Cell architecture: Finding common ground
2014-10-16
Stanford, CA—When it comes to cellular architecture, function follows form.
Plant cells contain a dynamic cytoskeleton which is responsible for directing cell growth, development, movement, and division. So over time, changes in the cytoskeleton form the shape and behavior of cells and, ultimately, the structure and function of the organism as a whole. New work led by Carnegie's David Ehrhardt hones in on how one particular organizational protein influences cytoskeletal and cellular structure in plants, findings that may also have implications for cytoskeletal ...
Misfolded proteins clump together in a surprising place
2014-10-16
KANSAS CITY, MO — Scientists at the Stowers Institute for Medical Research have made a surprising finding about the aggregates of misfolded cellular proteins that have been linked to aging-related disorders such as Parkinson's disease. The researchers report their results in the October 16, 2014 online issue of the journal Cell.
Using 3-D time-lapse movies to track the fate of misfolded proteins in yeast cells, the researchers determined that about 90 percent of aggregates form on the surface of the endoplasmic reticulum (ER), a location of protein synthesis in ...
That pregnant feeling makes a fly start nesting
2014-10-16
DURHAM, N.C. -- Across the animal kingdom, it's not uncommon for pregnancy to change an expectant mom's behavior. Even female flies have their own rudimentary way of "nesting," which appears to be brought on by the stretch of their egg-filled abdomens rather than the act of mating, according to a Duke study published online October 16 in Cell Reports.
After mating, the female fruit fly Drosophila melanogaster dramatically shifts priorities as she prepares to lay eggs.
"For example, the virgin flies are interested in sex. Once they're mated, it's very striking -- they ...
Study recommends ongoing assessment of impact of offshore wind farms on marine species
2014-10-16
SOLOMONS, MD (October 16, 2014)--Offshore wind power is a valuable source of renewable energy that can help reduce carbon emissions. Technological advances are allowing higher capacity turbines to be installed in deeper water, but there is still much unknown about the effects on the environment. In a recent paper, University of Maryland Center for Environmental Science researcher Helen Bailey and colleagues review the potential impacts of offshore wind developments on marine species and make recommendations for future monitoring and assessment as interest in offshore wind ...
MicroRNA molecules serve as on/off switches for inflammation
2014-10-16
(SALT LAKE CITY)—University of Utah scientists have identified two microRNA molecules that control chronic inflammation, a discovery that one day may help researchers prevent certain fatal or debilitating conditions before they start.
"We're living at a time where the aging population is growing," said Ryan O'Connell, D.Phil., assistant professor of pathology, whose lab made the discovery. "The question is: how can we predict and prevent the onset of disorders that emerge upon growing older?"
The research will be published this Thursday in Immunity, a top immunology ...
Scripps Research Institute scientists identify trigger for crucial immune system cell
2014-10-16
LA JOLLA, CA—October 16, 2014—Scientists at The Scripps Research Institute (TSRI) have identified the long-sought activating molecules for a rare but crucial subset of immune system cells that help rally other white blood cells to fight infection.
In the process, the team also uncovered a previously unsuspected link between the mammalian immune system and the communication systems of simpler organisms such as bacteria.
The findings, published online ahead of print on October 16 by the journal Immunity, could lead to novel therapeutic approaches for diseases ...
Pitt/McGowan Institute team discovers stem cells in the esophagus
2014-10-16
PITTSBURGH, Oct. 16, 2014 – Despite previous indications to the contrary, the esophagus does have its own pool of stem cells, said researchers from the University of Pittsburgh School of Medicine in an animal study published online today in Cell Reports. The findings could lead to new insights into the development and treatment of esophageal cancer and the precancerous condition known as Barrett's esophagus.
According to the American Cancer Society, more than 18,000 people will be diagnosed with esophageal cancer in the U.S. in 2014 and almost 15,500 people will ...
Mysterious Midcontinent Rift is a geological hybrid
2014-10-16
An international team of geologists has a new explanation for how the Midwest's biggest geological feature -- an ancient and giant 2,000-mile-long underground crack that starts in Lake Superior and runs south to Oklahoma and to Alabama -- evolved.
Scientists from Northwestern University, the University of Illinois at Chicago (UIC), the University of Gottingen in Germany and the University of Oklahoma report that the 1.1 billion-year-old Midcontinent Rift is a geological hybrid, having formed in three stages: it started as an enormous narrow crack in the Earth's crust; ...
