Transporting precious cargo using the body’s own delivery system
Each cell in the body has its own unique delivery system that scientists are working on harnessing to move revolutionary biological drugs — molecules like proteins, RNA and combinations of the two — to specific diseased parts of the body.
A new study from Northwestern University hijacked the transit system and sent tiny, virus-sized containers to effectively deliver an engineered protein to its target cell and trigger a change in the cell’s gene expression. The success came from encouraging engineered proteins to move toward a specific cell membrane structure that the researchers found increased a protein’s likelihood of latching onto the container.
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