oxford; the Queensland Institute of Medical Research, Australia, and Brigham; and Women's Hospital and Harvard Medical School, Boston, ...

Simulations performed at Southwest Research Institute may explain how Saturn's majestic rings and icy inner moons formed following the collision of a Titan-sized satellite with the planet, according to a paper published in Nature magazine's Dec. 12 Advance Online Publication. Saturn's rings are at present 90 to 95 percent water ice. Because dust and debris from rocky meteoroids have polluted the rings, the rings are believed to have consisted of pure ice when they formed. This composition is unusual compared to the approximately half-ice and half-rock mixture expected ...

CINCINNATI –For the first time, scientists have created functioning human intestinal tissue in the laboratory from pluripotent stem cells. In a study posted online Dec. 12 by Nature, scientists from Cincinnati Children's Hospital Medical Center say their findings will open the door to unprecedented studies of human intestinal development, function and disease. The process is also a significant step toward generating intestinal tissue for transplantation, researchers say. "This is the first study to demonstrate that human pluripotent stem cells in a petri dish can be ...

A team led by Massachusetts General Hospital (MGH) researchers has developed a faster way to engineer synthetic enzymes that target specific DNA sequences for inactivation, repair or alteration. The report from the MGH Molecular Pathology Unit, being published online in Nature Methods, describes a highly effective but less labor-intensive way to generate powerful tools called zinc-finger nucleases (ZFNs). "With our approach, called context-dependent assembly, any scientist can use either standard molecular biology techniques or commercial DNA synthesis to design ZFNs ...

BIRMINGHAM, Ala. – University of Alabama at Birmingham researchers have pinpointed a protein that compromises the kidney's filtering ability, causing nephrotic syndrome, and demonstrated that a naturally occurring precursor of an acid in the body offers potential for treating some forms of the condition. The research was published online Dec. 12 in Nature Medicine. "This is a major breakthrough in understanding the development and treatment of kidney disease associated with proteinuria, the leakage of protein in the urine," said the study's lead author Sumant Singh ...

RIVERSIDE, Calif. – Researchers at the University of California, Riverside have identified components in pomegranate juice that both inhibit the movement of cancer cells and weaken their attraction to a chemical signal that promotes the metastasis of prostate cancer to the bone. The research could lead to new therapies for preventing cancer metastasis. Performed in the lab of Manuela Martins-Green, a professor of cell biology, the research was presented today (Dec. 12, 2010) at the 50th annual meeting of the American Society for Cell Biology taking place in Philadelphia. Prostate ...

The first two added products are seasonal and will not be available long, a 2011 calendar and a Christmas ornament. The third added product is a new figurine display called the Sunset Rider. Behind the hand-sculpted resin figure is a display with a blazing western sky, a portrait of "The Duke", and an image of John Wayne riding his horse. The border of the display is crafted to look like stone. The fourth new item is a set of four glasses, six inches high, and each glass holding ten ounces. This set has two designs, each with a portrait of John Wayne on the front, ...

Demand for newsprint in North American has declined by 50% over the past decade, and despite recent price increases the future remains bleak for producers. Strategic Analysts has released their latest white paper discussing the decline and analyzing the cost competitiveness and financial viability of AbitibiBowater and the other major producers. Springboro, OH - December 3, 2010 - Back in 2000, newsprint demand in North America was at an all time high. Daily circulation was at its record levels and the newspapers themselves were reporting record advertising revenue. ...

California-based Pizza.com has announced the addition of Shay Traynor to the company's sales staff. Ms. Traynor comes to Pizza.com from Restaurant.com, an online provider of discounted dining gift certificates that helps independent restaurants promote aspects of their business. There, she received recognition for being a top ten representative and with 15+ years of experience in the restaurant industry, was able to connect with restaurant owners and expand Restaurant.com's territory. She has previously served as a restaurant manager at The MilkyWay Restaurant and Tapas ...

As Marketing Specialist, Piracini will lead the new Machine Tools division and assist clients in determining which bearing technologies would be most suitable by taking into consideration the specifications, recommendations, maintenance strategies, fatigue life and wear resistance of the bearing in relation to the application. Piracini's clients are typically spindle repair and machinery rebuilds. They range from regional and national "mom and pop" operations to large companies. Piracini will continue to travel throughout New England several times a year visiting companies ...

Access Display Group, Inc. (ADG) has launched a new B2B e-commerce website offering light boxes in a wide range of styles, finishes and standard and custom sizes. LightBoxes4Sale.com is a niche website that focuses on a very specific sector of the display fixture market: light boxes. This narrow scope means more specialized, targeted customer care and a wider selection. Explains ADG sales and marketing director Craig Abrams, "If you're a designer or corporate buyer and you are looking for a light box, LightBoxes4Sale.com will have the perfect style and size for you." Light ...

Lisa Calkins, CEO of custom application development company Amadeus Consulting is nominated as one of the most influential women in tech for 2011. The awards are put on by Fast Company, a magazine that is at the forefront of exciting emerging technology and innovation in growing companies. The annual award is given to female power players in the technology industry who bring a unique brand thought leadership and proven success to technology companies in all sectors including: custom software development, consumer product, mobile application development, etc. The award ...

News Facts • Fishbowl Solutions, a consulting services and software development company specializing in solutions for Oracle's Universal Content Management and WebCenter products, has released Enterprise Batch Loader, a software application that provides an efficient and powerful method to check in file and data formats generated by third-party systems to Oracle Content Server. • According to AIIM (Association for Information and Image Management), 80% of an organization's information is unstructured and 90% of this remains unmanaged and continues to grow at roughly ...

For a limited time, ComputerDesksNMore.com is offering up to 60% off on select Mayline Group products. This end of year close out sale wonâEUR t last forever, and you can select from a number of different Mayline products, including bookcases, computer desks, conference tables, filing cabinets and other office and home furniture. Established in 1939, Mayline has become a market leader in office ergonomics, offering the marketâEUR s largest and diverse selection of office materials. At ComputerDesksNMore, youâEUR ll find the best selection of Mayline furniture at competitive ...