PHILADELPHIA--Antibodies aren't the only immune cells needed to fight off COVID-19 -- T cells are equally important and can step up to do the job when antibodies are depleted, suggests a new Penn Medicine study of blood cancer patients with COVID-19 published in Nature Medicine. The researchers found that blood cancer patients with COVID-19 who had higher CD8 T cells, many of whom had depleted antibodies from cancer treatments, were more than three times likelier to survive than patients with lower levels of CD8 T cells. "It's clear T cells are critical in terms of the early infection and to help control the virus, but we also showed that they can compensate for B cell and antibody responses, which blood cancer patients are likely missing because of the drugs," said co-senior author Alexander ...

PULLMAN, Wash. -- A new fungus strain could provide a chemical-free method for eradicating mites that kill honey bees, according to a study published this month in Scientific Reports. A team led by Washington State University entomologists bred a strain of Metarhizium, a common fungus found in soils around the world, to work as a control agent against varroa mites. Unlike other strains of Metarhizium, the one created by the WSU research team can survive in the warm environments common in honey bee hives, which typically have a temperature of around 35 Celsius (or 95 F). "We've known that metarhizium could kill mites, but it was expensive and didn't last long because the fungi died in the hive heat," said Steve Sheppard, professor in WSU's Department of Entomology and corresponding ...

A research group at the University of Córdoba evaluated the commercial mixture formulated in a laboratory and the tank-based mixture of two herbicides to determine which method is more effective in terms of weed control and environmental impact. In 2017 the company Nufarm Europe proposed to the Higher Technical School of Agricultural and Forestry Engineering (ETSIAM) at the UCO a study of the results of two products having a significant agronomic impact: the herbicides glyphosate and 2,4-D (synthetic auxin). After three years of research, they concluded that the commercial mix produced in the company's laboratories is more effective than manual mixes produced in tanks. To do this, they used in vivo techniques (tests with greenhouse ...

MAY 26, 2021 -- Researchers from UTSA, the University of Central Florida (UCF), the Air Force Research Laboratory (AFRL) and SRI International have developed a new method that improves how artificial intelligence learns to see. Led by Sumit Jha, professor in the Department of Computer Science at UTSA, the team has changed the conventional approach employed in explaining machine learning decisions that relies on a single injection of noise into the input layer of a neural network. The team shows that adding noise--also known as pixilation--along multiple layers of a network provides a more robust representation of an image that's recognized by the AI ...

The Menetries' tiger moth (Arctia menetriesii) is one of the rarest and most poorly studied Palaearctic moth species. Even though its adult individuals are large and brightly coloured, they are difficult to spot, because they aren't attracted to light, they're not active at night, and they fly reluctantly. Currently, the species only inhabits two countries - Finland and the Russian Federation, and is included in the Red Lists of both, as Data Deficient in the former and Vulnerable in the latter. For 13 years, researcher Evgeny Koshkin of the Institute of Water and Ecology Problems of the Far ...

Men aged 65 and over should monitor their sleep patterns and seek medical advice after a warning from Flinders University experts that disrupted slumber can be linked to cognitive dysfunction. In a new article published in the Journal of Sleep Research, the Adelaide Institute for Sleep Health research group studied a group of 477 middle-aged and older men's attention and processing speed in relation to their sleep. The participants from the Florey Adelaide Male Ageing Study undertook cognitive testing and a successful sleep study. "Less deep sleep and more light sleep is related to slower responses on cognitive function tests," says lead author Jesse Parker. ...

To really appreciate what a team of researchers led by Maksym Kovalenko and Maryna Bodnarchuk has achieved, it is best to start with something mundane: Crystals of table salt (also known as rock salt) are familiar to anyone who has ever had to spice up an overtly bland lunch. Sodium chloride - NaCl in chemical terms - is the name of the helpful chemical; it consists of positively charged sodium ions (Na+) and negatively charged chloride ions (Cl-). You can imagine the ions as beads that strongly attract each other forming densely packed and rigid crystals like the ...

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new biomaterial made entirely from discarded bullfrog skin and fish scales that could help in bone repair. The porous biomaterial, which contains the same compounds that are predominant in bones, acts as a scaffold for bone-forming cells to adhere to and multiply, leading to the formation of new bone. Through laboratory experiments, the NTU Singapore team found that human bone-forming cells seeded onto the biomaterial scaffold successfully attached themselves and started multiplying - a sign of growth. They also found that the risk of the biomaterial triggering an inflammatory response is low. Such a scaffold could be used to help with the regeneration of ...

