What is the structure of a particular molecule? And how do molecules interact with each other? Researchers interested in those questions frequently use nuclear magnetic resonance (NMR) spectroscopy to find answers. In NMR, a powerful external magnetic field is employed to align the spins of atomic nuclei, which are then induced to rotate by an oscillating weak magnetic field generated by coils. A change in voltage as a result can be converted to measurable frequencies. Based on this, researchers can identify the molecular structures while also revealing ...

A new report shows that research projects at The University of Texas at Arlington contributed one quarter of a billion dollars—$226.4 million, to be exact—to the national economy through 797 vendor contracts and subcontracts between 2018 and 2022. Of those contracts, 111 were from small businesses and 87 from minority- or woman-owned businesses. “Research coming from UT Arlington faculty and students not only helps solve some of society’s most vexing problems, but it is also an important economic driver for business development,” said Kate C. Miller, vice president for research and innovation at UTA. “This report makes clear that UTA research ...

The great promise of bacteriophages is that they naturally destroy bacteria, often in situations where antibiotics fail. Until now, though, there has been no way to access them quickly and efficiently, especially in emergency cases of antibiotic resistant infections. Researchers at McMaster University, working with a colleague from Université Laval, have developed a simple new way to store, identify, and share phages, making them more accessible to patients who need them. “Bacteriophages ...

HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.  Recent developments at MD Anderson offer insights into mechanisms regulating metabolic programming and cellular senescence, ...

Ann Arbor, July 11, 2024 – Investigators analyzing the potential cognitive effects of antidiabetic medications in records of more than 1.5 million patients with type 2 diabetes mellitus (T2DM) found risks of dementia and Alzheimer’s disease (AD) were significantly lower in patients treated with metformin and sodium glucose co-transporter-2 inhibitors (SGLT-2i) compared to other antidiabetic drugs. Their results appear in the American Journal of Preventive Medicine, published by Elsevier. T2DM has become ...

An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth—the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth’s genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because ...

An increased amount of thick sea ice flowing south from the Arctic Ocean shortened the ice-free shipping season in several parts of the Northwest Passage between 2007 and 2021, according to an analysis in Communications Earth & Environment. The authors suggest this could mean the Northwest Passage is unlikely to become a viable alternative to traditional shipping routes, despite previous hopes that it may become viable due to global warming. The Northwest Passage (NWP) is a commercial shipping route connecting the Atlantic and Pacific Oceans that runs through the Arctic Circle north of North America. Through the Canadian ...

DURHAM, N.C. – Certain state gun laws are associated with decreased suicide rates for children under age 18, but the laws have little influence on homicide rates, according to a study from Duke Health researchers examining the relationship between gun laws and child deaths.   Since 2020, firearms rank as the leading cause of death among U.S. children ages 1-18, raising the need for research to help guide prevention efforts.   “Our analysis of suicide and homicide mortality data from ...

About The Study: Substance use treatment facilities reported significant gaps in provision of effective treatments for opioid use disorder (OUD). More than one-third of facilities did not offer medications for OUD (MOUD) and less than half offered multiple MOUD types, limiting MOUD treatment options for patients and clinicians.   Corresponding Author: To contact the corresponding author, Tae Woo Park, M.D., M.Sc., email parkt4@upmc.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jama.2024.11913) Editor’s ...

About The Study: In this cross-sectional study of U.S. children, nicotine absorption was much lower in children who were exposed to secondhand vapor versus secondhand smoke, but higher than in those exposed to neither. These findings suggest that switching from smoking to vaping indoors may substantially reduce, but not eliminate, children’s secondhand exposure to nicotine and other noxious substances.  Corresponding Author: To contact the corresponding author, Harry Tattan-Birch, Ph.D., email h.tattan-birch@ucl.ac.uk. To ...

About The Study: This comparative effectiveness research study demonstrated that self-fit over-the-counter hearing aids can offer comparable long-term benefits to audiologist-fit hearing aids for individuals with mild to moderate hearing loss.  Corresponding Author: To contact the corresponding author, Karina C. De Sousa, Ph.D., email karina.swanepoel@up.ac.za. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaoto.2024.1825) Editor’s Note: Please ...

Children exposed to vaping indoors absorb less than one seventh the amount of nicotine as children who are exposed to indoor smoking, but more than those exposed to neither, according to a new study led by UCL researchers. The study, published in JAMA Network Open and funded by Cancer Research UK, looked at blood tests and survey data for 1,777 children aged three to 11 in the United States. The researchers said that second-hand exposure to harmful substances in e-cigarettes would likely be much lower still, as e-cigarettes deliver similar levels of nicotine to tobacco but contain only a fraction of the toxicants and ...

– By William Ferguson When it comes to figuring out why electric aircraft batteries lose power over time, one typically wouldn’t think to turn to a decades-old approach biologists use to study the structure and function of components in living organisms. However, it turns out that omics, a field that helped scientists unravel the secrets of the human genome, could also soon play a key role in making carbon-free air travel a reality. In a new study in the journal Joule, a team of researchers led ...

Images A battery component innovation could help keep power delivery high when electric aircraft land with low charge, according to a study led by Lawrence Berkeley National Laboratory with expertise from the University of Michigan.  The research provides a solution to a problem identified in 2018 in a study led by Venkat Viswanathan, a professor of aerospace engineering at U-M and a coauthor of the new work published in Joule.  "Both takeoff and landing require high power, and landing is more challenging because you’re not fully charged," Viswanathan said. "To get high power you ...

