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New study gives clues on why exercise helps with inflammation

2023-06-15
TORONTO, CANADA, June 15, 2023 - Researchers have long known that moderate exercise has a beneficial impact on the body’s response to inflammation, but what’s been less understood is why. New research coming out of York University done on a mouse model suggests that the answers may lie at the production level of macrophages — white blood cells responsible for killing off infections, healing injury and otherwise acting as first responders in the body.   “Much like if you train your muscles through ...

Climate change likely led to violence in early Andean populations

2023-06-15
Climate change in current times has created problems for humans such as wildfires and reduced growing seasons for staple crops, spilling over into economic effects. Many researchers predict, and have observed in published literature, an increase in interpersonal violence and homicides when temperatures increase. Violence during climatic change has evidence in history. University of California, Davis, researchers said they have have found a pattern of increased violence during climatic change in the south central Andes between A.D. 470 and 1500. During that time, which includes the Medieval Climatic ...

Carbon mitigation payments can make bioenergy crops more appealing for farmers

Carbon mitigation payments can make bioenergy crops more appealing for farmers
2023-06-15
URBANA, Ill. — Bioenergy crops such as miscanthus and switchgrass provide several environmental benefits, but low returns and profit risks are barriers for investment by farmers. A new study from the University of Illinois Urbana-Champaign shows that carbon mitigation payments could increase net returns and reduce income risk, potentially enticing more farmers to grow these crops. “We were interested in looking at the returns to farmers and the risks to farm income of adopting bioenergy crops compared to conventional corn and soybean crops. We ...

Grant awarded to investigate antifungal therapies in Crohn’s patients

2023-06-15
Dr. Iliyan D. Iliev, an associate professor of immunology in medicine in the Division of Gastroenterology and Hepatology, co-director of the Microbiome Core and a member of the Jill Roberts Institute for Research in Inflammatory Bowel Disease (IBD) at Weill Cornell Medicine, is the lead investigator on a grant to Weill Cornell Medicine from The Leona M. and Harry B. Helmsley Charitable Trust to target pathogenic fungi in patients with Crohn’s disease. Dr. Iliev teamed up with Dr. Randy Longman, ...

FAMU-FSU College of Engineering researchers want drivers to see clearly on the road

FAMU-FSU College of Engineering researchers want drivers to see clearly on the road
2023-06-15
Every year, sun glare contributes to around 3,000 crashes in the United States. FAMU-FSU College of Engineering researchers are helping to mitigate this problem by examining what drivers are likely to do when faced with sun glare. Their work was published in Transportation Research Record. “We want drivers to be safer on the road,” said study co-author Eren Ozguven, director of the Resilient Infrastructure and Disaster Response Center. “At certain times of day, the sun can be blinding, so as scientists and engineers, we want to find solutions.” The first step is to understand where problems are most likely to occur. ...

Scientists discover how Golden staph hides and thrives in human cells using state-of-the-art research tool

Scientists discover how Golden staph hides and thrives in human cells using state-of-the-art research tool
2023-06-15
Nearly one in three people globally unknowingly carries Golden staph, or Staphylococcus aureus, in their nose or on their skin. While the bacterium is harmless to most, it can lead to serious infection and even death if it enters the bloodstream through a cut, surgical wound or catheter. The major breakthrough, led by the University of Melbourne’s Dr Abdou Hachani, a Senior Researcher at the Peter Doherty Institute for Infection and Immunity (Doherty Institute), published in the online medical journal eLife, was made possible by a new state-of-the-art ...

Massive underwater plateau near Solomon Islands is younger and its eruption was more protracted than previously thought, research suggests

2023-06-15
CORVALLIS, Ore. – The Ontong Java Plateau, a volcanically-formed underwater plateau located in the Pacific Ocean north of the Solomon Islands, is younger and its eruption was more protracted than previously thought, new research led by Oregon State University suggests. The findings, just published in Science, also cast doubt on long-held assumptions that the formation of the plateau, which is roughly the size of Alaska, was the cause of a global deposit of black shale throughout the world’s oceans. “This type of shale is formed when there is very limited oxygen in the ocean. This layer was formed about 120 million years ago and can be found preserved ...

Prenatal exposure to phthalates may impact future fertility differently in males and females, animal study finds

2023-06-15
Prenatal exposure to chemicals called phthalates, which are used in hundreds of products, may lead to hormonal changes in females that could affect their future fertility, suggests a study in mice being presented Thursday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill. The study found female mouse embryos exposed to phthalates during gestation had lower testosterone levels than those not exposed to the chemicals. Immediately after birth, female mice exposed to phthalates during gestation had lower levels of the hormone estradiol than those not exposed. “These changes in hormone levels ...

