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Science
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Science

Participant experiences in a kidney failure care intervention in the navigate-kidney study

About The Study: The results of this study suggest that community health workers played a vital role in improving patient engagement, emotional wellbeing, and self-efficacy, suggesting their integration into dialysis care teams may enhance holistic, patient-centered care. Corresponding Author: To contact the corresponding author, Lilia Cervantes, MD, email Lilia.Cervantes@cuanschutz.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.48506) Editor’s ...

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Sotagliflozin outperforms dapagliflozin for reducing salt- sensitive hypertension and kidney injury in rats

Houston, TX (November 7, 2025) — Sodium-glucose co-transporter 2 (SGLT2) inhibitors, initially developed to treat type 2 diabetes, have significant heart- and kidney- protective effects. In the kidney, SGLT2 reabsorbs approximately 97% offiltered glucose in the S1 and S2 segments of the proximal tubule, while SGLT1reabsorbs the remainder in the S3 segment. In research conducted in rats, investigators found that dual inhibition of SGLT1 and SGLT2 more effectively reduces salt-sensitive hypertension and kidney injury than SGLT2 inhibition alone. The findings will be presented ...

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A husband’s self-esteem may protect against preterm births, study finds

A husband’s optimism and confidence may play a crucial, if often unseen, role in helping babies arrive healthy and on time. A new study from University of California Merced psychology researchers found that when married fathers reported higher levels of resilience — a quality that includes traits such as optimism, self-esteem, and perceived social support — their partners showed lower levels of inflammation during pregnancy and carried their babies longer. “This is one of the first studies to show that a father’s inner strengths, such as his optimism and ability to cope with challenges, can ripple through the family in measurable, ...

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Defunct Pennsylvania oil and gas wells may leak methane, metals into water

UNIVERSITY PARK, Pa. — In the dense forests of northwestern Pennsylvania, hundreds of thousands of retired oil and gas wells — some dating back to the mid-1800s, long before modern construction standards — dot the landscape, according to geochemists in Penn State’s College of Earth and Mineral Sciences who recently led a study in the region. Left uncapped and exposed to air and erosion, they break down, leaching harmful chemicals into the atmosphere and, the researchers reported, into the groundwater. Led by Susan L. Brantley, ...

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Science

Evaluating the potential of a sleep intervention among youth at high-risk for borderline personality disorder

Identifying ways that we can optimize Borderline Personality Disorder (BPD) treatment and prevention is an important public health priority. One area for further research is the relationship between sleep and BPD. Disrupted sleep is closely linked to key BPD features, and prior research has found a range of sleep problems among people with BPD. The Brain & Behavior Research Foundation (BBRF) will host a free webinar, “Evaluating the Potential of a Sleep Intervention Among Youth at High-Risk for Borderline Personality Disorder” on Tuesday, November 11, 2025, at 2:00 pm ET. In this webinar, Erin A. Kaufman, Ph.D., Assistant Professor in the Department ...

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Science

More children, shorter lifespan? Clear evidence from the Great Finnish Famine

Scientific theory predicts that having more offspring leads to a shorter life span, including in humans. However, despite some hundred years of research, there is no unequivocal evidence for this link. Researchers from the University of Groningen (the Netherlands), the University of Exeter (UK), and the University of Turku (Finland) have now shown that under harsh conditions, the biological cost of reproduction can indeed shorten women’s lifespans. The results were published in Science Advanceson November 7, 2025. In the 1860s, Finland experienced several harsh winters, resulting in a series of poor harvests and famine. Researcher Euan Young from the ...

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Science

More Americans are on dialysis. Could more safely wean off it?

Weaning patients with acute kidney injury (AKI) from dialysis while they are still hospitalized may save them from remaining on the treatment for the rest of their lives, according to a new study led by UC San Francisco. Instead, some patients who may have the potential to recover kidney function while hospitalized are transferred to outpatient centers with fewer specialty doctors and less intensive monitoring, where subtle signs of recovery may be overlooked. Although dialysis is needed to support patients with low kidney function, paradoxically it can delay or even prevent the ...

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Science

Heat- and cold-related mortality burden in the US from 2000 to 2020

About The Study: In this case series, nonoptimal temperatures were critical environmental contributors associated with mortality burden, with differential vulnerability by geographic location, cause of death, and demographic factors. These findings highlight the need for urgent actions against temperature-related health burdens through tailored climate and public health strategies, considering the local context and demographic profiles. Corresponding Author: To contact the corresponding ...

