Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer. As researchers have learned more and more about the cancer-immune system interplay, several antitumor immunotherapies have become FDA-approved and are now regularly used to treat multiple cancer types. Yet despite these advances, much remains unknown about how the immune system fights cancer — and about immunity in general, said Martin LaFleur, a postdoctoral fellow in the laboratory of Arlene ...

In a first-of-its-kind development, UBC Okanagan researchers, in collaboration with Drexel University, have created a new compound that can be used to 3D print telecommunication antennas and other connectivity devices. These 3D printed products, created by combining a two-dimensional compound called MXenes with a polymer, can be used as an alternative for metallic counterparts and can make a vast improvement in communication technology including elements such as antennas, waveguides and filters. Waveguides are everywhere, yet most people don’t know what they are, says Dr. Mohammad Zarifi, a researcher in UBC Okanagan’s Microelectronics and Gigahertz ...

An estimated 4 to 8 million older adults with mild cognitive impairment are currently driving in the United States, and one-third of them will develop dementia within five years. Individuals with progressive dementias are eventually unable to drive safely, yet many remain unaware of their cognitive decline. Currently, screening and evaluation services for driving can only test a small number of individuals with cognitive concerns, missing many who need to know if they require treatment. Nursing, engineering and neuropsychology researchers at Florida Atlantic University are testing and evaluating a readily and rapidly available, unobtrusive in-vehicle sensing ...

(LOS ANGELES) – February 29, 2024 - The Terasaki Institute for Biomedical Innovation (TIBI) is pleased to announce their selection of Professor Nicholas A. Peppas of The University of Texas at Austin as the recipient of the 2024 Paul Terasaki Distinguished Scientist Innovation Award. The award will be presented at TIBI’s 2nd annual Terasaki Innovation Summit, to be held March 27-29, 2024, at the UCLA Meyer & Renee Luskin Conference Center. The award was created in memory of Dr. Paul I. Terasaki, a pioneer in organ transplant research and innovation. It recognizes outstanding achievement in the field of biomedical ...

(LOS ANGELES) – February 29, 2024 - The Terasaki Institute for Biomedical Innovation (TIBI) is pleased to announce their selections of Assistant Professors Amir Manbachi of Johns Hopkins University and Ritu Raman of the Massachusetts Institute of Technology (MIT) as the recipients of the 2024 Hisako Terasaki Young Innovator Awards. The awards will be presented at TIBI’s 2nd annual Terasaki Innovation Summit, to be held March 27-29, 2024, at the UCLA Meyer & Renee Luskin Conference Center. The award was created in memory of Hisako Terasaki, philanthropist, accomplished artist, and wife ...

The latest Canada’s Food Guide presents a paradigm shift in nutrition advice, nixing traditional food groups, including meat and dairy, and stressing the importance of plant-based proteins. Yet, the full implications of replacing animal with plant protein foods in Canadians’ diets are unknown. New research at McGill University in collaboration with the London School of Hygiene & Tropical Medicine provides compelling evidence that partially substituting animal with plant protein foods can increase life expectancy and decrease greenhouse gas emissions. Importantly, ...

More than ever before, there is a growing interest in dedicating resources to stop the loss of biodiversity, as recently exemplified by the Kunming-Montreal Global Biodiversity Framework (GBF) decided at COP15 in December 2022. The GBF focuses on understanding why biodiversity is declining and what actions are needed to reverse this trend. However, according to researchers at McGill University, implementing the plan is challenging because information about biodiversity changes is not evenly available everywhere, and is uncertain in many places. With the available data, can the ...

Dr. Jung Unho's research team at the Hydrogen Research Department of the Korea Institute of Energy Research (KIER) has developed Korea's first clean hydrogen production technology. This technology is based on ammonia decomposition and does not use fossil fuels. The team's breakthrough could pave the way for a more sustainable and eco-friendly energy source. This allows for the production of high-purity hydrogen that meets international standards for hydrogen-powered vehicles, without the carbon dioxide emissions produced by using fossil fuels. Ammonia, a compound of hydrogen and nitrogen, has a hydrogen storage density 1.7 times ...