Limiting opioids during surgery may lead to more postoperative pain and opioid use for patients

2023-06-15
BOSTON – Because of the opioid crisis, physicians are less likely to administer opioids to help manage patients’ pain, even in the operating room. A recent analysis in JAMA Surgery that was conducted by investigators at Massachusetts General Hospital (MGH), a founding member of Mass General Brigham, indicates that overly restricting use of opioids during surgery may be doing more harm than good. For the study, researchers analyzed information on 61,249 adults who had surgery at MGH from 2016–2020. Patients administered more of the ...

HaoSheng Sun named a Freeman Hrabowski scholar by the Howard Hughes Medical Institute

HaoSheng Sun named a Freeman Hrabowski scholar by the Howard Hughes Medical Institute
2023-06-15
BIRMINGHAM, Ala. – HaoSheng Sun, Ph.D., assistant professor in the University of Alabama at Birmingham Department of Cell, Developmental and Integrative Biology, has been named to the inaugural class of Freeman Hrabowski scholars by the Howard Hughes Medical Institute. The 31 new scholars from 22 U.S. institutions are all outstanding early career faculty in science who have the potential to become leaders in their research fields, as well as advance diversity, equity and inclusion through their mentorship and understanding of the experiences of trainees from races and ethnicities that are underrepresented in U.S. ...

Low food security linked to metabolic syndrome in reproductive-aged Latinx females

2023-06-15
CHICAGO—Not having reliable access to food has a significant relationship with metabolic syndrome, a condition that increases risk for diseases such as diabetes and heart disease, in Latinx females of reproductive age, according to a study presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill. “Because of the significant association identified between low food security and metabolic syndrome in reproductive-aged Latinx females, there is potential to reduce cardiovascular, metabolic and reproductive adverse outcomes through improved ...

BMI alone may not be a sufficient indicator of metabolic health

2023-06-15
CHICAGO—Body mass index (BMI) is not a complete measure of metabolic health, and a high proportion of U.S. adults with normal BMI still have obesity, according to research being presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill. The latest research highlights the importance of including what percentage of the body is fat, muscle, bone, and water, and how much fat is in the abdomen vs. the thighs to fully understand drivers for cardio-metabolic disease. “We show that there are racial/ethnic differences in body ...

Some breast cancer treatments may limit effectiveness of weight loss medications

2023-06-15
Breast cancer medications, called aromatase inhibitors, may lessen the effect of weight loss drugs, according to a new study being presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill. The study found that weight loss medications are less effective in breast cancer survivors who are treated with aromatase inhibitors, compared with women without a history of breast cancer who are not taking aromatase inhibitors. Aromatase inhibitors are used to treat some types of breast cancer or to keep it from coming back. They may also be used to help prevent breast cancer in some women who are ...

CGM alarms often not set to alert children with diabetes to harmful blood glucose fluctuations

2023-06-15
Children and teenagers who use continuous glucose monitors (CGM) to manage diabetes often fail to use the appropriate alarm settings to alert to dangerously low or harmful high blood sugar levels, according to a study being presented Thursday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill. This variability makes the monitors less useful in tracking glucose levels. Children with diabetes employ a large range of CGM alarm settings and cutoffs, many of which differ significantly from recommended values. ...

Astrocyte processing of serotonin regulates olfactory perception

2023-06-15
To enjoy the scent of morning coffee and freshly baked cookies or to perceive the warning smell of something burning, the brain needs two types of cells, neurons and astrocytes, to work closely with each other. Research has shown a great deal of the changes that occur in neurons during olfactory, or smell, perception, but what are the astrocyte responses and how they contribute to the sensory experience remains unclear. Researchers at Baylor College of Medicine and collaborating institutions report in the journal Science the responses of astrocytes to olfactory stimulation, revealing ...

Close up on aging reveals how different cell types in the body age at different pace

2023-06-15
As the body ages, organ function progressively declines and the risk for a wide range of diseases, including cardiovascular disease, cancer and neurodegenerative diseases, increases. Understanding how the body ages is an intense area of research as it will potentially illuminate ways to promote healthy aging. Researchers at Baylor College of Medicine, Chan Zuckerberg Biohub San Francisco, Genentech, Inc. and collaborating institutions are breaking a path in that direction. They report in the journal Science, the first Aging Fly Cell Atlas (AFCA), ...

A new path for quantum physics to control chemical reactions

A new path for quantum physics to control chemical reactions
2023-06-15
Controlling chemical reactions to generate new products is one of the biggest challenges in chemistry. Developments in this area impact industry, for example, by reducing the waste generated in the manufacture of construction materials or by improving the production of catalysts to accelerate chemical reactions. For this reason, in the field of polariton chemistry - which uses tools of chemistry and quantum optics - in the last ten years different laboratories around the world have developed experiments in optical cavities to manipulate the chemical reactivity of molecules at room temperature, ...

