Using wash cloths in jails shows promise for reducing costly infections
2014-11-25
CHICAGO (November 25, 2014) - New research shows providing detainees wash cloths treated with a skin cleanser could reduce the prevalence of Staphylococcus aureus (S. aureus) bacteria in U.S. jails. Researchers looked at the effect on transmission of S. aureus of using wash cloths treated with chlorhexidine gluconate (CHG) compared with wash cloths with only plain water in detainees at Dallas County Jail. The study was published in the December issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America (SHEA). ...
Superbug in SE Michigan shows recent decline
2014-11-25
CHICAGO (November 25, 2014) - A new study finds a decrease in an emergent strain of methicillin-resistant S. aureus (MRSA) that is resistant to last line defense antibiotics. Researchers examined the prevalence of vancomycin-resistant Staphylococcus aureus (VRSA) infections in southeastern Michigan, where the majority of these infections have occurred in the U.S. The study is published in the December issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America (SHEA).
"Vancomycin is one of the few antimicrobial ...
Vanderbilt team uses e-health records to search for hidden drug benefits
2014-11-25
With research and development costs for many drugs reaching well into the billions, pharmaceutical companies want more than ever to determine whether their drugs already at market have any hidden therapeutic benefits that could warrant putting additional indications on the label and increase production.
Such repurposing of drugs requires evidence of efficacy, and to find candidate drugs for randomized controlled repurposing trials, investigators can use computer simulation and scans of health care billing data, in addition to in vitro and in vivo testing.
A study led ...
Trojan horse tactic gives parasites edge over immune systems
2014-11-25
Parasites use Trojan horse subterfuge to suppress the immunity of their victims when causing infection, according to a study.
The finding, which shows a new trick parasites can play, paves the way to possible treatments for infectious diseases and allergies.
Scientists have shown that parasites are able to secrete tiny sealed packages of genetic material into the cells of their victims, in order to suppress the immune response to infection.
The packages, known as vesicles, mimic those that are produced naturally in most organisms to carry out everyday functions such ...
Researchers shed new light on the genetics of memory performance
2014-11-25
(Boston)-- In the largest study of the genetics of memory ever undertaken, an international researcher team including scientists from Boston University School of Medicine (BUSM), have discovered two common genetic variants that are believed to be associated with memory performance. The findings, which appear in the journal Biological Psychiatry, are a significant step towards better understanding how memory loss is inherited.
Longer life spans and the increased prevalence of memory impairment and dementia world-wide underscore the critical public health importance of ...
A hybrid vehicle that delivers DNA
2014-11-25
BUFFALO, N.Y. - A new hybrid vehicle is under development.
Its performance isn't measured by the distance it travels, but rather the delivery of its cargo: vaccines that contain genetically engineered DNA to fight HIV, cancer, influenza and other maladies.
Described recently in the Proceedings of the National Academy of Sciences, the technology is a biomedical advancement that could help unleash the potential of DNA vaccines, which despite two decades of research, have yet to make a significant impact in the treatment of major illnesses.
"The technology that we're developing ...
Pathology specialist contributes to debate on breast cancer gene screening
2014-11-25
There has been much recent debate on the benefits and risks of screening for breast cancer using BRCA1 and BRCA2 mutations in the general adult population. With an estimated 235,000 new breast cancer diagnoses each year in the U.S. and more than 40,000 deaths, it is clearly important to be able to determine which women may be genetically predisposed to breast cancer.
Glenn E. Palomaki, PhD, associate director of the Division of Medical Screening and Special Testing in the Department of Pathology and Laboratory Medicine at Women & Infants Hospital of Rhode Island has ...
Study supports free 'super Wi-Fi'
2014-11-25
This news release is available in German.
Wireless data transmission largely takes place via WLAN networks, such as WiFi. However, these networks are currently limited to high frequency ranges at 2 GHz and above and, hence, have a limited range. The authors of the study, Arnd Weber of the Institute for Technology Assessment and Systems Analysis (ITAS) of KIT and Jens Elsner, a former member of the staff of the KIT Communications Engineering Lab, propose to extend the frequencies for free communication to include lower ranges and even increased transmission power. ...
Athletes' testosterone surges not tied to winning, study finds
2014-11-25
A higher surge of testosterone in competition, the so-called "winner effect," is not actually related to winning, suggests a new study of intercollegiate cross country runners.
The International Journal of Exercise Science published the research, led by David Edwards, a professor of psychology at Emory University, and his graduate student Kathleen Casto.
