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Extreme weather in the Arctic problematic for people, wildlife

Extreme weather in the Arctic problematic for people, wildlife
2014-11-20
The residents of Longyearbyen, the largest town on the Norwegian arctic island archipelago of Svalbard, remember it as the week that the weather gods caused trouble. Temperatures were ridiculously warm - and reached a maximum of nearly +8 degrees C in one location at a time when mean temperatures are normally -15 degrees C. It rained in record amounts. Snow packs became so saturated that slushy snow avalanches from the mountains surrounding Longyearbyen covered roads and took out a major pedestrian bridge. Snowy streets and the tundra were transformed into icy, ...

New computer model predicts gut metabolites to better understand gastrointestinal disease

2014-11-20
MEDFORD/SOMERVILLE, Mass-- Tufts University School of Engineering researchers and collaborators from Texas A&M University have published the first research to use computational modeling to predict and identify the metabolic products of gastrointestinal (GI) tract microorganisms. Understanding these metabolic products, or metabolites, could influence how clinicians diagnose and treat GI diseases, as well as many other metabolic and neurological diseases increasingly associated with compromised GI function. The research appears in the November 20 edition of Nature Communications ...

A new tool for identifying onset of local influenza outbreaks

A new tool for identifying onset of local influenza outbreaks
2014-11-20
AMHERST, Mass. -- Predicting the beginning of influenza outbreaks is notoriously difficult, and can affect prevention and control efforts. Now, just in time for flu season, biostatistician Nicholas Reich of the University of Massachusetts Amherst and colleagues at Johns Hopkins have devised a simple yet accurate method for hospitals and public health departments to determine the onset of elevated influenza activity at the community level. Hospital epidemiologists and others responsible for public health decisions do not declare the start of flu season lightly, Reich ...

Unravelling the mystery of gamma-ray bursts

Unravelling the mystery of gamma-ray bursts
2014-11-20
A team of scientists hope to trace the origins of gamma-ray bursts with the aid of giant space 'microphones'. Researchers at Cardiff University are trying to work out the possible sounds scientists might expect to hear when the ultra-sensitive LIGO and Virgo detectors are switched on in 2015. It's hoped the kilometre-scale microphones will detect gravitational waves created by black holes, and shed light on the origins of the Universe. Researchers Dr Francesco Pannarale and Dr Frank Ohme, in Cardiff University's School of Physics and Astronomy, are exploring the potential ...

Fat a culprit in fibrotic lung damage

2014-11-20
(PHILADELPHIA) - Pulmonary fibrosis has no cure. It's caused by scarring that seems to feed on itself, with the tougher, less elastic tissue replacing the ever moving and stretching lung, making it increasingly difficult for patients to breathe. Researchers debate whether the lung tissue is directly damaged, or whether immune cells initiate the scarring process - an important distinction when trying to find new ways to battle the disease. Now research shows that both processes may be important, and suggest a new direction for developing novel therapies. The work will publish ...

Job authority increases depression symptoms in women, decreases them in men

2014-11-20
WASHINGTON, DC, November 17, 2014 -- A new study finds that having job authority increases symptoms of depression among women, but decreases them among men. "Women with job authority -- the ability to hire, fire, and influence pay -- have significantly more symptoms of depression than women without this power," said Tetyana Pudrovska, an assistant professor in the Department of Sociology at the University of Texas at Austin and the lead author of the study. "In contrast, men with job authority have fewer symptoms of depression than men without such power." Titled, ...

Heterosexuals have egalitarian views on legal benefits for same-sex couples, not on PDA

2014-11-20
WASHINGTON, DC, November 18, 2014 -- A new study indicates that heterosexuals have predominately egalitarian views on legal benefits for -- but not public displays of affection (PDA) by -- same-sex couples. "We found that, for the most part, heterosexuals are equally as supportive of legal benefits for same-sex couples as they are for heterosexual couples, but are much less supportive of public displays of affection for same-sex couples than they are for heterosexuals," said Long Doan, a PhD candidate in the Department of Sociology at Indiana University and the lead author ...

Only half of patients take their medications as prescribed

2014-11-20
The cost of patients not taking their medications as prescribed can be substantial in terms of their health. Although a large amount of research evidence has tried to address this problem, there are no well-established approaches to help them, according to a new systematic review published in the Cochrane Library. The authors of the review examined data from 182 trials testing different approaches to increasing medication adherence and patient health. Even though the review included a significant number of the best studies to date, in most cases, trials had important problems ...