Simple test may predict surgical wound healing complications
2014-10-16
MAYWOOD, Ill. (Oct. 16, 2014) -- As many as 35 percent of patients who undergo surgery to remove soft tissue sarcomas experience wound-healing complications, due to radiation they receive before surgery.
Now a study has suggested that a simple test called transcutaneous oximetry may be able to predict which of these patients are most likely to experience wound-healing complications, potentially enabling surgeons to take extra precautions.
Lukas Nystrom, MD, of Loyola University Medical Center presented his findings during the 2014 annual meeting of the Musculoskeletal ...
Should first responders use acupuncture & integrative medicine in natural disasters & battle zones?
2014-10-16
New Rochelle, NY, October 16, 2014—Delivering traditional emergency medical care at ground zero of natural disasters and military conflicts is challenging. First responders trained in simple integrative medicine approaches such as acupuncture, hypnosis, or biofeedback can provide adjunctive treatment to help relieve patients' pain and stress. How to teach and utilize modified techniques and their potential benefit are described in a Review article in Medical Acupuncture, a peer-reviewed journal from by Mary Ann Liebert, Inc., publishers. The article is available free ...
New study finds that the probability of unprotected intercourse in hookups doubles between freshman
2014-10-16
An article released by Social Forces titled, "Casual Contraception in Casual Sex: Life-Cycle Change in Undergraduates' Sexual Behavior in Hookups" by Jonathan Marc Bearak (New York University) explores the changes in undergraduate uncommitted sexual behavior during years 1–4 of college. The article provides reasoning for the decline in the use of condoms, and explains how changes in the odds of coitus and condom use depend on fam¬ily background, school gender imbalance, and whether the partners attend the same college.
The results show that the odds of unprotected ...
Dispelling a misconception about Mg-ion batteries
2014-10-16
Lithium (Li)-ion batteries serve us well, powering our laptops, tablets, cell phones and a host of other gadgets and devices. However, for future automotive applications, we will need rechargeable batteries with significant increases in energy density, reductions in cost and improvements in safety. Hence the big push in the battery industry to develop an alternative to the Li-ion technology.
One promising alternative would be a battery based on a multivalent ion, such as magnesium (Mg). Whereas a Li-ion with a charge of +1 provides only a single electron for an electrical ...
Myth-conceptions: How myths about the brain are hampering teaching
2014-10-16
Myths about the brain are common among teachers worldwide and are hampering teaching, according to new research.
Teachers in the UK, Holland, Turkey, Greece and China were presented with seven so-called 'neuromyths' and asked whether they believe them to be true.
A quarter or more of teachers in the UK and Turkey believe a student's brain would shrink if they drank less than six to eight glasses of water a day, while around half or more of those surveyed believe a student's brain is only 10 per cent active and that children are less attentive after sugary drinks and ...
First-ever patient care guidelines in prevention of acute exacerbations of COPD
2014-10-16
October 16, 2014, Glenview, Illinois—The American College of Chest Physicians (CHEST) and the Canadian Thoracic Society (CTS) announced today the release of Prevention of Acute Exacerbation of Chronic Obstructive Pulmonary Disease: American College of Chest Physicians and Canadian Thoracic Society Guideline in the journal CHEST. The guideline, a first of its kind, provides evidence-based recommendations aimed at prevention of COPD exacerbations, which can cause frequent hospital readmissions, death during or after a hospital stay, and can potentially greatly reduce ...
Survey: Texans share lessons learned as second enrollment period of ACA health insurance nears
2014-10-16
HOUSTON – (Oct. 16, 2014) – While most Texans used healthcare.gov earlier this year to get information or to enroll in a health insurance plan under the Affordable Care Act (ACA), larger percentages of Texans found talking to the call center or a navigator was the most helpful. Those are just some of the lessons learned in a report released today by the Episcopal Health Foundation and Rice University's Baker Institute for Public Policy.
The report found 62 percent of Texans used the healthcare.gov website to learn about ACA Marketplace health plans during ...
Light bending material facilitates the search for new particles
2014-10-16
Particle physicists have a hard time identifying all the elementary particles created in their particle accelerators. But now researchers at Chalmers University of Technology have designed a material that makes it much easier to distinguish the particles.
To investigate the matter's smallest constituents, physicists have particles colliding with each other at very high speeds, for example in the particle accelerator LHC at Cern. The collisions create bursts of common and rare particles, all invisible to the eye.
To identify them researchers need to detect the cone of ...