"Many people in the scientific literature and in popular culture link testosterone increases to winning," Casto says. "In this study, however, we found an increase in testosterone during a race regardless of the athletes' ...
Mining can damage fish habitats far downstream, study shows
2014-11-25
Anglers across the nation wondering why luck at their favorite fishing spot seems to have dried up may have a surprising culprit: a mine miles away, even in a different state.
Scientists at Michigan State University (MSU) have taken a first broad look at the impacts of mines across the country- and found that mining can damage fish habitats miles downstream, and even in streams not directly connected to the mines.
The work is published in this week's issue of the journal Ecological Indicators.
"We've been surprised that even a single mine in headwaters might influence ...
Incomes fall as stressed economy struggles
2014-11-25
Australian average incomes are falling with the country's population growth "masking underlying economic weakness", according to a QUT economist.
Dr Mark McGovern, a senior lecturer in QUT's Business School, said while it was regularly proclaimed Australia had experienced positive economic growth for more than 20 years, there had been periodic per capita declines, indicating the economy was not as healthy as assumed.
"Looking at national income figures in recent years shows our economy is under stress," Dr McGovern, whose research was recently published in the Economic ...
Circumstances are right for weed invasion to escalate, researchers say
2014-11-25
Few agribusinesses or governments regulate the types of plants that farmers use in their pastures to feed their livestock, according to an international team of researchers that includes one plant scientist from Virginia Tech.
The problem is most of these so-called pasture plants are invasive weeds.
In a Proceedings of the National Academy of Sciences study this month, the scientists recommended tighter regulations, including a fee for damage to surrounding areas, evaluation of weed risk to the environment, a list of prohibited species based on this risk, and closer ...
NIH scientists determine how environment contributes to several human diseases
2014-11-25
Using a new imaging technique, National Institutes of Health researchers have found that the biological machinery that builds DNA can insert molecules into the DNA strand that are damaged as a result of environmental exposures. These damaged molecules trigger cell death that produces some human diseases, according to the researchers. The work, appearing online Nov. 17 in the journal Nature, provides a possible explanation for how one type of DNA damage may lead to cancer, diabetes, hypertension, cardiovascular and lung disease, and Alzheimer's disease.
Time-lapse crystallography ...
Study maps how city neighborhoods affect diabetes risk
2014-11-25
PHILADELPHIA (Nov. 25, 2014) - As the linked epidemics of obesity and diabetes continue to escalate, a staggering one in five U.S. adults is projected to have diabetes by 2050.
Ground zero for identifying ways to slow and stop that rise is Philadelphia, which has the highest diabetes rate among the nation's largest cities. For public health researchers at Drexel University, it is also a prime location to learn how neighborhood and community-level factors -- not just individual factors like diet, exercise and education-- influence people's risk.
A new Drexel study published ...
International team reveals barriers to public health data-sharing; life-saving solutions
2014-11-25
PITTSBURGH, Nov. 24, 2014 -Barriers to the sharing of public health data hamper decision-making efforts on local, national and global levels, and stymie attempts to contain emerging global health threats, an international team led by the University of Pittsburgh Graduate School of Public Health announced today.
The analysis, published in the journal BMC Public Health and funded by the Bill & Melinda Gates Foundation and the National Institutes of Health (NIH), classifies and examines the barriers in order to open a focused international dialogue on solutions.
"Data on ...
Body size requires hormones under control
2014-11-25
The proper regulation of body size is of fundamental importance, but the mechanisms that stop growth are still unclear. In a study now published in the scientific journal eLife*, a research group from Instituto Gulbenkian de Ciência (IGC), led by Christen Mirth, shed new light on how animals regulate body size. The researchers uncovered important clues about the molecular mechanisms triggered by environmental conditions that ultimately affect final body size. They show that the timing of synthesis of a steroid hormone called ecdysone is sensitive to nutrition in the ...
Feeling -- not being -- wealthy drives opposition to wealth redistribution
2014-11-25
People's views on income inequality and wealth distribution may have little to do with how much money they have in the bank and a lot to do with how wealthy they feel in comparison to their friends and neighbors, according to new findings published in Psychological Science, a journal of the Association for Psychological Science.
"Our research shows that subjective feelings of wealth or poverty motivate people's attitudes toward redistribution, quite independently of objective self-interest," says psychological scientist and study co-author Keith Payne of the University ...