Today’s commercial solar panels can convert about 15% to 20% of the sunlight they absorb into electrical energy — but they could be much more efficient, according to researchers at Soochow University. The next generation of solar cells has already demonstrated 26.1% efficiency, they said, but more specific research directions are needed to make such efficiency the standard and expand beyond it.   They published their review of the current state of research on high-efficiency perovskite solar cells and their recommendations for future work in Energy Materials and Devices on February 4.   “Metal halide perovskite ...

Only half of 34 surveyed European countries have national guidelines on how to provide clinical care and treatment to children who have experienced sexual abuse. This finding was revealed in a study led by researchers at Barnafrid, a national knowledge centre in the field of violence and other abuse against children, at Linköping University in Sweden. The consequences for the affected children can be severe, according to the researchers. “Our findings suggest that children in Europe may not receive equal care. From a child rights perspective, this is unacceptable. ...

Using a novel methodology, researchers at The Hospital for Sick Children (SickKids) are the first in paediatric research to use data from an international real-world cohort to overcome the barriers associated with conducting randomized clinical trials in children with rare diseases.  The gold standard for evaluating new therapeutics is through randomized clinical trials, where one group of individuals receives treatment while another does not. Unfortunately, conducting this type of clinical trial proves challenging for many rare conditions due to the limited number of individuals with the condition, making meaningful comparisons difficult. Additionally, ...

Rice University researchers have developed a rapid, accurate test for diagnosing malaria that is significantly faster and easier to use than traditional tests. The advancement has the potential to improve patient outcomes, especially in rural regions with limited health care resources. Malaria remains a significant global health challenge with an estimated 247 million cases and more than 600,000 deaths annually, the majority of which occur in sub-Saharan Africa. The most severe form, cerebral malaria, has a high mortality ...

Metal nanomaterials have become an indispensable part of industrial and medical fields due to their unique and versatile properties. Their size, which imparts them with the desired physiochemical properties, is also the reason for environmental and health concerns. The nano-sized particles in nanomaterials have shown high reactivity towards biomolecules and often even toxicity towards biological cells.   Scientists have attributed this behavior of metal nanoparticles in interaction with biomolecules to phenomena like inflammation or oxidative stress. However, to ensure the safe usage of metal nanoparticles, ...

People at risk of Alzheimer’s disease have impaired spatial navigation prior to problems with other cognitive functions, including memory, finds a new study led by UCL researchers.  The research, published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, used virtual reality to test the spatial navigation of 100 asymptomatic midlife adults, aged 43-66, from the PREVENT-Dementia prospective cohort study. Participants had a hereditary or physiological risk of Alzheimer’s disease, due to either a gene (the APOE-ε4 allele) that puts them at risk of the condition, a family history of Alzheimer’s disease, ...

A team of researchers led by Alexander Pohle has unveiled a treasure trove of ancient fossils from Queensland's Black Mountain. The findings, published in PeerJ Life & Environment, shed new light on the complex three-dimensional siphuncle morphology of Plectronoceratids, a pivotal group of molluscs from the latest Cambrian period. The study surpasses the entirety of previously documented Plectronoceratid fossils, presenting over 200 well-preserved specimens. These fossils, meticulously collected by the late Mary Wade and her team during the 1970s and 1980s, offer unprecedented insights into the intricate structures of these ancient creatures. Pohle's team focused on specimens ...

A 30 million year-old fossil whale may not be the heaviest animal of all time after all, according to a new analysis by paleontologists at UC Davis and the Smithsonian Institution. The new analysis puts Perucetus colossus back in the same weight range as modern whales and smaller than the largest blue whales ever recorded. The work is published Feb. 29 in PeerJ. A fossil skeleton of Perucetus was discovered in Peru and described in a paper in Nature last year. The animal lived about 39 million years ago and belonged to an extinct group of early whales called ...

Improved neutron mirrors can increase the efficiency of material analysis in neutron sources such as the ESS, which is being built outside Lund, Sweden. The improved mirror has been developed by researchers at Linköping University by coating a silicon plate with extremely thin layers of iron and silicon mixed with boron carbide. Their study has been published in the journal Science Advances. “Instead of increasing the power on the neutron source, which is extremely expensive, it’s better to focus on improving optics,” says Fredrik Eriksson, researcher at the Thin Film Physics Division at Linköping University. Together with protons, neutrons ...

