Plant Compound Targets Enzyme Linked to Beta Thalassemia in Computational Study
A computational screen of 25 compounds from Andrographis paniculata identified SRJ09 as a candidate inhibitor of HDAC2, an enzyme involved in suppressing fetal hemoglobin production. The compound passed drug-likeness filters and showed stable binding over 5-nanosecond simulations, but has not been tested in cells or animals.
Read the release