For women, job authority adds to depression symptoms

2014-11-20
AUSTIN, Texas -- Job authority increases symptoms of depression among women, but decreases them among men, according to a new study from University of Texas at Austin sociologist Tetyana Pudrovska. "Women with job authority -- the ability to hire, fire, and influence pay -- have significantly more symptoms of depression than women without this power," said Pudrovska, the lead author of the study. "In contrast, men with job authority have fewer symptoms of depression than men without such power." The study, "Gender, Job Authority, and Depression," published in the December ...

Real-time genome sequencing helps control hospital outbreak

2014-11-20
Pioneering use of whole genome sequencing in real time to help control a hospital outbreak is reported in an article published in the open access journal Genome Medicine. The research corroborates the use of the technique as a rapid and cost-effective way of tracking and controlling the spread of drug-resistant hospital pathogens. Acinetobacter baumannii is a multi-drug resistant pathogen found in hospitals across the globe and emerged as a significant threat to casualties in the Iraq and Afghanistan wars. It affects severely ill patients, particularly trauma and burns ...

Sun's rotating 'magnet' pulls lightning towards UK

2014-11-20
The Sun may be playing a part in the generation of lightning strikes on Earth by temporarily 'bending' the Earth's magnetic field and allowing a shower of energetic particles to enter the upper atmosphere. This is according to researchers at the University of Reading who have found that over a five year period the UK experienced around 50% more lightning strikes when the Earth's magnetic field was skewed by the Sun's own magnetic field. The Earth's magnetic field usually functions as an in-built force-field to shield against a bombardment of particles from space, known ...

Terrorist attacks decrease fertility levels, says new research

2014-11-20
A new study published online today in the journal Oxford Economic Papers has found that, on average, terrorist attacks decrease fertility, reducing both the expected number of children a woman has over her lifetime and the number of live births occurring during each year. In recent years, terrorism has grown as a significant factor affecting our lives in unforeseen ways. Much has been written regarding the causes of terrorism, yet the ramifications of prolonged exposure to terrorism are still to be thoroughly studied. This new study, carried out by Dr. Claude Berrebi ...

Queen's researchers prove for the first time that ash clouds can cross Atlantic Ocean

2014-11-20
Scientists at Queen's University Belfast have led the discovery of a volcanic ash cloud that travelled from Alaska to Northern Ireland and beyond - overturning previously held assumptions about how far ash deposits can drift, with major implications for the airline industry. The discovery, which was made in partnership with an international team of academics and has been published in the journal Geology, is the first evidence that ash clouds can travel across the Atlantic Ocean, confirming Queen's as a global leader in research. This particular ash, found in sites across ...

Researchers identify biological indicator of response to new ovarian cancer drug

2014-11-20
Barcelona, Spain: Researchers have found a way of identifying which ovarian cancer patients are likely to respond well to a new anti-cancer drug called rucaparib. Results of clinical trials have shown that women with tumours that are sensitive to platinum-based chemotherapy and who carry inherited mutations in the BRCA1/2 genes respond well to rucaparib. But in new findings presented today (Thursday) at the 26th EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain, researchers say that they have identified a biological indicator ...

Researchers pioneer new approach to treating HPV-related cervical cancer

2014-11-20
Barcelona, Spain: A drug that is already well established as a treatment for infection of the retina in people with AIDS has been shown, for the first time, to sensitise cervical cancer to chemotherapy and radiotherapy without an increase in toxic side-effects. Cidofovir is an anti-viral drug that is effective against several viruses, including the human papilloma virus (HPV), which is implicated in the onset of cervical cancer. It targets the cancer-causing proteins (oncoproteins) produced by HPV. These oncoproteins interfere with the action of other proteins that control ...

Response to new drug in patients with lymphomas and advanced solid tumors

2014-11-20
Barcelona, Spain: Patients with B-cell Non-Hodgkin lymphomas and advanced solid tumours have responded to a new drug that is being tested for the first time in humans in a phase I clinical trial. Preliminary results from the trial will be presented today (Thursday) at the 26th EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain. They show responses in four lymphoma patients who have failed numerous previous treatments and also in one patient with a cancer for which there is no approved medical treatment at all - a malignant rhabdoid ...

Bad marriage, broken heart?

Bad marriage, broken heart?
2014-11-20
EAST LANSING, Mich. --- Older couples in a bad marriage -- particularly female spouses -- have a higher risk for heart disease than those in a good marriage, finds the first nationally representative study of its kind. The findings suggest the need for marriage counseling and programs aimed at promoting marital quality and well-being for couples into their 70s and 80s, said lead investigator Hui Liu, a Michigan State University sociologist. "Marriage counseling is focused largely on younger couples," said Liu, associate professor of sociology. "But these results show ...

