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Education program tackles race-based cancer health disparities

Education program tackles race-based cancer health disparities
2023-08-10
HOUSTON – (Aug. 10, 2023) Rice University chemist Carolyn Nichol has won a competitive Science Education Partnership Award (SEPA) from the National Institutes of Health to address race-based cancer health disparities by increasing underrepresented minority student populations’ engagement and participation in biosciences education. The 5-year, $1,038,544 award will support Nichol’s Cancer Health Activism Network for Greater Equity (CHANGE) project in bringing together cutting-edge cancer research with insight on race-based healthcare disparities from the social sciences in a series of transformative high school biology lessons aligned with both ...

Font size can 'nudge' customers toward healthier food choices

2023-08-10
PULLMAN, Wash. -- Restaurants can persuade patrons to choose healthier foods by adjusting the font size of numbers attached to nutritional information on menus, according to a study headed by a Washington State University researcher. Lead researcher Ruiying Cai, an assistant professor in the WSU School of Hospitality Business Management, said U.S. restaurants with more than 20 locations are already required to show the calorie content of food on their menus. By representing these values incongruously — using physically larger numbers on the page when they’re attached to ...

Researchers unlock mystery of cartilage regeneration in lizards

Researchers unlock mystery of cartilage regeneration in lizards
2023-08-10
A team of researchers from the Keck School of Medicine of USC have published the first detailed description of the interplay between two cell types that allow lizards to regenerate their tails. This research, funded by the National Institutes of Health and published on August 10 in Nature Communications, focused on lizards’ unusual ability to rebuild cartilage, which replaces bone as the main structural tissue in regenerated tails after tail loss.  The discovery could provide insight for researchers studying how to rebuild cartilage damaged by osteoarthritis in humans, a degenerative and debilitating disease that affects about 32.5 million adults ...

Space weather and satellite security: Graz University of Technology and University of Graz supply new forecasting service for the ESA's Space Safety Programme

Space weather and satellite security: Graz University of Technology and University of Graz supply new forecasting service for the ESAs Space Safety Programme
2023-08-10
After a successful test phase, the Satellite Orbit DecAy (SODA) service, which was jointly developed by TU Graz and the University of Graz, officially became part of the ESA’s Space Safety Programme in mid-July. SODA provides accurate forecasts of the effects of solar storms on low Earth orbiting satellites. This makes TU Graz only the third Austrian institution contributing to this ESA programme. Seibersdorf Laboratories, and the University of Graz, through the Kanzelhöhe Observatory and the Institute of Physics, ...

New high-tech microscope using AI successfully detects malaria in returning travelers

2023-08-10
Each year, more than 200 million people fall sick with malaria and more than half a million of these infections lead to death. The World Health Organization recommends parasite-based diagnosis before starting treatment for the disease caused by Plasmodium parasites. There are various diagnostic methods, including conventional light microscopy, rapid diagnostic tests and PCR. The standard for malaria diagnosis, however, remains manual light microscopy, during which a specialist examines blood films with a microscope to confirm the presence of malaria parasites. ...

HKUST researchers pioneers technique to self-assemble high-performance biomolecular films

HKUST researchers pioneers technique to self-assemble high-performance biomolecular films
2023-08-10
A research team led by The Hong Kong University of Science and Technology (HKUST) has developed a novel technique to self-assemble a thin layer of amino acids with ordered orientation over a large area that demonstrates high piezoelectric strength, making the manufacturing of biocompatible and biodegradable medical microdevices, such as pacemaker and implantable biosensor, in the near future possible. The generation of bioelectricity from the piezoelectric effect – reversible conversion between mechanical and electrical energies – has physiological significance in living systems. ...

A platform for integrated spectrometers based on solution-processable semiconductors

A platform for integrated spectrometers based on solution-processable semiconductors
2023-08-10
Acquiring real-time spectral information in point-of-care diagnosis, internet-of-thing, and other lab-on-chip applications require spectrometers with hetero-integration capability and miniaturized feature. Compared to conventional semiconductors integrated by heteroepitaxy, solution-processable semiconductors provide a much-flexible integration platform due to their solution-processability, and, therefore, more suitable for the multi-material integrated system. However, solution-processable semiconductors are usually incompatible with the micro-fabrication processes, making them far from practical use in various lab-on-chip applications. In a new paper published ...

Researchers develop novel technology to quantify protein critical to blood clot formation through breath gas analysis

2023-08-10
Immunothrombosis, or the formation of microscopic blood clots during inflammation, is a major cause of morbidity among patients with sepsis or severe COVID-19. A key enzyme in this process is thrombin. To date, no method exists for early detection of immunothrombosis in a living organism.  A team of investigators led by Ali Hafezi-Moghadam, MD, PhD, director of the Molecular Biomarkers Nano-Imaging Laboratory (MBNI) at Brigham and Women’s Hospital, a founding member of Mass General Brigham healthcare system, and an associate professor of Radiology at Harvard Medical School, developed a novel technology to diagnose immunothrombosis by measuring ...

