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Medicine 2024-07-31

AI creates cardiology reports for patients

An artificial intelligence program created explanations of heart test results that were in most cases accurate, relevant, and easy to understand by patients, a new study finds. The study addressed the echocardiogram (echo), which uses sound waves to create pictures of blood flowing through the heart’s chambers and valves. Echo reports include machine-generated numerical measures of function, as well as comments from the interpreting cardiologist on the heart’s size, the pressure in its vessels, and tissue thickness, which can signal the presence of disease. In the form typically generated by doctors, the reports are difficult for ...
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Medicine 2024-07-31

Nasal COVID-19 vaccine halts transmission

The lightning-fast development of COVID-19 vaccines just months after the virus appeared was a triumph of modern science and saved millions of lives. But for all the good they did in reducing illnesses and deaths, the shots were unable to end the pandemic because of one notable weakness: They couldn’t stop the spread of the virus. A new study by researchers at Washington University School of Medicine in St. Louis indicates that next-generation vaccines that target the virus’s points of entry — the nose and mouth — may be able to do what traditional shots cannot: contain the spread of respiratory infections and prevent transmission. ...
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Downwind states face disproportionate burden of air pollution
Technology 2024-07-31

Downwind states face disproportionate burden of air pollution

A recent Supreme Court decision to block a federal rule curbing interstate air pollution further complicates efforts to reduce emissions and adds to an already disproportionate burden on “downwind” states, according to researchers at the University of Notre Dame. “Toxic air pollution is really not as well known by the general public as you would hope, given its impact on human health,” said Paola Crippa, assistant professor in the Department of Civil and Environmental Engineering and Earth Sciences. ...
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Barriers designed to prevent saltwater intrusion may worsen inland flooding
Environment 2024-07-31

Barriers designed to prevent saltwater intrusion may worsen inland flooding

As Earth continues to warm, sea levels have risen at an accelerating rate – from 1.4 millimeters a year to 3.6 millimeters a year between 2000 and 2015. Flooding will inevitably worsen, particularly in low-lying coastal regions, where more than a billion people are estimated to live. Solutions are needed to protect homes, property and groundwater from flooding and the intrusion of saltwater. Seawalls and similar infrastructure are obvious options to protect against flooding. In fact, cities such as New York and San Franciso have already thrashed out potential plans with the Army Corps of Engineers that will heavily rely ...
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Medicine 2024-07-31

Vaping and smoking together increases lung cancer risk fourfold

COLUMBUS, Ohio – People who both vape and smoke are four times more likely to develop lung cancer than people who just smoke, according to new study published by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) and College of Public Health. These findings were consistent across gender and race. This is the first study to provide evidence that smoking in combination with vaping increases the risk for cancer compared to smoking alone. Researchers ...
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Social Science 2024-07-31

Scientists discover unexpected behavior in dimers of CO₂ molecules after ionization

A team of international scientists has unveiled a surprising discovery in molecular physics, revealing unexpected symmetry-breaking dynamics in ionized carbon dioxide dimers. Published in Nature Communications, the study provides new insights into the structural changes that occur when these molecular clusters are exposed to extreme ultraviolet (EUV) radiation. An international team of scientists, led by Profs. Daniel Strasser and Roi Baer from The Hebrew University of Jerusalem, has made an important discovery in molecular physics, revealing unexpected symmetry-breaking dynamics in ionized carbon dioxide dimers. Published in Nature Communications, ...
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Cracking the carb code: Researchers create new glycemic index database to improve dietary awareness
Medicine 2024-07-31

Cracking the carb code: Researchers create new glycemic index database to improve dietary awareness

Karen Della Corte, BYU nutrition and dietetics professor, recently authored a new study, published in The American Journal of Clinical Nutrition, that developed a national glycemic index (GI) and glycemic load (GL) database to offer insights into the evolving quality of carbohydrates consumed in the United States, something that hadn’t been done previously. The GI is a scale used by public health researchers to categorize the quality of the carbohydrates. High-GI foods like white flour and sugar cereals cause a “sugar rush” that can negatively impact metabolic health. ...
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Medicine 2024-07-31

Military health research reveals potential pathway to reducing youth suicide

Military-connected youth that show elevated risk for suicidal ideation and suicide plans exhibit lower rates of gun-carrying, according to new research from emergency medicine faculty at the University of Colorado School of Medicine. The analysis, published in JAMA Network Open July 31 by members of the CU Center for Combat Medicine and Battlefield (COMBAT) Researchand Firearm Injury Prevention Initiative (FIPI), offers promising insight for potentially reducing gun-carrying among youths with recent suicidal ideation or plans. Researchers are also interested in how relevant strategies in military communities ...
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Medicine 2024-07-31