The parents of children with rare diseases face exceptional circumstances which influence their role as parents. Sometimes, the role of caregivers is added to that of parents. On other occasions, especially with the most serious cases, the former becomes more prominent than the latter. There are also cases in which both roles coexist separately, allowing them to be parents and caregivers in equal measure. However, whichever group they belong to, they need trust and to overcome fear in order to live their experience without overwhelming anxiety. This is one of the findings of an open-access study published in the International Journal of Environmental ...

NUI Galway study confirms that the Noble False Widow spider does have public health implications Research team have established a DNA database to allow clinicians dealing with cases to confirm the species identity using genetic analysis Epidemiology of bites reveals that almost all bites occurred in and around the home, and 88% of bites occurred when the victim was either asleep in bed or when the spider was trapped in clothing In parts of Ireland and Britain, the False Widow spider has become one of the most common species of spiders found in and around urban habitats A team of scientists from NUI Galway have published a new study showing that Noble False Widow spiders ...

Eating habits amongst the young changed during the lockdown imposed due to COVID-19 and worsened in the case of those belonging to socioeconomically disadvantaged groups. These are the chief findings of an open access study published in specialist journal Nutrients, headed by researchers Alícia Aguilar Martínez, of the Universitat Oberta de Catalunya, and Marina Bosque Prous, of the UOC and UManresa, as part of the DESKcohort project of the interuniversity Epidemiology and Public Health research group GRESP. The study, of 303 Catalan young people aged between 12 and 18, sought to establish how this age group's diet had changed from March to May 2020, in terms of both eating behaviours and the products consumed. The goal was to collect data to ascertain ...

For years, food producers who make lightly preserved, ready-to-eat food have had to follow a set of guidelines to stop growth of Clostridium botulinum bacteria and production of a strong neurotoxin. The toxin can cause a serious illness called botulism. For refrigerated products, the guidelines for controlling Clostridium botulinum indicate that the water contained in the products should have a salt content of at least 3.5%. Unfortunately, this hampers efforts to develop salt-reduced products, even though such products would benefit public health, as most consumers eat more salt than recommended. If food producers want to launch products that contain e.g. less salt, they have had to conduct laboratory experiments to document ...

Current neural network algorithms produce impressive results that help solve an incredible number of problems. However, the electronic devices used to run these algorithms still require too much processing power. These artificial intelligence (AI) systems simply cannot compete with an actual brain when it comes to processing sensory information or interactions with the environment in real time. Neuromorphic chip detects high-frequency oscillations Neuromorphic engineering is a promising new approach that bridges the gap between artificial and natural intelligence. An interdisciplinary research team at the University of Zurich, the ETH Zurich, and the ...

What keeps consumers hooked on high sugar soft drink? Advertising, of course. But why are some consumers more adept at ignoring these cues than others? A new study from Flinders University, published in Appetite, found participants with an automatic bias towards soft drinks - or difficulty resisting sweet drinks compared to non-sweetened control beverages (e.g., water) - were more responsive to the ads than those without these tendencies. The Australian study compared the ability of 127 university-age students (18-25 year olds) to withstand or succumb to the urge to reach for a soft drink when viewing television advertisements. "Perhaps, then, we can start targeting people who show these ...

Analysis using a national medical database revealed that the cumulative incidence of autism spectrum disorders (ASD) in children born in 2009-2014 was 2.75% by the age of five. A research group led by Associate Professor Daimei Sasayama and Professor Hideo Honda of the Department of Child and Adolescent Development Psychiatry, Shinshu University School of Medicine, used a national medical database to analyze autism spectrum disorders in Japan. It was reported that the cumulative incidence showed an increasing trend for each year of birth, and that there were regional differences. This cumulative incidence of ASD is the highest in the world based on medical diagnosis, suggesting high diagnostic ...

Poor sleep impacts the risk of long-term cognitive decline in Hispanic/Latino middle aged and older adults differently than it does in non-Hispanic adults, according to research led by University of Miami Miller School of Medicine neurology faculty and the largest long-term study of U.S. Hispanic/Latinos to date. During seven years of follow-up, Hispanics/Latinos were more likely to develop cognitive declines in processing speed, mental flexibility, and verbal memory, if they had sleep disordered breathing, such as obstructive sleep apnea, and long sleep duration of nine or more hours. The risk was especially high in middle-aged adults without metabolic syndrome and women without obesity or metabolic syndrome ...