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Science

Research hints at the potential of pain relief with CBD

Reaching for CBD-infused lotion or oil may seem like a low-risk way to find pain relief, but little is actually known about the impact that CBD has on the nervous system. Over the past decade, the use of cannabis products for pain management has increased, in part because in 2018 Congress signed a law removing hemp from the federal Controlled Substances Act, thereby legalizing hemp-derived CBD. Today, it is most commonly found in oil form, as well as in lotions and cosmetics, and it is widely understood that CBD does not cause a ‘high’. However, what CBD does in the human body and brain is not well understood. Currently, the Food and Drug Administration ...

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Science

New alloy design could power solid-state batteries that charge faster and last longer

A team co-led by engineers at the University of California San Diego has developed a new design strategy for metal alloy negative electrodes that could significantly improve the performance and durability of next-generation solid-state batteries. The work could help advance the path toward practical, high-performance energy storage for electric vehicles. The team focused on negative electrodes made of lithium-aluminum alloy. They studied how lithium ions move through different phases of the material — a lithium-rich “beta” phase and ...

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Science

Discovery to display: FAU unveils the ‘Art of Science’ winners

Science isn’t just a pursuit of knowledge – it’s a canvas of creativity where data, design and exploration converge to reveal the unexpected beauty woven into the very fabric of discovery. Each year, Florida Atlantic University’s Division of Research celebrates creativity with its “Art of Science” contest as research transcends the lab and field to become stunning works of visual expression. The competition invites FAU faculty, students and staff to showcase their research through photography and video, strengthening connections between science, art and the broader community. The Art of Science competition also highlights ...

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Science

NIH-funded exploratory study to seek possible targets for treating alcohol use disorder

Alcohol use disorder (AUD), characterized by uncontrollable alcohol consumption due to physical and psychological dependence, affects approximately 14.1 million people in the U.S. Despite the related public health issues and associated economic costs — an estimated $249 billion annually — pharmacological treatment options for AUD have advanced only minimally since 2004. This underscores the urgent need for novel therapeutic targets. In an effort to uncover some of these potential targets, the ...

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Science

Metros cut car use in European cities, but trams fall short

[Vienna, 07.11.2025]—For his analysis, CSH researcher Rafael Prieto-Curiel examined mobility data from around 400 European cities. These data capture how daily commutes are distributed across three categories: active mobility (walking and cycling), public transport (metro, tram, bus), and (car, taxi, motorcycle, ride-hailing). “I looked at 47 cities with a metro, 46 cities with a tram but no metro, and 285 cities without both,” explains Prieto-Curiel. The data come from a larger dataset he built for earlier work, available through the ...

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Science

Single organic molecule triggers Kondo effect in molecular-scale “Kondo box”

Recently, a research group led by Prof. LI Xiangyang from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, have made a new discovery: a single organic molecule can induce the Kondo effect in a magnetic atom, challenging the long-standing belief that this quantum phenomenon requires a vast sea of metallic electrons. The research results were published in Physical Review Letters. The Kondo effect, is a quantum many-body phenomenon where conduction electrons in a metal collectively screen the magnetic moment of a localized impurity atom. It has been helping to explain strongly correlated ...

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Science

Radiative coupled evaporation cooling hydrogel for above‑ambient heat dissipation and flame retardancy

As outdoor electronic devices face increasing heat loads and fire safety risks, traditional cooling methods like fans and air conditioners fall short in energy efficiency and environmental sustainability. Now, researchers from Central South University and Brown University, led by Professor Meijie Chen, have developed a breakthrough all-in-one photonic hydrogel that combines radiative cooling (RC) and evaporative cooling (EC) for above-ambient heat dissipation and enhanced flame retardancy. Why This Hydrogel Matters Dual-Mode Cooling: Integrates RC and EC into a single material, achieving 12.0°C lower temperatures than RC films under high solar loads. Passive Water Cycle: Uses ...

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Science

Woodpeckers grunt like tennis stars when drilling

Woodpeckers pack a punch., pounding wood with extreme force and experiencing decelerations of up to 400g. Now Nicholas Antonson, Matthew Fuxjager, Stephen Ogunbiyi, Margot Champigneulle and Thomas Roberts (all at Brown University, USA) and bird song expert Franz Goller (University of Münster, Germany) reveal in Journal of Experimental Biology that drilling woodpeckers turn themselves in hammers birds by bracing their head, neck, abdomen and tail muscles to hold their bodies rigid when they pound on wood, driving each impact with the hip flexor and front neck muscles. In addition, ...