Pac-Man instead of patch: Using video games to improve lazy eye, depth perception

Pac-Man instead of patch: Using video games to improve lazy eye, depth perception
2014-11-20
WASHINGTON, D.C. - Scientists have created video games that add an important element of fun to the repetitive training needed to improve vision in people - including adults - with a lazy eye and poor depth perception. The training tools, including a Pac-Man-style "cat and mouse" game and a "search for oddball" game, have produced results in pilot testing: Weak-eye vision improved to 20/20 and 20/50 in two adult research participants with lazy eyes whose vision was 20/25 and 20/63, respectively, before the training began. Unlike the common use of eye patches on dominant ...

The Affordable Care Act in Kentucky, one year later

2014-11-20
LOUISVILLE, Ky. - One year ago, Michael Stillman, M.D., and his colleague, Monalisa Tailor, M.D., both physicians with the University of Louisville Department of Medicine, wrote a New England Journal of Medicine "Perspective" article about "Tommy Davis," their pseudonym-named patient who delayed seeing a doctor because he lacked health insurance. After spending a year experiencing severe abdominal pain and other symptoms, Davis finally sought care in the emergency room. The diagnosis? Metastatic colon cancer. "If we'd found it sooner," Davis said to the physicians, ...

A signature for success

2014-11-20
November 19, 2014, New York, NY - A team led by Ludwig and Memorial Sloan Kettering (MSK) researchers has published a landmark study on the genetic basis of response to a powerful cancer therapy known as immune checkpoint blockade. Their paper, in the current issue of the New England Journal of Medicine, describes the precise genetic signatures in melanoma tumors that determine whether a patient will respond to one such therapy. It also explains in exquisite detail how those genetic profiles translate into subtle molecular changes that enable the immune system attack of ...

New leadless pacemaker safe, reliable

2014-11-19
A new self-contained leadless cardiac pacemaker is a safe and reliable alternative to conventional pacemakers, according to research presented at the American Heart Association's Scientific Sessions 2014. The new device reduces complications that have existed over the last 50 years that are associated with lead placement and performance and the pulse generator situated under the skin that have occurred with conventional pacemaker systems. In the first trial of the leadless pacemaker, doctors implanted one in eight patients (average 82 years old, 75 percent men) with ...

More children surviving dilated cardiomyopathy without heart transplant

2014-11-19
More children with dilated cardiomyopathy are surviving without a heart transplant, according to research presented at the American Heart Association's Scientific Sessions 2014. Dilated cardiomyopathy occurs when the heart is enlarged (dilated) and the pumping chambers contract poorly (usually left side is worse than right). It can have genetic and infectious/environmental causes. Researchers analyzed the clinical outcomes of children with dilated cardiomyopathy in the NHLBI Pediatric Cardiomyopathy Registry (PCMR) and divided them into two groups based upon year of ...

Unhealthy behavior may be cross-generational

2014-11-19
Children whose parents spend a lot of time sitting in front of a computer or other screen are more likely than other children to have excessive screen-time habits, as well as associated risks for heart and blood vessel disease, according to a study presented at the American Heart Association's Scientific Sessions 2014. "Screen time of children is significantly associated with parental screen time," said Masao Yoshinaga, M.D., Ph.D., the study's lead author and chief director of pediatrics at National Hospital Organization, Kagoshima Medical Center in Japan. "To reduce ...

From architect to social worker: Complex jobs may protect memory and thinking later on

2014-11-19
MINNEAPOLIS - People whose jobs require more complex work with other people, such as social workers and lawyers, or with data, like architects or graphic designers, may end up having longer-lasting memory and thinking abilities compared to people who do less complex work, according to research published in the November 19, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. "These results suggest that more stimulating work environments may help people retain their thinking skills, and that this might be observed years after ...

Johns Hopkins scientists present findings at the Society for Neuroscience meeting

2014-11-19
Nanosymposium 18.10 Sat., 3:15 p.m., Walter E. Washington Convention Center, 150A Lindsay Hayes and Akira Sawa A Blood Pressure Hormone Implicated in Psychosis In an effort to find a marker that predicts psychosis, postdoctoral researcher Lindsay Hayes, Ph.D., learned unexpectedly that mice and people with behavior disorders have abnormally low levels of a hormone system tied to blood pressure regulation and inflammation. In the cerebrospinal fluid of patients with first episode psychosis, she noticed abnormally low levels of the enzyme that makes the hormone angiotensin. ...
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