Cadavers beat computers for learning anatomy
2014-10-16
EAST LANSING, Mich. --- Despite the growing popularity of using computer simulation to help teach college anatomy, students learn much better through the traditional use of human cadavers, according to new research that has implications for health care.
Cary Roseth, associate professor of educational psychology at Michigan State University, said the study suggests cadaver-based instruction should continue in undergraduate human anatomy, a gateway course to medical school, nursing and other health and medical fields.
In the United States, most anatomy courses still emphasize ...
S-equol supplements associated with improved measures of reproductive health in postmenopausal women
2014-10-16
Northridge, Calif. (October 16, 2014) – Post-menopausal women experienced improvements in vaginal atrophy, with no significant effect on hormone levels or genital bleeding, after 12 weeks of daily 10 milligram (mg) doses of an investigational fermented soy germ-based nutritional supplement previously shown to help relieve certain menopause symptoms, according to a new peer-reviewed pilot study reported in a poster at the North American Menopause Society (NAMS) annual scientific meeting.
"These data documented improved vaginal epithelium, without significant abnormalities ...
Curious signal hints at dark matter
2014-10-16
Space scientists at the University of Leicester have detected a curious signal in the X-ray sky – one that provides a tantalising insight into the nature of mysterious Dark Matter.
The Leicester team has found what appears to be a signature of 'axions', predicted 'Dark Matter' particle candidates – something that has been a puzzle to science for years.
In a study being published on Monday 20 October in the Monthly Notices of the Royal Astronomical Society, the University of Leicester scientists describe their finding of a signal which has no conventional ...
Executive scandal hurts job prospects even for entry-level employees
2014-10-16
October 16, 2014 – There's more bad news for job seekers with a scandal-hit company like Lehman Brothers or Countrywide Mortgage on their résumés. As if it weren't already hard enough to get a new job in this market, people who worked for one of those companies have tarnished reputations to overcome: New research finds that moral suspicion from higher-ups' wrongdoing spills down to people lower in an organization, even if they did not work directly under the moral transgressor.
"We became interested in the plight of people whose career trajectories were ...
Brain's compass relies on geometric relationships, say Penn Researchers
2014-10-16
VIDEO:
The brain has a complex system for keeping track of which direction you are facing as you move about; remembering how to get from one place to another would otherwise...
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The brain has a complex system for keeping track of which direction you are facing as you move about; remembering how to get from one place to another would otherwise be impossible. Researchers from the University of Pennsylvania have now shown how the brain anchors this ...
How, when, and why industrial ecology is good for business
2014-10-16
Industrial ecology, a rapidly growing field focused on sustainable production and consumption, has contributed numerous important tools to modern environmental management — life cycle assessment; "industrial symbiosis," or the by-product exchange between neighboring facilities; "design for environment"; and the use of material flow analysis to track resource use in supply chains, companies, and economies.
A new special feature of Yale's Journal of Industrial Ecology, titled "Industrial Ecology as a Source of Competitive Advantage," presents new research on how, ...
Study shows inpatient palliative care reduces hospital costs and readmissions
2014-10-16
New Rochelle, NY, October 15, 2014—Palliative care provided in the hospital offers known clinical benefits, and a new study shows that inpatient palliative care can also significantly lower the cost of hospitalization and the rate of readmissions. Further, the study shows the hospital can get the expertise it needs through a collaborative relationship with a community hospice. The results of a comparative study are published in Journal of Palliative Medicine, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal ...
Novel RNAi-based therapy for anemia stimulates liver to produce EPO
2014-10-16
New Rochelle, NY, October 16, 2014—To treat the debilitating anemia associated with reduced erythropoietin (EPO) production by the kidneys in chronic renal disease, patients are often given recombinant human EPO to increase hemoglobin levels. But that treatment has risks. A new approach that uses a small interfering RNA (siRNA) drug to stimulate natural EPO production by the liver has shown promising results in nonhuman primates, as reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers. The article is available free ...
Public health in the 21st century
2014-10-16
Ann Arbor, MI, October 16, 2014 – Although disease outbreaks and epidemics drawing worldwide attention emphasize the importance and acute need for public health professionals, the world faces a longer-term challenge—a public health workforce that is truly effective in the 21st century. In a new supplement to the American Journal of Preventive Medicine, experts address critical challenges to public health, from workforce development, capacity building, partnership and collaborations, and changes and needs in workforce composition.
As the U.S. healthcare system ...
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