C-Path welcomes Sanofi to its Type 1 Diabetes Consortium to help advance drug development

2023-08-10
TUCSON, Ariz., August 9, 2023 — Critical Path Institute (C-Path) announced today that Sanofi, a global leader in immunology and diabetes care, has joined its Type 1 Diabetes Consortium (T1DC). Sanofi joins T1DC as part of its commitment to push the boundaries of innovation to improve the lives of those with diabetes. T1DC was established in 2017 with the goal to significantly advance the drug development landscape for T1D prevention and treatment. The consortium achieves this by fostering ...

How sure is sure? Incorporating human error into machine learning

2023-08-10
Researchers are developing a way to incorporate one of the most human of characteristics – uncertainty – into machine learning systems. Human error and uncertainty are concepts that many artificial intelligence systems fail to grasp, particularly in systems where a human provides feedback to a machine learning model. Many of these systems are programmed to assume that humans are always certain and correct, but real-world decision-making includes occasional mistakes and uncertainty. Researchers from the University of Cambridge, along with The Alan Turing Institute, Princeton, and Google DeepMind, have been attempting ...

Large study suggests people with low levels of vitamin K have less healthy lungs

Large study suggests people with low levels of vitamin K have less healthy lungs
2023-08-10
People with low levels of vitamin K in their blood are more likely to have poor lung function and to say they suffer with asthma, chronic obstructive pulmonary disease (COPD) and wheezing, according to a study published today (Thursday) in ERJ Open Research [1].   Vitamin K is found in leafy green vegetables, vegetable oils and cereal grains. It plays a role in blood clotting, and so helps the body to heal wounds, but researchers know very little about its role in lung health.   Researchers say their new findings do not alter the current advice on vitamin K intake, but they do support further research to ...

Sanford Burnham Prebys Cancer Center earns merit extension from NCI

Sanford Burnham Prebys Cancer Center earns merit extension from NCI
2023-08-10
Sanford Burnham Prebys’ Cancer Center has received a rare and prestigious Merit Extension Award from the National Cancer Institute (NCI), recognizing and rewarding its earlier accomplishments as well as current research plans. The award extends the center’s current 5-year Cancer Center Support Grant (CCSG) for an additional two years. There are only seven Basic Laboratory Cancer Centers in the NCI’s national network. These centers focus primarily on laboratory research: developing, conducting, translating and advancing fundamental discoveries to clinical testing and, ultimately, ...

Stem cell therapy rescues symptoms of Alzheimer’s disease

Stem cell therapy rescues symptoms of Alzheimer’s disease
2023-08-09
In the ongoing search for a cure for Alzheimer’s disease, a burgeoning branch of medicine is bringing new hope. Stem cell therapies are already being used to treat various cancers and disorders of the blood and immune system. In a new proof-of-concept study, scientists at University of California San Diego show stem cell transplants may also be a promising therapeutic against Alzheimer’s.  In the study, publishing this month in Cell Reports, the researchers demonstrate that transplanting hematopoietic ...

Penn Medicine neuroscientists identify brain mechanism that drives focus despite distractions

2023-08-09
PHILADELPHIA—Trying to finish your homework while the big game is on TV? “Visual-movement” neurons in the front of your brain can help you stay focused, according to a new study from neuroscientists in the Perelman School of Medicine at the University of Pennsylvania. In the study, published recently in Neuron, the scientists sought to illuminate the neural mechanism that helps the brain decide whether to focus visual attention on a rewarding task or an alluring distraction. By analyzing neuron activity in animal models as they faced this kind of attentional ...

Novel machine-learning method produces detailed population trend maps for 550 bird species

Novel machine-learning method produces detailed population trend maps for 550 bird species
2023-08-09
Scientists at the Cornell Lab of Ornithology have developed a novel way to model whether the populations of more than 500 bird species are increasing or decreasing. The method solves a nagging statistical problem by accounting for year-to-year changes in the behavior of people collecting the data. The result is detailed trend maps for each species down to an eight-mile radius--a major boost for local conservation efforts. Scientists used an approach called Double Machine Learning. Details are published in the journal Methods in Ecology and Evolution. “Changing human behavior presents a problem for statistical analysis ...

CDK9 Inhibitors: A promising combination partner in treating hematological malignancies

CDK9 Inhibitors: A promising combination partner in treating hematological malignancies
2023-08-09
“[...] CDK9 inhibitors could play a role in future treatments of hematological diseases and could be a great ally when combined with other therapeutic approaches.”  BUFFALO, NY- August 9, 2023 – A new research perspective was published in Oncotarget's Volume 14 on August 7, 2023, entitled, “CDK9 INHIBITORS: a promising combination partner in the treatment of hematological malignancies.” In their new perspective, researchers Daniel Morillo, Gala Vega and Victor Moreno from Hospital Fundación Jiménez Díaz discuss Cyclin-dependent ...

A novel theory of aging — independent of damage accumulation

A novel theory of aging — independent of damage accumulation
2023-08-09
“We argue that in multicellular organisms, neighbouring cells are in constant competition.” BUFFALO, NY- August 9, 2023 – A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, “A novel theory of ageing independent of damage accumulation.” The underlying cause or causes of aging are an enduring mystery, but in 1977 Kirkwood postulated that organisms might gain a fitness advantage by reducing investment in somatic maintenance if this allowed them to invest more resources in more crucial ...