Tokyo Medical and Dental University (TMDU) researchers have discovered that patients with 18q deletion syndrome can experience both cellular and humoral immunodeficiency Tokyo, Japan – Chromosome 18q deletion  (18q del) syndromeis a rare genetic condition disorder, affecting approximately 1 in 40,000 to 55,000 individuals, caused by the deletion of genetic material on the long arm of chromosome 18. This genetic anomaly disrupts normal growth and development, and critically, can impair the immune system's functionality. Patients with 18q del syndrome often exhibit humoral immunodeficiency or a common ...

On June 30, 2024, SciOpen 2.0 was officially launched. Developed by Tsinghua University Press, SciOpen initially made its debut in June 2022 as an international digital publishing platform for STM journals. After two years of global operation and continuous iterative upgrades, SciOpen 2.0 has fully embraced the best practices of mainstream publishing models. SciOpen has completed a comprehensive upgrade of its interactive system design and has integrated advanced large-model AI reading capabilities, marking a significant leap forward in its functionality.   These updates steer SciOpen towards ...

(Toronto, July 11, 2024) JMIR Publications invites submissions to a new theme issue titled “Artificial Intelligence in Oncology” in its premier open access journal JMIR Bioinformatics and Biotechnology indexed in PubMed Central and PubMed, SCOPUS, Sherpa/Romeo, DOAJ and EBSCO/EBSCO Essentials. Artificial intelligence (AI) has the potential to revolutionize oncology by enhancing diagnostic accuracy, personalizing treatment plans, predicting patient outcomes, and accelerating drug discovery. Researchers, clinicians, and industry experts are invited ...

A new study led by researchers at the American Cancer Society (ACS) finds four in 10 cancer cases and about one-half of all cancer deaths in adults 30 years old and older in the United States (or 713,340 cancer cases and 262,120 cancer deaths in 2019) could be attributed to modifiable risk factors, including cigarette smoking, excess body weight, alcohol consumption, physical inactivity, diet, and infections. Cigarette smoking was by far the leading risk factor, contributing to nearly 20% of all cancer cases and 30% of all cancer deaths. The findings are ...

The study by researchers from the French national public health institute aimed to identify priority pathogens that could be suitable for wastewater surveillance (WWS) during the Paris 2024 Olympic and Paralympic Games taking place from 26 July to 11 August and 28 August to 8 September, respectively. The pathogens were evaluated using a Delphi method which integrated evidence from peer-reviewed publications and expert opinion. WWS has become more prominent due to its role during the COVID-19 pandemic. As a non-intrusive, cost-effective surveillance tool, WWS offers ...

Dense E.coli bacteria have several similar qualities to colloidal glass, according to new research at the University of Tokyo. Colloids are substances made up of small particles suspended within a fluid, like ink for example. When these particles become higher in density and more packed together, they form a “glassy state.” When researchers multiplied E.coli bacteria within a confined area, they found that they exhibited similar characteristics. More surprisingly, they also showed some other unique properties not typically found in glass-state materials. This study contributes to our understanding of glassy “active matter,” a relatively new field of ...

Weill Cornell Medicine has received $4.2 million to study how the immune system in some people infected with HIV can keep the virus under control, which could lead to novel therapeutic strategies for thwarting or eliminating HIV. Dr. Brad Jones, associate professor of immunology in medicine in the Division of Infectious Diseases at Weill Cornell Medicine, was awarded a MERIT grant from the National Institute for Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH). The “Method for Extending Research in Time” (MERIT) grant provides ...

According to Science Alert, neuroscientists from Johns Hopkins University have recently discovered a new treatment for Parkinson's disease using an FDA-approved cancer drug. A recent study published in Neuroscience Bulletin reveals the genetic cause of Parkinson's disease. The study discovered that a mutation in the Cysteinyl-tRNA synthetase (CARS) gene (c.2384A>T; p.Glu795Val; E795V) is responsible, offering a new path for prevention and control of the disease. This research was conducted by a team led by Zhang Jianguo, including researcher ...

People tend to become less narcissistic as they age from childhood through older adulthood, according to a study published by the American Psychological Association. However, differences among individuals remain stable over time -- people who are more narcissistic than their peers as children tend to remain that way as adults, the study found. “These findings have important implications given that high levels of narcissism influence people’s lives in many ways -- both the lives of the narcissistic individuals themselves and, maybe even more, the lives of their families and friends,” said lead author Ulrich Orth, PhD, of the University of Bern in Switzerland. The ...

A group of scientists have released a landmark report on glacial geoengineering—an emerging field studying whether technology could halt the melting of glaciers and ice sheets as climate change progresses. The white paper represents the first public efforts by glaciologists to assess possible technological interventions that could help address catastrophic sea-level rise scenarios. While it does not endorse any specific interventions, it calls for a “major initiative” in the next decades to research which, if any, interventions could and should be ...

New York, NY (July 11, 2024) – The Icahn School of Medicine at Mount Sinai is embarking on biomedical research aiming to set new standard-of-care protocols for treating alopecia areata and atopic dermatitis in people with Down syndrome, or trisomy 21. Emma Guttman-Yassky, MD, PhD, the Waldman Professor and Chair of Dermatology at Icahn Mount Sinai, has been awarded more than $4 million for a five-year National Institutes of Health (NIH) R61/R33 grant to evaluate the long-term safety, efficacy, and mechanisms of medications known as JAK inhibitors in patients with Down syndrome. The medications have been approved ...