Cannabinoid CBG reduces anxiety and stress in first human clinical trial

PULLMAN, Wash. — A lesser-known cannabinoid that is gaining in popularity Cannabigerol (CBG) effectively reduced anxiety in a clinical trial without the intoxication typically associated with whole plant cannabis. It may even have some memory enhancing effects, according to a new study in Scientific Reports. For the study, Carrie Cuttler, an associate professor of psychology at Washington State University, and colleagues conducted the first human clinical trial investigating the acute effects of CBG on anxiety, stress and mood. The research revealed that 20 mg of hemp-derived CBG significantly reduced feelings of anxiety at 20, ...
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Medicine 2024-07-31

University hospitals nationally recognized for high-quality stroke care

CLEVELAND — University Hospitals (UH) has received numerous American Heart Association Get With The Guidelines® - Stroke quality achievement awards for ensuring stroke patients receive the most appropriate treatment according to nationally recognized, research-based guidelines, ultimately leading to more lives saved and reduced disability. Stroke is the No. 5 cause of death and a leading cause of disability in the U.S. A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain is either blocked by a clot or bursts. When that happens, part of the brain cannot get the blood and oxygen it needs, so ...
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Science 2024-07-31

Humans are born to run

The 2024 Summer Olympics are in full swing. One of the marquee events is of course the marathon, a grueling test of fitness and athleticism.  When it comes to endurance running, humans are among the very top mammals in their athletic prowess. While we may not be the best sprinters in the animal kingdom, we can run steadily for long distances, even in hot weather. Our locomotor muscles are dominated by slow-twitch, fatigue-resistant fibers and our unique ability to sweat allows our bodies to effectively dissipate heat. Humans are so good at endurance running, it seems we were born to do it. But why? A theory of endurance In ...
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Medicine 2024-07-31

Medicaid enrollees struggle to find psychiatric care

Many people enrolled in Medicaid who require psychiatric care have difficulty accessing clinicians in a timely manner despite the higher need in this population, according to a study by researchers at Weill Cornell Medicine. The results published July 31 in JAMA found that few psychiatrists and other mental health professionals who are listed as accepting new patients enrolled in Medicaid are actually reachable and have appointments available. In cases when appointments could be made, wait times sometimes extended up to six months. The research was conducted by first author Dr. Diksha Brahmbhatt (M.D. ’24), who is now a resident physician at Brigham and Women’s ...
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Smithsonian scientists devise method to secure Earth’s biodiversity on the moon
Environment 2024-07-31

Smithsonian scientists devise method to secure Earth’s biodiversity on the moon

New research led by scientists at the Smithsonian proposes a plan to safeguard Earth’s imperiled biodiversity by cryogenically preserving biological material on the moon. The moon’s permanently shadowed craters are cold enough for cryogenic preservation without the need for electricity or liquid nitrogen, according to the researchers.  The paper, published today in BioScience and written in collaboration with researchers from the Smithsonian’s National Zoo and Conservation ...
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Revolutionary x-ray-sensitizers could transform cancer treatment with low-dose radiation therapy
Medicine 2024-07-31

Revolutionary x-ray-sensitizers could transform cancer treatment with low-dose radiation therapy

Researchers at Xiamen University have made a significant advancement in cancer treatment by developing a novel class of X-ray-sensitizers (XSs) that could revolutionize radiotherapy. Published in Engineering, their groundbreaking study highlights how specific organic pharmaceutical drug intermediates, derived from thioxanthone (TX), can be activated by low-dose X-rays to efficiently generate singlet oxygen for targeted cancer therapy. Traditional radiotherapy, a cornerstone in cancer treatment, often involves high doses of radiation (typically over 50 Gy), which can lead ...
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Technology 2024-07-31

ATMs and other digital self-serve devices fail to meet accessibility needs

Most self-service interactive devices — kiosks, ATMs and other digital interfaces — don't measure up to the accessibility needs of Canadians who report to have a disability, a new study has found.  In partnership with the CSA Group (Canadian Standards Association), University of Waterloo researchers interviewed people with lived experiences of disability and received an overwhelming consensus that most self-serve devices have little to no accessibility features or they have trouble finding ...
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Environment 2024-07-31

520-million-year-old worm fossil solves mystery of how modern insects, spiders and crabs evolved

A new study led by researchers at Durham University have uncovered an incredibly rare and detailed fossil, named Youti yuanshi, that gives a peek inside one of the earliest ancestors of modern insects, spiders, crabs and centipedes.   This fossil dates back over 520 million years to the Cambrian period, when the major animal groups we know today were first evolving.   This fossil belongs to a group called the euarthropods, which includes modern insects, spiders and crabs. What makes this fossil so special ...
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A new use for propofol in treating epilepsy?
Science 2024-07-31

A new use for propofol in treating epilepsy?