Light Pollution Special Issue

2023-06-15
Light pollution is increasing around the globe, both in its intensity and geographic extent. Researchers are documenting its impact on ecosystems, human health, and culture, while warning that the wasted light has financial costs, environmental impacts, and is responsible for substantial greenhouse gas emissions. In a special issue of Science, five papers discuss the growing adverse impacts of light pollution, along with the regulatory and technological solutions that could help mitigate its effects. Artificial ...

Aging fly atlas reveals cellular-level view of aging over the life of a model organism

2023-06-15
Tzu-Chiao Lu, Maria Brbic and colleagues have completed the Aging Fly Cell Atlas, a single-nucleus transcriptome map of the Drosophila melanogaster fly as it ages. Aging is known to be a risk factor for many diseases across many animals including humans, but understanding how the process affects cell composition and different cell types is still mostly unknown, making the new atlas a valuable reference in further studies. Lu et al. used single-nucleus RNA sequencing to generate the Fly Cell Atlas that profiles ...

Massive eruption of Ontong Java Plateau is younger than previously thought

2023-06-15
New high-precision argon isotope dating of the Ontong Java Plateau indicates that it is 10 million years younger than previously thought, according to Peter Davidson and colleagues. The Ontong Java Plateau is part of a massive underwater volcanic eruption – possibly the largest in Earth’s history – that took place in the Cretaceous Period in the equatorial western Pacific Ocean. This huge igneous emplacement has been proposed as the cause of Ocean Anoxic Event (OAE) 1a – a short period of severely reduced oxygen in the ocean - but the new dates for the eruption suggest it happened after OAE 1a. Some researchers ...

Cleaner air with a cold catalytic converter

2023-06-15
The so-called three-way catalytic converter in the exhaust system of a car consists of expensive materials and only works correctly when the exhaust gases have a temperature that is several hundred degrees Celsius. As a result, when you start your car, or when you drive a hybrid car in which the petrol engine and electric motor alternate between driving the powertrain, the gases leaving the exhaust still contain toxic carbon monoxide. In a new Science article, scientists led by Emiel Hensen now show that by modifying the carrier material of the catalyst, it is possible to almost completely convert toxic carbon monoxide into carbon dioxide gas even at room temperature. Noble ...

Illusions are in the eye, not the mind

Illusions are in the eye, not the mind
2023-06-15
Numerous visual illusions are caused by limits in the way our eyes and visual neurones work – rather than more complex psychological processes, new research shows. Researchers examined illusions in which an object’s surroundings affect the way we see its colour or pattern. Scientists and philosophers have long debated whether these illusions are caused by neural processing in the eye and low-level visual centres in the brain, or involve higher-level mental processes such as context and prior knowledge. In the new study Dr Jolyon Troscianko, from the University of Exeter, co-developed a model that suggests simple limits to neural responses – not deeper ...

If art is how we express our humanity, where does AI fit in?

If art is how we express our humanity, where does AI fit in?
2023-06-15
The rapid advance of artificial intelligence has generated a lot of buzz, with some predicting it will lead to an idyllic utopia and others warning it will bring the end of humanity. But speculation about where AI technology is going, while important, can also drown out important conversations about how we should be handling the AI technologies available today. One such technology is generative AI, which can create content including text, images, audio, and video. Popular generative AIs like the chatbot ...

NCCN convenes policy summit assessing impact of geography on cancer outcomes, examining rural and urban divide

NCCN convenes policy summit assessing impact of geography on cancer outcomes, examining rural and urban divide
2023-06-15
WASHINGTON, D.C. [June 15, 2023] — Today, the National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers—convened a policy summit to examine how geography impacts cancer outcomes. NCCN Chief Executive Officer, Robert W. Carlson, MD, opened the event with a focus on equity. “NCCN’s work is guided by the idea that where you live should not impact whether you live,” said Dr. Carlson. “NCCN Guidelines are one free resource to make sure everyone, everywhere, has access to cancer care based on the latest evidence ...

Shaping the future of medicine: Redox Science takes center stage at the International Conference of Redox Medicine Society in Paris

Shaping the future of medicine: Redox Science takes center stage at the International Conference of Redox Medicine Society in Paris
2023-06-15
Paris is set to host the highly anticipated 25th International Conference of the Redox Medicine Society, where global leaders and experts from the field will converge to unveil groundbreaking advancements and shed light on the future of Redox Medicine. Taking place from June 21 to June 23, the conference will feature over 61 dynamic communications, including major presentations, short talks, and poster sessions, showcasing the latest research and discoveries in the field of redox reactions, oxidative stress, and their profound ...
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