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Science

Texas Tech scientists develop novel acceleration technique for crop creation

Why This Matters: Accelerates Crop Innovation: Cuts months off the process of developing gene-edited crops, speeding up the path from gene discovery to field-ready varieties. Expands Accessibility: Reduces reliance on specialized tissue culture labs, making advanced bioengineering feasible for more research institutions and crop species. Boosts Global Food Security: Has the potential to enable faster breeding of crops with better resilience, nutrient efficiency and disease resistance. A team of plant biotechnologists ...

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Science

Worcester Polytechnic Institute to lead $5.2 million state-funded effort to build Central Massachusetts BioHub

Worcester Polytechnic Institute (WPI), in collaboration with Massachusetts Biomedical Initiatives (MBI), the City of Worcester, and more than 30 regional partners, has been awarded $5.2 million from the Commonwealth of Massachusetts to establish the BioHub, a transformative initiative designed to power the bioindustrial revolution in Central Massachusetts. The award was announced by Lt. Gov. Kim Driscoll at an event held at WPI, where she also recognized 14 other innovation and technology projects funded by the state to strengthen Massachusetts’ growing innovation economy. The BioHub will ...

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Science

China commands 47% of remote sensing research, while U.S. produces just 9%, NYU Tandon study reveals

The United States is falling far behind China in remote sensing research, according to a comprehensive new study that tracked seven decades of academic publishing and reveals a notable reversal in global technological standing. China now accounts for nearly half of all peer-reviewed journal publications in this critical field, while American output has declined to single digits. "This represents one of the most significant shifts in global technological leadership in recent history," said Debra ...

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Science

Grocery store records reveal London food deserts

A new study identified large clusters of food deserts, where residents have limited access to affordable, nutritious food, in East London—particularly Newham, Redbridge, and Barking and Dagenham—and in parts of west London such as Ealing and Brent. The findings were published November 6th in the open-access journal PLOS Complex Systems by Tayla Broadbridge of the University of Nottingham, UK, and colleagues. Poor diet and unequal access to healthy food are linked to rising rates of obesity, diabetes, and heart disease. To effectively target interventions to areas where residents face barriers ...

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Science

Hotter than your average spa bath: Extreme warming of Amazon lakes in 2023

An unprecedented heatwave and drought in 2023 turned the Amazon’s lakes into shallow simmering basins, with water temperatures soaring to temperatures above 40 degrees Celsius (ºC) in one case and water levels plunging to record lows, researchers report. The extreme temperatures had impacts ranging from isolating remote riverine communities to driving mass die-offs in fish and endangered Amazon river dolphins. The findings confirm a worrisome warming trend across the Amazon’s poorly monitored lakes and rivers and portend escalating ...

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Science

Genetic variants fine-tune grain dormancy and crop resilience in barley

New research reveals how genetic changes in the barley MKK3 gene fine-tune seed dormancy, determining whether grains stay dormant or sprout too soon. The findings offer breeders new genetic tools to balance seed dormancy and crop resilience under changing climate conditions. The rise of agriculture was driven by the intentional selection of crops with improved traits. One key trait under selection, particularly in cereal crops, is grain dormancy – the period before which a seed can germinate. In wild cereals, grain dormancy helps ensure plant survival under unpredictable conditions. ...

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Science

The enzyme that doesn’t act like one

(Vienna, 6 November 2025) Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that provides vital chemical units for the synthesis of DNA, RNA, and amino acids. When this system is disturbed - for example through genetic mutations or a lack of dietary folates - the consequences can range from developmental disorders to cancer. Now, researchers from CeMM, the Research ...

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Science

Highly efficient and compact

Lasers that emit extremely short light pulses are highly precise and are used in manufacturing, medical applications, and research. The problem: efficient short-pulse lasers require a lot of space and are expensive. Researchers at the University of Stuttgart have developed a new system in cooperation with Stuttgart Instruments GmbH. It is more than twice as efficient as previous systems, fits in the palm of a hand, and is highly versatile. The scientists describe their approach in the journal Nature. (DOI: 10.1038/s41586-025-09665-w) Eighty percent efficiency is possible “With our new system, we can achieve levels of efficiency ...

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Science

Why your daily walk might not work as well if you’re on metformin

A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise. That is the conclusion of a Rutgers-led study published in The Journal of Clinical Endocrinology & Metabolism, which found that metformin blunts critical improvements in blood vessel function, fitness and blood sugar control that normally come from working out. Since 2006, doctors have been advised to tell patients with high blood sugar to take metformin while engaging in exercise. Two proven therapies should deliver better results together, they reasoned. But Rutgers researchers ...

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