Researchers have found water vapour in the disc around a young star exactly where planets may be forming. Water is a key ingredient for life on Earth and is also thought to play a significant role in planet formation, yet, until now, astronomers have never been able to map how water is distributed in a stable, cool disc — the type of disc that offers the most favourable conditions for planets to form around stars. For the first time, astronomers have weighed the amount of water vapour around a typical planet-forming star.     The new findings were made possible thanks to the Atacama Large Millimeter/submillimeter Array (ALMA) - a collection of telescopes ...

A promising new fungicide to fight devastating crop diseases has been identified by researchers at the University of California, Davis. The chemical, ebselen, prevented fungal infections in apples, grapes, strawberries, tomatoes and roses and improved symptoms of pre-existing fungal infection in rice. Fungal pathogens account for almost a quarter of global crop losses. In the United States, these losses amount to around $150 billion per year. However, fungicide development has been slow for the past 50 years, largely because researchers have had difficulty identifying molecular pathways to target. In a new study published Feb. 29 in ...

FINDINGS Researchers from the UCLA Health Jonsson Comprehensive Cancer Center show for the first time that a gene usually linked to giant axonal neuropathy, a rare and severe neurological condition, also plays a role in inhibiting aggressive tumor cell growth in head and neck cancers. The team found when the specific genetic variant (GAN gene exon 8 SNP T allele) of the GAN gene isn't present, it leads to the production of certain proteins that make cancer cells more likely to spread and become resistant to treatment. These findings suggest that the presence of the genetic variant and higher expression of the GAN gene product gigaxonin may contribute ...

Thirteen exceptional endocrine researchers from across Europe and the US have been selected as the 2024-26 cohort of the EJE Rising Star Editorial Board by the European Journal of Endocrinology (EJE), a journal published by the European Society of Endocrinology (ESE). This prestigious opportunity is given to individuals selected by EJE Editors who show promise, achievement and trajectory as leading clinical and translational researchers in endocrinology, with high potential to serve as future editors of EJE. Through the Rising Stars Programme, awardees are granted the following: membership ...

As an important reproductive organ of angiosperms, flowers have clear purposefulness and adaptive significance in their various characteristics. As a typical floral evolutionary feature, the floral spur is a tubular structure extending from the petal, which has undergone several independent evolutions in angiosperms (e.g., Impatiens, Aquilegia, Linaria, etc.). Meanwhile, it plays a vital role in the pollination process because of its properties of secreting and storing nectar. In addition, the morphology (length, diameter, degree of distortion), ...

29 February 2024: Lockdowns imposed during the COVID-19 pandemic had an impact on the gut microbiome development of babies born during these periods according to new research from RCSI University of Medicine and Health Sciences, Children’s Health Ireland and APC Microbiome Ireland (APC), a world leading SFI Research Centre, based in University College Cork.  Our gut microbiome, an ecosystem of microbes that live in our digestive tract, plays an essential role in human health. The study published in Allergy is the first to specifically explore the gut health of newborns in the pandemic. ...

If we could stand in a landscape that our Mesolithic ancestors called home, what would we see around us? Scientists have devised a method of analyzing preserved hazelnut shells to tell us whether the microhabitats around archaeological sites were heavily forested or open and pasture-like. This could help us understand not only what a local environment looked like thousands of years ago, but how humans have impacted their habitats over time.   “By analyzing the carbon in hazelnuts recovered from archaeological sites in southern Sweden, from Mesolithic hunter-gatherer ...

The city of Cambridge and the Wellcome Campus hosted the Final General Assembly of the EU-funded project BiCIKL (acronym for Biodiversity Community Integrated Knowledge Library): a 36-month endeavour that saw 14 member institutions and 15 research infrastructures representing diverse actors from the biodiversity data realm come together to improve bi-directional links between different platforms, standards, formats and scientific fields. Consortium members who could not attend the meeting in Cambridge joined the meeting remotely. The ...