PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

The Lancet: Rate of hospitalization for severe heart attacks in China quadruples in 10 years

2014-06-24
(Press-News.org) The rate of hospitalisation for the most serious type of heart attack, ST-segment elevation myocardial infarction (STEMI), more than quadrupled in China between 2001 and 2011, according to new research published in The Lancet. The study, funded by the Chinese government, evaluates medical records, care processes, and outcomes for 13,815 hospital admissions for STEMI in 162 hospitals across China. It shows that in 2001, there were an estimated 3•7 hospital admissions for STEMI per 100,000 population, but in 2011 this rate had more than quadrupled to 15•8 hospital admissions for STEMI per 100,000 population. Despite increasing overall intensity of treatment, procedure use, and testing, no major decrease in the rate of deaths from STEMI was seen over the study period. The study cannot establish whether the increasing rate of hospitalisation observed was due to an increasing incidence of heart attacks, or improved access to hospitals. However, the study's first author, Dr Jing Li, of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing, China, notes that, "We know that this period was marked by an increasing prevalence of cardiovascular risk factors and that China has launched healthcare reform, which recently doubled annual expenditures for healthcare to improve access."* Moreover, the analysis shows that despite improving quality of care in the past decade, substantial gaps still persist. Although the use of some highly effective treatments for heart attack – such as aspirin, clopidogrel, and statins – increased over the decade studied, other therapies known to reduce mortality in STEMI patients – such as β blockers and angiotensin-converting-enzyme-inhibitors – remain very underused. Only half of ideal candidates for reperfusion therapy (critical therapy for restoring the flow of blood through blocked arteries after a heart attack) received treatment, a proportion that did not improve over time. According to the study's corresponding author, Professor Lixin Jiang, of the National Center for Cardiovascular Diseases in Beijing, China, "The growing needs for inpatient STEMI care will create pressure for Chinese hospitals to increase capacity, adequately train health-care professionals, develop infrastructure, and improve care. The striking increases in hospital admissions for STEMI noted in our study show that important improvements in capacity have been made; however, national STEMI mortality suggests that further growth will be necessary to ensure adequate access for patients with the disorder in China. Furthermore, our study underlines that access to care does not ensure the delivery of the highest-quality care; suggesting that in addition to improvements in capacity, hospitals in China must simultaneously strive to improve care."* Professor Harlan Krumholz, of Yale University School of Medicine, New Haven, USA, another of the study authors, says, "This paper sets the stage for a keen focus on achieving outstanding patient outcomes through quality improvement initiatives. Improvement begins with a willingness to evaluate rigorously the results that are currently being achieved." Writing in a linked Comment, Professor Gregg Stone, of Columbia University Medical Center, New York, USA, says that, "Before their report, little was known about this condition in a country that has almost a fifth of the world's population…Publication of these data is an important step towards improving health care in China, and should be cherished as an opportunity that could translate into saving hundreds of thousands of lives. Addressing the identified gaps in widespread access to timely reperfusion and administration of adjunctive medical therapies alone is a proven paradigm with the greatest potential to improve cardiovascular survival, especially in rural areas that have a very low density of hospitals." INFORMATION: NOTES TO EDITORS: The study was funded by the National Health and Family Planning Commission of China and the National Heart, Lung, and Blood Institute. END


ELSE PRESS RELEASES FROM THIS DATE:

How repeatable is evolutionary history?

How repeatable is evolutionary history?
2014-06-24
Writing about the weird soft-bodied fossils found in the Burgess Shale in the Canadian Rockies, paleontologist Stephen Jay Gould noted that of 25 initial body plans exhibited by the fossils, all but four were quickly eliminated. If we rewound the tape, he asked, and cast the dice once more, would the same four body plans be selected? He thought it unlikely. We can't repeat the Burgess Shale experiment, but Washington University in St. Louis biologist Ken Olsen, PhD, says there are other ways to ask whether evolution is repeatable. One is to look at related species that ...

Pygmy shrew population in Ireland threatened by invasion of greater white-toothed shrew

2014-06-24
An invading species of shrew first discovered in Ireland in the pellets of barn owls and kestrels in 2007 is spreading across the landscape at a rate of more than five kilometres a year, according to findings published in the scientific journal PLOS ONE. University College Dublin scientists who conducted the study say that the invading species, the greater white-toothed shrew (Crocidura russula) is capable of colonizing the entire island by 2050. This, they say, is leading to the disappearance of the pygmy shrew (Sorex minutus) from Ireland, one of the world's smallest ...

Women sometimes benefit more from cardiac resynchronization therapy than men

2014-06-23
Bottom Line: Cardiac resynchronization therapy plus defibrillator implantation (CRT-D) sometimes helps women with heart failure more than men, although women are less likely to receive CRT-D than men. Author: Robbert Zusterzeel, M.D., and colleagues at the Center for Devices and Radiological Health at the U.S. Food and Drug Administration, Silver Spring, Md. Background: Women are underrepresented in CRT trials for heart failure, making up only about 20 percent of participants. In selected heart failure patients CRT, or biventricular pacing, is used to help improve ...

Examining lifetime intellectual enrichment and cognitive decline in older patients

2014-06-23
Bottom Line: Higher scores that gauged education (years of school completed) and occupation (based on attributes, complexities of a job), as well as higher levels of mid/late-life cognitive activity (e.g., reading books, participating in social activities and doing computer activities at least three times per week) were linked to better cognition in older patients. Author: Prashanthi Vemuri, Ph.D., of the Mayo Clinic and Foundation, Rochester, Minn., and colleagues. Background: Previous research has linked intellectual enrichment with possible protection against ...