Why fruit flies could lead to better beer (video)
2014-11-25
WASHINGTON, Nov. 25, 2014 -- Your beer may attract annoying fruit flies, but listen up before you give them a swat. Researchers found the yeast cells in beer are producing odor compounds -- acetate esters -- that lure flies and that could lead to the best beer you haven't even tasted yet. This week's Speaking of Chemistry explains why. Check it out at http://youtu.be/HQNlGuZvCvA.
Speaking of Chemistry is a production of Chemical & Engineering News, a weekly magazine of the American Chemical Society. The program features fascinating, weird and otherwise interesting chemistry ...
Virtual money: User's identity can be revealed much easier than thought
2014-11-25
Bitcoin is the new money: minted and exchanged on the Internet. Faster and cheaper than a bank, the service is attracting attention from all over the world. But a big question remains: are the transactions really anonymous? Several research groups worldwide have shown that it is possible to find out which transactions belong together, even if the client uses different pseudonyms. However it was not clear if it is also possible to reveal the IP address behind each transaction. This has changed: researchers at the University of Luxembourg have now demonstrated how this is ...
Few operations for epilepsy despite their safety and efficacy
2014-11-25
The study at Sahlgrenska Academy, University of Gothenburg, was based on the Swedish National Epilepsy Surgery Register, which includes all cases since 1990. The researchers reviewed data for the 865 patients who were operated on at Sweden's six epilepsy surgery clinics from 1996 to 2010.
The purpose of surgery is to enable a person with severe epilepsy to be free of seizures or to reduce their frequency to the point that (s)he can enjoy better quality of life.
Downward trend
Only 3% (25) of the patients suffered lasting complications. A comparison with a previous ...
Researchers find way to turn sawdust into gasoline
2014-11-25
Researchers at KU Leuven's Centre for Surface Chemistry and Catalysis have successfully converted sawdust into building blocks for gasoline. Using a new chemical process, they were able to convert the cellulose in sawdust into hydrocarbon chains. These hydrocarbons can be used as an additive in gasoline, or as a component in plastics. The researchers reported their findings in the journal Energy & Environmental Science.
Cellulose is the main substance in plant matter and is present in all non-edible plant parts of wood, straw, grass, cotton and old paper. "At the molecular ...
'Dramatic' early phase 1 results for AG-120 in IDH1 mutated AML
2014-11-25
Results presented November 19 by University of Colorado Cancer Center investigator Daniel Pollyea, MD, MS, at the 26th European Organisation for Research and Treatment of Cancer Symposium in Barcelona show "extremely promising" early phase 1 clinical trial results for the investigational drug AG-120 against the subset of patients with acute myeloid leukemia (AML) harboring mutations in the gene IDH1. The finding builds on phase 1 results of a related drug, AG-221, against IDH2 mutations, presented at the most recent meeting of the American Association for Cancer Research. ...
Johns Hopkins scientists link gene to tamoxifen-resistant breast cancers
2014-11-25
After mining the genetic records of thousands of breast cancer patients, researchers from the Johns Hopkins Kimmel Cancer Center have identified a gene whose presence may explain why some breast cancers are resistant to tamoxifen, a widely used hormone treatment generally used after surgery, radiation and other chemotherapy.
The gene, called MACROD2, might also be useful in screening for some aggressive forms of breast cancers, and, someday, offering a new target for therapy, says Ben Ho Park, M.D., Ph.D., an associate professor of oncology in the Kimmel Cancer Center's ...
Policing Canada in the 21st century: New policing for new challenges
2014-11-25
A new expert panel report, Policing Canada in the 21st Century: New Policing for New Challenges, released today by the Council of Canadian Academies, details the complexity and global nature of policing in the modern age. Overall, a 12-member Expert Panel determined that safety and security cannot just rest with Canada's policing services. Specialists, public and private security services, and other first responders all have a vital role to play in an interconnected safety and security web. This transition has already begun in Canada and around the world. A central challenge ...
Problem gambling, personality disorders often go hand in hand
2014-11-25
The treatment of people who cannot keep their gambling habits in check is often complicated because they also tend to suffer from personality disorders. So says Meredith Brown of Monash University in Australia, in a review in Springer's Journal of Gambling Studies.
Problem gambling creates a multitude of intrapersonal, interpersonal and social difficulties for the roughly 2.3 percent of the population internationally that suffers from this behavior. Previous research has shown that people with gambling problems suffer from a range of psychiatric disorders affecting their ...
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