Long-term use of certain acid reflux drugs linked to higher risk of dementia

2023-08-09
MINNEAPOLIS – People who take acid reflux medications called proton pump inhibitors for four-and-a-half years or more may have a higher risk of dementia compared to people who do not take these medications, according to new research published in the August 9, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. This study does not prove that acid reflux drugs cause dementia; it only shows an association. Acid reflux is when stomach acid flows into the esophagus, usually after a meal or when lying down. People with acid reflux may experience heartburn and ulcers. People ...

Research sheds new light on gene therapy for blood disorders

2023-08-09
Research from experts at Michigan Medicine, the Children’s Hospital of Philadelphia and Penn Medicine is breaking ground on new ways of treating blood disorders, such as sickle cell anemia, through gene therapy.  To cure blood disorders, patients must undergo high dose chemotherapy and bone marrow transplantation. This requires a match between the recipient and donor immune system, but ~30% of patients do not have a match. Even when they do the donor immune system can attack the patient, graft versus host disease. Gene therapy corrects the mutation in a patient’s own cells ...

Few in US recognize inequities of climate change

2023-08-09
ITHACA, N.Y. – Despite broad scientific consensus that climate change has more serious consequences for some groups – particularly those already socially or economically disadvantaged – a large swath of people in the U.S. doesn’t see it that way. A new national survey study found that just over one-third of U.S. adults believe climate change is impacting some groups more than others. Nearly half feel that climate change impacts all groups about equally. And when the question referenced race in climate impacts, even fewer people believed some groups are more adversely affected than others. “Our earlier research showed that ...

New research points to possible seasonal climate patterns on early Mars

New research points to possible seasonal climate patterns on early Mars
2023-08-09
New observations of mud cracks made by the Curiosity Rover show that high-frequency, wet-dry cycling occurred in early Martian surface environments, indicating that the red planet may have once seen seasonal weather patterns or even flash floods. The research was published today in Nature. “These exciting observations of mature mud cracks are allowing us to fill in some of the missing history of water on Mars. How did Mars go from a warm, wet planet to the cold, dry place we know today? These mud cracks show us that transitional time, when liquid water was less abundant but still active on the ...

US municipal bond market pricing may be biased by race, unphased by climate risk

US municipal bond market pricing may be biased by race, unphased by climate risk
2023-08-09
New research suggests that the US municipal bond market systemically misprices risk, as the pricing of municipal debt does not account for local physical climate risk, but does demand larger credit spreads from communities with a larger proportion of Black residents. Erika Smull of Duke University, US, and colleagues present these findings in the open-access journal PLOS ONE on August 9. Across the US, local governments issue municipal bonds to help fund various expenses, such as schools and sewer systems. ...

Two-thirds of turtle injuries and strandings recorded in the Maldives across 12 years arose from entanglement with lost and discarded fishing gear

Two-thirds of turtle injuries and strandings recorded in the Maldives across 12 years arose from entanglement with lost and discarded fishing gear
2023-08-09
Two-thirds of turtle injuries and strandings recorded in the Maldives across 12 years arose from entanglement with lost and discarded fishing gear ### Article URL:  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0289167 Article Title: Evaluation of sea turtle morbidity and mortality within the Indian Ocean from 12 years of data shows high prevalence of ghost net entanglement Author Countries: Republic of the Maldives Funding: The authors received no specific funding for this work. END ...

At one Antarctic research station, contaminant levels exceeding international guidelines across 18 years have resulted from historic practices that have polluted the local ecosystem

At one Antarctic research station, contaminant levels exceeding international guidelines across 18 years have resulted from historic practices that have polluted the local ecosystem
2023-08-09
At one Antarctic research station, contaminant levels exceeding international guidelines across 18 years have resulted from historic practices that have polluted the local ecosystem ### Article URL:  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0288485 Article Title: Contamination of the marine environment by Antarctic research stations: Monitoring marine pollution at Casey station from 1997 to 2015 Author Countries: Australia, Canada Funding: This research was funded by a Australian Antarctic Science research grants to JSS (AAS 2201, 2948, 4127, 4180, 4633) by the Australian Antarctic Division ...

ChatGPT-authored Japanese writing can be stylistically distinguished with up to 100% accuracy from human-authored text by machine learning algorithms

ChatGPT-authored Japanese writing can be stylistically distinguished with up to 100% accuracy from human-authored text by machine learning algorithms
2023-08-09
ChatGPT-authored Japanese writing can be stylistically distinguished with up to 100% accuracy from human-authored text by machine learning algorithms ### Article URL:  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0288453 Article Title: Distinguishing ChatGPT(-3.5, -4)-generated and human-written papers through Japanese stylometric analysis Author Countries: Japan Funding: This work was partly supported by JSPS KAKENHI Grant Number JP22K12726. The funders did not participate in this study design, data collection, analysis, or decision to publish, except their role in paying the English proofreading and Publication Fee. ...
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