The general anesthetic propofol may hold the keys to developing new treatment strategies for epilepsy and other neurological disorders, according to a study led by researchers at Weill Cornell Medicine and Sweden’s Linköping University. In their study, published July 31 in Nature, the researchers determined the high-resolution structural details of how propofol inhibits the activity of HCN1, an ion channel protein found on many types of neurons. Drug developers consider inhibiting HCN1 a promising strategy for treating neurologic disorders including epilepsy and chronic pain. The researchers also found, to their surprise, that when HCN1 contains ...
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Medicine 2024-07-31

Trust in physicians and hospitals during the COVID-19 pandemic in a 50-state survey of US adults

About The Study: The results of this survey study of U.S. adults suggest that trust in physicians and hospitals decreased during the COVID-19 pandemic. As lower levels of trust were associated with lesser likelihood of pursuing vaccination, restoring trust may represent a public health imperative.  Corresponding Author: To contact the corresponding author, Roy H. Perlis, MD, MSc, email rperlis@mgh.harvard.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.24984) Editor’s ...
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Science 2024-07-31

State policies regulating firearms and changes in firearm mortality

About The Study: In this comparative effectiveness study of state firearm policies, the joint effect estimates of combinations of firearm laws were calculated, showing that restrictive firearm policies were associated with substantial reductions in firearm mortality. Although policymakers would benefit from knowing the effects of individual policies, the estimated changes in firearm mortality following implementation of individual policies were often small and uncertain.  Corresponding Author: To contact the corresponding ...
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Science 2024-07-31

City-level sugar-sweetened beverage taxes and youth body mass index percentile

About The Study: Sugar-sweetened beverage excise taxes were associated with lower body mass index percentile among youth in this cohort study. Policymakers should consider implementing sugar-sweetened beverage excise taxes to prevent or reduce youth overweight and obesity and, ultimately, chronic disease, particularly among children younger than 12 years.  Corresponding Author: To contact the corresponding author, Deborah Rohm Young, PhD, email deborah.r.young@kp.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.24822) Editor’s ...
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Impact of neighborhood resources on resilience after trauma
Science 2024-07-31

Impact of neighborhood resources on resilience after trauma

E. Kate Webb, PhD, a research fellow at McLean Hospital who works in the Neurobiology of Fear Laboratory and Neurobiology of Affective and Traumatic Experiences Laboratory, led an investigation into whether individual resources and neighborhood resources, like greenspace, might impact neurobiology and the trajectory of posttraumatic stress disorder (PTSD) symptoms. Her research was published July 31st in JAMA Psychiatry. What led you to examine the link between neighborhood characteristics and PTSD? About 46 million people experience ...
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Medicine 2024-07-31

Study finds nearly half of top cancer centers required universal masking during last winter’s COVID-19 surge

Nearly half of the nation’s National Cancer Institute (NCI)-designated cancer centers required universal masking in key clinical areas during the winter 2023-2024 COVID-19 surge, according to a study by Tulane University researchers. Overall, 41.8% of these 67 centers required some universal masking, according to the study, which published in JAMA Network Open. Further, 12 NCI-designated centers (18%) required universal masking in all areas. Masking policies were even more common in northeastern states and in centers with longer NCI designation, more funding and higher care rankings. Those with cancer face higher risks from COVID-19 ...
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This protein does “The Twist”
Medicine 2024-07-31

This protein does “The Twist”

Proteins are constantly performing a kind of dance. They move and contort their bodies to fulfill specific functions inside our bodies. The NMDAR protein executes an especially hard dance routine in our brains. One wrong step can lead to a range of neurological disorders. NMDAR binds to the neurotransmitter, glutamate, and another compound, glycine. These bindings control NMDAR’s dance steps. When their routine is over, the NMDAR opens. This open ion channel generates electrical signals critical for cognitive functions like memory. The problem is that scientists couldn’t figure out the last step in NMDAR’s routine—until ...
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Gut microbes implicated in bladder cancer
Medicine 2024-07-31

Gut microbes implicated in bladder cancer

At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world. This includes – as shown in a new study by EMBL researchers and collaborators at the University of Split, Croatia – the way the body responds to carcinogens and develops cancer.  Carcinogens are chemicals that can cause ordinary cells to transform into cancer ...
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Medicine 2024-07-31

Trust in physicians and hospitals declined over the course of the COVID-19 pandemic

BOSTON– A cross-representative survey of adults in the United States showed decreasing levels of trust in physicians and hospitals during the COVID-19 pandemic—and the lower the trust, the less likely an individual was to get vaccinated against SARS-CoV-2 or influenza. The findings come from a survey study of more than 400,000 U.S. adults published in JAMA Network Open by a team co-led by investigators at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system. “Trust in ...
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