Intervention appears to help teen drivers get more, better practice

2014-06-23
Bottom Line: A web-based program for teen drivers appears to improve driving performance and quality supervised practice time before teens are licensed. Author: Jessica H. Mirman, Ph.D., of The Children's Hospital of Philadelphia, and colleagues. Background: During the learner phase of driver education, most states have requirements for supervisors and practice content. However, parent supervisors can vary in their interest, ability and approach to driving supervision. Inexperience is a contributing factor in car crashes involving novice drivers. How the Study ...

Mammals defend against viruses differently than invertebrates

2014-06-23
Biologists have long wondered if mammals share the elegant system used by insects, bacteria and other invertebrates to defend against viral infection. Two back-to-back studies in the journal Science last year said the answer is yes, but a study just published in Cell Reports by researchers at the Icahn School of Medicine at Mount Sinai found the opposite. In the Mount Sinai study, the results found that the defense system used by invertebrates — RNA interferences or RNAi — is not used by mammals as some had argued. RNAi are small molecules that attach to molecular scissors ...

Many ER patients test positive for HIV while in most infectious stage

2014-06-23
WASHINGTON — Human Immunodeficiency Virus (HIV) screening for emergency patients at an institution with a large number of ethnic minority, underinsured and uninsured people reveals few are HIV positive, but of those who are, nearly one-quarter are in the acute phase and more than one-quarter have infections that have already advanced to Acquired Immune Deficiency Syndrome (AIDS). The results of the study were reported online yesterday in Annals of Emergency Medicine ("Identification of Acute HIV Infection Using Fourth Generation Testing in an Opt-Out Emergency Department ...

Fatal cellular malfunction identified in Huntington's disease

2014-06-23
Researchers believe they have learned how mutations in the gene that causes Huntington's disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder. Scientists first linked the gene to the inherited disease more than 20 years ago. Huntington's disease affects five to seven people out of every 100,000. Symptoms, which typically begin in middle age, include involuntary jerking movements, disrupted coordination and cognitive problems such as dementia. Drugs cannot slow or stop the progressive decline caused by the disorder, which ...

Cocoa extract may counter specific mechanisms of Alzheimer's disease

2014-06-23
(NEW YORK – June 23) A specific preparation of cocoa-extract called Lavado may reduce damage to nerve pathways seen in Alzheimer's disease patients' brains long before they develop symptoms, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published June 20 in the Journal of Alzheimer's Disease (JAD). Specifically, the study results, using mice genetically engineered to mimic Alzheimer's disease, suggest that Lavado cocoa extract prevents the protein β-amyloid- (Aβ) from gradually forming sticky clumps in the brain, which ...

'Tom Sawyer' regulatory protein initiates gene transcription in a hit-and-run mechanism

2014-06-23
A team of genome scientists has identified a "hit-and-run" mechanism that allows regulatory proteins in the nucleus to adopt a "Tom Sawyer" behavior when it comes to the work of initiating gene activation. Their research, which appears in the Proceedings of the National Academy of Sciences, focuses on transcription factors—proteins that orchestrate the flow of genetic information from DNA to messenger RNA (mRNA). Their results show how transcription factors (TFs) activate mRNA synthesis of a gene, and leave the scene – in a model termed "hit-and-run" transcription. "Much ...

LAST 30 PRESS RELEASES:

Nutrient uptake gets to the root of roots

Aspirin not a quick fix for preventing bowel cancer

HPV vaccination provides “sustained protection” against cervical cancer

Many post-authorization studies fail to comply with public disclosure rules

GLP-1 drugs combined with healthy lifestyle habits linked with reduced cardiovascular risk among diabetes patients

Solved: New analysis of Apollo Moon samples finally settles debate about lunar magnetic field

University of Birmingham to host national computing center 

Play nicely: Children who are not friends connect better through play when given a goal

Surviving the extreme temperatures of the climate crisis calls for a revolution in home and building design

The wild can be ‘death trap’ for rescued animals

New research: Nighttime road traffic noise stresses the heart and blood vessels  

Meningococcal B vaccination does not reduce gonorrhoea, trial results show

AAO-HNSF awarded grant to advance age-friendly care in otolaryngology through national initiative

Eight years running: Newsweek names Mayo Clinic ‘World’s Best Hospital’

Coffee waste turned into clean air solution: researchers develop sustainable catalyst to remove toxic hydrogen sulfide

Scientists uncover how engineered biochar and microbes work together to boost plant-based cleanup of cadmium-polluted soils

Engineered biochar could unlock more effective and scalable solutions for soil and water pollution

Differing immune responses in infants may explain increased severity of RSV over SARS-CoV-2

The invisible hand of climate change: How extreme heat dictates who is born

Surprising culprit leads to chronic rejection of transplanted lungs, hearts

Study explains how ketogenic diets prevent seizures

New approach to qualifying nuclear reactor components rolling out this year

U.S. medical care is improving, but cost and health differ depending on disease

AI challenges lithography and provides solutions

Can AI make society less selfish?

UC Irvine researchers expose critical security vulnerability in autonomous drones

Changes in smoking status and their associations with risk of Parkinson’s, death

In football players with repeated head impacts, inflammation related to brain changes

Being an early bird, getting more physical activity linked to lower risk of ALS

The Lancet: Single daily pill shows promise as replacement for complex, multi-tablet HIV treatment regimens

[Press-News.org] The Lancet: Rate of hospitalization for severe heart attacks in China quadruples in 10 years