Oysters' exposure to plastics is concerning, particularly because these materials can accumulate and release metals which are then absorbed by the molluscs. According to a recent study published in the journal Chemosphere, the combined presence of nanoplastics and arsenic affects the biological functions of oysters. This study was conducted by the Institut national de la recherche scientifique (INRS) in Québec City and the French National Centre for Scientific Research (CNRS) at the University of Bordeaux in France. The international research team chose to study arsenic, since it is one of the most common metals absorbed ...

PULLMAN, Wash. - For decades, wealthy nations have transported plastic trash, and the environmental problems that go with it, to poorer countries, but researchers have found a potential bright side to this seemingly unequal trade: plastic waste may provide an economic boon for the lower-income countries. In a study published in the Journal of World Systems Research, Yikang Bai of Washington State University and Jennifer Givens of Utah State University analyzed 11 years of data on the global plastics trade against economic measures for 85 countries. They found that the import of plastic waste was associated with growth in gross domestic product per capita in the lower-income countries. "Our study offers a nuanced understanding of the global trade in plastic waste," said Bai, ...

DALLAS, May 27, 2021 -- Adults who have obsessive-compulsive disorder (OCD) were more than three times as likely to have an ischemic stroke later in life compared to adults who do not have OCD, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association. "The results of our study should encourage people with OCD to maintain a healthy lifestyle, such as quitting or not smoking, getting regular physical activity and managing a healthy weight to avoid stroke-related risk factors," said study senior author Ya-Mei Bai, M.D., Ph.D., a professor in the department of psychiatry at Taipei Veterans General Hospital ...

Researchers have mapped in fine detail the genetic changes malaria parasites go through as they prepare to infect people. The atlas maps the malaria parasite Plasmodium falciparum in unprecedented cellular detail as it develops inside a mosquito and prepares to infect humans through a bite. This detailed investigation could lead to new ways to block key stages in the parasite's development and prevent transmission through future drugs or vaccines. Mosquitoes are increasingly resistant to pesticides, and the parasite that causes malaria is also becoming increasingly ...

A cutting-edge digital tool that will make it cheaper, safer and faster for pharmaceutical companies to predict protein stability - a vital step in the development of new medicines - is being rolled out by scientists from the UK's University of Bath through their spin-out company, BLOC Labs. The tool, launched this week, will help researchers identify the most promising protein molecules for drug development. It has the potential to play an important role in the creation of monoclonal antibodies (mAbs). The market for these therapeutic antibodies is worth over £70 bn. Monoclonal antibodies are a type of protein derived from natural antibodies and then refined and mass produced in the lab. They are steadily transforming the way we treat and prevent diseases, from ...

Nearly three years after the Trump administration's "Zero Tolerance" policy went into effect, more than 445 children remain separated from their families, largely due to insufficient identifying paperwork and U.S. immigration officials' failures to plan, track and reunite separated families. In a Policy Forum, Elizabeth Barnert and colleagues - an interdisciplinary group of physicians, scientists and human rights advocates - argue that a well-defined, replicable, scalable, and sustainable framework to collect and manage sensitive DNA data is urgently needed in order to play a part in helping reunite separated migrant families safely and ethically. ...

Research across a wide range of languages shows that children's home literacy environment can often predict their language and literacy skills. However few studies, especially for English speaking children, examine how children's development affects what parents do and not just how parents affect their children's development. A new longitudinal study examined such bidirectional relationships between home literacy environment and children's progress in learning to read between grades 1 and 3. Results show that parents adjust their reading activities with their children over time, taking into account the level of difficulty the children are having in learning to ...

Research shows that poor sleep health may disproportionately affect children of color from families of low socioeconomic status and place them at risk for behavior problems and lower academic performance. However, few sleep studies utilize standard measures of both classroom behavior and academic achievement. A new longitudinal study examined the relation between sleep, classroom behavior, and academic achievement scores among primarily Black children growing up in historically disinvested neighborhoods. Disinvested refers to neighborhoods in which public and private funding, city services, or other necessary resources have been denied or withheld, and which are often segregated ...

INDIANAPOLIS -- A pilot project using an online survey to gather data on COVID-19 symptoms received more than 87,000 responses from around the world, providing important insight into the spread of disease. Project leaders from Regenstrief Institute, Indiana University and Microsoft believe these questionnaires could be a valuable tool for population health. The 7-question survey was launched in multiple languages during April 2020, as lockdowns were implemented to slow the spread of COVID-19. A link to the survey was placed in banner ads in Microsoft News articles. Respondents ...